메뉴 건너뛰기




Volumn 5, Issue 2, 2010, Pages

Endothelial cell processing and alternatively spliced transcripts of factor VIII: Potential implications for coagulation cascades and pulmonary hypertension

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 8; CD31 ANTIGEN; VON WILLEBRAND FACTOR; ISOPROTEIN;

EID: 77949347401     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0009154     Document Type: Article
Times cited : (39)

References (48)
  • 1
    • 0242585716 scopus 로고    scopus 로고
    • Blood coagulation
    • Dahlbäck B (2000) Blood coagulation. Lancet 355: 1627-1632.
    • (2000) Lancet , vol.355 , pp. 1627-1632
    • Dahlbäck, B.1
  • 3
    • 0035822038 scopus 로고    scopus 로고
    • The hemophilias-from royal genes to gene therapy
    • Mannucci PM, Tuddenham EGD (2001) The hemophilias-from royal genes to gene therapy. N Engl J Med 344: 1773-1779.
    • (2001) N Engl J Med , vol.344 , pp. 1773-1779
    • Mannucci, P.M.1    Tuddenham, E.G.D.2
  • 5
    • 0041317700 scopus 로고    scopus 로고
    • The risk of recurrent venous thromboembolism: The Austrian study on recurrent venous thromboembolism
    • Kyrle PA, Eichinger S (2003) The risk of recurrent venous thromboembolism: the Austrian study on recurrent venous thromboembolism. Wien Klin Wochenschr 115: 471-474.
    • (2003) Wien Klin Wochenschr , vol.115 , pp. 471-474
    • Kyrle, P.A.1    Eichinger, S.2
  • 6
    • 23044436561 scopus 로고    scopus 로고
    • House of Commons Select Committee on Health Second report , Available
    • House of Commons Select Committee on Health Second report (2005) The prevention of venous thromboembolism in hospitalised patients. Available: http://www.publications.parliament.uk/pa/cm200405/cmselect/cmhealth/99/9906.htm.
    • (2005) The prevention of venous thromboembolism in hospitalised patients
  • 7
    • 70349634397 scopus 로고    scopus 로고
    • Guidelines for the diagnosis and treatment of pulmonary hypertension
    • Galie N, Hoeper MM, Humbert M, Torbicki A, Vachiery JL, et al. (2009) Guidelines for the diagnosis and treatment of pulmonary hypertension. Eur Respir J 34: 1219-63.
    • (2009) Eur Respir J , vol.34 , pp. 1219-1263
    • Galie, N.1    Hoeper, M.M.2    Humbert, M.3    Torbicki, A.4    Vachiery, J.L.5
  • 8
    • 2442643903 scopus 로고    scopus 로고
    • Incidence of chronic thromboembolic pulmonary hypertension after pulmonary embolism
    • Pengo V, Lensing AWA, Prins MH, Marchiori A, Davidson BL, et al. (2004) Incidence of chronic thromboembolic pulmonary hypertension after pulmonary embolism. New Engl J Med 350: 2257-2264.
    • (2004) New Engl J Med , vol.350 , pp. 2257-2264
    • Pengo, V.1    Lensing, A.W.A.2    Prins, M.H.3    Marchiori, A.4    Davidson, B.L.5
  • 9
    • 10744225650 scopus 로고    scopus 로고
    • High prevalence of elevated clotting factor VIII in chronic thromboembolic pulmonary hypertension
    • Bonderman D, Turecek PL, Jakowitsch J, Welterman A, Adlbrecht C, et al. (2003) High prevalence of elevated clotting factor VIII in chronic thromboembolic pulmonary hypertension. Thromb Haemost 90: 372-376.
    • (2003) Thromb Haemost , vol.90 , pp. 372-376
    • Bonderman, D.1    Turecek, P.L.2    Jakowitsch, J.3    Welterman, A.4    Adlbrecht, C.5
  • 11
    • 0024597022 scopus 로고
    • Effect of von Willebrand factor coexpression on the synthesis and secretion of factor VIII in chinese hamster ovary cells
    • Kaufman RJ, Wasley LC, Davies MV, Wise RJ, Israel DI, et al. (1989) Effect of von Willebrand factor coexpression on the synthesis and secretion of factor VIII in chinese hamster ovary cells. Mol Cell Biol 9: 1233-1242.
    • (1989) Mol Cell Biol , vol.9 , pp. 1233-1242
    • Kaufman, R.J.1    Wasley, L.C.2    Davies, M.V.3    Wise, R.J.4    Israel, D.I.5
  • 13
    • 0034839787 scopus 로고    scopus 로고
    • Tissue distribution of factor VIII gene expression in vivo - a closer look
    • Hollestelle MJ, Thinnes T, Crain K, Stiko A, Kruijt JK, et al. (2001) Tissue distribution of factor VIII gene expression in vivo - a closer look. Thromb Haemost 86: 855-861.
    • (2001) Thromb Haemost , vol.86 , pp. 855-861
    • Hollestelle, M.J.1    Thinnes, T.2    Crain, K.3    Stiko, A.4    Kruijt, J.K.5
  • 14
    • 0015058043 scopus 로고
    • Plasma factor VIII synthesis and control as revealed by canine organ transplantation
    • Webster WP, Zukoski CF, Hutchin P, Reddick RL, Mandel SR, et al. (1971) Plasma factor VIII synthesis and control as revealed by canine organ transplantation. Am J Physiol 220: 1147-1154.
    • (1971) Am J Physiol , vol.220 , pp. 1147-1154
    • Webster, W.P.1    Zukoski, C.F.2    Hutchin, P.3    Reddick, R.L.4    Mandel, S.R.5
  • 15
    • 36049038657 scopus 로고    scopus 로고
    • Elevated factor VIII in hereditary haemorrhagic telangiectasia (HHT): Association with venous thromboembolism
    • Shovlin CL, Sulainam NL, Govani FS, Jackson JE, Begbie ME (2007) Elevated factor VIII in hereditary haemorrhagic telangiectasia (HHT): association with venous thromboembolism. Thromb Haemost 98: 1031-1039.
    • (2007) Thromb Haemost , vol.98 , pp. 1031-1039
    • Shovlin, C.L.1    Sulainam, N.L.2    Govani, F.S.3    Jackson, J.E.4    Begbie, M.E.5
  • 16
    • 40649111657 scopus 로고    scopus 로고
    • Primary determinants of ischaemic stroke/brain abscess risks are independent of severity of pulmonary arteriovenous malformations in hereditary haemorrhagic telangiectasia
    • Shovlin CL, Jackson JE, Bamford KB, Jenkins IH, Benjamin AR, et al. (2008) Primary determinants of ischaemic stroke/brain abscess risks are independent of severity of pulmonary arteriovenous malformations in hereditary haemorrhagic telangiectasia. Thorax 63: 259-266.
    • (2008) Thorax , vol.63 , pp. 259-266
    • Shovlin, C.L.1    Jackson, J.E.2    Bamford, K.B.3    Jenkins, I.H.4    Benjamin, A.R.5
  • 17
    • 52749098193 scopus 로고    scopus 로고
    • Embolisation of pulmonary arteriovenous malformations: No consistent effect on pulmonary artery pressure
    • Shovlin CL, Tighe HC, Davies RJ, Gibbs JSR, Jackson JE (2008) Embolisation of pulmonary arteriovenous malformations: no consistent effect on pulmonary artery pressure. Eur Resp J 32: 162-169.
    • (2008) Eur Resp J , vol.32 , pp. 162-169
    • Shovlin, C.L.1    Tighe, H.C.2    Davies, R.J.3    Gibbs, J.S.R.4    Jackson, J.E.5
  • 18
    • 0015609534 scopus 로고
    • Morphological basis of alveolar-capillary gas exchange
    • Weibel ER (1973) Morphological basis of alveolar-capillary gas exchange. Physiological Reviews 53: 419-495.
    • (1973) Physiological Reviews , vol.53 , pp. 419-495
    • Weibel, E.R.1
  • 19
  • 20
    • 28244484911 scopus 로고    scopus 로고
    • The promise and challenges of bioengineered recombinant clotting factors
    • Pipe SW (2005) The promise and challenges of bioengineered recombinant clotting factors. J Thromb Haemost 3: 1692-1701.
    • (2005) J Thromb Haemost , vol.3 , pp. 1692-1701
    • Pipe, S.W.1
  • 21
    • 3543036376 scopus 로고    scopus 로고
    • Confocal microscopy analysis of native full length and B-domain deleted coagulation factor VIII trafficking in mammalian cells
    • Becker S, Simpson JC, Pepperkok R, Heinz S, Herder C, et al. (2004) Confocal microscopy analysis of native full length and B-domain deleted coagulation factor VIII trafficking in mammalian cells. Thromb Haemost 92: 23-35.
    • (2004) Thromb Haemost , vol.92 , pp. 23-35
    • Becker, S.1    Simpson, J.C.2    Pepperkok, R.3    Heinz, S.4    Herder, C.5
  • 22
    • 70449570719 scopus 로고    scopus 로고
    • Functional roles of the factor VIII B domain
    • Pipe SW (2009) Functional roles of the factor VIII B domain. Hemophilia 15: 1187-96.
    • (2009) Hemophilia , vol.15 , pp. 1187-1196
    • Pipe, S.W.1
  • 23
    • 0022363126 scopus 로고
    • Purification of human factor VIII:C and its characterisation by Western Blotting using monoclonal antibodies
    • Rotblat F, O'Brien DP, O'Brien FJ, Goodall AH, Tuddenham EG (1985) Purification of human factor VIII:C and its characterisation by Western Blotting using monoclonal antibodies. Biochemistry 24: 4294-4300.
    • (1985) Biochemistry , vol.24 , pp. 4294-4300
    • Rotblat, F.1    O'Brien, D.P.2    O'Brien, F.J.3    Goodall, A.H.4    Tuddenham, E.G.5
  • 25
    • 33846057724 scopus 로고    scopus 로고
    • NCBI reference sequences (RefSeq): A curated non-redundant sequence database of genomes, transcripts and proteins
    • Pruitt KD, Tatusova T, Maglott DR (2007) NCBI reference sequences (RefSeq): a curated non-redundant sequence database of genomes, transcripts and proteins. Nucleic Acids Res 35: D61-65.
    • (2007) Nucleic Acids Res , vol.35
    • Pruitt, K.D.1    Tatusova, T.2    Maglott, D.R.3
  • 26
    • 77949360172 scopus 로고    scopus 로고
    • Available
    • ExonMine. Available: http://www.imm.fm.ul.pt/exonmine/.
    • ExonMine
  • 27
    • 0036226603 scopus 로고    scopus 로고
    • BLAT-the BLAST-like alignment tool
    • Kent WJ (2002) BLAT-the BLAST-like alignment tool. Genome Res 12: 656-664.
    • (2002) Genome Res , vol.12 , pp. 656-664
    • Kent, W.J.1
  • 29
    • 77949366350 scopus 로고    scopus 로고
    • Available
    • UCSC Genome Browser. Available: http://genome.ucsc.edu/.
  • 31
    • 0000534956 scopus 로고
    • New cytoplasmic components in arterial endothelia
    • Weibel ER, Palade GE (1964) New cytoplasmic components in arterial endothelia. J Cell Biol 23: 101-112.
    • (1964) J Cell Biol , vol.23 , pp. 101-112
    • Weibel, E.R.1    Palade, G.E.2
  • 32
    • 0028977985 scopus 로고
    • cis-Acting elements and transcription factors involved in the promoter activity of the human Factor VIII gene
    • Figueiredo MS, Brownlee GG (1995) cis-Acting elements and transcription factors involved in the promoter activity of the human Factor VIII gene. J Biol Chem 20: 11828-11838.
    • (1995) J Biol Chem , vol.20 , pp. 11828-11838
    • Figueiredo, M.S.1    Brownlee, G.G.2
  • 33
    • 0029963548 scopus 로고    scopus 로고
    • Role of the liver-enriched transcription factor hepatocyte nuclear factor 1 in transcriptional regulation of the Factor VIII gene
    • McGlynn LK, Mueller CR, Begbie M, Notley CR, Lillicrap D (1996) Role of the liver-enriched transcription factor hepatocyte nuclear factor 1 in transcriptional regulation of the Factor VIII gene. Mol Cell Biol 16: 1936-1945.
    • (1996) Mol Cell Biol , vol.16 , pp. 1936-1945
    • McGlynn, L.K.1    Mueller, C.R.2    Begbie, M.3    Notley, C.R.4    Lillicrap, D.5
  • 34
    • 0015905229 scopus 로고
    • Synthesis of antihemophilic factor antigen by cultured human endothelial cells
    • Jaffe EA, Hoyer LW, Nachman RL (1973) Synthesis of antihemophilic factor antigen by cultured human endothelial cells. J Clin Invest 52: 2757-2764.
    • (1973) J Clin Invest , vol.52 , pp. 2757-2764
    • Jaffe, E.A.1    Hoyer, L.W.2    Nachman, R.L.3
  • 35
    • 0016409316 scopus 로고
    • Synthesis of factor VIII antigen by cultured human endothelial cells
    • Jaffe EA (1975) Synthesis of factor VIII antigen by cultured human endothelial cells. Ann N Y Acad Sci 240: 62-69.
    • (1975) Ann N Y Acad Sci , vol.240 , pp. 62-69
    • Jaffe, E.A.1
  • 36
    • 0020345886 scopus 로고
    • Synthesis of factor VIII by endothelial cells
    • Jaffe EA (1982) Synthesis of factor VIII by endothelial cells. Ann N Y Acad Sci 401: 163-170.
    • (1982) Ann N Y Acad Sci , vol.401 , pp. 163-170
    • Jaffe, E.A.1
  • 37
    • 35449008181 scopus 로고    scopus 로고
    • Requirements for cellular co-trafficking of factor VIII and von Willebrand factor to Weibel-Palade bodies
    • van den Biggelaar M, Bierings R, Storm G, Voorberg J, Mertens K (2007) Requirements for cellular co-trafficking of factor VIII and von Willebrand factor to Weibel-Palade bodies. J Thromb Haemost 5: 2235-42.
    • (2007) J Thromb Haemost , vol.5 , pp. 2235-2242
    • van den Biggelaar, M.1    Bierings, R.2    Storm, G.3    Voorberg, J.4    Mertens, K.5
  • 39
    • 0023845971 scopus 로고
    • Fibrinolytic and haemostatic responses to desamino-D-arginine vasopressin (DDAVP) administered by intravenous and subcutaneous routes in healthy subjects
    • MacGregor IR, Roberts EM, Prowse CV, Broomhead AF, Ozolins M, et al. (1988) Fibrinolytic and haemostatic responses to desamino-D-arginine vasopressin (DDAVP) administered by intravenous and subcutaneous routes in healthy subjects. Thromb Haemost 59: 34-39.
    • (1988) Thromb Haemost , vol.59 , pp. 34-39
    • MacGregor, I.R.1    Roberts, E.M.2    Prowse, C.V.3    Broomhead, A.F.4    Ozolins, M.5
  • 40
    • 33748781232 scopus 로고    scopus 로고
    • Controversies, uncertainties and future research on the treatment of chronic thromboembolic pulmonary hypertension
    • Peacock A, Simonneau G, Rubin L (2006) Controversies, uncertainties and future research on the treatment of chronic thromboembolic pulmonary hypertension. Proc Am Thorac Soc 3: 608-614.
    • (2006) Proc Am Thorac Soc , vol.3 , pp. 608-614
    • Peacock, A.1    Simonneau, G.2    Rubin, L.3
  • 42
    • 41849090451 scopus 로고    scopus 로고
    • Persistent factor VIII-dependent factor X activation on endothelial cells is independent of von Willebrand factor
    • Brinkman HJ, van Mourik JA, Mertens K (2008) Persistent factor VIII-dependent factor X activation on endothelial cells is independent of von Willebrand factor. Blood Coagul Fibrinolysis 19: 190-196.
    • (2008) Blood Coagul Fibrinolysis , vol.19 , pp. 190-196
    • Brinkman, H.J.1    van Mourik, J.A.2    Mertens, K.3
  • 43
    • 0023918719 scopus 로고
    • Synthesis, processing and secretion of recombinant human factor VIII expressed in mammalian cells
    • Kaufman RJ, Wasley LC, Dorner AJ (1988) Synthesis, processing and secretion of recombinant human factor VIII expressed in mammalian cells. J Biol Chem 263: 6352-6362.
    • (1988) J Biol Chem , vol.263 , pp. 6352-6362
    • Kaufman, R.J.1    Wasley, L.C.2    Dorner, A.J.3
  • 44
    • 33745899048 scopus 로고    scopus 로고
    • Alternative splicing: New insights from global analyses
    • Blencowe BJ (2006) Alternative splicing: new insights from global analyses. Cell 126: 37-47.
    • (2006) Cell , vol.126 , pp. 37-47
    • Blencowe, B.J.1
  • 45
    • 0028917478 scopus 로고
    • Expression of the blood-clotting factor-VIII cDNA is repressed by a transcriptional silencer located in its coding region
    • Hoeben RC, Fallaux FJ, Cramer SJ, van den Wollenberg DJM, van Ormondt H, et al. (1995) Expression of the blood-clotting factor-VIII cDNA is repressed by a transcriptional silencer located in its coding region. Blood 85: 2447-2454.
    • (1995) Blood , vol.85 , pp. 2447-2454
    • Hoeben, R.C.1    Fallaux, F.J.2    Cramer, S.J.3    van den Wollenberg, D.J.M.4    van Ormondt, H.5
  • 46
    • 0034905074 scopus 로고    scopus 로고
    • A factor VIII minigene comprising the truncated intron I of factor IX highly improves the in vitro production of factor VIII
    • Plantier JL, Rodriguez MH, Enjolras N, Attali O, Négrier C (2001) A factor VIII minigene comprising the truncated intron I of factor IX highly improves the in vitro production of factor VIII. Thromb Haemost 86: 596-603.
    • (2001) Thromb Haemost , vol.86 , pp. 596-603
    • Plantier, J.L.1    Rodriguez, M.H.2    Enjolras, N.3    Attali, O.4    Négrier, C.5
  • 47
    • 26444593981 scopus 로고    scopus 로고
    • Evidence of functional selection pressure for alternative splicing events that accelerate evolution of protein subsequences
    • Xing Y, Lee CJ (2005) Evidence of functional selection pressure for alternative splicing events that accelerate evolution of protein subsequences. Proc Natl Acad Sci U S A 102: 13526-13531.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 13526-13531
    • Xing, Y.1    Lee, C.J.2
  • 48
    • 14644420971 scopus 로고    scopus 로고
    • Gene conversion and evolution of Xq28 duplicons involved in recurring inversions causing severe haemophilia A
    • Bagnall RD, Ayres KL, Green PM, Gianelli F (2005) Gene conversion and evolution of Xq28 duplicons involved in recurring inversions causing severe haemophilia A. Genome Research 15: 214-223.
    • (2005) Genome Research , vol.15 , pp. 214-223
    • Bagnall, R.D.1    Ayres, K.L.2    Green, P.M.3    Gianelli, F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.