-
1
-
-
0035822016
-
AIDS - The first 20 years
-
Sepkowitz, K. A., AIDS - the first 20 years. N. Engl. J. Med. 344, 1764 (2001)
-
(2001)
N. Engl. J. Med.
, vol.344
, pp. 1764
-
-
Sepkowitz, K.A.1
-
2
-
-
0035822008
-
AIDS - Past and future
-
Gottlieb, M. S., AIDS - past and future. N. Engl. J. Med. 344, 1788 (2001)
-
(2001)
N. Engl. J. Med.
, vol.344
, pp. 1788
-
-
Gottlieb, M.S.1
-
3
-
-
0035869435
-
The cost effectiveness of combination antiretroviral therapy for HIV disease
-
Freedberg, K. A., Losina, E., Weinstein, M. C., et al., The cost effectiveness of combination antiretroviral therapy for HIV disease. N. Engl. J. Med. 344, 824 (2001)
-
(2001)
N. Engl. J. Med.
, vol.344
, pp. 824
-
-
Freedberg, K.A.1
Losina, E.2
Weinstein, M.C.3
-
4
-
-
0035912249
-
HIV chemotherapy
-
Richman, D. D., HIV chemotherapy. Nature 410, 995 (2001)
-
(2001)
Nature
, vol.410
, pp. 995
-
-
Richman, D.D.1
-
5
-
-
0033102304
-
Highly active antiretroviral therapy (HAART) for the treatment of infection with human immunodeficiency virus type 1
-
Shafer, R. W., Vuitton, D. A., Highly active antiretroviral therapy (HAART) for the treatment of infection with human immunodeficiency virus type 1. Biomed Pharmacother. 53, 73 (1999)
-
(1999)
Biomed Pharmacother.
, vol.53
, pp. 73
-
-
Shafer, R.W.1
Vuitton, D.A.2
-
6
-
-
0033576814
-
Combination therapy with efavirenz, nelfinavir, and nucleoside reverse-transcriptase inhibitors in children infected with human immunodeficiency virus type 1
-
Pediatric AIDS Clinical Trials Group 382 Team
-
Starr, S. E., Fletcher, C. V, Spector, S. A., et al., Combination therapy with efavirenz, nelfinavir, and nucleoside reverse-transcriptase inhibitors in children infected with human immunodeficiency virus type 1. Pediatric AIDS Clinical Trials Group 382 Team. N. Engl. J. Med. 341, 1874 (1999)
-
(1999)
N. Engl. J. Med.
, vol.341
, pp. 1874
-
-
Starr, S.E.1
Fletcher, C.V.2
Spector, S.A.3
-
7
-
-
0035880929
-
Efavirenz as a substitute for protease inhibitors in HIV-1-infected patients with undetectable plasma viral load on HAART: A median follow-up of 64 weeks
-
Rey, D., Schmitt, M. P., Partisani, M., et al., Efavirenz as a substitute for protease inhibitors in HIV-1-infected patients with undetectable plasma viral load on HAART: a median follow-up of 64 weeks. J. Acquir. Immune Defic. Syndr. 27, 459 (2001)
-
(2001)
J. Acquir. Immune Defic. Syndr.
, vol.27
, pp. 459
-
-
Rey, D.1
Schmitt, M.P.2
Partisani, M.3
-
8
-
-
0033995190
-
HIV-1 reverse transcriptase (RT) genotype and susceptibility to RT inhibitors during abacavir monotherapy and combination therapy
-
Miller, V., Ait-Khaled, M., Stone, C. et al., HIV-1 reverse transcriptase (RT) genotype and susceptibility to RT inhibitors during abacavir monotherapy and combination therapy. AIDS 14, 163 (2000)
-
(2000)
AIDS
, vol.14
, pp. 163
-
-
Miller, V.1
Ait-Khaled, M.2
Stone, C.3
-
9
-
-
0034828314
-
Thymidine analog and multinucleoside resistance mutations are associated with decreased phenotypic susceptibility to stavudine in hiv type 1 isolated from zidovudine-naive patients experiencing viremia on stavudine-containing regimens
-
Ross, L., Scarsella, A., Raffanti, S. et al., Thymidine analog and multinucleoside resistance mutations are associated with decreased phenotypic susceptibility to stavudine in hiv type 1 isolated from zidovudine-naive patients experiencing viremia on stavudine-containing regimens. AIDS Res. Hum. Retroviruses 17, 1107 (2001)
-
(2001)
AIDS Res. Hum. Retroviruses
, vol.17
, pp. 1107
-
-
Ross, L.1
Scarsella, A.2
Raffanti, S.3
-
10
-
-
0001822944
-
Phenotypic and genotypic resistance patterns of HIV-1 isolates derived from individuals treated with didanosine and stavudine
-
Coakley, E. P., Gillis, J. M., Hammer, S. M., Phenotypic and genotypic resistance patterns of HIV-1 isolates derived from individuals treated with didanosine and stavudine. AIDS 14, F9 (2000)
-
(2000)
AIDS
, vol.14
-
-
Coakley, E.P.1
Gillis, J.M.2
Hammer, S.M.3
-
11
-
-
0028952415
-
Nucleoside reverse transcriptase inhibitors and resistance of human immunodeficiency virus type 1
-
Johnson, V. A., Nucleoside reverse transcriptase inhibitors and resistance of human immunodeficiency virus type 1. J. Infect. Dis. 171, S140 (1995)
-
(1995)
J. Infect. Dis.
, vol.171
-
-
Johnson, V.A.1
-
12
-
-
0032898472
-
Stavudine resistance: An update on susceptibility following prolonged therapy
-
Lin, P. F., Gonzalez, C. J., Griffith, B. et al., Stavudine resistance: an update on susceptibility following prolonged therapy. Antivir. Ther. 4, 21 (1999)
-
(1999)
Antivir. Ther.
, vol.4
, pp. 21
-
-
Lin, P.F.1
Gonzalez, C.J.2
Griffith, B.3
-
13
-
-
0034807862
-
Novel deletion of HIV type 1 reverse transcriptase residue 69 conferring selective high-level resistance to nevirapine
-
Suzuki, K., Kaufmann, G. R., Mukaide, M. et al., Novel deletion of HIV type 1 reverse transcriptase residue 69 conferring selective high-level resistance to nevirapine. AIDS Res. Hum. Retroviruses 17, 1293 (2001)
-
(2001)
AIDS Res. Hum. Retroviruses
, vol.17
, pp. 1293
-
-
Suzuki, K.1
Kaufmann, G.R.2
Mukaide, M.3
-
14
-
-
0035884247
-
Comparison of genotypic and phenotypic resistance patterns of human immunodeficiency virus type 1 isolates from patients treated with stavudine and didanosine or zidovudine and lamivudine
-
Picard, V., Angelini, E., Maillard, A. et al., Comparison of genotypic and phenotypic resistance patterns of human immunodeficiency virus type 1 isolates from patients treated with stavudine and didanosine or zidovudine and lamivudine. J. Infect. Dis. 184, 781 (2001)
-
(2001)
J. Infect. Dis.
, vol.184
, pp. 781
-
-
Picard, V.1
Angelini, E.2
Maillard, A.3
-
15
-
-
0035881021
-
Adefovir and tenofovir susceptibilities of HIV-1 after 24 to 48 weeks of adefovir dipivoxil therapy: Genotypic and phenotypic analyses of study GS-96-408
-
Miller, M. D., Margot, N. A., Lamy, P. D. et al., Adefovir and tenofovir susceptibilities of HIV-1 after 24 to 48 weeks of adefovir dipivoxil therapy: genotypic and phenotypic analyses of study GS-96-408. J. Acquir. Immune Defic. Syndr. 27, 450 (2001)
-
(2001)
J. Acquir. Immune Defic. Syndr.
, vol.27
, pp. 450
-
-
Miller, M.D.1
Margot, N.A.2
Lamy, P.D.3
-
16
-
-
0035424029
-
Genotypic correlates of a virologic response to stavudine after zidovudine monotherapy
-
The AIDS Clinical Trials Group 302 Study Team
-
Shulman, N. S., Machekano, R. A., Shafer, R. W. et al., The AIDS Clinical Trials Group 302 Study Team. Genotypic correlates of a virologic response to stavudine after zidovudine monotherapy. J. Acquir. Immune Defic. Syndr. 27, 377 (2001)
-
(2001)
J. Acquir. Immune Defic. Syndr.
, vol.27
, pp. 377
-
-
Shulman, N.S.1
Machekano, R.A.2
Shafer, R.W.3
-
17
-
-
0032693960
-
Mutations conferring resistance to zidovudine diminish the antiviral effect of stavudine plus didanosine
-
Izopet, J., Bicart-See, A., Pasquier, C. et al., Mutations conferring resistance to zidovudine diminish the antiviral effect of stavudine plus didanosine. J. Med. Virol. 59, 507 (1999)
-
(1999)
J. Med. Virol.
, vol.59
, pp. 507
-
-
Izopet, J.1
Bicart-See, A.2
Pasquier, C.3
-
18
-
-
0032722339
-
Genotypic resistance to zidovudine as a predictor of failure of subsequent therapy with human immunodeficiency virus type-1 nucleoside reverse-transcriptase inhibitors
-
Venturi, G., Romano, L., Catucci, M, et al., Genotypic resistance to zidovudine as a predictor of failure of subsequent therapy with human immunodeficiency virus type-1 nucleoside reverse-transcriptase inhibitors. Eur. J. Clin. Microbiol. Infect. Dis. 18, 274 (1999)
-
(1999)
Eur. J. Clin. Microbiol. Infect. Dis.
, vol.18
, pp. 274
-
-
Venturi, G.1
Romano, L.2
Catucci, M.3
-
19
-
-
0034006789
-
Effect of zidovudine resistance mutations on virologic response to treatment with zidovudine-lamivudine-ritonavir: Genotypic analysis of human immunodeficiency virus type 1 isolates from AIDS clinical trials group protocol 315
-
ACTG Protocol 315 Team
-
Kuritzkes, D. R., Sevin, A., Young, B. et al., Effect of zidovudine resistance mutations on virologic response to treatment with zidovudine-lamivudine-ritonavir: genotypic analysis of human immunodeficiency virus type 1 isolates from AIDS clinical trials group protocol 315.ACTG Protocol 315 Team, J. Infect. Dis. 181, 491 (2000)
-
(2000)
J. Infect. Dis.
, vol.181
, pp. 491
-
-
Kuritzkes, D.R.1
Sevin, A.2
Young, B.3
-
20
-
-
0034456474
-
Resistance against reverse transcriptase inhibitors
-
O'Brien, W. A., Resistance against reverse transcriptase inhibitors. Clin. Infect. Dis. 30, S185 (2000)
-
(2000)
Clin. Infect. Dis.
, vol.30
-
-
O'Brien, W.A.1
-
21
-
-
0033940444
-
Incidence and impact of resistance against approved antiretroviral drugs
-
Pillay, D., Taylor, S., Richman, D. D., Incidence and impact of resistance against approved antiretroviral drugs. Rev. Med. Virol. 10, 231 (2000)
-
(2000)
Rev. Med. Virol.
, vol.10
, pp. 231
-
-
Pillay, D.1
Taylor, S.2
Richman, D.D.3
-
22
-
-
0035141058
-
Patterns of resistance mutations to antiretroviral drugs in extensively treated HIV-1-infected patients with failure of highly active antiretroviral therapy
-
Rousseau, M. N., Vergne, L., Montes, B. et al., Patterns of resistance mutations to antiretroviral drugs in extensively treated HIV-1-infected patients with failure of highly active antiretroviral therapy. J. Acquir. Immune Defic. Syndr. 26, 36 (2001)
-
(2001)
J. Acquir. Immune Defic. Syndr.
, vol.26
, pp. 36
-
-
Rousseau, M.N.1
Vergne, L.2
Montes, B.3
-
23
-
-
0033821131
-
Prevalence of drug-resistant HIV-1 genotypes in heavily pre-treated patients on current virological failure
-
Briones, C., Soriano, V., Gonzalez-Lahoz, J., Prevalence of drug-resistant HIV-1 genotypes in heavily pre-treated patients on current virological failure. Aids 14, 1659 (2000)
-
(2000)
Aids
, vol.14
, pp. 1659
-
-
Briones, C.1
Soriano, V.2
Gonzalez-Lahoz, J.3
-
24
-
-
0343807004
-
Genotypic resistance to antiretroviral drugs in patients with therapeutic failure to highly active antiretroviral therapy
-
Gutierrez, F., Molto, J., Escolano, C. et al., Genotypic resistance to antiretroviral drugs in patients with therapeutic failure to highly active antiretroviral therapy. Med. Clin. (Barc). 115, 401 (2000)
-
(2000)
Med. Clin. (Barc).
, vol.115
, pp. 401
-
-
Gutierrez, F.1
Molto, J.2
Escolano, C.3
-
25
-
-
0033022106
-
Highly drug-resistant HIV-1 clinical isolates are cross-resistant to many antiretroviral compounds in current clinical development
-
Palmer, S., Shafer, R. W., Merigan, T. C., Highly drug-resistant HIV-1 clinical isolates are cross-resistant to many antiretroviral compounds in current clinical development. AIDS 13, 661 (1999)
-
(1999)
AIDS
, vol.13
, pp. 661
-
-
Palmer, S.1
Shafer, R.W.2
Merigan, T.C.3
-
26
-
-
0035280397
-
Frequency of genotypic and phenotypic drug-resistant HIV-1 among therapy-naive patients of the German Seroconverter Study
-
Duwe, S., Brunn, M., Altmann, D. et al., Frequency of genotypic and phenotypic drug-resistant HIV-1 among therapy-naive patients of the German Seroconverter Study. J. Acquir. Immune Defic. Syndr. 26, 266 (2001)
-
(2001)
J. Acquir. Immune Defic. Syndr.
, vol.26
, pp. 266
-
-
Duwe, S.1
Brunn, M.2
Altmann, D.3
-
27
-
-
0002035867
-
Prevalence of HIV-1 resistant to antiretroviral drugs in 81 individuals newly infected by sexual contact or injecting drug use
-
Investigators of the Quebec Primary Infection Study
-
Salomon, H., Wainberg, M. A., Brenner, B. et al., Prevalence of HIV-1 resistant to antiretroviral drugs in 81 individuals newly infected by sexual contact or injecting drug use. Investigators of the Quebec Primary Infection Study. AIDS 14, F17 (2000)
-
(2000)
AIDS
, vol.14
-
-
Salomon, H.1
Wainberg, M.A.2
Brenner, B.3
-
28
-
-
17644426383
-
-
Aryl Phosphate Derivatives of d4T Having Anti-HIV Activity, US Patent Number 6,030,957, issue date 2/29/00, Uckun, F. M., Vig, R., Parker Hughes Institute, St. Paul, MN (USA)
-
Aryl Phosphate Derivatives of d4T Having Anti-HIV Activity, US Patent Number 6,030,957, issue date 2/29/00, Uckun, F. M., Vig, R., Parker Hughes Institute, St. Paul, MN (USA)
-
-
-
-
29
-
-
0027515958
-
Anti-human immunodeficiency virus type 1 activity of an anti-CD4 immunoconjugate containing pokeweed antiviral protein
-
Erice, A., Balfour, H. H., Jr., Myers, D. E. et al., Anti-human immunodeficiency virus type 1 activity of an anti-CD4 immunoconjugate containing pokeweed antiviral protein. Antimicrob. Agents Chemother. 37, 835 (1993)
-
(1993)
Antimicrob. Agents Chemother.
, vol.37
, pp. 835
-
-
Erice, A.1
Balfour Jr., H.H.2
Myers, D.E.3
-
30
-
-
0011129306
-
-
Unit 12.1-12.5. John Wiley & Sons, Brooklyn, NY
-
Richman, D. D., Johnson, V. A., Mayers, D. L. et al., Current Protocols in Immunology, Suppl 8, Unit 12.1-12.5. John Wiley & Sons, Brooklyn, NY (1993)
-
(1993)
Current Protocols in Immunology
, Issue.SUPPL. 8
-
-
Richman, D.D.1
Johnson, V.A.2
Mayers, D.L.3
-
31
-
-
0031943905
-
TXU (anti-CD7)-pokeweed antiviral protein as a potent inhibitor of human immunodeficiency virus
-
Uckun, F. M., Chelstrom, L. M., Tuel-Ahlgren, L. et al., TXU (anti-CD7)-pokeweed antiviral protein as a potent inhibitor of human immunodeficiency virus. Antimicrob. Agents Chemother. 42, 383 (1998)
-
(1998)
Antimicrob. Agents Chemother.
, vol.42
, pp. 383
-
-
Uckun, F.M.1
Chelstrom, L.M.2
Tuel-Ahlgren, L.3
-
32
-
-
0029036955
-
The search for synergy: A critical review from a response surface perspective
-
Greco, W. R., Bravo, G., Parsons, J. C., The search for synergy: a critical review from a response surface perspective. Pharmacol. Rev. 47, 331 (1995)
-
(1995)
Pharmacol. Rev.
, vol.47
, pp. 331
-
-
Greco, W.R.1
Bravo, G.2
Parsons, J.C.3
-
33
-
-
0033118758
-
CombiTool-a new computer program for analyzing combination experiments with biologically active agents
-
Dressler, V., Muller, G., Suhnel, J., CombiTool-a new computer program for analyzing combination experiments with biologically active agents. Comput, Biomed. Res. 32, 145 (1999)
-
(1999)
Comput, Biomed. Res.
, vol.32
, pp. 145
-
-
Dressler, V.1
Muller, G.2
Suhnel, J.3
-
34
-
-
0034069420
-
The triple combination indinavir-zidovudine-lamivudine is highly synergistic
-
Snyder, S., D'Argenio, D. Z., Weislow, O. et al., The triple combination indinavir-zidovudine-lamivudine is highly synergistic. Antimicrob, Agents Chemother. 44, 1051 (2000)
-
(2000)
Antimicrob, Agents Chemother.
, vol.44
, pp. 1051
-
-
Snyder, S.1
D'Argenio, D.Z.2
Weislow, O.3
-
35
-
-
0030952601
-
Clinical pharmacokinetics of stavudine
-
Rana, K. Z., Dudley, M. N., Clinical pharmacokinetics of stavudine. Clin. Pharmacokinet. 33, 276 (1997)
-
(1997)
Clin. Pharmacokinet.
, vol.33
, pp. 276
-
-
Rana, K.Z.1
Dudley, M.N.2
-
36
-
-
0032542075
-
Enhancing ffects of a mono-bromo substitution at the para position of the phenyl moiety on the metabolism and anti-HIV activity of D4T-phenyl methoxyalaninyl phosphate derivatives
-
Venkatachalam, T. K., Tai, H.-L., Vig, R. et al., Enhancing Effects of a Mono-Bromo Substitution at the Para Position of the Phenyl Moiety on the Metabolism and Anti-HIV Activity of D4T-Phenyl Methoxyalaninyl Phosphate Derivatives. Bioorg. Med. Chem. Lett. 8, 3121 (1998)
-
(1998)
Bioorg. Med. Chem. Lett.
, vol.8
, pp. 3121
-
-
Venkatachalam, T.K.1
Tai, H.-L.2
Vig, R.3
-
37
-
-
0031715789
-
D4T-5'-[p-bromophenyl methoxyalaninyl phosphate] as a potent and non- toxic anti-human immunodeficiency virus agent
-
Vig, R., Venkatachalam, T. K., Uckun, F. M., D4T-5'-[p-bromophenyl methoxyalaninyl phosphate] as a potent and non- toxic anti-human immunodeficiency virus agent. Antivir. Chem. Chemother. 9, 445 (1998)
-
(1998)
Antivir. Chem. Chemother.
, vol.9
, pp. 445
-
-
Vig, R.1
Venkatachalam, T.K.2
Uckun, F.M.3
-
38
-
-
0036840520
-
Stampidine is a potent inhibitor of Zidovudine- and nucleoside analog reverse transcriptase inhibitor-resistant primary clinical human immunodeficiency virus type 1 isolates with thymidine analog mutations
-
Uckun, F, M., Pendergrass, S., Venkatachalam, T. K. et al., Stampidine is a potent inhibitor of Zidovudine- and nucleoside analog reverse transcriptase inhibitor-resistant primary clinical human immunodeficiency virus type 1 isolates with thymidine analog mutations. Antimicrob. Agents Chemother, 46, 3613 (2002)
-
(2002)
Antimicrob. Agents Chemother
, vol.46
, pp. 3613
-
-
Uckun, F.M.1
Pendergrass, S.2
Venkatachalam, T.K.3
-
39
-
-
0742322029
-
In vitro activity of Stampidine against primary clinical human immunodeficiency virus isolates
-
Uckun, F. M., Pendergrass, S., Qazi, S. et al., In vitro activity of Stampidine against primary clinical human immunodeficiency virus isolates, Arzneim.-Forsch./Drug Res, 54, 69 (2004)
-
(2004)
Arzneim.-Forsch./Drug Res
, vol.54
, pp. 69
-
-
Uckun, F.M.1
Pendergrass, S.2
Qazi, S.3
-
40
-
-
0034962198
-
In vivo pharmacokinetics and metabolism of Stampidine, a novel aryl phosphate derivative of d4T with potent anti-HIV activity
-
Chen, C., Venkatachalam, T. K., Zhu, Z. et al., In vivo pharmacokinetics and metabolism of Stampidine, a novel aryl phosphate derivative of d4T with potent anti-HIV activity. Drug Metab. Dispos. 29, 1035 (2001)
-
(2001)
Drug Metab. Dispos.
, vol.29
, pp. 1035
-
-
Chen, C.1
Venkatachalam, T.K.2
Zhu, Z.3
-
41
-
-
0036841755
-
In vivo toxicity, pharmacokinetics, and anti-human immunodeficiency virus activity of stavudine-5′-(p-bromophenyl methoxyalaninyl phosphate) (Stampidine) in mice
-
Uckun, F. M., Qazi, S., Pendergrass, S. et al., In vivo toxicity, pharmacokinetics, and anti-human immunodeficiency virus activity of stavudine-5′-(p-bromophenyl methoxyalaninyl phosphate) (Stampidine) in mice. Antimicrob, Agents Chemother, 46, 3428 (2002)
-
(2002)
Antimicrob, Agents Chemother
, vol.46
, pp. 3428
-
-
Uckun, F.M.1
Qazi, S.2
Pendergrass, S.3
-
42
-
-
0037378795
-
In vivo antiretroviral activity of Stampidine in chronically feline immunodeficiency virus-infected cats
-
Uckun, F. M., Chen, C. L., Samuel, P. et al., In vivo antiretroviral activity of Stampidine in chronically feline immunodeficiency virus-infected cats. Antimicrob. Agents Chemother. 47, 1233 (2003)
-
(2003)
Antimicrob. Agents Chemother.
, vol.47
, pp. 1233
-
-
Uckun, F.M.1
Chen, C.L.2
Samuel, P.3
-
43
-
-
1542513385
-
Stampidine is a potential nonspermicidal broad-spectrum anti-human immunodeficiency virus microbicide
-
D'Cruz, O. J., Uckun, F. M., Stampidine is a potential nonspermicidal broad-spectrum anti-human immunodeficiency virus microbicide. Fertil. Steril. 81 (Suppl. 1), 831 (2004)
-
(2004)
Fertil. Steril.
, vol.81
, Issue.SUPPL. 1
, pp. 831
-
-
D'Cruz, O.J.1
Uckun, F.M.2
-
44
-
-
0345169183
-
Development and evaluation of a thermoreversible ovule formulation of stampidine, a novel nonspermicidal broad-spectrum antihuman immunodeficiency virus microbicide
-
D'Cruz, O. J., Samuel, P., Waurzyniak, B. et al., Development and evaluation of a thermoreversible ovule formulation of stampidine, a novel nonspermicidal broad-spectrum antihuman immunodeficiency virus microbicide. Biol. Reprod. 69, 1843 (2003)
-
(2003)
Biol. Reprod.
, vol.69
, pp. 1843
-
-
D'Cruz, O.J.1
Samuel, P.2
Waurzyniak, B.3
-
45
-
-
0038627530
-
Toxicity and pharmacokinetics of Stampidine in mice and rats
-
Uckun, F. M., Chen, C. L., Lisowski, E. et al., Toxicity and pharmacokinetics of Stampidine in mice and rats. Arzneim,-Forsch./Drug Res. 53, 357 (2003)
-
(2003)
Arzneim,-Forsch./Drug Res.
, vol.53
, pp. 357
-
-
Uckun, F.M.1
Chen, C.L.2
Lisowski, E.3
|