Effect of alveolar epithelial cell plasticity on the regulation of GM-CSF expression

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 302, Issue 6, 2012, Pages

  Mir Kasimov, Mustafa ^a   Sturrock, Anne ^a   McManus, Michael ^a   Paine III, Robert ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

Alveolar macrophages; Cell cell interaction; Granulocyte macrophage colony stimulating factor; Growth factors; Innate immunity; Lung

Indexed keywords

COLLAGEN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HYALURONIC ACID; INTERLEUKIN 1BETA; SURFACTANT PROTEIN C; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL INTERACTION; INNATE IMMUNITY; LUNG ALVEOLUS EPITHELIUM; LUNG INJURY; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CELL LINE; COLLAGEN; CULTURE MEDIA; EPITHELIAL CELLS; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HOMEOSTASIS; HYALURONIC ACID; INTERLEUKIN-1BETA; LUNG INJURY; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; PEPTIDES; PULMONARY ALVEOLI; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84858196480     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00303.2010     Document Type: Article

References (35)

1. Baleeiro CE, Christensen PJ, Morris SB, Mendez MP, Wilcoxen SE, Paine R III. GM-CSF and the impaired pulmonary innate immune response following hyperoxic stress. Am J Physiol Lung Cell Mol Physiol 291: L1246-L1255, 2006.
2. Baleeiro CE, Wilcoxen SE, Morris SB, Standiford TJ, Paine R III. Sublethal hyperoxia impairs pulmonary innate immunity. J Immunol 171: 955-963, 2003.
3. Beck JM, Preston AM, Wilcoxen SE, Morris SB, Sturrock A, Paine R III. Critical roles of inflammation and apoptosis in improved survival in a model of hyperoxia-induced acute lung injury in Pneumocystis murinainfected mice. Infect Immun 77: 1053-1060, 2009.
4. Bozinovski S, Jones J, Beavitt SJ, Cook AD, Hamilton JA, Anderson GP. Innate immune responses to LPS in mouse lung are suppressed and reversed by neutralization of GM-CSF via repression of TLR-4. Am J Physiol Lung Cell Mol Physiol 286: L877-L885, 2004.
5. Cakarova L, Marsh LM, Wilhelm J, Mayer K, Grimminger F, Seeger W, Lohmeyer J, Herold S. Macrophage tumor necrosis factor-alpha induces epithelial expression of granulocyte-macrophage colony-stimulating factor: impact on alveolar epithelial repair. Am J Respir Crit Care Med 180: 521-532, 2009.
6. Campbell IK, Bendele A, Smith DA, Hamilton JA. Granulocytemacrophage colony stimulating factor exacerbates collagen induced arthritis in mice. Ann Rheum Dis 56: 364-368, 1997.
7. Christensen PJ, Bailie MB, Goodman RE, O'Brien AD, Toews GB, Paine R III. Role of diminished epithelial GM-CSF in the pathogenesis of bleomycin-induced pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol 279: L487-L495, 2000.
8. Corti M, Brody AR, Harrison JH. Isolation and primary culture of murine alveolar type II cells. Am J Respir Cell Mol Biol 14: 309-315, 1996.
9. Demaio L, Tseng W, Balverde Z, Alvarez JR, Kim KJ, Kelley DG, Senior RM, Crandall ED, Borok Z. Characterization of mouse alveolar epithelial cell monolayers. Am J Physiol Lung Cell Mol Physiol 296: L1051-L1058, 2009.
10. Dranoff G, Crawford AD, Sadelain M, Ream B, Rashid A, Bronson RT, Dickersin GR, Bachurski CJ, Mark EL, Whitsett JA, Mulligan RC. Involvement of granulocyte-macrophage colony-stimulating factor in pulmonary homeostasis. Science 264: 713-716, 1994.
11. Huffman JA, Hull WM, Dranoff G, Mulligan RC, Whitsett JA. Pulmonary epithelial cell expression of GM-CSF corrects the alveolar proteinosis in GM-CSF-deficient mice. J Clin Invest 97: 649-655, 1996.
12. Kim KK, Kugler MC, Wolters PJ, Robillard L, Galvez MG, Brumwell AN, Sheppard D, Chapman HA. Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix. Proc Natl Acad Sci USA 103: 13180-13185, 2006.
13. Koval M, Ward C, Findley MK, Roser-Page S, Helms MN, Roman J. Extracellular matrix influences alveolar epithelial claudin expression and barrier function. Am J Respir Cell Mol Biol 42: 172-180, 2010.
14. LeVine AM, Reed JA, Kurak KE, Cianciolo E, Whitsett JA. GM-CSFdeficient mice are susceptible to pulmonary group B streptococcal infection. J Clin Invest 103: 563-569, 1999.
15. Metcalf D, Nicola NA, Mifsud S, Di Rago L. Receptor clearance obscures the magnitude of granulocyte-macrophage colony-stimulating factor responses in mice to endotoxin or local infections. Blood 93: 1579-1585, 1999.
16. Nishinakamura R, Wiler R, Dirksen U, Morikawa Y, Arai K, Miyajima A, Burdach S, Murray R. The pulmonary alveolar proteinosis in granulocyte macrophage colony-stimulating factor/interleukins 3/5 beta c receptor-deficient mice is reversed by bone marrow transplantation. J Exp Med 183: 2657-2662, 1996.
17. Paine R III, Christensen P, Toews GB, Simon RH. Regulation of alveolar epithelial cell ICAM-1 expression by cell shape and cell-cell interactions. Am J Physiol Lung Cell Mol Physiol 266: L476-L484, 1994.
18. Paine R III, Morris SB, Jin H, Wilcoxen SE, Phare SM, Moore BB, Coffey MJ, Toews GB. Impaired functional activity of alveolar macrophages from GM-CSF-deficient mice. Am J Physiol Lung Cell Mol Physiol 281: L1210-L1218, 2001.
19. Paine R III, Preston AM, Wilcoxen S, Jin H, Siu BB, Morris SB, Reed JA, Ross G, Whitsett JA, Beck JM. Granulocyte-macrophage colonystimulating factor in the innate immune response to Pneumocystis carinii pneumonia in mice. J Immunol 164: 2602-2609, 2000.
20. Paine R, III, Wilcoxen SE, Morris SB, Sartori C, Baleeiro CEO, Matthay MA, Christensen PJ. Transgenic overexpression of granulocyte macrophage-colony stimulating factor in the lung prevents hyperoxic lung injury. Am J Pathol 163: 2397-2406, 2003.
21. Reed JA, Ikegami M, Cianciolo ER, Lu W, Cho PS, Hull W, Jobe AH, Whitsett JA. Aerosolized GM-CSF ameliorates pulmonary alveolar proteinosis in GM-CSF-deficient mice. Am J Physiol Lung Cell Mol Physiol 276: L556-L563, 1999.
22. Reed JA, Whitsett JA. Granulocyte-macrophage colony-stimulating factor and pulmonary surfactant homeostasis. Proc Assoc Am Physicians 110: 321-332, 1998.
23. Reynolds PR, Schmitt RE, Kasteler SD, Sturrock A, Sanders K, Bierhaus A, Nawroth PP, Paine R III, Hoidal JR. Receptors for advanced glycation end-products targeting protect against hyperoxiainduced lung injury in mice. Am J Respir Cell Mol Biol 42: 545-551, 2010.
24. Robb L, Drinkwater CC, Metcalf D, Li R, Kontgen F, Nicola NA, Begley CG. Hematopoietic and lung abnormalities in mice with a null mutation of the common beta subunit of the receptors for granulocytemacrophage colony-stimulating factor and interleukins 3 and 5. Proc Natl Acad Sci USA 92: 9565-9569, 1995.
25. Shannon JM, Jennings SD, Nielsen LD. Modulation of alveolar type II cell differentiated function in vitro. Am J Physiol Lung Cell Mol Physiol 262: L427-L436, 1992.
26. Shannon JM, Mason RJ, Jennings SD. Functional differentiation of alveolar type II epithelial cells in vitro: effects of cell shape, cell-matrix interactions and cell-cell interactions. Biochim Biophys Acta 931: 143-156, 1987.
27. Shibata Y, Berclaz PY, Chroneos ZC, Yoshida M, Whitsett JA, Trapnell BC. GM-CSF regulates alveolar macrophage differentiation and innate immunity in the lung through PU1. Immunity 15: 557-567, 2001.
28. Stanley E, Lieschke GJ, Grail D, Metcalf D, Hodgson G, Gall JA, Maher DW, Cebon J, Sinickas V, Dunn AR. Granulocyte/macrophage colony-stimulating factor-deficient mice show no major perturbation of hematopoiesis but develop a characteristic pulmonary pathology. Proc Natl Acad Sci USA 91: 5592-5596, 1994.
29. Sturrock A, Vollbrecht T, Mir-Kasimov M, McManus M, Wilcoxen SE, Paine R III. Mechanisms of suppression of alveolar epithelial cell GM-CSF expression in the setting of hyperoxic stress. Am J Physiol Lung Cell Mol Physiol 298: L446-L453, 2010.
30. Trapnell BC, Whitsett JA, Nakata K. Pulmonary alveolar proteinosis. N Engl J Med 349: 2527-2539, 2003.
31. Warburton D, Schwarz M, Tefft D, Flores-Delgado G, Anderson KD, Cardoso WV. The molecular basis of lung morphogenesis. Mech Dev 92: 55-81, 2000.
32. Wikenheiser KA, Vorbroker DK, Rice WR, Clark JC, Bachurski CJ, Oie HK, Whitsett JA. Production of immortalized distal respiratory epithelial cell lines from surfactant protein C/simian virus 40 large tumor antigen transgenic mice. Proc Natl Acad Sci USA 90: 11029-11033, 1993.
33. Wunderlich S, Gruh I, Winkler ME, Beier J, Radtke K, Schmiedl A, Groos S, Haverich A, Martin U. Type II pneumocyte-restricted green fluorescent protein expression after lentiviral transduction of lung epithelial cells. Hum Gene Ther 19: 39-52, 2008.
34. Xing Z, Tremblay GM, Sime PJ, Gauldie J. Overexpression of granulocyte- macrophage colony-stimulating factor induces pulmonary granulation tissue formation and fibrosis by induction of transforming growth factor-beta 1 and myofibroblast accumulation. Am J Pathol 150: 59-66, 1997.
35. Yu W, Fang X, Ewald A, Wong K, Hunt CA, Werb Z, Matthay MA, Mostov K. Formation of cysts by alveolar type II cells in three-dimensional culture reveals a novel mechanism for epithelial morphogenesis. Mol Biol Cell 18: 1693-1700, 2007.