Losartan attenuates chronic cigarette smoke exposure-induced pulmonary arterial hypertension in rats: Possible involvement of angiotensin-converting enzyme-2

Toxicology and Applied Pharmacology

Volumn 245, Issue 1, 2010, Pages 100-107

  Han, Su Xia ^a   He, Guang Ming ^a   Wang, Tao ^a   Chen, Lei ^a   Ning, Yun Ye ^a   Luo, Feng ^a   An, Jin ^a   Yang, Ting ^a   Dong, Jia Jia ^a   Liao, Zeng lin ^a   Xu, Dan ^a   Wen, Fu Qiang ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Angiotensin converting enzyme 2; Cigarette smoke; Cigarette smoke extract; Losartan; Pulmonary arterial hypertension; Pulmonary vascular remodeling

Indexed keywords

ANGIOTENSIN CONVERTING ENZYME 2; ANGIOTENSIN II; CIGARETTE SMOKE; LOSARTAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIHYPERTENSIVE ACTIVITY; ARTERIAL WALL THICKNESS; ARTICLE; CELL CULTURE; CELL PROLIFERATION; CIGARETTE SMOKING; CONTROLLED STUDY; ENZYME INHIBITION; HEART RIGHT VENTRICLE PRESSURE; IN VITRO STUDY; IN VIVO STUDY; LONG TERM EXPOSURE; MALE; NONHUMAN; PULMONARY HYPERTENSION; RAT; SMOOTH MUSCLE FIBER; SYSTOLIC BLOOD PRESSURE;

AIR POLLUTANTS; ANIMALS; ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; HEART VENTRICLES; HYPERTENSION, PULMONARY; INHALATION EXPOSURE; LOSARTAN; MALE; PEPTIDYL-DIPEPTIDASE A; PULMONARY ARTERY; RATS; RATS, SPRAGUE-DAWLEY; RENIN-ANGIOTENSIN SYSTEM; SMOKING;

RATTUS;

EID: 77952543051     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2010.02.009     Document Type: Article

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