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Volumn 74, Issue 7, 1996, Pages 1074-1080

Dysregulation of autocrine TGF-β isoform production and ligand responses in human tumour-derived and Ha-ras-transfected keratinocytes and fibroblasts

Author keywords

Fibroblast; Ha ras; Isoform; Keratinocyte; Transforming growth factor beta

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; TRANSFORMING GROWTH FACTOR BETA3;

EID: 0029784956     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/bjc.1996.492     Document Type: Article
Times cited : (26)

References (45)
  • 1
    • 0025477164 scopus 로고
    • Growth stimulation of human breast cancer cells with anti-transforming growth factor β antibodies: Evidence for negative autorine regulation by transforming growth factor
    • ARTEAGA CL, COFFEY RJ, DUGGER TC, MCCUTCHEN CM, MOSES HL AND LYONS RM. (1990). Growth stimulation of human breast cancer cells with anti-transforming growth factor β antibodies: evidence for negative autorine regulation by transforming growth factor. Cell Growth Different., 1, 367-374.
    • (1990) Cell Growth Different. , vol.1 , pp. 367-374
    • Arteaga, C.L.1    Coffey, R.J.2    Dugger, T.C.3    Mccutchen, C.M.4    Moses, H.L.5    Lyons, R.M.6
  • 2
    • 0027793115 scopus 로고
    • Evidence for a positive role of transforming growth factor-β in human breast cancer cell tumorigenesis
    • ARTEAGA CL, DUGGER TC, WINNIER AR AND FORBES JT. (1993). Evidence for a positive role of transforming growth factor-β in human breast cancer cell tumorigenesis. J. Cell. Biochem., 17G, 187-193.
    • (1993) J. Cell. Biochem. , vol.17 G , pp. 187-193
    • Arteaga, C.L.1    Dugger, T.C.2    Winnier, A.R.3    Forbes, J.T.4
  • 3
    • 0025275853 scopus 로고
    • c-Ha-ras oncogene expression in immortalised human keratinocytes (HaCaT) alters growth potential in vivo but lacks correlation with malignancy
    • BOUKAMP P., STANBRIDGE EJ, YIN FOO D, CERUTTI PA AND FUSENIG NE. (1990). c-Ha-ras oncogene expression in immortalised human keratinocytes (HaCaT) alters growth potential in vivo but lacks correlation with malignancy. Cancer Res., 50, 2840-2847.
    • (1990) Cancer Res. , vol.50 , pp. 2840-2847
    • Boukamp, P.1    Stanbridge, E.J.2    Yin Foo, D.3    Cerutti, P.A.4    Fusenig, N.E.5
  • 5
    • 0025714554 scopus 로고
    • Distinct transforming growth factor-β TGF-β receptor subsets as determinants of cellular responsiveness to three TGF-β isoforms
    • CHEIFETZ S, HERNANDEZ J, LAIHO M, TEN DIFKE P, IWATA KK AND MASSAGUE J. (1990). Distinct transforming growth factor-β (TGF-β receptor subsets as determinants of cellular responsiveness to three TGF-β isoforms. J. Biol. Chem., 265, 20533-20538.
    • (1990) J. Biol. Chem. , vol.265 , pp. 20533-20538
    • Cheifetz, S.1    Hernandez, J.2    Laiho, M.3    Ten Difke, P.4    Iwata, K.K.5    Massague, J.6
  • 7
    • 0023691647 scopus 로고
    • Selected inhibition of growth related gene expression in murine keratinocytes by transforming growth factor β
    • COFFEY RJ, BASCOM CC, SIPES NJ, GRAVES-DEAL R, WEISSMAN BE AND MOSES HL. (1988). Selected inhibition of growth related gene expression in murine keratinocytes by transforming growth factor β. Mol. Cell Biol., 8, 3088-3093.
    • (1988) Mol. Cell Biol. , vol.8 , pp. 3088-3093
    • Coffey, R.J.1    Bascom, C.C.2    Sipes, N.J.3    Graves-Deal, R.4    Weissman, B.E.5    Moses, H.L.6
  • 9
    • 0027399259 scopus 로고
    • Reduced expression of TGF-β is associated with advanced disease in transitional cell carcinoma
    • COOMBS LM, PIGOTT DA, EYDMANN ME, PROCTOR AJ AND KNOWLES MA. (1993). Reduced expression of TGF-β is associated with advanced disease in transitional cell carcinoma. Br. J. Cancer, 67, 578-584.
    • (1993) Br. J. Cancer , vol.67 , pp. 578-584
    • Coombs, L.M.1    Pigott, D.A.2    Eydmann, M.E.3    Proctor, A.J.4    Knowles, M.A.5
  • 11
    • 0027505882 scopus 로고
    • Improved sandwich enzyme-linked immunosorbent assays for transforming growth factor β1
    • DANIELPOUR D. (1993). Improved sandwich enzyme-linked immunosorbent assays for transforming growth factor β1. J. Immunol. Methods, 158, 17-25.
    • (1993) J. Immunol. Methods , vol.158 , pp. 17-25
    • Danielpour, D.1
  • 12
    • 0025886485 scopus 로고
    • Differential regulation of the regulation of transforming growth factor-βs 1 and 2 by retinoic acid, epidermal growth factor and dexamethasone in NRK-49F and A549 cells
    • DANIELPOUR D, KIM KY, WINOKUR TS AND SPORN MB. (1991). Differential regulation of the regulation of transforming growth factor-βs 1 and 2 by retinoic acid, epidermal growth factor and dexamethasone in NRK-49F and A549 cells. J. Cell. Physiol., 148, 235-244.
    • (1991) J. Cell. Physiol. , vol.148 , pp. 235-244
    • Danielpour, D.1    Kim, K.Y.2    Winokur, T.S.3    Sporn, M.B.4
  • 13
    • 0023100052 scopus 로고
    • Synthesis of messenger RNAs for transforming growth factor α and β and the epidermal growth factor receptor by human tumours
    • DERYNCK R, GOEDDEL DV, ULLRICH A, GUTTERMAN JY, WILLIAMS RD AND BRINGMAN TS. (1987). Synthesis of messenger RNAs for transforming growth factor α and β and the epidermal growth factor receptor by human tumours. Cancer Res., 47, 707-712.
    • (1987) Cancer Res. , vol.47 , pp. 707-712
    • Derynck, R.1    Goeddel, D.V.2    Ullrich, A.3    Gutterman, J.Y.4    Williams, R.D.5    Bringman, T.S.6
  • 14
    • 0009745229 scopus 로고
    • Malignant transformation of mouse primary keratinocytes by Harvey sarcoma virus and its modulation by surrounding normal cells
    • DOTTO GP, WEINBERG RA AND ARIZA A. (1988). Malignant transformation of mouse primary keratinocytes by Harvey sarcoma virus and its modulation by surrounding normal cells. Proc. Natl Acad. Sci. USA, 85, 6389-6393.
    • (1988) Proc. Natl Acad. Sci. USA , vol.85 , pp. 6389-6393
    • Dotto, G.P.1    Weinberg, R.A.2    Ariza, A.3
  • 15
    • 0028978505 scopus 로고
    • Cellular immortality-a late event in the progression of human squamous cell carcinoma of the head and neck associated with p53 alteration and a high frequency of allele loss
    • EDINGTON KG, LOUGHRAM OP, BERRY IJ AND PARKINSON EK. (1995). Cellular immortality-a late event in the progression of human squamous cell carcinoma of the head and neck associated with p53 alteration and a high frequency of allele loss. Mol. Carcinogen., 13, 254-265.
    • (1995) Mol. Carcinogen. , vol.13 , pp. 254-265
    • Edington, K.G.1    Loughram, O.P.2    Berry, I.J.3    Parkinson, E.K.4
  • 16
    • 0027421280 scopus 로고
    • Resistance to inhibition of cell growth by transforming growth factor-β and its role in oncogenesis
    • FYNAN TM AND REISS M. (1993). Resistance to inhibition of cell growth by transforming growth factor-β and its role in oncogenesis. Crit. Rev. Oncogen., 4, 493-540.
    • (1993) Crit. Rev. Oncogen. , vol.4 , pp. 493-540
    • Fynan, T.M.1    Reiss, M.2
  • 17
    • 0026662423 scopus 로고
    • Progressive abrogation of TGF-β1 and EGF growth control is associated with tumour progression in ras-transfected human keratinocytes
    • GAME SM, HUELSON A, PATEL V, DONNELLY M, YEUDALL WA, STONE A, FUSENIG NE AND PRIME SS. (1992). Progressive abrogation of TGF-β1 and EGF growth control is associated with tumour progression in ras-transfected human keratinocytes. Int. J. Cancer, 52, 461-470.
    • (1992) Int. J. Cancer , vol.52 , pp. 461-470
    • Game, S.M.1    Huelson, A.2    Patel, V.3    Donnelly, M.4    Yeudall, W.A.5    Stone, A.6    Fusenig, N.E.7    Prime, S.S.8
  • 18
    • 0026068693 scopus 로고
    • Characterisation of the mouse transforming growth factor-β1 promoter and activation by the Ha-ras oncogene
    • GEISER AG, KIM SJ, ROBERTS AB AND SPORN MB. (1991). Characterisation of the mouse transforming growth factor-β1 promoter and activation by the Ha-ras oncogene. Mol. Cell. Biol., 11, 84-92.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 84-92
    • Geiser, A.G.1    Kim, S.J.2    Roberts, A.B.3    Sporn, M.B.4
  • 20
    • 0028171401 scopus 로고
    • Targeted deletion of the TGF-β1 gene causes rapid progression to squamous cell carcinoma
    • GLICK AB, LEE MM, DARWICHE N, KULKARNI AB, KARLSSON S AND YUSPA SH. (1994). Targeted deletion of the TGF-β1 gene causes rapid progression to squamous cell carcinoma. Genes Dev., 8, 2429-2440.
    • (1994) Genes Dev. , vol.8 , pp. 2429-2440
    • Glick, A.B.1    Lee, M.M.2    Darwiche, N.3    Kulkarni, A.B.4    Karlsson, S.5    Yuspa, S.H.6
  • 21
    • 0027053058 scopus 로고
    • Immunohistochemical staining for transforming growth factor-β1 associates with disease progression in human breast cancer
    • GORSCH SM, MEMOLI VA, STUKEL TA, GOLD LI AND ARRICK BA. (1992). Immunohistochemical staining for transforming growth factor-β1 associates with disease progression in human breast cancer. Cancer Res., 52, 6949-6952.
    • (1992) Cancer Res. , vol.52 , pp. 6949-6952
    • Gorsch, S.M.1    Memoli, V.A.2    Stukel, T.A.3    Gold, L.I.4    Arrick, B.A.5
  • 22
    • 0025654204 scopus 로고
    • Transforming growth factor beta 1 acts as an autocrine-negative growth regulator in colon enterocytic differentiation but not in goblet cell maturation
    • HAFEZ MM, INFANTE D, WINAWER S AND FRIEDMAN E. (1990). Transforming growth factor beta 1 acts as an autocrine-negative growth regulator in colon enterocytic differentiation but not in goblet cell maturation. Cell Growth Different., 1, 617-626.
    • (1990) Cell Growth Different. , vol.1 , pp. 617-626
    • Hafez, M.M.1    Infante, D.2    Winawer, S.3    Friedman, E.4
  • 25
    • 0029314729 scopus 로고
    • Transforming growth factor-β: An overview
    • LAWRENCE DA. (1995). Transforming growth factor-β: an overview. Kidney Int., 47, S19-S23.
    • (1995) Kidney Int. , vol.47
    • Lawrence, D.A.1
  • 27
    • 0027743449 scopus 로고
    • Spatial and temporal patterns of immunoreactive TGF-β1, TGF-β2 and TGF-β3 during excisional wound repair
    • LEVINE JH, MOSES HL, GOLD LI AND NANNEY LB. (1993). Spatial and temporal patterns of immunoreactive TGF-β1, TGF-β2 and TGF-β3 during excisional wound repair. Am. J. Pathol., 143, 368-380.
    • (1993) Am. J. Pathol. , vol.143 , pp. 368-380
    • Levine, J.H.1    Moses, H.L.2    Gold, L.I.3    Nanney, L.B.4
  • 29
    • 0026004630 scopus 로고
    • Escape from transforming growth factor β control and oncogene cooperation in skin tumor development
    • MISSERO C, CAJAL SR AND DOTTO GP. (1991). Escape from transforming growth factor β control and oncogene cooperation in skin tumor development. Proc. Natl Acad. Sci. USA, 88, 9613-9617.
    • (1991) Proc. Natl Acad. Sci. USA , vol.88 , pp. 9613-9617
    • Missero, C.1    Cajal, S.R.2    Dotto, G.P.3
  • 30
    • 0026863599 scopus 로고
    • Transforming growth factor β1 regulation of c-myc expression, pRB phosphorylation and cell cycle progression in keratinocytes
    • MUNGER K, PIETENPOL JA, PITTELKOW MR, HOLT JT AND MOSES HL. (1992). Transforming growth factor β1 regulation of c-myc expression, pRB phosphorylation and cell cycle progression in keratinocytes. Cell Growth Different., 3, 291-298.
    • (1992) Cell Growth Different. , vol.3 , pp. 291-298
    • Munger, K.1    Pietenpol, J.A.2    Pittelkow, M.R.3    Holt, J.T.4    Moses, H.L.5
  • 32
    • 0026326375 scopus 로고
    • Immunohistochemical localization of TGF-β1, TGF-β2 and TGF-β3 in the mouse embryo: Expression patterns suggest multiple roles during embryonic development
    • PELTON RW, SAXENA B, JONES M, MOSES HL AND GOLD LI. (1991). Immunohistochemical localization of TGF-β1, TGF-β2 and TGF-β3 in the mouse embryo: expression patterns suggest multiple roles during embryonic development. J. Cell Biol., 115, 1091-1105.
    • (1991) J. Cell Biol. , vol.115 , pp. 1091-1105
    • Pelton, R.W.1    Saxena, B.2    Jones, M.3    Moses, H.L.4    Gold, L.I.5
  • 33
    • 0025329363 scopus 로고
    • Transforming growth factor-β suppression of c-myc gene transcription: Role in inhibition of keratinocyte proliferation
    • PIETENPOL JA, HOLT JT, STEIN RW AND MOSES HL. (1990). Transforming growth factor-β suppression of c-myc gene transcription: role in inhibition of keratinocyte proliferation. Proc. Natl Acad. Sci. USA, 87, 3758-3762.
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , pp. 3758-3762
    • Pietenpol, J.A.1    Holt, J.T.2    Stein, R.W.3    Moses, H.L.4
  • 35
    • 0028179164 scopus 로고
    • TGF-β receptor regulation mediates the response to exogenous ligand but is independent of the degree of cellular differentiation in human oral keratinocytes
    • PRIME SS, MATTHEWS JB, PATEL V, GAME SM, DONNELLY M, STONE A, PATERSON IC, SANDY JR AND YEUDALL WA. (1994). TGF-β receptor regulation mediates the response to exogenous ligand but is independent of the degree of cellular differentiation in human oral keratinocytes. Int. J. Cancer, 56, 406-412.
    • (1994) Int. J. Cancer , vol.56 , pp. 406-412
    • Prime, S.S.1    Matthews, J.B.2    Patel, V.3    Game, S.M.4    Donnelly, M.5    Stone, A.6    Paterson, I.C.7    Sandy, J.R.8    Yeudall, W.A.9
  • 36
    • 0000116653 scopus 로고
    • The transforming growth factors
    • Sporn MB and Roberts AB (eds) Springer: Berlin
    • ROBERTS AB AND SPORN MB. (1991). The transforming growth factors. In Peptide Growth Factors and their Receptors I. Sporn MB and Roberts AB (eds) pp. 419-472. Springer: Berlin.
    • (1991) Peptide Growth Factors and Their Receptors I , pp. 419-472
    • Roberts, A.B.1    Sporn, M.B.2
  • 37
    • 0028003705 scopus 로고
    • Phenotypic heterogeneity in breast fibroblasts: Functional anomaly in fibroblasts from histologically normal tissue adjacent to carcinoma
    • SCHOR AM, RUSHTON G, FERGUSON JE, HOWELL A. REDFORD J AND SCHOR SL. (1994). Phenotypic heterogeneity in breast fibroblasts: functional anomaly in fibroblasts from histologically normal tissue adjacent to carcinoma. Int. J. Cancer, 59, 25-32.
    • (1994) Int. J. Cancer , vol.59 , pp. 25-32
    • Schor, A.M.1    Rushton, G.2    Ferguson, J.E.3    Howell, A.4    Redford, J.5    Schor, S.L.6
  • 38
    • 0028986030 scopus 로고
    • Neutralization of TGF-β1 and TGF-β2 or exogenous addition of the TGF-β3 to cutaneous rat wounds reduces scarring
    • SHAH M, FOREMAN DM AND FERGUSON MWJ. (1995). Neutralization of TGF-β1 and TGF-β2 or exogenous addition of the TGF-β3 to cutaneous rat wounds reduces scarring. J. Cell Sci., 108, 985-1002.
    • (1995) J. Cell Sci. , vol.108 , pp. 985-1002
    • Shah, M.1    Foreman, D.M.2    Ferguson, M.W.J.3
  • 39
    • 0026445528 scopus 로고
    • Transforming growth factor-B: Recent progress and new challenges
    • SPORN MB AND ROBERTS AB. (1992). Transforming growth factor-B: recent progress and new challenges. J. Cell. Biol., 119, 1017-1021.
    • (1992) J. Cell. Biol. , vol.119 , pp. 1017-1021
    • Sporn, M.B.1    Roberts, A.B.2
  • 40
    • 0026699253 scopus 로고
    • Particular types of tumour cells have the capacity to convert transforming growth factor β from a latent to an active form
    • TAKIUCHI H, TADA T, LI X-F, OGATA M, IKEDA T, EUJIMOTO S, FUJIWARA H AND HAMAOKA T. (1992). Particular types of tumour cells have the capacity to convert transforming growth factor β from a latent to an active form. Cancer Res., 52, 5641-5646.
    • (1992) Cancer Res. , vol.52 , pp. 5641-5646
    • Takiuchi, H.1    Tada, T.2    Li, X.-F.3    Ogata, M.4    Ikeda, T.5    Eujimoto, S.6    Fujiwara, H.7    Hamaoka, T.8
  • 42
    • 11944255353 scopus 로고
    • Transforming growth factor β stimulates mammary adenocarcinoma cell invasion and metastatic potential
    • WELCH DR, FABRA A AND NAKAJIMA M. (1990). Transforming growth factor β stimulates mammary adenocarcinoma cell invasion and metastatic potential. Proc. Natl Acad. Sci. USA, 87, 7678-7682.
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , pp. 7678-7682
    • Welch, D.R.1    Fabra, A.2    Nakajima, M.3
  • 43
    • 0026513154 scopus 로고
    • TGF-β1 is an autocrine-negativc growth regulator of human colon carcinoma FET cells in vivo as revealed by transfection of an anti-sense expression vector
    • WU S, THEODORESCU D, KERBEL RS, WILLSON JKV, MULDER KV, HUMPHREY LE AND BRATTAIN MG. (1992). TGF-β1 is an autocrine-negativc growth regulator of human colon carcinoma FET cells in vivo as revealed by transfection of an anti-sense expression vector. J. Cell Biol., 116, 187-196.
    • (1992) J. Cell Biol. , vol.116 , pp. 187-196
    • Wu, S.1    Theodorescu, D.2    Kerbel, R.S.3    Willson, J.K.V.4    Mulder, K.V.5    Humphrey, L.E.6    Brattain, M.G.7
  • 44
    • 0027474504 scopus 로고
    • Ras gene point mutation is a rare event in premalignant and malignant lesions of the oral cavity
    • YEUDALL WA, TORRANCE LK, ELSEGOOD KA, SPEIGHT PA AND PRIME SS. (1993). Ras gene point mutation is a rare event in premalignant and malignant lesions of the oral cavity. Eur, J. Cancer, 29B, 63-68.
    • (1993) Eur, J. Cancer , vol.29 B , pp. 63-68
    • Yeudall, W.A.1    Torrance, L.K.2    Elsegood, K.A.3    Speight, P.A.4    Prime, S.S.5
  • 45
    • 0029079133 scopus 로고
    • Presence of human papillomavirus sequences in tumour-derived human oral keratinocytes which express mutant p53
    • YEUDALL WA, PATERSON IC, PATEL V AND PRIME SS. (1995). Presence of human papillomavirus sequences in tumour-derived human oral keratinocytes which express mutant p53. Eur. J. Cancer, 31B, 136-143.
    • (1995) Eur. J. Cancer , vol.31 B , pp. 136-143
    • Yeudall, W.A.1    Paterson, I.C.2    Patel, V.3    Prime, S.S.4


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