메뉴 건너뛰기




Volumn 93, Issue 2, 2012, Pages 148-156

Transforming growth factor-β enhances invasion and metastasis in Ras-transfected human malignant epidermal keratinocytes

Author keywords

Invasion; Isoform; Keratinocytes; SCC; TGF

Indexed keywords

RAS PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; TUMOR SUPPRESSOR PROTEIN;

EID: 84858211273     PISSN: 09599673     EISSN: 13652613     Source Type: Journal    
DOI: 10.1111/j.1365-2613.2011.00806.x     Document Type: Article
Times cited : (19)

References (28)
  • 1
    • 63049136592 scopus 로고    scopus 로고
    • A mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis
    • Adorno M., Cordenonsi M., Montagner M. et al. (2009) A mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis. Cell 137, 87-98.
    • (2009) Cell , vol.137 , pp. 87-98
    • Adorno, M.1    Cordenonsi, M.2    Montagner, M.3
  • 2
    • 33747889602 scopus 로고    scopus 로고
    • A novel functional polymorphism in the transforming growth factor-β2 gene promoter and tumour progression in breast cancer
    • Beisner J., Buck M.B., Fritz P. et al. (2006) A novel functional polymorphism in the transforming growth factor-β2 gene promoter and tumour progression in breast cancer. Cancer Res. 66, 7554-7561.
    • (2006) Cancer Res. , vol.66 , pp. 7554-7561
    • Beisner, J.1    Buck, M.B.2    Fritz, P.3
  • 3
    • 0030598681 scopus 로고    scopus 로고
    • TGFbeta1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice
    • Cui W., Fowlis D.J., Bryson S. et al. (1996) TGFbeta1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice. Cell 86, 531-542.
    • (1996) Cell , vol.86 , pp. 531-542
    • Cui, W.1    Fowlis, D.J.2    Bryson, S.3
  • 4
    • 0030798673 scopus 로고    scopus 로고
    • Overexpression of autocrine TGF-β1 suppresses the growth of spindle epithelial cells in vitro and in vivo in the rat 4-NQO model of oral carcinogenesis
    • Davies M., Prime S.S., Stone A.M. et al. (1997) Overexpression of autocrine TGF-β1 suppresses the growth of spindle epithelial cells in vitro and in vivo in the rat 4-NQO model of oral carcinogenesis. Int. J. Cancer 73, 68-74.
    • (1997) Int. J. Cancer , vol.73 , pp. 68-74
    • Davies, M.1    Prime, S.S.2    Stone, A.M.3
  • 5
    • 26444560222 scopus 로고    scopus 로고
    • Induction of an epithelial to mesenchymal transition in human immortal and malignant keratinocytes by TGF-β1 involves MAPK, Smad and AP-1 signalling pathways
    • Davies M., Robinson M., Smith E., Huntley S., Prime S., Paterson I. (2005) Induction of an epithelial to mesenchymal transition in human immortal and malignant keratinocytes by TGF-β1 involves MAPK, Smad and AP-1 signalling pathways. J. Cell. Biochem. 95, 918-931.
    • (2005) J. Cell. Biochem. , vol.95 , pp. 918-931
    • Davies, M.1    Robinson, M.2    Smith, E.3    Huntley, S.4    Prime, S.5    Paterson, I.6
  • 6
    • 0029784956 scopus 로고    scopus 로고
    • Dysregulation of autocrine TGF-β isoform production and ligand responses in tumour-derived and Ha-ras-transfected keratinocytes and fibroblasts
    • Fahey M.S., Paterson I.C., Stone A. et al. (1996) Dysregulation of autocrine TGF-β isoform production and ligand responses in tumour-derived and Ha-ras-transfected keratinocytes and fibroblasts. Br. J. Cancer 74, 1074-1080.
    • (1996) Br. J. Cancer , vol.74 , pp. 1074-1080
    • Fahey, M.S.1    Paterson, I.C.2    Stone, A.3
  • 7
    • 0031728635 scopus 로고    scopus 로고
    • Multiple stages and genetic alterations in immortalization, malignant transformation, and tumour progression of human skin keratinocytes
    • Fusenig N.E. & Boukamp P. (1998) Multiple stages and genetic alterations in immortalization, malignant transformation, and tumour progression of human skin keratinocytes. Mol. Carcinog. 23, 144-158.
    • (1998) Mol. Carcinog. , vol.23 , pp. 144-158
    • Fusenig, N.E.1    Boukamp, P.2
  • 8
    • 77956893106 scopus 로고    scopus 로고
    • TGF-β inhibits metastasis in late stage human squamous cell carcinoma of the skin by a mechanism that does not involve Id1
    • Ganapathy A., Paterson I.C., Prime S.S. et al. (2010) TGF-β inhibits metastasis in late stage human squamous cell carcinoma of the skin by a mechanism that does not involve Id1. Cancer Lett. 298, 107-118.
    • (2010) Cancer Lett. , vol.298 , pp. 107-118
    • Ganapathy, A.1    Paterson, I.C.2    Prime, S.S.3
  • 9
    • 0034106998 scopus 로고    scopus 로고
    • TGF-beta isoforms are differentially expressed in increasing malignant grades of HaCaT keratinocytes, suggesting separate roles in skin carcinogenesis
    • Gold L.I., Jussila T., Fusenig N.E., Stenbäck F. (2000) TGF-beta isoforms are differentially expressed in increasing malignant grades of HaCaT keratinocytes, suggesting separate roles in skin carcinogenesis. J. Pathol. 190, 579-588.
    • (2000) J. Pathol. , vol.190 , pp. 579-588
    • Gold, L.I.1    Jussila, T.2    Fusenig, N.E.3    Stenbäck, F.4
  • 10
    • 0024816337 scopus 로고
    • Human transforming growth factor-beta 3: recombinant expression, purification, and biological activities in comparison with transforming growth factors-beta 1 and -beta 2
    • Graycar J.L., Miller D.A., Arrick B.A., Lyons R.M., Moses H.L., Derynck R. (1989) Human transforming growth factor-beta 3: recombinant expression, purification, and biological activities in comparison with transforming growth factors-beta 1 and -beta 2. Mol. Endocrinol. 3, 1977-1986.
    • (1989) Mol. Endocrinol. , vol.3 , pp. 1977-1986
    • Graycar, J.L.1    Miller, D.A.2    Arrick, B.A.3    Lyons, R.M.4    Moses, H.L.5    Derynck, R.6
  • 11
    • 22144490495 scopus 로고    scopus 로고
    • Distinct mechanisms of TGF-β1-mediated epithelial-to-mesenchymal transition and metastasis during skin carcinogenesis
    • Han G., Lu S.-L., Li A.G. et al. (2005) Distinct mechanisms of TGF-β1-mediated epithelial-to-mesenchymal transition and metastasis during skin carcinogenesis. J. Clin. Invest. 115, 1714-1723.
    • (2005) J. Clin. Invest. , vol.115 , pp. 1714-1723
    • Han, G.1    Lu, S.-L.2    Li, A.G.3
  • 12
    • 77955295090 scopus 로고    scopus 로고
    • Epigenetic downregulation of human disabled homolog 2 switches TGF-beta from a tumor suppressor to a tumor promoter
    • Hannigan A., Smith P., Kalna G. et al. (2010) Epigenetic downregulation of human disabled homolog 2 switches TGF-beta from a tumor suppressor to a tumor promoter. J. Clin. Invest. 120, 2842-2857.
    • (2010) J. Clin. Invest. , vol.120 , pp. 2842-2857
    • Hannigan, A.1    Smith, P.2    Kalna, G.3
  • 13
    • 63749105896 scopus 로고    scopus 로고
    • Mechanisms of TGF-β signaling to growth arrest, apoptosis and epithelial-mesenchymal transition
    • Heldin C.H., Landstrom M., Moustaks A. (2009) Mechanisms of TGF-β signaling to growth arrest, apoptosis and epithelial-mesenchymal transition. Curr. Opin. Cell Biol. 21, 166-176.
    • (2009) Curr. Opin. Cell Biol. , vol.21 , pp. 166-176
    • Heldin, C.H.1    Landstrom, M.2    Moustaks, A.3
  • 14
    • 77950595599 scopus 로고    scopus 로고
    • Targeting the transforming growth factor-beta signalling pathway in metastatic cancer
    • Korpal M. & Kang Y. (2010) Targeting the transforming growth factor-beta signalling pathway in metastatic cancer. Eur. J. Cancer 46, 1232-1240.
    • (2010) Eur. J. Cancer , vol.46 , pp. 1232-1240
    • Korpal, M.1    Kang, Y.2
  • 16
    • 34548386720 scopus 로고    scopus 로고
    • TGF-beta activates Erk MAP kinase signalling through direct phosphorylation of ShcA
    • Lee M.K., Pardoux C., Hall M.C. et al. (2007) TGF-beta activates Erk MAP kinase signalling through direct phosphorylation of ShcA. EMBO J. 26, 3957-3967.
    • (2007) EMBO J. , vol.26 , pp. 3957-3967
    • Lee, M.K.1    Pardoux, C.2    Hall, M.C.3
  • 17
    • 0031908807 scopus 로고    scopus 로고
    • TGF-beta knockout and dominant-negative transgenic mice
    • Letterio J.J. & Bottinger E.P. (1998) TGF-beta knockout and dominant-negative transgenic mice. Miner. Electrolyte Metab. 24, 161-167.
    • (1998) Miner. Electrolyte Metab. , vol.24 , pp. 161-167
    • Letterio, J.J.1    Bottinger, E.P.2
  • 18
    • 84858185339 scopus 로고    scopus 로고
    • TGF-β in cancer
    • Massague J. (2008) TGF-β in cancer. Cell 134, 220-227.
    • (2008) Cell , vol.134 , pp. 220-227
    • Massague, J.1
  • 19
    • 78649982907 scopus 로고    scopus 로고
    • The dynamic roles of TGF-β in cancer
    • Meulmeester E. & ten Dijke P. (2011) The dynamic roles of TGF-β in cancer. J. Pathol. 223, 205-218.
    • (2011) J. Pathol. , vol.223 , pp. 205-218
    • Meulmeester, E.1    ten Dijke, P.2
  • 20
    • 14944357291 scopus 로고    scopus 로고
    • Development of a quantitative method to analyse tumorcell invasion in organotypic culture
    • Nystrom M.L., Thomas G.J., Hart I.R., Stone M., McKenzie I.C., Marshall J.F. (2005) Development of a quantitative method to analyse tumorcell invasion in organotypic culture. J. Pathol. 205, 468-475.
    • (2005) J. Pathol. , vol.205 , pp. 468-475
    • Nystrom, M.L.1    Thomas, G.J.2    Hart, I.R.3    Stone, M.4    McKenzie, I.C.5    Marshall, J.F.6
  • 21
    • 0026326375 scopus 로고
    • Immunohistochemical localization of TGF-β1, TGF-β2 and TGF-β3 in the mouse embryo: expression patterns suggest multiple roles during embryonic development
    • Pelton R.W., Saxena B., Jones M., Moses H.L., Gold L.I. (1991) Immunohistochemical localization of TGF-β1, TGF-β2 and TGF-β3 in the mouse embryo: expression patterns suggest multiple roles during embryonic development. J. Cell Biol. 115, 1091-1105.
    • (1991) J. Cell Biol. , vol.115 , pp. 1091-1105
    • Pelton, R.W.1    Saxena, B.2    Jones, M.3    Moses, H.L.4    Gold, L.I.5
  • 22
    • 0031817391 scopus 로고    scopus 로고
    • Transforming growth factor beta is essential for spindle cell conversion of mouse skin carcinoma in vivo: implications for tumor invasion
    • Portella G., Cumming S.A., Liddell J. et al. (1998) Transforming growth factor beta is essential for spindle cell conversion of mouse skin carcinoma in vivo: implications for tumor invasion. Cell Growth Differ. 9, 393-404.
    • (1998) Cell Growth Differ. , vol.9 , pp. 393-404
    • Portella, G.1    Cumming, S.A.2    Liddell, J.3
  • 23
    • 70450198396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and disease
    • Thiery J.P., Acloque H., Huang R.Y., Nieto M.A. (2009) Epithelial-mesenchymal transitions in development and disease. Cell 39, 871-890.
    • (2009) Cell , vol.39 , pp. 871-890
    • Thiery, J.P.1    Acloque, H.2    Huang, R.Y.3    Nieto, M.A.4
  • 24
    • 0037012009 scopus 로고    scopus 로고
    • Consequences of altered TGF-β expression and responsiveness in breast cancer: evidence for autocrine and paracrine effects
    • Tobin S.W., Douville K., Benbow U., Brinckerhoff C.E., Memoli V.A., Arrick B.A. (2002) Consequences of altered TGF-β expression and responsiveness in breast cancer: evidence for autocrine and paracrine effects. Oncogene 21, 108-118.
    • (2002) Oncogene , vol.21 , pp. 108-118
    • Tobin, S.W.1    Douville, K.2    Benbow, U.3    Brinckerhoff, C.E.4    Memoli, V.A.5    Arrick, B.A.6
  • 25
    • 11144357377 scopus 로고    scopus 로고
    • The potential role of TGFβ1, TGFβ2, and TGFβ3 protein expression in colorectal carcinomas
    • Tsamandas A.C., Kardamakis D., Ravazoula P. et al. (2004) The potential role of TGFβ1, TGFβ2, and TGFβ3 protein expression in colorectal carcinomas. Strahlenther. Onkol. 180, 201-208.
    • (2004) Strahlenther. Onkol. , vol.180 , pp. 201-208
    • Tsamandas, A.C.1    Kardamakis, D.2    Ravazoula, P.3
  • 26
    • 34047262040 scopus 로고    scopus 로고
    • TGF-β1, TGF-β2, and TGFβ3 protein expression in gastric ccarcinomas: correlation with prognostic factors and patient survival
    • Vagenas K., Spyropoulos C., Gavala V., Tsmandas A.C. (2007) TGF-β1, TGF-β2, and TGFβ3 protein expression in gastric ccarcinomas: correlation with prognostic factors and patient survival. J. Surg. Res. 139, 182-188.
    • (2007) J. Surg. Res. , vol.139 , pp. 182-188
    • Vagenas, K.1    Spyropoulos, C.2    Gavala, V.3    Tsmandas, A.C.4
  • 27
    • 67650423992 scopus 로고    scopus 로고
    • Upregulation of Eps8 in oral squamous cell carcinoma promotes cell migration and invasion through integrin-dependent Rac1 activation
    • Yap L.F., Jenei V., Robinson C.M. et al. (2009) Upregulation of Eps8 in oral squamous cell carcinoma promotes cell migration and invasion through integrin-dependent Rac1 activation. Oncogene, 28, 2524-2534.
    • (2009) Oncogene , vol.28 , pp. 2524-2534
    • Yap, L.F.1    Jenei, V.2    Robinson, C.M.3
  • 28
    • 58149213801 scopus 로고    scopus 로고
    • Non Smad pathways in TGF-β signalling
    • Zhang Y.E. (2009) Non Smad pathways in TGF-β signalling. Cell Res. 19, 128-139.
    • (2009) Cell Res. , vol.19 , pp. 128-139
    • Zhang, Y.E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.