-
2
-
-
66549127501
-
ACCF/AHA 2009 expert consensus document on pulmonary hypertension: A report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association: developed in collaboration with the American College of Chest Physicians, American Thoracic Society, Inc., and the Pulmonary Hypertension Association
-
McLaughlin, V.V., Archer, S.L., Badesch, D.B. et al. ACCF/AHA 2009 expert consensus document on pulmonary hypertension: a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association: developed in collaboration with the American College of Chest Physicians, American Thoracic Society, Inc., and the Pulmonary Hypertension Association. Circulation 2009, 119(16): 2250-94.
-
(2009)
Circulation
, vol.119
, Issue.16
, pp. 2250-2294
-
-
McLaughlin, V.V.1
Archer, S.L.2
Badesch, D.B.3
-
4
-
-
76749107077
-
Study of the BMPR2 gene in patients with pulmonary arterial hypertension
-
Portillo, K., Santos, S., Madrigal, I. et al. [Study of the BMPR2 gene in patients with pulmonary arterial hypertension]. Arch Bronconeumol 2010, 46(3): 129-34.
-
(2010)
Arch Bronconeumol
, vol.46
, Issue.3
, pp. 129-134
-
-
Portillo, K.1
Santos, S.2
Madrigal, I.3
-
5
-
-
2942522878
-
Clinical classification of pulmonary hypertension
-
DOI 10.1016/j.jacc.2004.02.037, PII S0735109704004759
-
Simonneau, G., Galie, N., Rubin, L. et al. Clinical classification of pulmonary hypertension. J Am Coll Cardiol 2004, 43(12, Suppl. S): 5S-12S. (Pubitemid 38759712)
-
(2004)
Journal of the American College of Cardiology
, vol.43
, Issue.12 SUPPL.
-
-
Simonneau, G.1
Galie, N.2
Rubin, L.J.3
Langleben, D.4
Seeger, W.5
Domenighetti, G.6
Gibbs, S.7
Lebrec, D.8
Speich, R.9
Beghetti, M.10
Rich, S.11
Fishman, A.12
-
6
-
-
67649579669
-
Updated clinical classification of pulmonary hypertension
-
Simonneau, G., Robbins, I.M., Beghetti, M. et al. Updated clinical classification of pulmonary hypertension. J Am Coll Cardiol 2009, 54(1, Suppl.): S43-54.
-
(2009)
J Am Coll Cardiol
, vol.54
, Issue.1 SUPPL.
-
-
Simonneau, G.1
Robbins, I.M.2
Beghetti, M.3
-
8
-
-
77949347401
-
Endothelial cell processing and alternatively spliced transcripts of factor VIII: Potential implications for coagulation cascades and pulmonary hypertension
-
Shovlin, C.L., Angus, G., Manning, R.A. et al. Endothelial cell processing and alternatively spliced transcripts of factor VIII: potential implications for coagulation cascades and pulmonary hypertension. PLoS One 2010, 5(2): e9154.
-
(2010)
PLoS One
, vol.5
, Issue.2
-
-
Shovlin, C.L.1
Angus, G.2
Manning, R.A.3
-
9
-
-
2942659888
-
Tissue factor binding of activated factor VII triggers smooth muscle cell proliferation via extracellular signal-regulated kinase activation
-
DOI 10.1161/01.CIR.0000129312.43547.08
-
Cirillo, P., Cali, G., Golino, P. et al. Tissue factor binding of activated factor VII triggers smooth muscle cell proliferation via extracellular signal-regulated kinase activation. Circulation 2004, 109(23): 2911-6. (Pubitemid 38780307)
-
(2004)
Circulation
, vol.109
, Issue.23
, pp. 2911-2916
-
-
Cirillo, P.1
Cali, G.2
Golino, P.3
Calabro, P.4
Forte, L.5
De Rosa, S.6
Pacileo, M.7
Ragni, M.8
Scopacasa, F.9
Nitsch, L.10
Chiariello, M.11
-
10
-
-
30944461398
-
Thromboembolic adverse events after use of recombinant human coagulation factor VIIa
-
DOI 10.1001/jama.295.3.293
-
O'Connell, K.A., Wood, J.J., Wise, R.P., Lozier, J.N. Braun, M.M. Thromboembolic adverse events after use of recombinant human coagulation factor VIIa. JAMA 2006, 295(3): 293-8. (Pubitemid 43112957)
-
(2006)
Journal of the American Medical Association
, vol.295
, Issue.3
, pp. 293-298
-
-
O'Connell, K.A.1
Wood, J.J.2
Wise, R.P.3
Lozier, J.N.4
Miles, B.M.5
-
11
-
-
66249133083
-
Evidence for angiotensin-converting enzyme 2 as a therapeutic target for the prevention of pulmonary hypertension
-
Ferreira, A.J., Shenoy, V., Yamazato, Y. et al. Evidence for angiotensin-converting enzyme 2 as a therapeutic target for the prevention of pulmonary hypertension. Am J Respir Crit Care Med 2009, 179(11): 1048-54.
-
(2009)
Am J Respir Crit Care Med
, vol.179
, Issue.11
, pp. 1048-1054
-
-
Ferreira, A.J.1
Shenoy, V.2
Yamazato, Y.3
-
12
-
-
68549122789
-
Prevention of pulmonary hypertension by angiotensin-converting enzyme 2 gene transfer
-
Yamazato, Y., Ferreira, A.J., Hong, K.H. et al. Prevention of pulmonary hypertension by angiotensin-converting enzyme 2 gene transfer. Hypertension 2009, 54(2): 365-71.
-
(2009)
Hypertension
, vol.54
, Issue.2
, pp. 365-371
-
-
Yamazato, Y.1
Ferreira, A.J.2
Hong, K.H.3
-
13
-
-
77952543051
-
Losartan attenuates chronic cigarette smoke exposure-induced pulmonary arterial hypertension in rats: Possible involvement of angiotensin-converting enzyme-2
-
Han, S.X., He, G.M., Wang, T. et al. Losartan attenuates chronic cigarette smoke exposure-induced pulmonary arterial hypertension in rats: possible involvement of angiotensin-converting enzyme-2. Toxicol Appl Pharmacol 2010, 245(1): 100-7.
-
(2010)
Toxicol Appl Pharmacol
, vol.245
, Issue.1
, pp. 100-107
-
-
Han, S.X.1
He, G.M.2
Wang, T.3
-
14
-
-
77954083190
-
Epigenetic attenuation of mitochondrial superoxide dismutase 2 in pulmonary arterial hypertension: A basis for excessive cell proliferation and a new therapeutic target
-
Archer, S.L., Marsboom, G., Kim, G.H. et al. Epigenetic attenuation of mitochondrial superoxide dismutase 2 in pulmonary arterial hypertension: a basis for excessive cell proliferation and a new therapeutic target. Circulation 2010, 121(24): 2661-71.
-
(2010)
Circulation
, vol.121
, Issue.24
, pp. 2661-2671
-
-
Archer, S.L.1
Marsboom, G.2
Kim, G.H.3
-
15
-
-
0038369941
-
Vasoactive intestinal peptide as a new drug for treatment of primary pulmonary hypertension
-
DOI 10.1172/JCI200317500
-
Petkov, V., Mosgoeller, W., Ziesche, R. et al. Vasoactive intestinal peptide as a new drug for treatment of primary pulmonary hypertension. J Clin Invest 2003, 111(9): 1339-46. (Pubitemid 36554704)
-
(2003)
Journal of Clinical Investigation
, vol.111
, Issue.9
, pp. 1339-1346
-
-
Petkov, V.1
Mosgoeller, W.2
Ziesche, R.3
Raderer, M.4
Stiebellehner, L.5
Vonbank, K.6
Funk, G.-C.7
Hamilton, G.8
Novotny, C.9
Burian, B.10
Block, L.-H.11
-
16
-
-
77957224956
-
Long-term outcomes in pulmonary arterial hypertension in the first-line epoprostenol or first-line bosentan era
-
Jacobs, W., Boonstra, A., Brand, M., Rosenberg, D.M., Schaaf, B., Postmus, P.E., Vonk Noordegraaf, A. Long-term outcomes in pulmonary arterial hypertension in the first-line epoprostenol or first-line bosentan era. J Heart Lung Transplant 2010, 29(10): 1150-8.
-
(2010)
J Heart Lung Transplant
, vol.29
, Issue.10
, pp. 1150-1158
-
-
Jacobs, W.1
Boonstra, A.2
Brand, M.3
Rosenberg, D.M.4
Schaaf, B.5
Postmus, P.E.6
Vonk Noordegraaf, A.7
-
17
-
-
47549106387
-
Treprostinil-based therapy in the treatment of moderate-to-severe pulmonary arterial hypertension
-
DOI 10.1378/chest.07-2111
-
Benza, R.L., Rayburn, B.K., Tallaj, J.A., Pamboukian, S.V., Bourge, R.C. Treprostinil-based therapy in the treatment of moderate-to-severe pulmonary arterial hypertension: longterm efficacy and combination with bosentan. Chest 2008, 134(1): 139-45. (Pubitemid 352008775)
-
(2008)
Chest
, vol.134
, Issue.1
, pp. 139-145
-
-
Benza, R.L.1
Rayburn, B.K.2
Tallaj, J.A.3
Pamboukian, S.V.4
Bourge, R.C.5
-
18
-
-
58349110755
-
Metered dose inhaler delivery of treprostinil for the treatment of pulmonary hypertension
-
Voswinckel, R., Reichenberger, F., Gall, H. et al. Metered dose inhaler delivery of treprostinil for the treatment of pulmonary hypertension. Pulm Pharmacol Ther 2009, 22(1): 50-6.
-
(2009)
Pulm Pharmacol Ther
, vol.22
, Issue.1
, pp. 50-56
-
-
Voswinckel, R.1
Reichenberger, F.2
Gall, H.3
-
19
-
-
77952301237
-
Addition of inhaled treprostinil to oral therapy for pulmonary arterial hypertension: A randomized controlled clinical trial
-
McLaughlin, V.V., Benza, R.L., Rubin, L.J. et al. Addition of inhaled treprostinil to oral therapy for pulmonary arterial hypertension: a randomized controlled clinical trial. J Am Coll Cardiol 2010, 55(18): 1915-22.
-
(2010)
J Am Coll Cardiol
, vol.55
, Issue.18
, pp. 1915-1922
-
-
McLaughlin, V.V.1
Benza, R.L.2
Rubin, L.J.3
-
20
-
-
50849116416
-
Acute effects of the combination of sildenafil and inhaled treprostinil on haemodynamics and gas exchange in pulmonary hypertension
-
Voswinckel, R., Reichenberger, F., Enke, B. et al. Acute effects of the combination of sildenafil and inhaled treprostinil on haemodynamics and gas exchange in pulmonary hypertension. Pulm Pharmacol Ther 2008, 21(5): 824-32.
-
(2008)
Pulm Pharmacol Ther
, vol.21
, Issue.5
, pp. 824-832
-
-
Voswinckel, R.1
Reichenberger, F.2
Enke, B.3
-
21
-
-
77951621266
-
Long-term therapy with inhaled iloprost in patients with pulmonary hypertension
-
Olschewski, H., Hoeper, M.M., Behr, J. et al. Long-term therapy with inhaled iloprost in patients with pulmonary hypertension. Respir Med 2010, 104(5): 731-40.
-
(2010)
Respir Med
, vol.104
, Issue.5
, pp. 731-740
-
-
Olschewski, H.1
Hoeper, M.M.2
Behr, J.3
-
22
-
-
79251596905
-
Intravenous epoprostenol versus high dose inhaled iloprost for long-term treatment of pulmonary hypertension
-
Reichenberger, F., Mainwood, A., Morrell, N.W., Parameshwar, J., Zaba, J.P. Intravenous epoprostenol versus high dose inhaled iloprost for long-term treatment of pulmonary hypertension. Pulm Pharmacol Ther 2011, 24(1): 169-73.
-
(2011)
Pulm Pharmacol Ther
, vol.24
, Issue.1
, pp. 169-173
-
-
Reichenberger, F.1
Mainwood, A.2
Morrell, N.W.3
Parameshwar, J.4
Zaba, J.P.5
-
23
-
-
0037149718
-
Bosentan therapy for pulmonary arterial hypertension
-
DOI 10.1056/NEJMoa012212
-
Rubin, L.J., Badesch, D.B., Barst, R.J. et al. Bosentan therapy for pulmonary arterial hypertension. N Engl J Med 2002, 346(12): 896-903. (Pubitemid 34984638)
-
(2002)
New England Journal of Medicine
, vol.346
, Issue.12
, pp. 896-903
-
-
Rubin, L.J.1
Badesch, D.B.2
Barst, R.J.3
Galie, N.4
Black, C.M.5
Keogh, A.6
Pulido, T.7
Frost, A.8
Roux, S.9
Leconte, I.10
Landzberg, M.11
Simonneau, G.12
-
24
-
-
33846349509
-
Long-term outcomes of treatment with bosentan in pulmonary hypertension
-
Roman, A., Gispert, P., Monforte, V., Bravo, C., Domingo, E., Morell, F. [Long-term outcomes of treatment with bosentan in pulmonary hypertension]. Arch Bronconeumol 2006, 42(12): 616-20.
-
(2006)
Arch Bronconeumol
, vol.42
, Issue.12
, pp. 616-620
-
-
Roman, A.1
Gispert, P.2
Monforte, V.3
Bravo, C.4
Domingo, E.5
Morell, F.6
-
25
-
-
10444246635
-
Combination therapy with bosentan and sildenafil in idiopathic pulmonary arterial hypertension
-
DOI 10.1183/09031936.04.00051104
-
Hoeper, M.M., Faulenbach, C., Golpon, H., Winkler, J., Welte, T., Niedermeyer, J. Combination therapy with bosentan and sildenafil in idiopathic pulmonary arterial hypertension. Eur Respir J 2004, 24(6): 1007-10. (Pubitemid 39642293)
-
(2004)
European Respiratory Journal
, vol.24
, Issue.6
, pp. 1007-1010
-
-
Hoeper, M.M.1
Faulenbach, C.2
Golpon, H.3
Winkler, J.4
Welte, T.5
Niedermeyer, J.6
-
26
-
-
46449124591
-
Ambrisentan for the treatment of pulmonary arterial hypertension: Results of the ambrisentan in pulmonary arterial hypertension, randomized, double-blind, placebo-controlled, multicenter, efficacy (ARIES) study 1 and 2
-
Galie, N., Olschewski, H., Oudiz, R.J. et al. Ambrisentan for the treatment of pulmonary arterial hypertension: results of the ambrisentan in pulmonary arterial hypertension, randomized, double-blind, placebo-controlled, multicenter, efficacy (ARIES) study 1 and 2. Circulation 2008, 117(23): 3010-9.
-
(2008)
Circulation
, vol.117
, Issue.23
, pp. 3010-3019
-
-
Galie, N.1
Olschewski, H.2
Oudiz, R.J.3
-
27
-
-
70350708667
-
Long-term ambrisentan therapy for the treatment of pulmonary arterial hypertension
-
Oudiz, R.J., Galie, N., Olschewski, H. et al. Long-term ambrisentan therapy for the treatment of pulmonary arterial hypertension. J Am Coll Cardiol 2009, 54(21): 1971-81.
-
(2009)
J Am Coll Cardiol
, vol.54
, Issue.21
, pp. 1971-1981
-
-
Oudiz, R.J.1
Galie, N.2
Olschewski, H.3
-
28
-
-
75149115729
-
Long-term outcomes with ambrisentan monotherapy in pulmonary arterial hypertension
-
Blalock, S.E., Matulevicius, S., Mitchell, L.C. et al. Long-term outcomes with ambrisentan monotherapy in pulmonary arterial hypertension. J Card Fail 2010, 16(2): 121-7.
-
(2010)
J Card Fail
, vol.16
, Issue.2
, pp. 121-127
-
-
Blalock, S.E.1
Matulevicius, S.2
Mitchell, L.C.3
-
29
-
-
11144304239
-
A receptor antagonist sitaxsentan sodium, in a patient population with pulmonary arterial hypertension that meets traditional inclusion criteria of previous pulmonary arterial hypertension trials
-
DOI 10.1097/01.fjc.0000166207.74178.d0
-
Langleben, D., Brock, T., Dixon, R., Barst, R. STRIDE 1: effects of the selective ET(A) receptor antagonist, sitaxsentan sodium, in a patient population with pulmonary arterial hypertension that meets traditional inclusion criteria of previ- ous pulmonary arterial hypertension trials. J Cardiovasc Pharmacol 2004, 44 Suppl 1: S80-4. (Pubitemid 40039649)
-
(2004)
Journal of Cardiovascular Pharmacology
, vol.44
, Issue.SUPPL. 1
-
-
Langleben, D.1
Brock, T.2
Dixon, R.3
Barst, R.4
-
30
-
-
77953732287
-
Two-year follow-up of pulmonary arterial hypertension patients treated with sildenafil
-
Franchi, S.M., Barreto, A.C., Cicero, C., Castro, C.R., Ribeiro, Z.V., Lopes, A.A. [Two-year follow-up of pulmonary arterial hypertension patients treated with sildenafil]. Arq Bras Cardiol 2010, 94(5): 671-7.
-
(2010)
Arq Bras Cardiol
, vol.94
, Issue.5
, pp. 671-677
-
-
Franchi, S.M.1
Barreto, A.C.2
Cicero, C.3
Castro, C.R.4
Ribeiro, Z.V.5
Lopes, A.A.6
-
31
-
-
54549125950
-
Addition of sildenafil to long-term intravenous epoprostenol therapy in patients with pulmonary arterial hypertension: A randomized trial
-
Simonneau, G., Rubin, L.J., Galie, N. et al. Addition of sildenafil to long-term intravenous epoprostenol therapy in patients with pulmonary arterial hypertension: a randomized trial. Ann Intern Med 2008, 149(8): 521-30.
-
(2008)
Ann Intern Med
, vol.149
, Issue.8
, pp. 521-530
-
-
Simonneau, G.1
Rubin, L.J.2
Galie, N.3
-
32
-
-
70149121675
-
Acute hemodynamic effects of single-dose sildenafil when added to established bosentan therapy in patients with pulmonary arterial hypertension: Results of the COMPASS-1 study
-
Gruenig, E., Michelakis, E., Vachiery, J.L. et al. Acute hemodynamic effects of single-dose sildenafil when added to established bosentan therapy in patients with pulmonary arterial hypertension: results of the COMPASS-1 study. J Clin Pharmacol 2009, 49(11): 1343-52.
-
(2009)
J Clin Pharmacol
, vol.49
, Issue.11
, pp. 1343-1352
-
-
Gruenig, E.1
Michelakis, E.2
Vachiery, J.L.3
-
33
-
-
67649523052
-
Tadalafil therapy for pulmonary arterial hypertension
-
Galie, N., Brundage, B.H., Ghofrani, H.A. et al. Tadalafil therapy for pulmonary arterial hypertension. Circulation 2009, 119(22): 2894-903.
-
(2009)
Circulation
, vol.119
, Issue.22
, pp. 2894-2903
-
-
Galie, N.1
Brundage, B.H.2
Ghofrani, H.A.3
-
34
-
-
41849103027
-
Pharmacokinetic interaction between tadalafil and bosentan in healthy male subjects
-
DOI 10.1177/0091270008315315
-
Wrishko, R.E., Dingemanse, J., Yu, A., Darstein, C., Phillips, D.L., Mitchell, M.I. Pharmacokinetic interaction between tadalafil and bosentan in healthy male subjects. J Clin Pharmacol 2008, 48(5): 610-8. (Pubitemid 351503516)
-
(2008)
Journal of Clinical Pharmacology
, vol.48
, Issue.5
, pp. 610-618
-
-
Wrishko, R.E.1
Dingemanse, J.2
Yu, A.3
Darstein, C.4
Phillips, D.L.5
Mitchell, M.I.6
-
35
-
-
53849089139
-
Expression and function of soluble guanylate cyclase in pulmonary arterial hypertension
-
Schermuly, R.T., Stasch, J.P., Pullamsetti, S.S. et al. Expression and function of soluble guanylate cyclase in pulmonary arterial hypertension. Eur Respir J 2008, 32(4): 881-91.
-
(2008)
Eur Respir J
, vol.32
, Issue.4
, pp. 881-891
-
-
Schermuly, R.T.1
Stasch, J.P.2
Pullamsetti, S.S.3
-
36
-
-
77956664858
-
Riociguat for chronic thromboembolic pulmonary hypertension and pulmonary arterial hypertension: A phase II study
-
Ghofrani, H.A., Hoeper, M.M., Halank, M. et al. Riociguat for chronic thromboembolic pulmonary hypertension and pulmonary arterial hypertension: a phase II study. Eur Respir J 2010, 36(4): 792-9.
-
(2010)
Eur Respir J
, vol.36
, Issue.4
, pp. 792-799
-
-
Ghofrani, H.A.1
Hoeper, M.M.2
Halank, M.3
-
37
-
-
63849256355
-
First acute haemodynamic study of soluble guanylate cyclase stimulator riociguat in pulmonary hypertension
-
Grimminger, F., Weimann, G., Frey, R. et al. First acute haemodynamic study of soluble guanylate cyclase stimulator riociguat in pulmonary hypertension. Eur Respir J 2009, 33(4): 785-92.
-
(2009)
Eur Respir J
, vol.33
, Issue.4
, pp. 785-792
-
-
Grimminger, F.1
Weimann, G.2
Frey, R.3
-
38
-
-
69449088801
-
Vardenafil treatment for patients with pulmonary arterial hypertension: A multicentre, open-label study
-
Jing, Z.C., Jiang, X., Wu, B.X. et al. Vardenafil treatment for patients with pulmonary arterial hypertension: a multicentre, open-label study. Heart 2009, 95(18): 1531-6.
-
(2009)
Heart
, vol.95
, Issue.18
, pp. 1531-1536
-
-
Jing, Z.C.1
Jiang, X.2
Wu, B.X.3
-
39
-
-
36949037998
-
Pilot study of short-term effects of a novel long-acting oral beraprost in patients with pulmonary arterial hypertension
-
DOI 10.1253/circj.71.1829
-
Ikeda, D., Tsujino, I., Sakaue, S. et al. Pilot study of shortterm effects of a novel long-acting oral beraprost in patients with pulmonary arterial hypertension. Circ J 2007, 71(11): 1829-31. (Pubitemid 350240113)
-
(2007)
Circulation Journal
, vol.71
, Issue.11
, pp. 1829-1831
-
-
Ikeda, D.1
Tsujino, I.2
Sakaue, S.3
Ohira, H.4
Itoh, N.5
Kamigaki, M.6
Ishimaru, S.7
Atsumi, T.8
Nishimura, M.9
-
40
-
-
70349261340
-
Effects of long-acting beraprost sodium (TRK-100STP) in Japanese patients with pulmonary arterial hypertension
-
Kunieda, T., Nakanishi, N., Matsubara, H. et al. Effects of long-acting beraprost sodium (TRK-100STP) in Japanese patients with pulmonary arterial hypertension. Int Heart J 2009, 50(4): 513-29.
-
(2009)
Int Heart J
, vol.50
, Issue.4
, pp. 513-529
-
-
Kunieda, T.1
Nakanishi, N.2
Matsubara, H.3
-
41
-
-
53849102602
-
A long-acting and highly selective prostacyclin receptor agonist prodrug, 2-{4-[(5,6-diphenylpyrazin-2-yl)(isopropyl)- amino]butoxy}-N-(methylsulfonyl) acetamide (NS-304), ameliorates rat pulmonary hypertension with unique relaxant responses of its active form, {4-[(5,6-diphenylpyrazin-2- yl)(isopropyl)amino] butoxy}acetic acid (MRE-269), on rat pulmonary artery
-
Kuwano, K., Hashino, A., Noda, K., Kosugi, K., Kuwabara, K. A long-acting and highly selective prostacyclin receptor agonist prodrug, 2-{4-[(5,6-diphenylpyrazin-2-yl)(isopropyl)- amino]butoxy}-N-(methylsulfonyl) acetamide (NS-304), ameliorates rat pulmonary hypertension with unique relaxant responses of its active form, {4-[(5,6-diphenylpyrazin-2- yl)(isopropyl)amino] butoxy}acetic acid (MRE-269), on rat pulmonary artery. J Pharmacol Exp Ther 2008, 326(3): 691-9.
-
(2008)
J Pharmacol Exp Ther
, vol.326
, Issue.3
, pp. 691-699
-
-
Kuwano, K.1
Hashino, A.2
Noda, K.3
Kosugi, K.4
Kuwabara, K.5
-
42
-
-
57349133022
-
Pharmacology of macitentan, an orally active tissue-targeting dual endothelin receptor antagonist
-
Iglarz, M., Binkert, C., Morrison, K. et al. Pharmacology of macitentan, an orally active tissue-targeting dual endothelin receptor antagonist. J Pharmacol Exp Ther 2008, 327(3): 736-45.
-
(2008)
J Pharmacol Exp Ther
, vol.327
, Issue.3
, pp. 736-745
-
-
Iglarz, M.1
Binkert, C.2
Morrison, K.3
-
43
-
-
54949091985
-
Cicletanine for the treatment of pulmonary arterial hypertension
-
Waxman, A.B., Lawler, L., Cornett, G. Cicletanine for the treatment of pulmonary arterial hypertension. Arch Intern Med 2008, 168(19): 2164-6.
-
(2008)
Arch Intern Med
, vol.168
, Issue.19
, pp. 2164-2166
-
-
Waxman, A.B.1
Lawler, L.2
Cornett, G.3
-
44
-
-
68949132838
-
L-Citrulline ameliorates chronic hypoxia-induced pulmonary hypertension in newborn piglets
-
Ananthakrishnan, M., Barr, F.E., Summar, M.L. et al. L-Citrulline ameliorates chronic hypoxia-induced pulmonary hypertension in newborn piglets. Am J Physiol Lung Cell Mol Physiol 2009, 297(3): L506-11.
-
(2009)
Am J Physiol Lung Cell Mol Physiol
, vol.297
, Issue.3
-
-
Ananthakrishnan, M.1
Barr, F.E.2
Summar, M.L.3
-
45
-
-
57049129830
-
Long-term inhaled nitric oxide plus phosphodiesterase 5 inhibitors for severe pulmonary hypertension
-
Perez-Penate, G.M., Julia-Serda, G., Ojeda-Betancort, N. et al. Long-term inhaled nitric oxide plus phosphodiesterase 5 inhibitors for severe pulmonary hypertension. J Heart Lung Transplant 2008, 27(12): 1326-32.
-
(2008)
J Heart Lung Transplant
, vol.27
, Issue.12
, pp. 1326-1332
-
-
Perez-Penate, G.M.1
Julia-Serda, G.2
Ojeda-Betancort, N.3
-
46
-
-
0033826581
-
The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals
-
Kureishi, Y., Luo, Z., Shiojima, I. et al. The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals. Nat Med 2000, 6(9): 1004-10.
-
(2000)
Nat Med
, vol.6
, Issue.9
, pp. 1004-1010
-
-
Kureishi, Y.1
Luo, Z.2
Shiojima, I.3
-
47
-
-
65349171770
-
3-Hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors and phosphodiesterase type V inhibitors attenuate right ventricular pressure and remodeling in a rat model of pulmonary hypertension
-
Satoh, M., Satoh, A. 3-Hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors and phosphodiesterase type V inhibitors attenuate right ventricular pressure and remodeling in a rat model of pulmonary hypertension. J Pharm Pharm Sci 2008, 11(2): 118s-30s.
-
(2008)
J Pharm Pharm Sci
, vol.11
, Issue.2
-
-
Satoh, M.1
Satoh, A.2
-
48
-
-
70349649065
-
Simvastatin and sildenafil combine to attenuate pulmonary hypertension
-
Zhao, L., Sebkhi, A., Ali, O. et al. Simvastatin and sildenafil combine to attenuate pulmonary hypertension. Eur Respir J 2009, 34(4): 948-57.
-
(2009)
Eur Respir J
, vol.34
, Issue.4
, pp. 948-957
-
-
Zhao, L.1
Sebkhi, A.2
Ali, O.3
-
49
-
-
77953273837
-
Simvastatin as a treatment for pulmonary hypertension trial
-
Wilkins, M.R., Ali, O., Bradlow, W. et al. Simvastatin as a treatment for pulmonary hypertension trial. Am J Respir Crit Care Med 2010, 181(10): 1106-13.
-
(2010)
Am J Respir Crit Care Med
, vol.181
, Issue.10
, pp. 1106-1113
-
-
Wilkins, M.R.1
Ali, O.2
Bradlow, W.3
-
50
-
-
57149145794
-
Combined tyrosine and serine/threonine kinase inhibition by sorafenib prevents progression of experimental pulmonary hypertension and myocardial remodeling
-
Klein, M., Schermuly, R.T., Ellinghaus, P. et al. Combined tyrosine and serine/threonine kinase inhibition by sorafenib prevents progression of experimental pulmonary hypertension and myocardial remodeling. Circulation 2008, 118(20): 2081-90.
-
(2008)
Circulation
, vol.118
, Issue.20
, pp. 2081-2090
-
-
Klein, M.1
Schermuly, R.T.2
Ellinghaus, P.3
-
51
-
-
77957832881
-
Effective reduction of MCT-PAH by fasudil. Comparison with bosentan and sildenafil
-
Mouchaers, K.T., Schalij, I., de Boer, M.A. et al. Effective reduction of MCT-PAH by fasudil. Comparison with bosentan and sildenafil. Eur Respir J 2010, 36(4): 800-7.
-
(2010)
Eur Respir J
, vol.36
, Issue.4
, pp. 800-807
-
-
Mouchaers, K.T.1
Schalij, I.2
De Boer, M.A.3
-
52
-
-
38349096471
-
Gene transfer of endothelial nitric oxide synthase attenuates flow-induced pulmonary hypertension in rabbits
-
Zhang, F., Wu, S., Lu, X., Wang, M., Liu, M. Gene transfer of endothelial nitric oxide synthase attenuates flow-induced pulmonary hypertension in rabbits. Ann Thorac Surg 2008, 85(2): 581-5.
-
(2008)
Ann Thorac Surg
, vol.85
, Issue.2
, pp. 581-585
-
-
Zhang, F.1
Wu, S.2
Lu, X.3
Wang, M.4
Liu, M.5
-
53
-
-
77954948769
-
PRX-08066, a novel 5-hydroxytryptamine receptor 2B antagonist, reduces monocrotaline-induced pulmonary arterial hypertension and right ventricular hypertrophy in rats
-
Porvasnik, S.L., Germain, S., Embury, J. et al. PRX-08066, a novel 5-hydroxytryptamine receptor 2B antagonist, reduces monocrotaline-induced pulmonary arterial hypertension and right ventricular hypertrophy in rats. J Pharmacol Exp Ther 2010, 334(2): 364-72.
-
(2010)
J Pharmacol Exp Ther
, vol.334
, Issue.2
, pp. 364-372
-
-
Porvasnik, S.L.1
Germain, S.2
Embury, J.3
-
54
-
-
74249096822
-
In vivo effects of a combined 5-HT1B receptor/SERT antagonist in experimental pulmonary hypertension
-
Morecroft, I., Pang, L., Baranowska, M. et al. In vivo effects of a combined 5-HT1B receptor/SERT antagonist in experimental pulmonary hypertension. Cardiovasc Res 2010, 85(3): 593-603.
-
(2010)
Cardiovasc Res
, vol.85
, Issue.3
, pp. 593-603
-
-
Morecroft, I.1
Pang, L.2
Baranowska, M.3
-
55
-
-
20344365090
-
Serotonin transporter inhibition prevents and reverses monocrotaline- induced pulmonary hypertension in rats
-
DOI 10.1161/CIRCULATIONAHA.104.524926
-
Guignabert, C., Raffestin, B., Benferhat, R. et al. Serotonin transporter inhibition prevents and reverses monocrotaline-induced pulmonary hypertension in rats. Circulation 2005, 111(21): 2812-9. (Pubitemid 40791554)
-
(2005)
Circulation
, vol.111
, Issue.21
, pp. 2812-2819
-
-
Guignabert, C.1
Raffestin, B.2
Benferhat, R.3
Raoul, W.4
Zadigue, P.5
Rideau, D.6
Hamon, M.7
Adnot, S.8
Eddahibi, S.9
-
56
-
-
3142576948
-
Effect of single doses of SLV306, an inhibitor of both neutral endopeptidase and endothelin-converting enzyme, on pulmonary pressures in congestive heart failure
-
DOI 10.1016/j.amjcard.2004.03.074, PII S0002914904005223
-
Dickstein, K., De Voogd, H.J., Miric, M.P., Willenbrock, R., Mitrovic, V., Pacher, R., Koopman, P.A. Effect of single doses of SLV306, an inhibitor of both neutral endopeptidase and endothelin-converting enzyme, on pulmonary pressures in congestive heart failure. Am J Cardiol 2004, 94(2): 237-9. (Pubitemid 38902881)
-
(2004)
American Journal of Cardiology
, vol.94
, Issue.2
, pp. 237-239
-
-
Dickstein, K.1
De Voogd, H.J.2
Miric, M.P.3
Willenbrock, R.4
Mitrovic, V.5
Pacher, R.6
Koopman, P.A.7
-
57
-
-
70350439907
-
Allogenic stem cell therapy improves right ventricular function by improving lung pathology in rats with pulmonary hypertension
-
Umar, S., de Visser, Y.P., Steendijk, P. et al. Allogenic stem cell therapy improves right ventricular function by improving lung pathology in rats with pulmonary hypertension. Am J Physiol Heart Circ Physiol 2009, 297(5): H1606-16.
-
(2009)
Am J Physiol Heart Circ Physiol
, vol.297
, Issue.5
-
-
Umar, S.1
De Visser, Y.P.2
Steendijk, P.3
-
58
-
-
77952771680
-
Mesenchymal stem cell-based prostacyclin synthase gene therapy for pulmonary hypertension rats
-
Takemiya, K., Kai, H., Yasukawa, H., Tahara, N., Kato, S., Imaizumi, T. Mesenchymal stem cell-based prostacyclin synthase gene therapy for pulmonary hypertension rats. Basic Res Cardiol 2010, 105(3): 409-17.
-
(2010)
Basic Res Cardiol
, vol.105
, Issue.3
, pp. 409-417
-
-
Takemiya, K.1
Kai, H.2
Yasukawa, H.3
Tahara, N.4
Kato, S.5
Imaizumi, T.6
-
59
-
-
69549103334
-
Cost-utility of treatments for pulmonary arterial hypertension: A Markov state-transition decision analysis model
-
Garin, M.C., Clark, L., Chumney, E.C., Simpson, K.N., Highland, K.B. Cost-utility of treatments for pulmonary arterial hypertension: a Markov state-transition decision analysis model. Clin Drug Investig 2009, 29(10): 635-46.
-
(2009)
Clin Drug Investig
, vol.29
, Issue.10
, pp. 635-646
-
-
Garin, M.C.1
Clark, L.2
Chumney, E.C.3
Simpson, K.N.4
Highland, K.B.5
-
60
-
-
84878713370
-
Adcirca
-
May 13, Accessed July 28, 2010
-
Adcirca. Destination Rx, May 13, 2010. http://www.destinationrx. com/druginfo.aspx?drugName=Adcirca&drugID=40 941. Accessed July 28, 2010.
-
(2010)
Destination Rx
-
-
|