-
2
-
-
62249095476
-
The challenge of finding a cure for HIV infection
-
Richman DD, Margolis DM, Delaney M, Greene WC, Hazuda D, et al. (2009) The challenge of finding a cure for HIV infection. Science 323:1304-1307.
-
(2009)
Science
, vol.323
, pp. 1304-1307
-
-
Richman, D.D.1
Margolis, D.M.2
Delaney, M.3
Greene, W.C.4
Hazuda, D.5
-
3
-
-
2642709177
-
Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators
-
Palella FJ Jr, Delaney KM, Moorman AC, Loveless MO, Fuhrer J, et al. (1998) Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators. N Engl J Med 338: 853-860.
-
(1998)
N Engl J Med
, vol.338
, pp. 853-860
-
-
Palella Jr., F.J.1
Delaney, K.M.2
Moorman, A.C.3
Loveless, M.O.4
Fuhrer, J.5
-
4
-
-
15744390082
-
Declining AIDS mortality in Amsterdam: Contributions of declining HIV incidence and effective therapy
-
Smit C, Geskus R, Uitenbroek D, Mulder D, Van Den Hoek A, et al. (2004) Declining AIDS mortality in Amsterdam: contributions of declining HIV incidence and effective therapy. Epidemiology 15: 536-542.
-
(2004)
Epidemiology
, vol.15
, pp. 536-542
-
-
Smit, C.1
Geskus, R.2
Uitenbroek, D.3
Mulder, D.4
Van den Hoek, A.5
-
5
-
-
0034446565
-
The genetic basis of HIV-1 resistance to reverse transcriptase and protease inhibitors
-
Shafer R, Kantor R, Gonzales MJ (2000) The genetic basis of HIV-1 resistance to reverse transcriptase and protease inhibitors. AIDS Rev 2: 211-228.
-
(2000)
AIDS Rev
, vol.2
, pp. 211-228
-
-
Shafer, R.1
Kantor, R.2
Gonzales, M.J.3
-
6
-
-
22544486548
-
HIV protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug resistance surveillance
-
Rhee SY, Fessel WJ, Zolopa AR, Hurley L, Liu T, Taylor J, et al. (2005) HIV protease and reverse transcriptase mutations: correlations with antiretroviral therapy in subtype B isolates and implications for drug resistance surveillance. J Infect Dis 192: 456-465.
-
(2005)
J Infect Dis
, vol.192
, pp. 456-465
-
-
Rhee, S.Y.1
Fessel, W.J.2
Zolopa, A.R.3
Hurley, L.4
Liu, T.5
Taylor, J.6
-
7
-
-
19344373478
-
Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration
-
Kantor R, Katzenstein DA, Efron B, Carvalho AP, Wynhoven B, et al. (2005) Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: results of a global collaboration. PLoS Med 2: e112.
-
(2005)
PLoS Med
, vol.2
-
-
Kantor, R.1
Katzenstein, D.A.2
Efron, B.3
Carvalho, A.P.4
Wynhoven, B.5
-
8
-
-
79952267805
-
Update of the Drug Resistance Mutations in HIV-1: December 2010
-
Johnson VA, Brun-Vézinet F, Clotet B, Günthard HF, Kuritzkes DR, et al. (2010) Update of the Drug Resistance Mutations in HIV-1: December 2010. Top HIV Med 18: 156-163.
-
(2010)
Top HIV Med
, vol.18
, pp. 156-163
-
-
Johnson, V.A.1
Brun-Vézinet, F.2
Clotet, B.3
Günthard, H.F.4
Kuritzkes, D.R.5
-
10
-
-
84879824380
-
-
AIDS Vaccine Advocacy Coalition. Ongoing PrEP trials
-
AIDS Vaccine Advocacy Coalition. Global advocacy for HIV prevention. Ongoing PrEP trials.
-
Global advocacy for HIV prevention.
-
-
-
11
-
-
78649392094
-
Chemoprophylaxis for HIV prevention: New opportunities and new questions
-
Mayer KH, Venkatesh KK (2010) Chemoprophylaxis for HIV prevention: new opportunities and new questions. J Acquir Immune Defic Syndr 55 Suppl 2: S122-127.
-
(2010)
J Acquir Immune Defic Syndr
, vol.55
, Issue.SUPPL. 2
-
-
Mayer, K.H.1
Venkatesh, K.K.2
-
12
-
-
79958087207
-
Achieving safe conception in HIV-discordant couples: The potential role of oral preexposure prophylaxis (PrEP) in the United States
-
Lampe MA, Smith DK, Anderson GJ, Edwards AE, Nesheim SR (2011) Achieving safe conception in HIV-discordant couples: the potential role of oral preexposure prophylaxis (PrEP) in the United States. Am J Obstet Gynecol 204: 488. e1-8.
-
(2011)
Am J Obstet Gynecol
, vol.204
-
-
Lampe, M.A.1
Smith, D.K.2
Anderson, G.J.3
Edwards, A.E.4
Nesheim, S.R.5
-
13
-
-
79957484785
-
Preexposure prophylaxis for HIV prevention
-
Kelesidis T, Landovitz RJ (2011) Preexposure prophylaxis for HIV prevention. Curr HIV/AIDS Rep 8: 94-103.
-
(2011)
Curr HIV/AIDS Rep
, vol.8
, pp. 94-103
-
-
Kelesidis, T.1
Landovitz, R.J.2
-
14
-
-
81855160859
-
Pre-Exposure Prophylaxis and Antiretroviral Resistance: HIV Prevention at a Cost?
-
Hurt CB, Eron JJ Jr, Cohen MS (2011) Pre-Exposure Prophylaxis and Antiretroviral Resistance: HIV Prevention at a Cost? Clin Infect Dis 53: 1265-1270.
-
(2011)
Clin Infect Dis
, vol.53
, pp. 1265-1270
-
-
Hurt, C.B.1
Eron Jr., J.J.2
Cohen, M.S.3
-
15
-
-
71749100912
-
Structural basis for the role of the K65R mutation in HIV-1 reverse transcriptase polymerization, excision antagonism, and tenofovir resistance
-
Das K, Bandwar RP, White KL, Feng JY, Sarafianos SG, et al. (2009) Structural basis for the role of the K65R mutation in HIV-1 reverse transcriptase polymerization, excision antagonism, and tenofovir resistance. J Biol Chem 284: 35092-35100.
-
(2009)
J Biol Chem
, vol.284
, pp. 35092-35100
-
-
Das, K.1
Bandwar, R.P.2
White, K.L.3
Feng, J.Y.4
Sarafianos, S.G.5
-
16
-
-
1442349112
-
Molecular mechanisms of tenofovir resistance conferred by human immunodeficiency virus type 1 reverse transcriptase containing a diserine insertion after residue 69 and multiple thymidine analog-associated mutations
-
White KL, Chen JM, Margot NA, Wrin T, Petropoulos CJ, et al. (2004) Molecular mechanisms of tenofovir resistance conferred by human immunodeficiency virus type 1 reverse transcriptase containing a diserine insertion after residue 69 and multiple thymidine analog-associated mutations. Antimicrob Agents Chemother 48: 992-1003.
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 992-1003
-
-
White, K.L.1
Chen, J.M.2
Margot, N.A.3
Wrin, T.4
Petropoulos, C.J.5
-
17
-
-
81855160859
-
Pre-Exposure Prophylaxis and Antiretroviral Resistance: HIV Prevention at a Cost?
-
Hurt CB, Eron JJ Jr, Cohen MS (2011) Pre-Exposure Prophylaxis and Antiretroviral Resistance: HIV Prevention at a Cost? Clin Infect Dis 53: 1265-1270.
-
(2011)
Clin Infect Dis
, vol.53
, pp. 1265-1270
-
-
Hurt, C.B.1
Eron Jr., J.J.2
Cohen, M.S.3
-
20
-
-
33645099474
-
Unmet challenges in HIV therapy and potential of stampidine
-
Uckun FM (2006) Unmet challenges in HIV therapy and potential of stampidine. Arzneimittelforschung 56: 117-120.
-
(2006)
Arzneimittelforschung
, vol.56
, pp. 117-120
-
-
Uckun, F.M.1
-
22
-
-
34848886926
-
Intracellular nucleoside trophosphate concentrations in HIV-infected patients on dual nucleoside reverse transcriptase inhibitor therapy
-
Moore JD, Acosta EP, Johnson VA, Bassett R, Eron JJ, et al. (2007) Intracellular nucleoside trophosphate concentrations in HIV-infected patients on dual nucleoside reverse transcriptase inhibitor therapy. Antivir Ther 12: 981-986.
-
(2007)
Antivir Ther
, vol.12
, pp. 981-986
-
-
Moore, J.D.1
Acosta, E.P.2
Johnson, V.A.3
Bassett, R.4
Eron, J.J.5
-
23
-
-
0032542075
-
Enhancing effects of a mono-bromo substitution at the para position of the phenyl moiety on the metabolism and anti-HIV activity of d4T-phenyl methoxyalaninyl phosphate derivatives
-
Venkatachalam TK, Tai HL, Vig R, Chen CL, Jan ST, Uckun FM (1998) Enhancing effects of a mono-bromo substitution at the para position of the phenyl moiety on the metabolism and anti-HIV activity of d4T-phenyl methoxyalaninyl phosphate derivatives. Bioorg Med Chem Lett 8: 3121-3126.
-
(1998)
Bioorg Med Chem Lett
, vol.8
, pp. 3121-3126
-
-
Venkatachalam, T.K.1
Tai, H.L.2
Vig, R.3
Chen, C.L.4
Jan, S.T.5
Uckun, F.M.6
-
24
-
-
17644412826
-
In vitro anti-HIV potency of stampidine alone and in combination with standard anti-HIV drugs
-
Uckun FM, Qazi S, Venkatachalam TK (2005). In vitro anti-HIV potency of stampidine alone and in combination with standard anti-HIV drugs. Arzneimittelforschung 55: 223-231.
-
(2005)
Arzneimittelforschung
, vol.55
, pp. 223-231
-
-
Uckun, F.M.1
Qazi, S.2
Venkatachalam, T.K.3
-
25
-
-
0038627530
-
Toxicity and pharmacokinetics of stampidine in mice and rats
-
Uckun FM, Chen CL, Lisowski E, Mitcheltree GC, Venkatachalam TK, et al. (2003) Toxicity and pharmacokinetics of stampidine in mice and rats. Arzneimittelforschung 53: 357-367.
-
(2003)
Arzneimittelforschung
, vol.53
, pp. 357-367
-
-
Uckun, F.M.1
Chen, C.L.2
Lisowski, E.3
Mitcheltree, G.C.4
Venkatachalam, T.K.5
-
26
-
-
0034962198
-
In vivo pharmacokinetics and metabolism of anti-HIV agent D4T-5'-[p-bromophenyl methoxyalaninyl phosphate] in mice
-
Chen CL, Venkatachalam TK, Zhu ZH, Uckun FM (2001) In vivo pharmacokinetics and metabolism of anti-HIV agent D4T-5'-[p-bromophenyl methoxyalaninyl phosphate] in mice. Drug Metab Dispos 29: 1035-1041.
-
(2001)
Drug Metab Dispos
, vol.29
, pp. 1035-1041
-
-
Chen, C.L.1
Venkatachalam, T.K.2
Zhu, Z.H.3
Uckun, F.M.4
-
27
-
-
1842833698
-
Metabolism of stavudine-5'-[p-bromophenyl methoxy alaninyl phosphate], stampidine, in mice, dogs, and cats
-
Chen CL, Yu G, Venkatachalam T, Uckun FM (2002) Metabolism of stavudine-5'-[p-bromophenyl methoxy alaninyl phosphate], stampidine, in mice, dogs, and cats. Drug Metab Dispos 30: 1523-1531.
-
(2002)
Drug Metab Dispos
, vol.30
, pp. 1523-1531
-
-
Chen, C.L.1
Yu, G.2
Venkatachalam, T.3
Uckun, F.M.4
-
28
-
-
17844409371
-
Panel of prototypical infectious molecular HIV-1 clones containing multiple nucleoside reverse transcriptase inhibitor resistance mutations
-
Johnston E, Dupnik KM, Gonzales MJ, Winters MA, Rhee SY, et al. (2005) Panel of prototypical infectious molecular HIV-1 clones containing multiple nucleoside reverse transcriptase inhibitor resistance mutations. AIDS 19: 731-733.
-
(2005)
AIDS
, vol.19
, pp. 731-733
-
-
Johnston, E.1
Dupnik, K.M.2
Gonzales, M.J.3
Winters, M.A.4
Rhee, S.Y.5
-
29
-
-
0036841755
-
In vivo toxicity, pharmacokinetics, and anti-HIV activity of stavudine-5'-(p-bromo phenyl methoxyalaninyl phosphate) (stampidine) in mice
-
Uckun FM, Qazi S, Pendergrass S, Lisowski E, Waurzyniak B, et al. (2002) In vivo toxicity, pharmacokinetics, and anti-HIV activity of stavudine-5'-(p-bromo phenyl methoxyalaninyl phosphate) (stampidine) in mice. Antimicrob Agents Chemother 46: 3428-3436.
-
(2002)
Antimicrob Agents Chemother
, vol.46
, pp. 3428-3436
-
-
Uckun, F.M.1
Qazi, S.2
Pendergrass, S.3
Lisowski, E.4
Waurzyniak, B.5
-
30
-
-
0037378795
-
In vivo antiretroviral activity of stampidine in chronically FIV-infected cats
-
Uckun FM, Chen CL, Samuel P, Pendergrass S, Uckun FM (2003) In vivo antiretroviral activity of stampidine in chronically FIV-infected cats. Antimicrob Agents Chemother 47: 1233-1240.
-
(2003)
Antimicrob Agents Chemother
, vol.47
, pp. 1233-1240
-
-
Uckun, F.M.1
Chen, C.L.2
Samuel, P.3
Pendergrass, S.4
Uckun, F.M.5
-
31
-
-
33645101334
-
Large-scale synthesis and formulation of GMP-grade stampidine, a new anti-HIV agent
-
DuMez D, Venkatachalam TK, Uckun FM (2006) Large-scale synthesis and formulation of GMP-grade stampidine, a new anti-HIV agent. Arzneimittelforschung 56: 136-151.
-
(2006)
Arzneimittelforschung
, vol.56
, pp. 136-151
-
-
DuMez, D.1
Venkatachalam, T.K.2
Uckun, F.M.3
-
32
-
-
0036840520
-
Stampidine is a potent inhibitor of zidovudine and nucleoside analog reverse transcriptase inhibitor-resistant primary clinical HIV-1 isolates with thymidine analog mutations
-
Uckun FM, Pendergrass S, Venkatachalam TK, Qazi S, Richman D (2002) Stampidine is a potent inhibitor of zidovudine and nucleoside analog reverse transcriptase inhibitor-resistant primary clinical HIV-1 isolates with thymidine analog mutations. Antimicrob Agents Chemother 46: 3613-3616.
-
(2002)
Antimicrob Agents Chemother
, vol.46
, pp. 3613-3616
-
-
Uckun, F.M.1
Pendergrass, S.2
Venkatachalam, T.K.3
Qazi, S.4
Richman, D.5
-
33
-
-
33847719131
-
Anti-retroviral activity of GMP-grade stampidine against genotypically and phenotypically nucleoside reverse transcriptase inhibitor resistant recombinant human immunodeficiency virus. An in vitro study
-
Uckun FM, DuMez D, Qazi S, Tibbles H, Venkatachalam TK (2007) Anti-retroviral activity of GMP-grade stampidine against genotypically and phenotypically nucleoside reverse transcriptase inhibitor resistant recombinant human immunodeficiency virus. An in vitro study. Arzneimittelforschung 57: 112-121.
-
(2007)
Arzneimittelforschung
, vol.57
, pp. 112-121
-
-
Uckun, F.M.1
DuMez, D.2
Qazi, S.3
Tibbles, H.4
Venkatachalam, T.K.5
-
34
-
-
33645096955
-
In vivo pharmacokinetics and toxicity profile of the anti-HIV agent stampidine in dogs and feline immunodeficiency virus-infected cats
-
Uckun FM, Waurzyniak B, Tibbles H, Venkatachalam TK, Erbeck D (2006) In vivo pharmacokinetics and toxicity profile of the anti-HIV agent stampidine in dogs and feline immunodeficiency virus-infected cats. Arzneimittelforschung 56: 176-192.
-
(2006)
Arzneimittelforschung
, vol.56
, pp. 176-192
-
-
Uckun, F.M.1
Waurzyniak, B.2
Tibbles, H.3
Venkatachalam, T.K.4
Erbeck, D.5
|