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Volumn 4, Issue 2, 2012, Pages 233-242

Selective killing of Kaposi's sarcoma-associated herpesvirus lytically infected cells with a recombinant immunotoxin targeting the viral gpK8.1A envelope glycoprotein

Author keywords

Ganciclovir; Human herpesvirus 8; KSHV lytic infection; KSHV surface glycoprotein; Multicentric Castleman disease; Pseudomonas exotoxin A; Reciprocal drug potentiation; Targeted cytotoxic proteins

Indexed keywords

ANTIVIRUS AGENT; GANCICLOVIR; GLYCOPROTEIN GPK8.1A; IMMUNOTOXIN; RECOMBINANT IMMUNOTOXIN 2014 PE38; UNCLASSIFIED DRUG; VIRUS DNA; VIRUS ENVELOPE PROTEIN; VIRUS GLYCOPROTEIN; GLYCOPROTEIN; K8.1 PROTEIN, HUMAN HERPESVIRUS 8; RECOMBINANT PROTEIN; VIRUS ANTIBODY; VIRUS PROTEIN;

EID: 84858266126     PISSN: 19420862     EISSN: 19420870     Source Type: Journal    
DOI: 10.4161/mabs.4.2.19262     Document Type: Article
Times cited : (15)

References (95)
  • 1
    • 35348962397 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus
    • Knipe DM, Howley PM, Eds. Philadelphia, PA: Lippincott Williams and Wilkins
    • Ganem D. Kaposi's sarcoma-associated herpesvirus. In: Knipe DM, Howley PM, Eds. Fields Virology. Philadelphia, PA: Lippincott Williams and Wilkins 2007; 5:2847-88.
    • (2007) Fields Virology , vol.5 , pp. 2847-2888
    • Ganem, D.1
  • 2
    • 36349022047 scopus 로고    scopus 로고
    • The family Herpesviridae: A brief introduction
    • Knipe DM, Howley PM, Eds. Fifth Edition. Philadelphia: Lipincott Williams & Wilkens
    • Pellett PE, Roizman B. The family Herpesviridae: a brief introduction. In: Knipe DM, Howley PM, Eds. Fields Virology, Fifth Edition. Philadelphia: Lipincott Williams & Wilkens 2007; 2479-99.
    • (2007) Fields Virology , pp. 2479-2499
    • Pellett, P.E.1    Roizman, B.2
  • 3
    • 76849087997 scopus 로고    scopus 로고
    • Kaposi sarcoma-associated herpesvirus (KSHV): Molecular biology and oncogenesis
    • PMID:19651473
    • Wen KW, Damania B. Kaposi sarcoma-associated herpesvirus (KSHV): molecular biology and oncogenesis. Cancer Lett 2010; 289:140-50; PMID:19651473; http://dx.doi.org/10.1016/j.canlet.2009.07.004.
    • (2010) Cancer Lett , vol.289 , pp. 140-150
    • Wen, K.W.1    Damania, B.2
  • 4
    • 0028588064 scopus 로고
    • Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma
    • PMID:7997879
    • Chang Y, Cesarman E, Pessin MS, Lee F, Culpepper J, Knowles DM, et al. Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma. Science 1994; 266:1865-9; PMID:7997879; http://dx.doi.org/10.1126/ science.7997879.
    • (1994) Science , vol.266 , pp. 1865-1869
    • Chang, Y.1    Cesarman, E.2    Pessin, M.S.3    Lee, F.4    Culpepper, J.5    Knowles, D.M.6
  • 5
    • 0029069445 scopus 로고
    • Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas
    • PMID:7700311
    • Cesarman E, Chang Y, Moore PS, Said JW, Knowles DM. Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas. N Engl J Med 1995; 332:1186-91; PMID:7700311; http://dx.doi.org/10.1056/NEJM199505043321802.
    • (1995) N Engl J Med , vol.332 , pp. 1186-1191
    • Cesarman, E.1    Chang, Y.2    Moore, P.S.3    Said, J.W.4    Knowles, D.M.5
  • 6
    • 0029166033 scopus 로고
    • Kaposi's sarcoma-associated herpesvirus-like DNA sequences in multicentric Castleman's disease
    • PMID:7632932
    • Soulier J, Grollet L, Oksenhendler E, Cacoub P, Cazals-Hatem D, Babinet P, et al. Kaposi's sarcoma-associated herpesvirus-like DNA sequences in multicentric Castleman's disease. Blood 1995; 86:1276-80; PMID:7632932.
    • (1995) Blood , vol.86 , pp. 1276-1280
    • Soulier, J.1    Grollet, L.2    Oksenhendler, E.3    Cacoub, P.4    Cazals-Hatem, D.5    Babinet, P.6
  • 7
    • 0242608521 scopus 로고    scopus 로고
    • Kaposi?s sarcoma-associated herpesvirus immunoevasion and tumorigenesis: Two sides of the same coin?
    • PMID:14527293
    • Moore PS, Chang Y. Kaposi?s sarcoma-associated herpesvirus immunoevasion and tumorigenesis: two sides of the same coin? Annu Rev Microbiol 2003; 57:609-39; PMID:14527293; http://dx.doi.org/10.1146/annurev.micro.57.030502. 090824.
    • (2003) Annu Rev Microbiol , vol.57 , pp. 609-639
    • Moore, P.S.1    Chang, Y.2
  • 8
    • 53349095351 scopus 로고    scopus 로고
    • HIV/AIDS: Epidemiology, pathophysiology and treatment of Kaposi sarcoma-associated herpesvirus disease: Kaposi sarcoma, primary effusion lymphoma and multicentric Castleman disease
    • PMID:18808357
    • Sullivan RJ, Pantanowitz L, Casper C, Stebbing J, Dezube BJ. HIV/AIDS: epidemiology, pathophysiology and treatment of Kaposi sarcoma-associated herpesvirus disease: Kaposi sarcoma, primary effusion lymphoma and multicentric Castleman disease. Clin Infect Dis 2008; 47:1209-15; PMID:18808357; http://dx.doi.org/10.1086/592298.
    • (2008) Clin Infect Dis , vol.47 , pp. 1209-1215
    • Sullivan, R.J.1    Pantanowitz, L.2    Casper, C.3    Stebbing, J.4    Dezube, B.J.5
  • 9
    • 79960275404 scopus 로고    scopus 로고
    • Human herpesvirus 8-associated neoplasms: The roles of viral replication and antiviral treatment
    • PMID:21666458
    • Gantt S, Casper C. Human herpesvirus 8-associated neoplasms: the roles of viral replication and antiviral treatment. Curr Opin Infect Dis 2011; 24:295-301; PMID:21666458; http://dx.doi.org/10.1097/QCO.0b013e3283486d04.
    • (2011) Curr Opin Infect Dis , vol.24 , pp. 295-301
    • Gantt, S.1    Casper, C.2
  • 10
    • 79955465167 scopus 로고    scopus 로고
    • Gammaherpesvirus and lymphoproliferative disorders in immunocompromised patients
    • PMID:21493001
    • Cesarman E. Gammaherpesvirus and lymphoproliferative disorders in immunocompromised patients. Cancer Lett 2011; 305:163-74; PMID:21493001; http://dx.doi.org/10.1016/j.canlet.2011.03.003.
    • (2011) Cancer Lett , vol.305 , pp. 163-174
    • Cesarman, E.1
  • 11
    • 0034630323 scopus 로고    scopus 로고
    • Expression and localization of human herpesvirus 8-encoded proteins in primary effusion lymphoma, Kaposi's sarcoma and multicentric Castleman?s disease
    • PMID:10753712
    • Katano H, Sato Y, Kurata T, Mori S, Sata T. Expression and localization of human herpesvirus 8-encoded proteins in primary effusion lymphoma, Kaposi's sarcoma and multicentric Castleman?s disease. Virology 2000; 269:335-44; PMID:10753712; http://dx.doi.org/10.1006/viro.2000.0196.
    • (2000) Virology , vol.269 , pp. 335-344
    • Katano, H.1    Sato, Y.2    Kurata, T.3    Mori, S.4    Sata, T.5
  • 12
    • 0033901248 scopus 로고    scopus 로고
    • Differential viral protein expression in Kaposi's sarcoma-associated herpesvirus-infected diseases: Kaposi?s sarcoma, primary effusion lymphoma and multicentric Castleman's disease
    • PMID:10702388
    • Parravicini C, Chandran B, Corbellino M, Berti E, Paulli M, Moore PS, et al. Differential viral protein expression in Kaposi's sarcoma-associated herpesvirus-infected diseases: Kaposi?s sarcoma, primary effusion lymphoma and multicentric Castleman's disease. Am J Pathol 2000; 156:743-9; PMID:10702388; http://dx.doi.org/10.1016/S0002-9440(10)64940-1.
    • (2000) Am J Pathol , vol.156 , pp. 743-749
    • Parravicini, C.1    Chandran, B.2    Corbellino, M.3    Berti, E.4    Paulli, M.5    Moore, P.S.6
  • 13
    • 33644881083 scopus 로고    scopus 로고
    • Quantitative analysis of Kaposi sarcoma-associated herpesvirus (KSHV) in KSHV-associated diseases
    • PMID:16479510
    • Asahi-Ozaki Y, Sato Y, Kanno T, Sata T, Katano H. Quantitative analysis of Kaposi sarcoma-associated herpesvirus (KSHV) in KSHV-associated diseases. J Infect Dis 2006; 193:773-82; PMID:16479510; http://dx.doi.org/10.1086/500560.
    • (2006) J Infect Dis , vol.193 , pp. 773-782
    • Asahi-Ozaki, Y.1    Sato, Y.2    Kanno, T.3    Sata, T.4    Katano, H.5
  • 14
    • 77952577452 scopus 로고    scopus 로고
    • Distinct profiles of antibodies to Kaposi sarcoma-associated herpesvirus antigens in patients with Kaposi sarcoma, multicentric Castleman disease and primary effusion lymphoma
    • PMID:20443737
    • Burbelo PD, Issa AT, Ching KH, Wyvill KM, Little RF, Iadarola MJ, et al. Distinct profiles of antibodies to Kaposi sarcoma-associated herpesvirus antigens in patients with Kaposi sarcoma, multicentric Castleman disease and primary effusion lymphoma. J Infect Dis 2010; 201:1919-22; PMID:20443737; http://dx.doi.org/10.1086/652869.
    • (2010) J Infect Dis , vol.201 , pp. 1919-1922
    • Burbelo, P.D.1    Issa, A.T.2    Ching, K.H.3    Wyvill, K.M.4    Little, R.F.5    Iadarola, M.J.6
  • 16
    • 67849111384 scopus 로고    scopus 로고
    • HIV-associated multicentric Castleman disease
    • PMID:19343828
    • Oksenhendler E. HIV-associated multicentric Castleman disease. Curr Opin HIV AIDS 2009; 4:16-21; PMID:19343828; http://dx.doi.org/10.1097/COH. 0b013e328319bca9.
    • (2009) Curr Opin HIV AIDS , vol.4 , pp. 16-21
    • Oksenhendler, E.1
  • 17
    • 68849122422 scopus 로고    scopus 로고
    • Castleman disease: An update on classification and the spectrum of associated lesions
    • PMID:19546611
    • Cronin DMP, Warnke RA. Castleman disease: an update on classification and the spectrum of associated lesions. Adv Anat Pathol 2009; 16:236-46; PMID:19546611; http://dx.doi.org/10.1097/PAP.0b013e3181a9d4d3.
    • (2009) Adv Anat Pathol , vol.16 , pp. 236-246
    • Cronin, D.M.P.1    Warnke, R.A.2
  • 18
    • 79959300575 scopus 로고    scopus 로고
    • Clinical features and outcome in HIV-associated multicentric Castleman's disease
    • PMID:21555697
    • Bower M, Newsom-Davis T, Naresh K, Merchant S, Lee B, Gazzard B, et al. Clinical features and outcome in HIV-associated multicentric Castleman's disease. J Clin Oncol 2011; 29:2481-6; PMID:21555697; http://dx.doi.org/10.1200/ JCO.2010.34.1909.
    • (2011) J Clin Oncol , vol.29 , pp. 2481-2486
    • Bower, M.1    Newsom-Davis, T.2    Naresh, K.3    Merchant, S.4    Lee, B.5    Gazzard, B.6
  • 19
    • 0034665781 scopus 로고    scopus 로고
    • High levels of human herpesvirus 8 viral load, human interleukin-6, interleukin- 10 and C reactive protein correlate with exacerbation of multicentric castleman disease in HIV-infected patients
    • PMID:10979949
    • Oksenhendler E, Carcelain G, Aoki Y, Boulanger E, Maillard A, Clauvel JP, et al. High levels of human herpesvirus 8 viral load, human interleukin-6, interleukin- 10 and C reactive protein correlate with exacerbation of multicentric castleman disease in HIV-infected patients. Blood 2000; 96:2069-73; PMID:10979949.
    • (2000) Blood , vol.96 , pp. 2069-2073
    • Oksenhendler, E.1    Carcelain, G.2    Aoki, Y.3    Boulanger, E.4    Maillard, A.5    Clauvel, J.P.6
  • 20
    • 79960514270 scopus 로고    scopus 로고
    • Plasma HHV8 DNA predicts relapse in individuals with HIV-associated multicentric Castleman disease
    • PMID:21511959
    • Stebbing J, Adams C, Sanitt A, Mletzko S, Nelson M, Gazzard B, et al. Plasma HHV8 DNA predicts relapse in individuals with HIV-associated multicentric Castleman disease. Blood 2011; 118:271-5; PMID:21511959; http://dx.doi.org/10. 1182/blood-2011-02-335620.
    • (2011) Blood , vol.118 , pp. 271-275
    • Stebbing, J.1    Adams, C.2    Sanitt, A.3    Mletzko, S.4    Nelson, M.5    Gazzard, B.6
  • 21
    • 18744387452 scopus 로고    scopus 로고
    • Kaposi's sarcoma in the era of HAART-an update on mechanisms, diagnostics and treatment
    • PMID:15875661
    • Dittmer DP, Vahrson W, Staudt M, Hilscher C, Fakhari FD. Kaposi's sarcoma in the era of HAART-an update on mechanisms, diagnostics and treatment. AIDS Rev 2005; 7:56-61; PMID:15875661.
    • (2005) AIDS Rev , vol.7 , pp. 56-61
    • Dittmer, D.P.1    Vahrson, W.2    Staudt, M.3    Hilscher, C.4    Fakhari, F.D.5
  • 22
    • 63549095091 scopus 로고    scopus 로고
    • The role of immune suppression and HHV-8 in the increasing incidence of HIV-associated multicentric Castleman's disease
    • PMID:19179554
    • Powles T, Stebbing J, Bazeos A, Hatzimichael E, Mandalia S, Nelson M, et al. The role of immune suppression and HHV-8 in the increasing incidence of HIV-associated multicentric Castleman's disease. Ann Oncol 2009; 20:775-9; PMID:19179554; http://dx.doi.org/10.1093/annonc/mdn697.
    • (2009) Ann Oncol , vol.20 , pp. 775-779
    • Powles, T.1    Stebbing, J.2    Bazeos, A.3    Hatzimichael, E.4    Mandalia, S.5    Nelson, M.6
  • 24
    • 78649480343 scopus 로고    scopus 로고
    • How I treat HIV-associated multicentric Castleman disease
    • PMID:20688959
    • Bower M. How I treat HIV-associated multicentric Castleman disease. Blood 2010; 116:4415-21; PMID:20688959; http://dx.doi.org/10.1182/blood-2010-07- 290213.
    • (2010) Blood , vol.116 , pp. 4415-4421
    • Bower, M.1
  • 25
    • 79955556128 scopus 로고    scopus 로고
    • Castleman's disease: From basic mechanisms to molecular therapeutics
    • PMID:21441298
    • El-Osta HE, Kurzrock R. Castleman's disease: from basic mechanisms to molecular therapeutics. Oncologist 2011; 16:497-511; PMID:21441298; http://dx.doi.org/10.1634/theoncologist.2010-0212.
    • (2011) Oncologist , vol.16 , pp. 497-511
    • El-Osta, H.E.1    Kurzrock, R.2
  • 26
    • 34250198300 scopus 로고    scopus 로고
    • Anti-interleukin-6 receptor antibody (tocilizumab) treatment of multicentric Castleman's disease
    • PMID:17541233
    • Matsuyama M, Suzuki T, Tsuboi H, Ito S, Mamura M, Goto D, et al. Anti-interleukin-6 receptor antibody (tocilizumab) treatment of multicentric Castleman's disease. Intern Med 2007; 46:771-4; PMID:17541233; http://dx.doi.org/10.2169/internalmedicine.46.6262.
    • (2007) Intern Med , vol.46 , pp. 771-774
    • Matsuyama, M.1    Suzuki, T.2    Tsuboi, H.3    Ito, S.4    Mamura, M.5    Goto, D.6
  • 27
    • 77957283115 scopus 로고    scopus 로고
    • Siltuximab, a novel anti-interleukin- 6 monoclonal antibody, for Castleman's disease
    • PMID:20625121
    • van Rhee F, Fayad L, Voorhees P, Furman R, Lonial S, Borghaei H, et al. Siltuximab, a novel anti-interleukin- 6 monoclonal antibody, for Castleman's disease. J Clin Oncol 2010; 28:3701-8; PMID:20625121; http://dx.doi.org/10.1200/ JCO.2009.27.2377.
    • (2010) J Clin Oncol , vol.28 , pp. 3701-3708
    • Van Rhee, F.1    Fayad, L.2    Voorhees, P.3    Furman, R.4    Lonial, S.5    Borghaei, H.6
  • 28
    • 34548232784 scopus 로고    scopus 로고
    • Prospective study of rituximab in chemotherapy-dependent human immunodeficiency virus associated multicentric Castleman's disease: ANRS 117 CastlemaB Trial
    • PMID:17664482
    • G?rard L, B?rezn? A, Galicier L, Meignin V, Obadia M, De Castro N, et al. Prospective study of rituximab in chemotherapy-dependent human immunodeficiency virus associated multicentric Castleman's disease: ANRS 117 CastlemaB Trial. J Clin Oncol 2007; 25:3350-6; PMID:17664482; http://dx.doi.org/10.1200/JCO.2007. 10.6732.
    • (2007) J Clin Oncol , vol.25 , pp. 3350-3356
    • Gérard, L.1    Bérezn, A.2    Galicier, L.3    Meignin, V.4    Obadia, M.5    De Castro, N.6
  • 29
    • 38449113389 scopus 로고    scopus 로고
    • Brief communication: Rituximab in HIV-associated multicentric Castleman disease
    • PMID:18087054
    • Bower M, Powles T, Williams S, Davis TN, Atkins M, Montoto S, et al. Brief communication: rituximab in HIV-associated multicentric Castleman disease. Ann Intern Med 2007; 147:836-9; PMID:18087054.
    • (2007) Ann Intern Med , vol.147 , pp. 836-839
    • Bower, M.1    Powles, T.2    Williams, S.3    Davis, T.N.4    Atkins, M.5    Montoto, S.6
  • 30
    • 44349092406 scopus 로고    scopus 로고
    • Multicentric Castleman's disease treated with combination chemotherapy and rituximab in four HIV-positive men: A case series
    • PMID:18027834
    • Bestawros A, Michel R, S?guin C, Routy JP. Multicentric Castleman's disease treated with combination chemotherapy and rituximab in four HIV-positive men: a case series. Am J Hematol 2008; 83:508-11; PMID:18027834; http://dx.doi.org/10.1002/ajh.21108.
    • (2008) Am J Hematol , vol.83 , pp. 508-511
    • Bestawros, A.1    Michel, R.2    Séguin, C.3    Routy, J.P.4
  • 31
    • 51649101044 scopus 로고    scopus 로고
    • Successful treatment of multicentric Castleman's disease with combined immunochemotherapy in an AIDS patient with multiorgan failure
    • PMID:18449205
    • Schmidt SM, Raible A, Kort?m F, Mayer F, Riessen R, Adam P, et al. Successful treatment of multicentric Castleman's disease with combined immunochemotherapy in an AIDS patient with multiorgan failure. Leukemia 2008; 22:1782-5; PMID:18449205; http://dx.doi.org/10.1038/leu.2008.54.
    • (2008) Leukemia , vol.22 , pp. 1782-1785
    • Schmidt, S.M.1    Raible, A.2    Kortüm, F.3    Mayer, F.4    Riessen, R.5    Adam, P.6
  • 32
    • 77950918526 scopus 로고    scopus 로고
    • Development of Kaposi's sarcoma after complete remission of multicentric Castlemans disease with rituximab therapy in a HHV8-positive, HIV-negative patient
    • PMID:20146033
    • Law AB, Ryan G, Lade S, Prince HM. Development of Kaposi's sarcoma after complete remission of multicentric Castlemans disease with rituximab therapy in a HHV8-positive, HIV-negative patient. Int J Hematol 2010; 91:347-8; PMID:20146033; http://dx.doi.org/10.1007/s12185-010-0497-9.
    • (2010) Int J Hematol , vol.91 , pp. 347-348
    • Law, A.B.1    Ryan, G.2    Lade, S.3    Prince, H.M.4
  • 33
    • 67651184064 scopus 로고    scopus 로고
    • Treatment of multicentric Castleman's Disease accompanying multiple myeloma with bortezomib: A case report
    • PMID:19400935
    • Yuan ZG, Dun XY, Li YH, Hou J. Treatment of multicentric Castleman's Disease accompanying multiple myeloma with bortezomib: a case report. J Hematol Oncol 2009; 2:19; PMID:19400935; http://dx.doi.org/10.1186/1756-8722-2-19.
    • (2009) J Hematol Oncol , vol.2 , pp. 19
    • Yuan, Z.G.1    Dun, X.Y.2    Li, Y.H.3    Hou, J.4
  • 34
    • 1442308113 scopus 로고    scopus 로고
    • Remission of HHV-8 and HIV-associated multicentric Castleman disease with ganciclovir treatment
    • PMID:14615380
    • Casper C, Nichols WG, Huang ML, Corey L, Wald A. Remission of HHV-8 and HIV-associated multicentric Castleman disease with ganciclovir treatment. Blood 2004; 103:1632-4; PMID:14615380; http://dx.doi.org/10.1182/blood-2003-05-1721.
    • (2004) Blood , vol.103 , pp. 1632-1634
    • Casper, C.1    Nichols, W.G.2    Huang, M.L.3    Corey, L.4    Wald, A.5
  • 35
    • 79959858676 scopus 로고    scopus 로고
    • High-dose zidovudine plus valganciclovir for Kaposi sarcoma herpesvirus-associated multicentric Castleman disease: A pilot study of virus-activated cytotoxic therapy
    • PMID:21487108
    • Uldrick TS, Polizzotto MN, Aleman K, O'Mahony D, Wyvill KM, Wang V, et al. High-dose zidovudine plus valganciclovir for Kaposi sarcoma herpesvirus-associated multicentric Castleman disease: a pilot study of virus-activated cytotoxic therapy. Blood 2011; 117:6977-86; PMID:21487108; http://dx.doi.org/10.1182/blood-2010-11-317610.
    • (2011) Blood , vol.117 , pp. 6977-6986
    • Uldrick, T.S.1    Polizzotto, M.N.2    Aleman, K.3    O'Mahony, D.4    Wyvill, K.M.5    Wang, V.6
  • 36
    • 80055002179 scopus 로고    scopus 로고
    • Targeted drug delivery using immunoconjugates: Principles and applications
    • PMID:21989410
    • Pasquetto MV, Vecchia L, Covini D, Digilio R, Scotti C. Targeted drug delivery using immunoconjugates: principles and applications. J Immunother 2011; 34:611-28; PMID:21989410; http://dx.doi.org/10.1097/CJI.0b013e318234ecf5.
    • (2011) J Immunother , vol.34 , pp. 611-628
    • Pasquetto, M.V.1    Vecchia, L.2    Covini, D.3    Digilio, R.4    Scotti, C.5
  • 37
    • 77955312203 scopus 로고    scopus 로고
    • Antibody-drug conjugates: Targeted drug delivery for cancer
    • PMID:20643572
    • Alley SC, Okeley NM, Senter PD. Antibody-drug conjugates: targeted drug delivery for cancer. Curr Opin Chem Biol 2010; 14:529-37; PMID:20643572; http://dx.doi.org/10.1016/j.cbpa.2010.06.170.
    • (2010) Curr Opin Chem Biol , vol.14 , pp. 529-537
    • Alley, S.C.1    Okeley, N.M.2    Senter, P.D.3
  • 38
    • 80054098573 scopus 로고    scopus 로고
    • Antibody conjugate therapeutics: Challenges and potential
    • PMID:22003066
    • Teicher BA, Chari RVJ. Antibody conjugate therapeutics: challenges and potential. Clin Cancer Res 2011; 17:6389-97; PMID:22003066; http://dx.doi.org/ 10.1158/1078-0432.CCR-11-1417.
    • (2011) Clin Cancer Res , vol.17 , pp. 6389-6397
    • Teicher, B.A.1    Chari, R.V.J.2
  • 39
    • 79952687471 scopus 로고    scopus 로고
    • Cancer radioimmunotherapy
    • PMID:21395378
    • Sharkey RM, Goldenberg DM. Cancer radioimmunotherapy. Immunotherapy 2011; 3:349-70; PMID:21395378; http://dx.doi.org/10.2217/imt.10.114.
    • (2011) Immunotherapy , vol.3 , pp. 349-370
    • Sharkey, R.M.1    Goldenberg, D.M.2
  • 40
    • 80054092984 scopus 로고    scopus 로고
    • Antibody-radionuclide conjugates for cancer therapy: Historical considerations and new trends
    • PMID:22003068
    • Steiner M, Neri D. Antibody-radionuclide conjugates for cancer therapy: historical considerations and new trends. Clin Cancer Res 2011; 17:6406-16; PMID:22003068; http://dx.doi.org/10.1158/1078-0432.CCR-11-0483.
    • (2011) Clin Cancer Res , vol.17 , pp. 6406-6416
    • Steiner, M.1    Neri, D.2
  • 41
    • 34047136785 scopus 로고    scopus 로고
    • Immunotoxin treatment of cancer
    • PMID:17059365
    • Pastan I, Hassan R, FitzGerald DJ, Kreitman RJ. Immunotoxin treatment of cancer. Annu Rev Med 2007; 58:221-37; PMID:17059365; http://dx.doi.org/10.1146/ annurev.med.58.070605.115320.
    • (2007) Annu Rev Med , vol.58 , pp. 221-237
    • Pastan, I.1    Hassan, R.2    FitzGerald, D.J.3    Kreitman, R.J.4
  • 42
    • 79958187876 scopus 로고    scopus 로고
    • Therapeutic potential of anticancer immunotoxins
    • PMID:21511052
    • Choudhary S, Mathew M, Verma RS. Therapeutic potential of anticancer immunotoxins. Drug Discov Today 2011; 16:495-503; PMID:21511052; http://dx.doi.org/10.1016/j.drudis.2011.04.003.
    • (2011) Drug Discov Today , vol.16 , pp. 495-503
    • Choudhary, S.1    Mathew, M.2    Verma, R.S.3
  • 43
    • 79954434429 scopus 로고    scopus 로고
    • Targeted cytotoxic therapy: Adapting a rapidly progressing anticancer paradigm for depletion of persistent HIV-infected cell reservoirs
    • PMID:21242898
    • Berger EA. Targeted cytotoxic therapy: adapting a rapidly progressing anticancer paradigm for depletion of persistent HIV-infected cell reservoirs. Curr Opin HIV AIDS 2011; 6:80-5; PMID:21242898; http://dx.doi.org/10.1097/COH. 0b013e3283412515.
    • (2011) Curr Opin HIV AIDS , vol.6 , pp. 80-85
    • Berger, E.A.1
  • 44
    • 33748906061 scopus 로고    scopus 로고
    • Elimination of HIV-1 infection by treatment with a doxorubicin-conjugated anti-envelope antibody
    • PMID:16988511
    • Johansson S, Goldenberg DM, Griffiths GL, Wahren B, Hinkula J. Elimination of HIV-1 infection by treatment with a doxorubicin-conjugated anti-envelope antibody. AIDS 2006; 20:1911-5; PMID:16988511; http://dx.doi.org/10.1097/01.aids.0000247111.58961.60.
    • (2006) AIDS , vol.20 , pp. 1911-1915
    • Johansson, S.1    Goldenberg, D.M.2    Griffiths, G.L.3    Wahren, B.4    Hinkula, J.5
  • 45
    • 58849115567 scopus 로고    scopus 로고
    • Radioimmunotherapy of infectious diseases
    • PMID:19187806
    • Dadachova E, Casadevall A. Radioimmunotherapy of infectious diseases. Semin Nucl Med 2009; 39:146-53; PMID:19187806; http://dx.doi.org/10.1053/j. semnuclmed. 2008.10.007.
    • (2009) Semin Nucl Med , vol.39 , pp. 146-153
    • Dadachova, E.1    Casadevall, A.2
  • 46
    • 0025971809 scopus 로고
    • Antiviral immunotoxins: Antibody- Mediated delivery of gelonin inhibits Pichinde virus replication in vitro
    • PMID:1650165
    • Barnett BB, Burns NJ, 3rd, Park KJ, Dawson MI, Kende M, Sidwell RW. Antiviral immunotoxins: antibody- mediated delivery of gelonin inhibits Pichinde virus replication in vitro. Antiviral Res 1991; 15:125-38; PMID:1650165; http://dx.doi.org/10.1016/0166-3542(91)90030-U.
    • (1991) Antiviral Res , vol.15 , pp. 125-138
    • Barnett, B.B.1    Burns III, N.J.2    Park, K.J.3    Dawson, M.I.4    Kende, M.5    Sidwell, R.W.6
  • 47
    • 0029123846 scopus 로고
    • Selective cytotoxicity towards cytomegalovirus-infected cells by immunotoxins consisting of gelonin linked to anti-cytomegalovirus antibody
    • PMID:8585763
    • Barnett BB, Smee DF, Malek SM, Sidwell RW. Selective cytotoxicity towards cytomegalovirus-infected cells by immunotoxins consisting of gelonin linked to anti-cytomegalovirus antibody. Antiviral Res 1995; 28:93-100; PMID:8585763; http://dx.doi.org/10.1016/0166-3542(95)00034-J.
    • (1995) Antiviral Res , vol.28 , pp. 93-100
    • Barnett, B.B.1    Smee, D.F.2    Malek, S.M.3    Sidwell, R.W.4
  • 48
    • 0030050736 scopus 로고    scopus 로고
    • Selective cytotoxicity of ricin A chain immunotoxins towards murine cytomegalovirus-infected cells
    • PMID:8834901
    • Barnett BB, Smee DF, Malek SM, Sidwell RW. Selective cytotoxicity of ricin A chain immunotoxins towards murine cytomegalovirus-infected cells. Antimicrob Agents Chemother 1996; 40:470-2; PMID:8834901.
    • (1996) Antimicrob Agents Chemother , vol.40 , pp. 470-472
    • Barnett, B.B.1    Smee, D.F.2    Malek, S.M.3    Sidwell, R.W.4
  • 49
    • 77954685640 scopus 로고    scopus 로고
    • Immunotoxin complementation of HAART to deplete persisting HIV-infected cell reservoirs
    • PMID:20548940
    • Berger EA, Pastan I. Immunotoxin complementation of HAART to deplete persisting HIV-infected cell reservoirs. PLoS Pathog 2010; 6:1000803; PMID:20548940; http://dx.doi.org/10.1371/journal.ppat.1000803.
    • (2010) PLoS Pathog , vol.6 , pp. 1000803
    • Berger, E.A.1    Pastan, I.2
  • 50
    • 77649270721 scopus 로고    scopus 로고
    • A novel composite immunotoxin that suppresses rabies virus production by the infected cells
    • PMID:19932697
    • Mareeva T, Wanjalla C, Schnell MJ, Sykulev Y. A novel composite immunotoxin that suppresses rabies virus production by the infected cells. J Immunol Methods 2010; 353:78-86; PMID:19932697; http://dx.doi.org/10.1016/j.jim. 2009.11.010.
    • (2010) J Immunol Methods , vol.353 , pp. 78-86
    • Mareeva, T.1    Wanjalla, C.2    Schnell, M.J.3    Sykulev, Y.4
  • 51
    • 77649197259 scopus 로고    scopus 로고
    • Early events in Kaposi?s sarcoma-associated herpesvirus infection of target cells
    • PMID:19923183
    • Chandran B. Early events in Kaposi?s sarcoma-associated herpesvirus infection of target cells. J Virol 2010; 84:2188-99; PMID:19923183; http://dx.doi.org/10.1128/JVI.01334-09.
    • (2010) J Virol , vol.84 , pp. 2188-2199
    • Chandran, B.1
  • 52
    • 0032530548 scopus 로고    scopus 로고
    • Human herpesvirus-8 ORF K8.1 gene encodes immunogenic glycoproteins generated by spliced transcripts
    • PMID:9740785
    • Chandran B, Bloomer C, Chan SR, Zhu LJ, Goldstein E, Horvat R. Human herpesvirus-8 ORF K8.1 gene encodes immunogenic glycoproteins generated by spliced transcripts. Virology 1998; 249:140-9; PMID:9740785; http://dx.doi.org/10.1006/viro.1998.9316.
    • (1998) Virology , vol.249 , pp. 140-149
    • Chandran, B.1    Bloomer, C.2    Chan, S.R.3    Zhu, L.J.4    Goldstein, E.5    Horvat, R.6
  • 53
    • 0032923621 scopus 로고    scopus 로고
    • Identification and characterization of Kaposi?s sarcoma-associated herpesvirus K8.1 virion glycoprotein
    • PMID:9882339
    • Li MT, MacKey J, Czajak SC, Desrosiers RC, Lackner AA, Jung JU. Identification and characterization of Kaposi?s sarcoma-associated herpesvirus K8.1 virion glycoprotein. J Virol 1999; 73:1341-9; PMID:9882339.
    • (1999) J Virol , vol.73 , pp. 1341-1349
    • Li, M.T.1    MacKey, J.2    Czajak, S.C.3    Desrosiers, R.C.4    Lackner, A.A.5    Jung, J.U.6
  • 54
    • 0033837397 scopus 로고    scopus 로고
    • Human herpesvirus 8 glycoprotein K8.1: Expression, post-translational modification and localization analyzed by monoclonal antibody
    • PMID:10942093
    • Wu LJ, Renne R, Ganem D, Forghani B. Human herpesvirus 8 glycoprotein K8.1: expression, post-translational modification and localization analyzed by monoclonal antibody. J Clin Virol 2000; 17:127-36; PMID:10942093; http://dx.doi.org/10.1016/S1386-6532(00)00085-8.
    • (2000) J Clin Virol , vol.17 , pp. 127-136
    • Wu, L.J.1    Renne, R.2    Ganem, D.3    Forghani, B.4
  • 55
    • 0033568369 scopus 로고    scopus 로고
    • Characterization of human herpesvirus-8 K8.1A/B glycoproteins by monoclonal antibodies
    • PMID:10489357
    • Zhu LJ, Puri V, Chandran B. Characterization of human herpesvirus-8 K8.1A/B glycoproteins by monoclonal antibodies. Virology 1999; 262:237-49; PMID:10489357; http://dx.doi.org/10.1006/viro.1999.9900.
    • (1999) Virology , vol.262 , pp. 237-249
    • Zhu, L.J.1    Puri, V.2    Chandran, B.3
  • 56
    • 11144222534 scopus 로고    scopus 로고
    • Virion proteins of Kaposi?s sarcoma-associated herpesvirus
    • PMID:15613308
    • Zhu FX, Chong JM, Wu LJ, Yuan Y. Virion proteins of Kaposi?s sarcoma-associated herpesvirus. J Virol 2005; 79:800-11; PMID:15613308; http://dx.doi.org/10.1128/JVI.79.2.800-11.2005.
    • (2005) J Virol , vol.79 , pp. 800-811
    • Zhu, F.X.1    Chong, J.M.2    Wu, L.J.3    Yuan, Y.4
  • 57
    • 0034902748 scopus 로고    scopus 로고
    • Human herpesvirus 8 envelope glycoprotein K8.1A interaction with the target cells involves heparan sulfate
    • PMID:11462024
    • Wang FZ, Akula SM, Pramod NP, Zeng L, Chandran B. Human herpesvirus 8 envelope glycoprotein K8.1A interaction with the target cells involves heparan sulfate. J Virol 2001; 75:7517-27; PMID:11462024; http://dx.doi.org/10.1128/JVI. 75.16.7517-27.2001.
    • (2001) J Virol , vol.75 , pp. 7517-7527
    • Wang, F.Z.1    Akula, S.M.2    Pramod, N.P.3    Zeng, L.4    Chandran, B.5
  • 58
    • 0035159830 scopus 로고    scopus 로고
    • Cell surface heparan sulfate is a receptor for human herpesvirus 8 and interacts with envelope glycoprotein K8.1
    • PMID:11689640
    • Birkmann A, Mahr K, Ensser A, Yaubolu S, Titgemeyer F, Fleckenstein B, et al. Cell surface heparan sulfate is a receptor for human herpesvirus 8 and interacts with envelope glycoprotein K8.1. J Virol 2001; 75:11583-93; PMID:11689640; http://dx.doi.org/10.1128/JVI.75.23.11583-93.2001.
    • (2001) J Virol , vol.75 , pp. 11583-11593
    • Birkmann, A.1    Mahr, K.2    Ensser, A.3    Yaubolu, S.4    Titgemeyer, F.5    Fleckenstein, B.6
  • 59
    • 0034177734 scopus 로고    scopus 로고
    • Identifying human herpesvirus 8 infection: Performance characteristics of serologic assays
    • PMID:10836758.
    • Engels EA, Whitby D, Goebel PB, Stossel A, Waters D, Pintus A, et al. Identifying human herpesvirus 8 infection: performance characteristics of serologic assays. J Acquir Immune Defic Syndr 2000; 23:346-54; PMID:10836758.
    • (2000) J Acquir Immune Defic Syndr , vol.23 , pp. 346-354
    • Engels, E.A.1    Whitby, D.2    Goebel, P.B.3    Stossel, A.4    Waters, D.5    Pintus, A.6
  • 60
    • 0033056695 scopus 로고    scopus 로고
    • Identification and rapid quantification of early- And late-lytic human herpesvirus 8 infection in single cells by flow cytometric analysis: Characterization of antiherpesvirus agents
    • PMID:10364341
    • Zoeteweij JP, Eyes ST, Orenstein JM, Kawamura T, Wu LJ, Chandran B, et al. Identification and rapid quantification of early- and late-lytic human herpesvirus 8 infection in single cells by flow cytometric analysis: characterization of antiherpesvirus agents. J Virol 1999; 73:5894-902; PMID:10364341.
    • (1999) J Virol , vol.73 , pp. 5894-5902
    • Zoeteweij, J.P.1    Eyes, S.T.2    Orenstein, J.M.3    Kawamura, T.4    Wu, L.J.5    Chandran, B.6
  • 61
    • 1642416839 scopus 로고    scopus 로고
    • Recombinant immunotoxins in the treatment of cancer
    • Lo BKC, Ed. Totowa, NJ: Humana Press Inc.
    • Pastan I, Beers R, Bera TK. Recombinant immunotoxins in the treatment of cancer. In: Lo BKC, Ed. Meth Molec Biol. Totowa, NJ: Humana Press Inc. 2003; 503-18.
    • (2003) Meth Molec Biol , pp. 503-518
    • Pastan, I.1    Beers, R.2    Bera, T.K.3
  • 62
    • 3142604959 scopus 로고    scopus 로고
    • Use of the red fluorescent protein as a marker of Kaposi?s sarcoma-associated herpesvirus lytic gene expression
    • PMID:15246263
    • Vieira J, O'Hearn PM. Use of the red fluorescent protein as a marker of Kaposi?s sarcoma-associated herpesvirus lytic gene expression. Virology 2004; 325:225-40; PMID:15246263; http://dx.doi.org/10.1016/j.virol.2004.03.049.
    • (2004) Virology , vol.325 , pp. 225-240
    • Vieira, J.1    O'Hearn, P.M.2
  • 63
    • 0002494823 scopus 로고    scopus 로고
    • A water-soluble tetrazolium salt useful for colorimetric cell viability assay
    • Tominaga H, Ishiyama M, Ohseto F, Sasamoto K, Hamamoto T, Suzuki K, et al. A water-soluble tetrazolium salt useful for colorimetric cell viability assay. Anal Commun 1999; 36:47-50; http://dx.doi.org/10.1039/a809656b.
    • (1999) Anal Commun , vol.36 , pp. 47-50
    • Tominaga, H.1    Ishiyama, M.2    Ohseto, F.3    Sasamoto, K.4    Hamamoto, T.5    Suzuki, K.6
  • 64
    • 0030980240 scopus 로고    scopus 로고
    • Sensitivity of Kaposi?s sarcoma- Associated herpesvirus replication to antiviral drugs. Implications for potential therapy
    • PMID:9151779
    • Kedes DH, Ganem D. Sensitivity of Kaposi?s sarcoma- associated herpesvirus replication to antiviral drugs. Implications for potential therapy. J Clin Invest 1997; 99:2082-6; PMID:9151779; http://dx.doi.org/10.1172/ JCI119380.
    • (1997) J Clin Invest , vol.99 , pp. 2082-2086
    • Kedes, D.H.1    Ganem, D.2
  • 65
    • 0030767409 scopus 로고    scopus 로고
    • In vitro antiviral drug sensitivity of the Kaposi?s sarcoma-associated herpesvirus
    • PMID:9302441
    • Medveczky MM, Horvath E, Lund T, Medveczky PG. In vitro antiviral drug sensitivity of the Kaposi?s sarcoma-associated herpesvirus. AIDS 1997; 11:1327-32; PMID:9302441; http://dx.doi.org/10.1097/00002030-199711000-00006.
    • (1997) AIDS , vol.11 , pp. 1327-1332
    • Medveczky, M.M.1    Horvath, E.2    Lund, T.3    Medveczky, P.G.4
  • 66
    • 10044265682 scopus 로고    scopus 로고
    • Dissection of the Kaposi?s sarcoma-associated herpesvirus gene expression program by using the viral DNA replication inhibitor cidofovir
    • PMID:15564474
    • Lu M, Suen J, Frias C, Pfeiffer R, Tsai MH, Chuang E, et al. Dissection of the Kaposi?s sarcoma-associated herpesvirus gene expression program by using the viral DNA replication inhibitor cidofovir. J Virol 2004; 78:13637-52; PMID:15564474; http://dx.doi.org/10.1128/JVI.78.24.13637-52.2004.
    • (2004) J Virol , vol.78 , pp. 13637-13652
    • Lu, M.1    Suen, J.2    Frias, C.3    Pfeiffer, R.4    Tsai, M.H.5    Chuang, E.6
  • 67
    • 46349104673 scopus 로고    scopus 로고
    • Valganciclovir for suppression of human herpesvirus-8 replication: A randomized, double- Blind, placebo-controlled, crossover trial
    • PMID:18491970
    • Casper C, Krantz EM, Corey L, Kuntz SR, Wang J, Selke S, et al. Valganciclovir for suppression of human herpesvirus-8 replication: a randomized, double- blind, placebo-controlled, crossover trial. J Infect Dis 2008; 198:23-30; PMID:18491970; http://dx.doi.org/10.1086/588820.
    • (2008) J Infect Dis , vol.198 , pp. 23-30
    • Casper, C.1    Krantz, E.M.2    Corey, L.3    Kuntz, S.R.4    Wang, J.5    Selke, S.6
  • 68
    • 80051577902 scopus 로고    scopus 로고
    • Treatment with valacyclovir, famciclovir or antiretrovirals reduces human herpes-virus- 8 replication in HIV-1 seropositive men
    • PMID:21837785
    • Cattamanchi A, Saracino M, Selke S, Huang ML, Magaret A, Celum C, et al. Treatment with valacyclovir, famciclovir or antiretrovirals reduces human herpes-virus- 8 replication in HIV-1 seropositive men. J Med Virol 2011; 83:1696-703; PMID:21837785; http://dx.doi.org/10.1002/jmv.22194.
    • (2011) J Med Virol , vol.83 , pp. 1696-1703
    • Cattamanchi, A.1    Saracino, M.2    Selke, S.3    Huang, M.L.4    Magaret, A.5    Celum, C.6
  • 69
    • 0025852258 scopus 로고
    • Anti-HIV activity of CD4-Pseudomonas exotoxin on infected primary human lymphocytes and monocyte/macrophages
    • PMID:2010626
    • Ashorn P, Englund G, Martin MA, Moss B, Berger EA. Anti-HIV activity of CD4-Pseudomonas exotoxin on infected primary human lymphocytes and monocyte/macrophages. J Infect Dis 1991; 163:703-9; PMID:2010626; http://dx.doi.org/10.1093/infdis/163.4.703.
    • (1991) J Infect Dis , vol.163 , pp. 703-709
    • Ashorn, P.1    Englund, G.2    Martin, M.A.3    Moss, B.4    Berger, E.A.5
  • 70
    • 33750427894 scopus 로고    scopus 로고
    • Anti-HIV-1 immunotoxin 3B3(Fv)-PE38: Enhanced potency against clinical isolates in human PBMCs and macrophages and negligible hepatotoxicity in macaques
    • PMID:16923920
    • Kennedy PE, Bera TK, Wang QC, Gallo M, Wagner W, Lewis MG, et al. Anti-HIV-1 immunotoxin 3B3(Fv)-PE38: enhanced potency against clinical isolates in human PBMCs and macrophages and negligible hepatotoxicity in macaques. J Leukoc Biol 2006; 80:1175-82; PMID:16923920; http://dx.doi.org/10.1189/jlb. 0306139.
    • (2006) J Leukoc Biol , vol.80 , pp. 1175-1182
    • Kennedy, P.E.1    Bera, T.K.2    Wang, Q.C.3    Gallo, M.4    Wagner, W.5    Lewis, M.G.6
  • 71
    • 0025348219 scopus 로고
    • Replication of HIV-1 in primary monocyte cultures
    • PMID:2183468
    • Potts BJ, Maury W, Martin MA. Replication of HIV-1 in primary monocyte cultures. Virology 1990; 175:465-76; PMID:2183468; http://dx.doi.org/10.1016/ 0042-6822(90)90431-P.
    • (1990) Virology , vol.175 , pp. 465-476
    • Potts, B.J.1    Maury, W.2    Martin, M.A.3
  • 72
    • 34548858453 scopus 로고    scopus 로고
    • Phase I study of SS1P, a recombinant anti-mesothelin immunotoxin given as a bolus I.V. infusion to patients with mesothelin-expressing mesothelioma, ovarian and pancreatic cancers
    • PMID:17785569
    • Hassan R, Bullock S, Premkumar A, Kreitman RJ, Kindler H, Willingham MC, et al. Phase I study of SS1P, a recombinant anti-mesothelin immunotoxin given as a bolus I.V. infusion to patients with mesothelin-expressing mesothelioma, ovarian and pancreatic cancers. Clin Cancer Res 2007; 13:5144-9; PMID:17785569; http://dx.doi.org/10.1158/1078-0432.CCR-07-0869.
    • (2007) Clin Cancer Res , vol.13 , pp. 5144-5149
    • Hassan, R.1    Bullock, S.2    Premkumar, A.3    Kreitman, R.J.4    Kindler, H.5    Willingham, M.C.6
  • 73
    • 84925567311 scopus 로고    scopus 로고
    • Phase I/II trial of anti-CD22 recombinant immunotoxin moxetumomab pasudotox (CAT-8015 or HA22) in patients with hairy cell leukemia
    • In press
    • Kreitman RJ, Tallman MS, Robak T, Coutre S, Wilson WH, Stetler-Stevenson M, et al. Phase I/II trial of anti-CD22 recombinant immunotoxin moxetumomab pasudotox (CAT-8015 or HA22) in patients with hairy cell leukemia. J Clin Oncol; In press.
    • J Clin Oncol
    • Kreitman, R.J.1    Tallman, M.S.2    Robak, T.3    Coutre, S.4    Wilson, W.H.5    Stetler-Stevenson, M.6
  • 74
    • 27244448693 scopus 로고    scopus 로고
    • Phase I trial of recombinant immunotoxin RFB4(dsFv)-PE38 (BL22) in patients with B-cell malignancies
    • PMID:16061911
    • Kreitman RJ, Squires DR, Stetler-Stevenson M, Noel P, FitzGerald DJP, Wilson WH, et al. Phase I trial of recombinant immunotoxin RFB4(dsFv)-PE38 (BL22) in patients with B-cell malignancies. J Clin Oncol 2005; 23:6719-29; PMID:16061911; http://dx.doi.org/10.1200/JCO.2005.11.437.
    • (2005) J Clin Oncol , vol.23 , pp. 6719-6729
    • Kreitman, R.J.1    Squires, D.R.2    Stetler-Stevenson, M.3    Noel, P.4    FitzGerald, D.J.P.5    Wilson, W.H.6
  • 75
    • 80054118081 scopus 로고    scopus 로고
    • Antibody fusion proteins: Anti-CD22 recombinant immunotoxin moxetumomab pasudotox
    • PMID:22003067
    • Kreitman RJ, Pastan I. Antibody fusion proteins: anti-CD22 recombinant immunotoxin moxetumomab pasudotox. Clin Cancer Res 2011; 17:6398-405; PMID:22003067; http://dx.doi.org/10.1158/1078-0432.CCR-11-0487.
    • (2011) Clin Cancer Res , vol.17 , pp. 6398-6405
    • Kreitman, R.J.1    Pastan, I.2
  • 76
    • 2542477008 scopus 로고    scopus 로고
    • Failure of cidofovir in HIV-associated multicentric Castleman disease
    • PMID:15155471
    • Berezne A, Agbalika F, Oksenhendler E. Failure of cidofovir in HIV-associated multicentric Castleman disease. Blood 2004; 103:4368-9; PMID:15155471; http://dx.doi.org/10.1182/blood-2004-01-0158.
    • (2004) Blood , vol.103 , pp. 4368-4369
    • Berezne, A.1    Agbalika, F.2    Oksenhendler, E.3
  • 77
    • 79953871010 scopus 로고    scopus 로고
    • An immunotoxin targeting the gH glycoprotein of KSHV for selective killing of cells in the lytic phase of infection
    • PMID:21440007
    • Cai Y, Berger EA. An immunotoxin targeting the gH glycoprotein of KSHV for selective killing of cells in the lytic phase of infection. Antiviral Res 2011; 90:143-50; PMID:21440007; http://dx.doi.org/10.1016/j.antiviral. 2011.03.175.
    • (2011) Antiviral Res , vol.90 , pp. 143-150
    • Cai, Y.1    Berger, E.A.2
  • 78
    • 0030273872 scopus 로고    scopus 로고
    • Combination of antiviral immunotoxin and ganciclovir or cidofovir for the treatment of murine cytomegalovirus infections
    • PMID:8955511
    • Smee DF, Sidwell RW, Barnett BB. Combination of antiviral immunotoxin and ganciclovir or cidofovir for the treatment of murine cytomegalovirus infections. Antiviral Res 1996; 32:165-71; PMID:8955511; http://dx.doi.org/10. 1016/S0166-3542(95)00986-8.
    • (1996) Antiviral Res , vol.32 , pp. 165-171
    • Smee, D.F.1    Sidwell, R.W.2    Barnett, B.B.3
  • 79
    • 0025225451 scopus 로고
    • Elimination of infectious human immunodeficiency virus from human T-cell cultures by synergistic action of CD4-Pseudomonas exotoxin and reverse transcriptase inhibitors
    • PMID:1701055
    • Ashorn P, Moss B, Weinstein JN, Chaudhary VK, FitzGerald DJ, Pastan I, et al. Elimination of infectious human immunodeficiency virus from human T-cell cultures by synergistic action of CD4-Pseudomonas exotoxin and reverse transcriptase inhibitors. Proc Natl Acad Sci USA 1990; 87:8889-93; PMID:1701055; http://dx.doi.org/10.1073/pnas.87.22.8889.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 8889-8893
    • Ashorn, P.1    Moss, B.2    Weinstein, J.N.3    Chaudhary, V.K.4    FitzGerald, D.J.5    Pastan, I.6
  • 80
    • 0025119720 scopus 로고
    • CD4-Pseudomonas exotoxin conjugates delay but do not fully inhibit human immunodeficiency virus replication in lymphocytes in vitro
    • PMID:2243139
    • Tsubota H, Winkler G, Meade HM, Jakubowski A, Thomas DW, Letvin NL. CD4-Pseudomonas exotoxin conjugates delay but do not fully inhibit human immunodeficiency virus replication in lymphocytes in vitro. J Clin Invest 1990; 86:1684-9; PMID:2243139; http://dx.doi.org/10.1172/JCI114892.
    • (1990) J Clin Invest , vol.86 , pp. 1684-1689
    • Tsubota, H.1    Winkler, G.2    Meade, H.M.3    Jakubowski, A.4    Thomas, D.W.5    Letvin, N.L.6
  • 81
    • 0034081778 scopus 로고    scopus 로고
    • Chimeric toxins targeted to the human immunodeficiency virus type 1 envelope glycoprotein augment the in vivo activity of combination antiretroviral therapy in thy/liv-SCID-Hu mice
    • PMID:10720513
    • Goldstein H, Pettoello-Mantovani M, Bera TK, Pastan IH, Berger EA. Chimeric toxins targeted to the human immunodeficiency virus type 1 envelope glycoprotein augment the in vivo activity of combination antiretroviral therapy in thy/liv-SCID-Hu mice. J Infect Dis 2000; 181:921-6; PMID:10720513; http://dx.doi.org/10.1086/315351.
    • (2000) J Infect Dis , vol.181 , pp. 921-926
    • Goldstein, H.1    Pettoello-Mantovani, M.2    Bera, T.K.3    Pastan, I.H.4    Berger, E.A.5
  • 82
    • 70350645181 scopus 로고    scopus 로고
    • Denileukin diftitox: A novel immunotoxin
    • PMID:19817678
    • Manoukian G, Hagemeister F. Denileukin diftitox: a novel immunotoxin. Expert Opin Biol Ther 2009; 9:1445-51; PMID:19817678; http://dx.doi.org/10.1517/ 14712590903348135.
    • (2009) Expert Opin Biol Ther , vol.9 , pp. 1445-1451
    • Manoukian, G.1    Hagemeister, F.2
  • 83
    • 79956215035 scopus 로고    scopus 로고
    • Cytotoxic therapy with diphtheria toxin fusion proteins
    • Woo JH, Frankel A, Neville DM. Cytotoxic therapy with diphtheria toxin fusion proteins. Drugs Future 2010; 35:823-31; http://dx.doi.org/10.1358/dof. 2010.035.010.1534010.
    • (2010) Drugs Future , vol.35 , pp. 823-831
    • Woo, J.H.1    Frankel, A.2    Neville, D.M.3
  • 84
    • 80054113954 scopus 로고    scopus 로고
    • Antibody-drug conjugates of calicheamicin derivative: Gemtuzumab ozogamicin and inotuzumab ozogamicin
    • PMID:22003069
    • Ricart AD. Antibody-drug conjugates of calicheamicin derivative: gemtuzumab ozogamicin and inotuzumab ozogamicin. Clin Cancer Res 2011; 17:6417-27; PMID:22003069; http://dx.doi.org/10.1158/1078-0432.CCR-11-0486.
    • (2011) Clin Cancer Res , vol.17 , pp. 6417-6427
    • Ricart, A.D.1
  • 85
    • 70350150330 scopus 로고    scopus 로고
    • Improved immunotoxins with novel functional elements
    • PMID:19689340
    • Hetzel C, Bachran C, Tur MK, Fuchs H, Stöcker M. Improved immunotoxins with novel functional elements. Curr Pharm Des 2009; 15:2700-11; PMID:19689340; http://dx.doi.org/10.2174/138161209788923930.
    • (2009) Curr Pharm Des , vol.15 , pp. 2700-2711
    • Hetzel, C.1    Bachran, C.2    Tur, M.K.3    Fuchs, H.4    Stöcker, M.5
  • 86
    • 81555214408 scopus 로고    scopus 로고
    • A guide to taming a toxin - Recombinant immunotoxins constructed from Pseudomonas exotoxin A for the treatment of cancer
    • PMID:21585657
    • Weldon JE, Pastan I. A guide to taming a toxin - recombinant immunotoxins constructed from Pseudomonas exotoxin A for the treatment of cancer. FEBS J 2011; 278:4683-700; PMID:21585657; http://dx.doi.org/10.1111/j.1742-4658.2011. 08182.x.
    • (2011) FEBS J , vol.278 , pp. 4683-4700
    • Weldon, J.E.1    Pastan, I.2
  • 87
    • 0032213076 scopus 로고    scopus 로고
    • Comparison of recombinant immunotoxins against LeY antigen expressing tumor cells: Influence of affinity, size and stability
    • PMID:9815167
    • Bera TK, Pastan I. Comparison of recombinant immunotoxins against LeY antigen expressing tumor cells: influence of affinity, size and stability. Bioconjug Chem 1998; 9:736-43; PMID:9815167; http://dx.doi.org/10.1021/ bc980028o.
    • (1998) Bioconjug Chem , vol.9 , pp. 736-743
    • Bera, T.K.1    Pastan, I.2
  • 88
    • 77953653678 scopus 로고    scopus 로고
    • "Inclonals": IgGs and IgG-enzyme fusion proteins produced in an E. coli expression-refolding system
    • PMID:20065645
    • Hakim R, Benhar I. ?Inclonals?: IgGs and IgG-enzyme fusion proteins produced in an E. coli expression-refolding system. MAbs 2009; 1:281-7; PMID:20065645; http://dx.doi.org/10.4161/mabs.1.3.8492.
    • (2009) MAbs , vol.1 , pp. 281-287
    • Hakim, R.1    Benhar, I.2
  • 89
    • 79955007493 scopus 로고    scopus 로고
    • Recombinant immunotoxin against B-cell malignancies with no immunogenicity in mice by removal of B-cell epitopes
    • PMID:21436054
    • Onda M, Beers R, Xiang LM, Lee B, Weldon JE, Kreitman RJ, et al. Recombinant immunotoxin against B-cell malignancies with no immunogenicity in mice by removal of B-cell epitopes. Proc Natl Acad Sci USA 2011; 108:5742-7; PMID:21436054; http://dx.doi.org/10.1073/pnas.1102746108.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 5742-5747
    • Onda, M.1    Beers, R.2    Xiang, L.M.3    Lee, B.4    Weldon, J.E.5    Kreitman, R.J.6
  • 90
    • 67650678448 scopus 로고    scopus 로고
    • Humanized immunotoxins: A new generation of immunotoxins for targeted cancer therapy
    • PMID:19459847
    • Mathew M, Verma RS. Humanized immunotoxins: a new generation of immunotoxins for targeted cancer therapy. Cancer Sci 2009; 100:1359-65; PMID:19459847; http://dx.doi.org/10.1111/j.1349-7006.2009.01192.x.
    • (2009) Cancer Sci , vol.100 , pp. 1359-1365
    • Mathew, M.1    Verma, R.S.2
  • 91
    • 79955104910 scopus 로고    scopus 로고
    • Human toxin-based recombinant immunotoxins/chimeric proteins as a drug delivery system for targeted treatment of human diseases
    • PMID:21453191
    • Lorberboum-Galski H. Human toxin-based recombinant immunotoxins/chimeric proteins as a drug delivery system for targeted treatment of human diseases. Expert Opin Drug Deliv 2011; 8:605-21; PMID:21453191; http://dx.doi.org/10.1517/ 17425247.2011.566269.
    • (2011) Expert Opin Drug Deliv , vol.8 , pp. 605-621
    • Lorberboum-Galski, H.1
  • 92
    • 0031813707 scopus 로고    scopus 로고
    • Specific killing of HIV-infected lymphocytes by a recombinant immunotoxin directed against the HIV-1 envelope glycoprotein
    • PMID:10780881
    • Bera TK, Kennedy PE, Berger EA, Barbas CFI, 3rd, Pastan I. Specific killing of HIV-infected lymphocytes by a recombinant immunotoxin directed against the HIV-1 envelope glycoprotein. Mol Med 1998; 4:384-91; PMID:10780881.
    • (1998) Mol Med , vol.4 , pp. 384-391
    • Bera, T.K.1    Kennedy, P.E.2    Berger, E.A.3    Barbas III, C.F.I.4    Pastan, I.5
  • 93
    • 0023449908 scopus 로고
    • Exotoxin A of Pseudomonas aeruginosa: Substitution of glutamic acid 553 with aspartic acid drastically reduces toxicity and enzymatic activity
    • PMID:2889718
    • Douglas CM, Collier RJ. Exotoxin A of Pseudomonas aeruginosa: substitution of glutamic acid 553 with aspartic acid drastically reduces toxicity and enzymatic activity. J Bacteriol 1987; 169:4967-71; PMID:2889718.
    • (1987) J Bacteriol , vol.169 , pp. 4967-4971
    • Douglas, C.M.1    Collier, R.J.2
  • 94
    • 0035954624 scopus 로고    scopus 로고
    • Efficacy of the anti-CD22 recombinant immunotoxin BL22 in chemotherapy-resistant hairy-cell leukemia
    • PMID:11474661
    • Kreitman RJ, Wilson WH, Bergeron K, Raggio M, Stetler-Stevenson M, FitzGerald DJ, et al. Efficacy of the anti-CD22 recombinant immunotoxin BL22 in chemotherapy-resistant hairy-cell leukemia. N Engl J Med 2001; 345:241-7; PMID:11474661; http://dx.doi.org/10.1056/NEJM200107263450402.
    • (2001) N Engl J Med , vol.345 , pp. 241-247
    • Kreitman, R.J.1    Wilson, W.H.2    Bergeron, K.3    Raggio, M.4    Stetler-Stevenson, M.5    FitzGerald, D.J.6
  • 95
    • 78049274849 scopus 로고    scopus 로고
    • Cell adhesion-dependent membrane trafficking of a binding partner for the ebolavirus glycoprotein is a determinant of viral entry
    • PMID:20817853
    • Dube D, Schornberg KL, Shoemaker CJ, Delos SE, Stantchev TS, Clouse KA, et al. Cell adhesion-dependent membrane trafficking of a binding partner for the ebolavirus glycoprotein is a determinant of viral entry. Proc Natl Acad Sci USA 2010; 107:16637-42; PMID:20817853; http://dx.doi.org/10.1073/pnas.1008509107.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 16637-16642
    • Dube, D.1    Schornberg, K.L.2    Shoemaker, C.J.3    Delos, S.E.4    Stantchev, T.S.5    Clouse, K.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.