Impaired functional activity of alveolar macrophages from GM-CSF-deficient mice

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 281, Issue 5 25-5, 2001, Pages

  Paine III, Robert ^a,b   Morris, Susan B ^a   Jin, Hong ^a   Wilcoxen, Steven E ^a   Phare, Susan M ^a   Moore, Bethany B ^a   Coffey, Michael J ^a   Toews, Galen B ^a,b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b VA ANN ARBOR HEALTHCARE SYSTEM   (United States)

Author keywords

Granulocyte macrophage colony stimulating factor; Growth factors; Inflammation; Lung; Transgenic knockout

Indexed keywords

GLYCOPROTEIN P 15095; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTEGRIN; LEUKOTRIENE; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; CYTOKINE RELEASE; HOST RESISTANCE; LUNG ALVEOLUS MACROPHAGE; LUNG FUNCTION; LUNG LAVAGE; MOUSE; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL;

EID: 0035195353     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.2001.281.5.l1210     Document Type: Article

References (33)

1. Effects of granulocyte-macrophage colony-stimulating factor and colony stimulating factor-1 on the proliferation and differentiation of murine alveolar macrophages
2. Inflammatory responses to Pneumocystis carinii in mice selectively depleted of helper T lymphocytes
3. Pulmonary macrophages
4. Surfactant-associated protein A inhibits LPS-induced cytokine and nitric oxide production in vivo
5. Alveolar macrophages are required for protective pulmonary defenses in murine Klebsiella pneumonia: Elimination of alveolar macrophages increases neutrophil recruitment but decreases bacterial clearance and survival
6. Purification and properties of colony-stimulating factor from mouse lung-conditioned medium
7. Effect of granulocyte-macrophage colony-stimulating factor on rat alveolar macrophage anticryptococcal activity in vitro
8. Involvement of granulocyte-macrophage colony-stimulating factor in pulmonary homeostasis
9. The alveolar macrophage
10. Molecular physiology of granulocyte-macrophage colony-stimulating factor
11. Alveolar macrophages
12. Pulmonary epithelial cell expression of GM-CSF corrects the alveolar proteinosis in GM-CSF-deficient mice
13. GM-CSF-deficient mice are susceptible to pulmonary group B streptococcal infection
14. The role of alveolar macrophages in Pneumocystis carinii degradation and clearance from the lung
15. The role of alveolar macrophages in Pneumocystis carinii elimination from the lower respiratory tract
16. Surfactant protein A protects growing cells and reduces TNF-α activity from LPS-stimulated macrophages
17. Granulocyte-macrophage colony-stimulating factor promotes the proliferation of human alveolar macrophages in vitro
18. Secretory products of macrophages
19. Mice deficient for the IL-3/GM-CSF/IL-5 beta c receptor exhibit lung pathology and impaired immune response, while beta IL3 receptor-deficient mice are normal
20. Chemotaxis of alveolar macrophages in response to signals derived from alveolar epithelial cells
21. Granulocyte-macrophage colony-stimulating factor in the innate immune response to Pneumocystis carinii pneumonia in mice
22. Aerosolized GM-CSF ameliorates pulmonary alveolar proteinosis in GM-CSF-deficient mice
23. Granulocyte-macrophage colony-stimulating factor and pulmonary surfactant homeostasis
24. Recombinant granulocyte/macrophage colony-stimulating factor activates macrophages to inhibit Trypanosoma cruzi and release hydrogen peroxide. Comparison with interferon gamma
25. Hematopoietic and lung abnormalities in mice with a null mutation of the common beta subunit of the receptors for granulocyte-macrophage colony-stimulating factor and interleukins 3 and 5
26. Human recombinant granulocyte-macrophage colony-stimulating factor augments viability and cytotoxic activities of human monocyte-derived macrophages in long-term cultures
27. The common chain (beta c) of the granulocyte macrophage-colony stimulating factor, interleukin-3 and interleukin-5 receptors
28. Functional analysis of mature hematopoietic cells from mice lacking the beta c chain of the granulocyte-macrophage colony-stimulating factor receptor
29. Mac-1 (CD11b/CD18) mediates adherence-dependent hydrogen peroxide production by human and canine neutrophils
30. Binding of Griffonia simplicifolia I lectin to rat pulmonary alveolar macrophages and its use in purifying type II alveolar epithelial cells
31. Chemokines
32. Selective expansion of alveolar macrophages in vivo by adenovirus-mediated transfer of the murine granulocyte-macrophage colony-stimulating factor cDNA
33. Adenovirus-mediated granulocyte-macrophage colony-stimulating factor improves lung pathology of pulmonary alveolar proteinosis in granulocyte-macrophage colony-stimulating factor-deficient mice