-
1
-
-
53549133654
-
Reading and writing DNA methylation.
-
Jeltsch A. Reading and writing DNA methylation. Nat Struct Mol Biol 2008: 15: 1003-1004.
-
(2008)
Nat Struct Mol Biol
, vol.15
, pp. 1003-1004
-
-
Jeltsch, A.1
-
2
-
-
0019318994
-
DNA methylation and gene function.
-
Razin A, Riggs AD. DNA methylation and gene function. Science 1980: 210: 604-610.
-
(1980)
Science
, vol.210
, pp. 604-610
-
-
Razin, A.1
Riggs, A.D.2
-
4
-
-
0027141519
-
Number of CpG islands and genes in human and mouse.
-
Antequera F, Bird A. Number of CpG islands and genes in human and mouse. Proc Natl Acad Sci U S A 1993: 90: 11995-11999.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 11995-11999
-
-
Antequera, F.1
Bird, A.2
-
5
-
-
0025006860
-
High levels of de novo methylation and altered chromatin structure at CpG islands in cell lines.
-
Antequera F, Boyes J, Bird A. High levels of de novo methylation and altered chromatin structure at CpG islands in cell lines. Cell 1990: 62: 503-514.
-
(1990)
Cell
, vol.62
, pp. 503-514
-
-
Antequera, F.1
Boyes, J.2
Bird, A.3
-
6
-
-
0026989172
-
Abnormal regional hypermethylation in cancer cells.
-
Baylin SB. Abnormal regional hypermethylation in cancer cells. AIDS Res Hum Retroviruses 1992: 8: 811-820.
-
(1992)
AIDS Res Hum Retroviruses
, vol.8
, pp. 811-820
-
-
Baylin, S.B.1
-
7
-
-
0020486108
-
Substrate and sequence specificity of a eukaryotic DNA methylase.
-
Gruenbaum Y, Cedar H, Razin A. Substrate and sequence specificity of a eukaryotic DNA methylase. Nature 1982: 295: 620-622.
-
(1982)
Nature
, vol.295
, pp. 620-622
-
-
Gruenbaum, Y.1
Cedar, H.2
Razin, A.3
-
8
-
-
70450217879
-
Human DNA methylomes at base resolution show widespread epigenomic differences.
-
Lister R, Pelizzola M, Dowen RH et al. Human DNA methylomes at base resolution show widespread epigenomic differences. Nature 2009: 462: 315-322.
-
(2009)
Nature
, vol.462
, pp. 315-322
-
-
Lister, R.1
Pelizzola, M.2
Dowen, R.H.3
-
9
-
-
77958503799
-
A dynamic methylome; implications of non-CG methylation/demethylation.
-
Szyf M. A dynamic methylome; implications of non-CG methylation/demethylation. Cell Cycle 2010: 9: 3846-3847.
-
(2010)
Cell Cycle
, vol.9
, pp. 3846-3847
-
-
Szyf, M.1
-
10
-
-
79951677959
-
DNA methylase and demethylase activities are modulated by one-carbon metabolism in Alzheimer's disease models.
-
Fuso A, Nicolia V, Cavallaro RA, Scarpa S. DNA methylase and demethylase activities are modulated by one-carbon metabolism in Alzheimer's disease models. J Nutr Biochem 2011: 22: 242-251.
-
(2011)
J Nutr Biochem
, vol.22
, pp. 242-251
-
-
Fuso, A.1
Nicolia, V.2
Cavallaro, R.A.3
Scarpa, S.4
-
11
-
-
0033615717
-
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development.
-
Okano M, Bell DW, Haber DA, Li E. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 1999: 99: 247-257.
-
(1999)
Cell
, vol.99
, pp. 247-257
-
-
Okano, M.1
Bell, D.W.2
Haber, D.A.3
Li, E.4
-
12
-
-
66149123748
-
The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain.
-
Kriaucionis S, Heintz N. The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain. Science 2009: 324: 929-930.
-
(2009)
Science
, vol.324
, pp. 929-930
-
-
Kriaucionis, S.1
Heintz, N.2
-
13
-
-
78650172154
-
Sustained calcium signalling and caspase-3 activation involve NMDA receptors in thymocytes in contact with dendritic cells.
-
Affaticati P, Mignen O, Jambou F et al. Sustained calcium signalling and caspase-3 activation involve NMDA receptors in thymocytes in contact with dendritic cells. Cell Death Differ 2011: 18: 99-108.
-
(2011)
Cell Death Differ
, vol.18
, pp. 99-108
-
-
Affaticati, P.1
Mignen, O.2
Jambou, F.3
-
14
-
-
80052461558
-
Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine.
-
Ito S, Shen L, Dai Q et al. Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine. Science 2011: 333: 1300-1303.
-
(2011)
Science
, vol.333
, pp. 1300-1303
-
-
Ito, S.1
Shen, L.2
Dai, Q.3
-
15
-
-
0021168535
-
DNA methylation patterns. Formation and function.
-
Razin A, Szyf M. DNA methylation patterns. Formation and function. Biochim Biophys Acta 1984: 782: 331-342.
-
(1984)
Biochim Biophys Acta
, vol.782
, pp. 331-342
-
-
Razin, A.1
Szyf, M.2
-
16
-
-
0021927762
-
Tissue-specific hypomethylation and expression of rat phosphoenolpyruvate carboxykinase gene induced by in vivo treatment of fetuses and neonates with 5-azacytidine.
-
Benvenisty N, Szyf M, Mencher D, Razin A, Reshef L. Tissue-specific hypomethylation and expression of rat phosphoenolpyruvate carboxykinase gene induced by in vivo treatment of fetuses and neonates with 5-azacytidine. Biochemistry 1985: 24: 5015-5019.
-
(1985)
Biochemistry
, vol.24
, pp. 5015-5019
-
-
Benvenisty, N.1
Szyf, M.2
Mencher, D.3
Razin, A.4
Reshef, L.5
-
17
-
-
58849091905
-
A human B cell methylome at 100-base pair resolution.
-
Rauch TA, Wu X, Zhong X, Riggs AD, Pfeifer GP. A human B cell methylome at 100-base pair resolution. Proc Natl Acad Sci U S A 2009: 106: 671-678.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 671-678
-
-
Rauch, T.A.1
Wu, X.2
Zhong, X.3
Riggs, A.D.4
Pfeifer, G.P.5
-
18
-
-
33847304609
-
Gene body-specific methylation on the active X chromosome.
-
Hellman A, Chess A. Gene body-specific methylation on the active X chromosome. Science 2007: 315: 1141-1143.
-
(2007)
Science
, vol.315
, pp. 1141-1143
-
-
Hellman, A.1
Chess, A.2
-
19
-
-
80555157482
-
Late-replicating heterochromatin is characterized by decreased cytosine methylation in the human genome.
-
Suzuki M, Oda M, Ramos MP et al. Late-replicating heterochromatin is characterized by decreased cytosine methylation in the human genome. Genome Res 2011: 21: 1833-1840.
-
(2011)
Genome Res
, vol.21
, pp. 1833-1840
-
-
Suzuki, M.1
Oda, M.2
Ramos, M.P.3
-
20
-
-
79955538247
-
Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain.
-
Guo JU, Su Y, Zhong C, Ming GL, Song H. Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain. Cell 2011: 145: 423-434.
-
(2011)
Cell
, vol.145
, pp. 423-434
-
-
Guo, J.U.1
Su, Y.2
Zhong, C.3
Ming, G.L.4
Song, H.5
-
21
-
-
80052495940
-
Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA.
-
He YF, Li BZ, Li Z et al. Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA. Science 2011: 333: 1303-1307.
-
(2011)
Science
, vol.333
, pp. 1303-1307
-
-
He, Y.F.1
Li, B.Z.2
Li, Z.3
-
22
-
-
79956308473
-
Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells.
-
Pastor WA, Pape UJ, Huang Y et al. Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells. Nature 2011: 473: 394-397.
-
(2011)
Nature
, vol.473
, pp. 394-397
-
-
Pastor, W.A.1
Pape, U.J.2
Huang, Y.3
-
23
-
-
79960249232
-
Genomic mapping of 5-hydroxymethylcytosine in the human brain.
-
Jin SG, Wu X, Li AX, Pfeifer GP. Genomic mapping of 5-hydroxymethylcytosine in the human brain. Nucleic Acids Res 2011: 39: 5015-5024.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 5015-5024
-
-
Jin, S.G.1
Wu, X.2
Li, A.X.3
Pfeifer, G.P.4
-
24
-
-
79954457998
-
Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells.
-
Wu H, D'Alessio AC, Ito S et al. Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells. Genes Dev 2011: 25: 679-684.
-
(2011)
Genes Dev
, vol.25
, pp. 679-684
-
-
Wu, H.1
D'Alessio, A.C.2
Ito, S.3
-
25
-
-
79961125686
-
Tet1 and 5-hydroxymethylation: a genome-wide view in mouse embryonic stem cells.
-
Wu H, Zhang Y. Tet1 and 5-hydroxymethylation: a genome-wide view in mouse embryonic stem cells. Cell Cycle 2011: 10: 2428-2436.
-
(2011)
Cell Cycle
, vol.10
, pp. 2428-2436
-
-
Wu, H.1
Zhang, Y.2
-
26
-
-
0009832780
-
In vitro methylation of the hamster adenine phosphoribosyltransferase gene inhibits its expression in mouse L cells.
-
Stein R, Razin A, Cedar H. In vitro methylation of the hamster adenine phosphoribosyltransferase gene inhibits its expression in mouse L cells. Proc Natl Acad Sci U S A 1982: 79: 3418-3422.
-
(1982)
Proc Natl Acad Sci U S A
, vol.79
, pp. 3418-3422
-
-
Stein, R.1
Razin, A.2
Cedar, H.3
-
27
-
-
0025294471
-
CpG methylation inhibits proenkephalin gene expression and binding of the transcription factor AP-2.
-
Comb M, Goodman HM. CpG methylation inhibits proenkephalin gene expression and binding of the transcription factor AP-2. Nucleic Acids Res 1990: 18: 3975-3982.
-
(1990)
Nucleic Acids Res
, vol.18
, pp. 3975-3982
-
-
Comb, M.1
Goodman, H.M.2
-
28
-
-
0026198118
-
CpG methylation inhibits binding of several sequence-specific DNA-binding proteins from pea, wheat, soybean and cauliflower.
-
Inamdar NM, Ehrlich KC, Ehrlich M. CpG methylation inhibits binding of several sequence-specific DNA-binding proteins from pea, wheat, soybean and cauliflower. Plant Mol Biol 1991: 17: 111-123.
-
(1991)
Plant Mol Biol
, vol.17
, pp. 111-123
-
-
Inamdar, N.M.1
Ehrlich, K.C.2
Ehrlich, M.3
-
29
-
-
0342437491
-
MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin.
-
Nan X, Campoy FJ, Bird A. MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin. Cell 1997: 88: 471-481.
-
(1997)
Cell
, vol.88
, pp. 471-481
-
-
Nan, X.1
Campoy, F.J.2
Bird, A.3
-
30
-
-
0043093697
-
Transposable elements: targets for early nutritional effects on epigenetic gene regulation.
-
Waterland RA, Jirtle RL. Transposable elements: targets for early nutritional effects on epigenetic gene regulation. Mol Cell Biol 2003: 23: 5293-5300.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 5293-5300
-
-
Waterland, R.A.1
Jirtle, R.L.2
-
31
-
-
34548715144
-
Maternal nutrient supplementation counteracts bisphenol A-induced DNA hypomethylation in early development.
-
Dolinoy DC, Huang D, Jirtle RL. Maternal nutrient supplementation counteracts bisphenol A-induced DNA hypomethylation in early development. Proc Natl Acad Sci U S A 2007: 104: 13056-13061.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 13056-13061
-
-
Dolinoy, D.C.1
Huang, D.2
Jirtle, R.L.3
-
32
-
-
79961221664
-
The early life social environment and DNA methylation; DNA methylation mediating the long-term impact of social environments early in life.
-
Szyf M. The early life social environment and DNA methylation; DNA methylation mediating the long-term impact of social environments early in life. Epigenetics 2011: 6: 971-978.
-
(2011)
Epigenetics
, vol.6
, pp. 971-978
-
-
Szyf, M.1
-
33
-
-
0034748330
-
Using an interactive framework of society and lifecourse to explain self-rated health in early adulthood.
-
Hertzman C, Power C, Matthews S, Manor O. Using an interactive framework of society and lifecourse to explain self-rated health in early adulthood. Soc Sci Med 2001: 53: 1575-1585.
-
(2001)
Soc Sci Med
, vol.53
, pp. 1575-1585
-
-
Hertzman, C.1
Power, C.2
Matthews, S.3
Manor, O.4
-
34
-
-
0030778884
-
Social differences in health: life-cycle effects between ages 23 and 33 in the 1958 British birth cohort.
-
Power C, Hertzman C, Matthews S et al. Social differences in health: life-cycle effects between ages 23 and 33 in the 1958 British birth cohort. Am J Public Health 1997: 87: 1499-1503.
-
(1997)
Am J Public Health
, vol.87
, pp. 1499-1503
-
-
Power, C.1
Hertzman, C.2
Matthews, S.3
-
35
-
-
33751547498
-
Associations of early growth and adult adiposity with patterns of salivary cortisol in adulthood.
-
Power C, Li L, Hertzman C. Associations of early growth and adult adiposity with patterns of salivary cortisol in adulthood. J Clin Endocrinol Metab 2006: 91: 4264-4270.
-
(2006)
J Clin Endocrinol Metab
, vol.91
, pp. 4264-4270
-
-
Power, C.1
Li, L.2
Hertzman, C.3
-
36
-
-
0017188707
-
A 10-year perspective of motherless-mother monkey behavior.
-
Ruppenthal GC, Arling GL, Harlow HF, Sackett GP, Suomi SJ. A 10-year perspective of motherless-mother monkey behavior. J Abnorm Psychol 1976: 85: 341-349.
-
(1976)
J Abnorm Psychol
, vol.85
, pp. 341-349
-
-
Ruppenthal, G.C.1
Arling, G.L.2
Harlow, H.F.3
Sackett, G.P.4
Suomi, S.J.5
-
38
-
-
15144344289
-
Maternal care, hippocampal glucocorticoid receptors, and hypothalamic-pituitary-adrenal responses to stress.
-
Liu D, Diorio J, Tannenbaum B et al. Maternal care, hippocampal glucocorticoid receptors, and hypothalamic-pituitary-adrenal responses to stress. Science 1997: 277: 1659-1662.
-
(1997)
Science
, vol.277
, pp. 1659-1662
-
-
Liu, D.1
Diorio, J.2
Tannenbaum, B.3
-
39
-
-
0033527727
-
Nongenomic transmission across generations of maternal behavior and stress responses in the rat.
-
Francis D, Diorio J, Liu D, Meaney MJ. Nongenomic transmission across generations of maternal behavior and stress responses in the rat. Science 1999: 286: 1155-1158.
-
(1999)
Science
, vol.286
, pp. 1155-1158
-
-
Francis, D.1
Diorio, J.2
Liu, D.3
Meaney, M.J.4
-
40
-
-
84879165572
-
Long-term effects of differential early rearing in rhesus macaques: behavioral reactivity in adulthood.
-
Corcoran CA, Pierre PJ, Haddad T et al. Long-term effects of differential early rearing in rhesus macaques: behavioral reactivity in adulthood. Dev Psychobiol 2011.
-
(2011)
Dev Psychobiol
-
-
Corcoran, C.A.1
Pierre, P.J.2
Haddad, T.3
-
41
-
-
60449117336
-
Risk and resilience: early manipulation of macaque social experience and persistent behavioral and neurophysiological outcomes.
-
Stevens HE, Leckman JF, Coplan JD, Suomi SJ. Risk and resilience: early manipulation of macaque social experience and persistent behavioral and neurophysiological outcomes. J Am Acad Child Adolesc Psychiatry 2009: 48: 114-127.
-
(2009)
J Am Acad Child Adolesc Psychiatry
, vol.48
, pp. 114-127
-
-
Stevens, H.E.1
Leckman, J.F.2
Coplan, J.D.3
Suomi, S.J.4
-
42
-
-
61849179516
-
Early life stress as a risk factor for mental health: role of neurotrophins from rodents to non-human primates.
-
Cirulli F, Francia N, Berry A et al. Early life stress as a risk factor for mental health: role of neurotrophins from rodents to non-human primates. Neurosci Biobehav Rev 2009: 33: 573-585.
-
(2009)
Neurosci Biobehav Rev
, vol.33
, pp. 573-585
-
-
Cirulli, F.1
Francia, N.2
Berry, A.3
-
43
-
-
0025937795
-
Early stress and adult emotional reactivity in rhesus monkeys.
-
discussion 183-188.
-
Suomi SJ. Early stress and adult emotional reactivity in rhesus monkeys. Ciba Found Symp 1991: 156: 171-183; discussion 183-188.
-
(1991)
Ciba Found Symp
, vol.156
, pp. 171-183
-
-
Suomi, S.J.1
-
45
-
-
0034176639
-
Active demethylation of the paternal genome in the mouse zygote.
-
Oswald J, Engemann S, Lane N et al. Active demethylation of the paternal genome in the mouse zygote. Curr Biol 2000: 10: 475-478.
-
(2000)
Curr Biol
, vol.10
, pp. 475-478
-
-
Oswald, J.1
Engemann, S.2
Lane, N.3
-
46
-
-
0035831505
-
The dynamics of myogenin site-specific demethylation is strongly correlated with its expression and with muscle differentiation.
-
Lucarelli M, Fuso A, Strom R, Scarpa S. The dynamics of myogenin site-specific demethylation is strongly correlated with its expression and with muscle differentiation. J Biol Chem 2001: 276: 7500-7506.
-
(2001)
J Biol Chem
, vol.276
, pp. 7500-7506
-
-
Lucarelli, M.1
Fuso, A.2
Strom, R.3
Scarpa, S.4
-
47
-
-
0037340215
-
Selective, stable demethylation of the interleukin-2 gene enhances transcription by an active process.
-
Bruniquel D, Schwartz RH. Selective, stable demethylation of the interleukin-2 gene enhances transcription by an active process. Nat Immunol 2003: 4: 235-240.
-
(2003)
Nat Immunol
, vol.4
, pp. 235-240
-
-
Bruniquel, D.1
Schwartz, R.H.2
-
48
-
-
0021770264
-
An estrogen-dependent demethylation at the 5′ end of the chicken vitellogenin gene is independent of DNA synthesis.
-
Wilks A, Seldran M, Jost JP. An estrogen-dependent demethylation at the 5′ end of the chicken vitellogenin gene is independent of DNA synthesis. Nucleic Acids Res 1984: 12: 1163-1177.
-
(1984)
Nucleic Acids Res
, vol.12
, pp. 1163-1177
-
-
Wilks, A.1
Seldran, M.2
Jost, J.P.3
-
49
-
-
0029055763
-
Ras induces a general DNA demethylation activity in mouse embryonal P19 cells.
-
Szyf M, Theberge J, Bozovic V. Ras induces a general DNA demethylation activity in mouse embryonal P19 cells. J Biol Chem 1995: 270: 12690-12696.
-
(1995)
J Biol Chem
, vol.270
, pp. 12690-12696
-
-
Szyf, M.1
Theberge, J.2
Bozovic, V.3
-
50
-
-
34447334574
-
Peptidyl argininedeiminase 2 CpG island in multiple sclerosis white matter is hypomethylated.
-
Mastronardi FG, Noor A, Wood DD, Paton T, Moscarello MA. Peptidyl argininedeiminase 2 CpG island in multiple sclerosis white matter is hypomethylated. J Neurosci Res 2007: 85: 2006-2016.
-
(2007)
J Neurosci Res
, vol.85
, pp. 2006-2016
-
-
Mastronardi, F.G.1
Noor, A.2
Wood, D.D.3
Paton, T.4
Moscarello, M.A.5
-
51
-
-
51649127761
-
Clozapine and sulpiride but not haloperidol or olanzapine activate brain DNA demethylation.
-
Dong E, Nelson M, Grayson DR, Costa E, Guidotti A. Clozapine and sulpiride but not haloperidol or olanzapine activate brain DNA demethylation. Proc Natl Acad Sci U S A 2008: 105: 13614-13619.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 13614-13619
-
-
Dong, E.1
Nelson, M.2
Grayson, D.R.3
Costa, E.4
Guidotti, A.5
-
53
-
-
77950187447
-
Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons.
-
Feng J, Zhou Y, Campbell SL et al. Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons. Nat Neurosci 2010: 13: 423-430.
-
(2010)
Nat Neurosci
, vol.13
, pp. 423-430
-
-
Feng, J.1
Zhou, Y.2
Campbell, S.L.3
-
54
-
-
33744920106
-
Evidence that DNA (cytosine-5) methyltransferase regulates synaptic plasticity in the hippocampus.
-
Levenson JM, Roth TL, Lubin FD et al. Evidence that DNA (cytosine-5) methyltransferase regulates synaptic plasticity in the hippocampus. J Biol Chem 2006: 281: 15763-15773.
-
(2006)
J Biol Chem
, vol.281
, pp. 15763-15773
-
-
Levenson, J.M.1
Roth, T.L.2
Lubin, F.D.3
-
55
-
-
33847614418
-
Covalent modification of DNA regulates memory formation.
-
Miller CA, Sweatt JD. Covalent modification of DNA regulates memory formation. Neuron 2007: 53: 857-869.
-
(2007)
Neuron
, vol.53
, pp. 857-869
-
-
Miller, C.A.1
Sweatt, J.D.2
-
56
-
-
71749084889
-
The role of DNA methylation in the central nervous system and neuropsychiatric disorders.
-
Feng J, Fan G. The role of DNA methylation in the central nervous system and neuropsychiatric disorders. Int Rev Neurobiol 2009: 89: 67-84.
-
(2009)
Int Rev Neurobiol
, vol.89
, pp. 67-84
-
-
Feng, J.1
Fan, G.2
-
57
-
-
0033580326
-
A mammalian protein with specific demethylase activity for mCpG DNA.
-
Bhattacharya SK, Ramchandani S, Cervoni N, Szyf M. A mammalian protein with specific demethylase activity for mCpG DNA. Nature 1999: 397: 579-583.
-
(1999)
Nature
, vol.397
, pp. 579-583
-
-
Bhattacharya, S.K.1
Ramchandani, S.2
Cervoni, N.3
Szyf, M.4
-
58
-
-
0027310491
-
Nuclear extracts of chicken embryos promote an active demethylation of DNA by excision repair of 5-methyldeoxycytidine.
-
Jost JP. Nuclear extracts of chicken embryos promote an active demethylation of DNA by excision repair of 5-methyldeoxycytidine. Proc Natl Acad Sci U S A 1993: 90: 4684-4688.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 4684-4688
-
-
Jost, J.P.1
-
59
-
-
0345676675
-
Replacement of 5-methylcytosine by cytosine: a possible mechanism for transient DNA demethylation during differentiation.
-
Razin A, Szyf M, Kafri T et al. Replacement of 5-methylcytosine by cytosine: a possible mechanism for transient DNA demethylation during differentiation. Proc Natl Acad Sci U S A 1986: 83: 2827-2831.
-
(1986)
Proc Natl Acad Sci U S A
, vol.83
, pp. 2827-2831
-
-
Razin, A.1
Szyf, M.2
Kafri, T.3
-
60
-
-
40449104358
-
Transient cyclical methylation of promoter DNA.
-
Kangaspeska S, Stride B, Metivier R et al. Transient cyclical methylation of promoter DNA. Nature 2008: 452: 112-115.
-
(2008)
Nature
, vol.452
, pp. 112-115
-
-
Kangaspeska, S.1
Stride, B.2
Metivier, R.3
-
61
-
-
33846933274
-
Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation.
-
Barreto G, Schafer A, Marhold J et al. Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation. Nature 2007: 445: 671-675.
-
(2007)
Nature
, vol.445
, pp. 671-675
-
-
Barreto, G.1
Schafer, A.2
Marhold, J.3
-
62
-
-
41949136533
-
GADD45A does not promote DNA demethylation.
-
Jin SG, Guo C, Pfeifer GP. GADD45A does not promote DNA demethylation. PLoS Genet 2008: 4: e1000013.
-
(2008)
PLoS Genet
, vol.4
-
-
Jin, S.G.1
Guo, C.2
Pfeifer, G.P.3
-
63
-
-
60749094831
-
Neuronal activity-induced Gadd45b promotes epigenetic DNA demethylation and adult neurogenesis.
-
Ma DK, Jang MH, Guo JU et al. Neuronal activity-induced Gadd45b promotes epigenetic DNA demethylation and adult neurogenesis. Science 2009: 323: 1074-1077.
-
(2009)
Science
, vol.323
, pp. 1074-1077
-
-
Ma, D.K.1
Jang, M.H.2
Guo, J.U.3
-
64
-
-
57649196594
-
DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45.
-
Rai K, Huggins IJ, James SR et al. DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45. Cell 2008: 135: 1201-1212.
-
(2008)
Cell
, vol.135
, pp. 1201-1212
-
-
Rai, K.1
Huggins, I.J.2
James, S.R.3
-
65
-
-
77249148019
-
Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency.
-
Popp C, Dean W, Feng S et al. Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency. Nature 2010: 463: 1101-1105.
-
(2010)
Nature
, vol.463
, pp. 1101-1105
-
-
Popp, C.1
Dean, W.2
Feng, S.3
-
66
-
-
77956189495
-
Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification.
-
Ito S, D'Alessio AC, Taranova OV et al. Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification. Nature 2010: 466: 1129-1133.
-
(2010)
Nature
, vol.466
, pp. 1129-1133
-
-
Ito, S.1
D'Alessio, A.C.2
Taranova, O.V.3
-
67
-
-
80053348585
-
The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes.
-
Gu TP, Guo F, Yang H et al. The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes. Nature 2011: 477: 606-610.
-
(2011)
Nature
, vol.477
, pp. 606-610
-
-
Gu, T.P.1
Guo, F.2
Yang, H.3
-
68
-
-
80054097425
-
Replication-dependent loss of 5-hydroxymethylcytosine in mouse preimplantation embryos.
-
Inoue A, Zhang Y. Replication-dependent loss of 5-hydroxymethylcytosine in mouse preimplantation embryos. Science 2011: 334: 194.
-
(2011)
Science
, vol.334
, pp. 194
-
-
Inoue, A.1
Zhang, Y.2
-
69
-
-
33847055935
-
Endogenous cytosine damage products alter the site selectivity of human DNA maintenance methyltransferase DNMT1.
-
Valinluck V, Sowers LC. Endogenous cytosine damage products alter the site selectivity of human DNA maintenance methyltransferase DNMT1. Cancer Res 2007: 67: 946-950.
-
(2007)
Cancer Res
, vol.67
, pp. 946-950
-
-
Valinluck, V.1
Sowers, L.C.2
-
70
-
-
0036145567
-
Dynamic reprogramming of DNA methylation in the early mouse embryo.
-
Santos F, Hendrich B, Reik W, Dean W. Dynamic reprogramming of DNA methylation in the early mouse embryo. Dev Biol 2002: 241: 172-182.
-
(2002)
Dev Biol
, vol.241
, pp. 172-182
-
-
Santos, F.1
Hendrich, B.2
Reik, W.3
Dean, W.4
-
71
-
-
79952763586
-
Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine.
-
Iqbal K, Jin SG, Pfeifer GP, Szabo PE. Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine. Proc Natl Acad Sci U S A 2011: 108: 3642-3647.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 3642-3647
-
-
Iqbal, K.1
Jin, S.G.2
Pfeifer, G.P.3
Szabo, P.E.4
-
72
-
-
70149103800
-
Mutation in TET2 in myeloid cancers.
-
author reply 1117-1118.
-
Tefferi A, Lim KH, Levine R. Mutation in TET2 in myeloid cancers. N Engl J Med 2009: 361: 1117; author reply 1117-1118.
-
(2009)
N Engl J Med
, vol.361
, pp. 1117
-
-
Tefferi, A.1
Lim, K.H.2
Levine, R.3
-
73
-
-
77953037018
-
Mutations of the TET2 and CBL genes: novel molecular markers in myeloid malignancies.
-
Bacher U, Haferlach C, Schnittger S et al. Mutations of the TET2 and CBL genes: novel molecular markers in myeloid malignancies. Ann Hematol 2010: 89: 643-652.
-
(2010)
Ann Hematol
, vol.89
, pp. 643-652
-
-
Bacher, U.1
Haferlach, C.2
Schnittger, S.3
-
74
-
-
78650175023
-
Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2.
-
Ko M, Huang Y, Jankowska AM et al. Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2. Nature 2010: 468: 839-843.
-
(2010)
Nature
, vol.468
, pp. 839-843
-
-
Ko, M.1
Huang, Y.2
Jankowska, A.M.3
-
75
-
-
33644763991
-
Maternal care effects on the hippocampal transcriptome and anxiety-mediated behaviors in the offspring that are reversible in adulthood.
-
Weaver IC, Meaney MJ, Szyf M. Maternal care effects on the hippocampal transcriptome and anxiety-mediated behaviors in the offspring that are reversible in adulthood. Proc Natl Acad Sci U S A 2006: 103: 3480-3485.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 3480-3485
-
-
Weaver, I.C.1
Meaney, M.J.2
Szyf, M.3
-
76
-
-
28044436691
-
Reversal of maternal programming of stress responses in adult offspring through methyl supplementation: altering epigenetic marking later in life.
-
Weaver IC, Champagne FA, Brown SE et al. Reversal of maternal programming of stress responses in adult offspring through methyl supplementation: altering epigenetic marking later in life. J Neurosci 2005: 25: 11045-11054.
-
(2005)
J Neurosci
, vol.25
, pp. 11045-11054
-
-
Weaver, I.C.1
Champagne, F.A.2
Brown, S.E.3
-
77
-
-
63449085750
-
Lasting epigenetic influence of early-life adversity on the BDNF gene.
-
Roth TL, Lubin FD, Funk AJ, Sweatt JD. Lasting epigenetic influence of early-life adversity on the BDNF gene. Biol Psychiatry 2009: 65: 760-769.
-
(2009)
Biol Psychiatry
, vol.65
, pp. 760-769
-
-
Roth, T.L.1
Lubin, F.D.2
Funk, A.J.3
Sweatt, J.D.4
-
78
-
-
70549104872
-
Dynamic DNA methylation programs persistent adverse effects of early-life stress.
-
Murgatroyd C, Patchev AV, Wu Y et al. Dynamic DNA methylation programs persistent adverse effects of early-life stress. Nat Neurosci 2009: 12: 1559-1566.
-
(2009)
Nat Neurosci
, vol.12
, pp. 1559-1566
-
-
Murgatroyd, C.1
Patchev, A.V.2
Wu, Y.3
-
79
-
-
34347352117
-
Epigenetic programming of the rRNA promoter by MBD3.
-
Brown SE, Szyf M. Epigenetic programming of the rRNA promoter by MBD3. Mol Cell Biol 2007: 27: 4938-4952.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 4938-4952
-
-
Brown, S.E.1
Szyf, M.2
-
80
-
-
47749133462
-
Promoter-wide hypermethylation of the ribosomal RNA gene promoter in the suicide brain.
-
McGowan PO, Sasaki A, Huang TC et al. Promoter-wide hypermethylation of the ribosomal RNA gene promoter in the suicide brain. PLoS One 2008: 3: e2085.
-
(2008)
PLoS One
, vol.3
-
-
McGowan, P.O.1
Sasaki, A.2
Huang, T.C.3
-
81
-
-
60749105468
-
Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse.
-
McGowan PO, Sasaki A, D'Alessio AC et al. Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse. Nat Neurosci 2009: 12: 342-348.
-
(2009)
Nat Neurosci
, vol.12
, pp. 342-348
-
-
McGowan, P.O.1
Sasaki, A.2
D'Alessio, A.C.3
-
82
-
-
0028968980
-
Effect of bacterial endotoxin and interleukin-1 beta on hippocampal serotonergic neurotransmission, behavioral activity, and free corticosterone levels: an in vivo microdialysis study.
-
Linthorst AC, Flachskamm C, Muller-Preuss P, Holsboer F, Reul JM. Effect of bacterial endotoxin and interleukin-1 beta on hippocampal serotonergic neurotransmission, behavioral activity, and free corticosterone levels: an in vivo microdialysis study. J Neurosci 1995: 15: 2920-2934.
-
(1995)
J Neurosci
, vol.15
, pp. 2920-2934
-
-
Linthorst, A.C.1
Flachskamm, C.2
Muller-Preuss, P.3
Holsboer, F.4
Reul, J.M.5
-
83
-
-
52949099506
-
GABAA receptor promoter hypermethylation in suicide brain: implications for the involvement of epigenetic processes.
-
Poulter MO, Du L, Weaver IC et al. GABAA receptor promoter hypermethylation in suicide brain: implications for the involvement of epigenetic processes. Biol Psychiatry 2008: 64: 645-652.
-
(2008)
Biol Psychiatry
, vol.64
, pp. 645-652
-
-
Poulter, M.O.1
Du, L.2
Weaver, I.C.3
-
84
-
-
58149523262
-
Alternative splicing, methylation state, and expression profile of tropomyosin-related kinase B in the frontal cortex of suicide completers.
-
Ernst C, Deleva V, Deng X et al. Alternative splicing, methylation state, and expression profile of tropomyosin-related kinase B in the frontal cortex of suicide completers. Arch Gen Psychiatry 2009: 66: 22-32.
-
(2009)
Arch Gen Psychiatry
, vol.66
, pp. 22-32
-
-
Ernst, C.1
Deleva, V.2
Deng, X.3
-
85
-
-
79952212084
-
Broad epigenetic signature of maternal care in the brain of adult rats.
-
McGowan PO, Suderman M, Sasaki A et al. Broad epigenetic signature of maternal care in the brain of adult rats. PLoS One 2011: 6: e14739.
-
(2011)
PLoS One
, vol.6
-
-
McGowan, P.O.1
Suderman, M.2
Sasaki, A.3
-
86
-
-
84858436920
-
Associations with early-life socio-economic position in adult DNA methylation.
-
Borghol N, Suderman M, McArdle W et al. Associations with early-life socio-economic position in adult DNA methylation. Int J Epidemiol 2011: 1-13.
-
(2011)
Int J Epidemiol
, pp. 1-13
-
-
Borghol, N.1
Suderman, M.2
McArdle, W.3
-
87
-
-
47149100122
-
Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses.
-
Oberlander TF, Weinberg J, Papsdorf M et al. Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses. Epigenetics 2008: 3: 97-106.
-
(2008)
Epigenetics
, vol.3
, pp. 97-106
-
-
Oberlander, T.F.1
Weinberg, J.2
Papsdorf, M.3
-
88
-
-
79952171975
-
Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor.
-
Ressler KJ, Mercer KB, Bradley B et al. Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor. Nature 2011: 470: 492-497.
-
(2011)
Nature
, vol.470
, pp. 492-497
-
-
Ressler, K.J.1
Mercer, K.B.2
Bradley, B.3
-
89
-
-
84862760961
-
Telomere length and early severe social deprivation: linking early adversity and cellular aging.
-
Drury SS, Theall K, Gleason MM et al. Telomere length and early severe social deprivation: linking early adversity and cellular aging. Mol Psychiatry 2011.
-
(2011)
Mol Psychiatry
-
-
Drury, S.S.1
Theall, K.2
Gleason, M.M.3
-
90
-
-
68149084026
-
The economics and psychology of inequality and human development.
-
Cunha F, Heckman JJ. The economics and psychology of inequality and human development. J Eur Econ Assoc 2009: 7: 320-364.
-
(2009)
J Eur Econ Assoc
, vol.7
, pp. 320-364
-
-
Cunha, F.1
Heckman, J.J.2
-
91
-
-
34547839782
-
Life-course influences on health in British adults: effects of socio-economic position in childhood and adulthood.
-
Power C, Atherton K, Strachan DP et al. Life-course influences on health in British adults: effects of socio-economic position in childhood and adulthood. Int J Epidemiol 2007: 36: 532-539.
-
(2007)
Int J Epidemiol
, vol.36
, pp. 532-539
-
-
Power, C.1
Atherton, K.2
Strachan, D.P.3
|