Characterization of mouse alveolar epithelial cell monolayers

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 296, Issue 6, 2009, Pages

  DeMaio, Lucas ^a   Tseng, Wanru ^a   Balverde, Zerlinde ^a   Alvarez, Juan R ^a   Kim, Kwang Jin ^a   Kelley, Diane G ^c   Senior, Robert M ^c   Crandall, Edward D ^a   Borok, Zea ^a,b  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c WASHINGTON UNIVERSITY   (United States)

Author keywords

Alveolar epithelium; Ion transport; Phenotypic transition; Short circuit current; Transepithelial resistance

Indexed keywords

AMILORIDE; AQUAPORIN 5; CHLORIDE; KALININ; OUABAIN; PIMOZIDE; PROTEIN C; SODIUM; TERBUTALINE;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CHLORIDE TRANSPORT; CONTROLLED STUDY; EXTRACELLULAR MATRIX; LUNG ALVEOLUS EPITHELIUM; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SHORT CIRCUIT CURRENT; SODIUM TRANSPORT;

AMILORIDE; ANIMALS; BIOLOGICAL TRANSPORT, ACTIVE; BRONCHODILATOR AGENTS; CELL CULTURE TECHNIQUES; CELLS, CULTURED; CHLORIDES; DIFFUSION CHAMBERS, CULTURE; DOPAMINE ANTAGONISTS; ELECTRIC IMPEDANCE; ENZYME INHIBITORS; EPITHELIAL CELLS; MICE; MICE, INBRED STRAINS; OUABAIN; PHENOTYPE; PIMOZIDE; PULMONARY ALVEOLI; RESPIRATORY MUCOSA; SODIUM; SODIUM CHANNEL BLOCKERS; TERBUTALINE;

EID: 67049172467     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00021.2009     Document Type: Article

References (49)

1. Berthiaume Y, Broaddus VC, Gropper MA, Tanita T, Matthay MA. Alveolar liquid and protein clearance from normal dog lungs. J Appl Physiol 65: 585-593, 1988. (Pubitemid 18210167)
2. +- ATPase expression in alveolar epithelial cells: upregulation of active ion transport by KGF. Am J Physiol Lung Cell Mol Physiol 274: L149-L158, 1998.
3. Borok Z, Danto SI, Lubman RL, Cao Y, Williams MC, Crandall ED. Modulation of T1α expression with alveolar epithelial cell phenotype in vitro. Am J Physiol Lung Cell Mol Physiol 275: L155-L164, 1998.
4. Borok Z, Hami A, Danto SI, Lubman RL, Kim KJ, Crandall ED. Effects of EGF on alveolar epithelial junctional permeability and active sodium transport. Am J Physiol Lung Cell Mol Physiol 270: L559-L565, 1996.
5. Borok Z, Hami A, Danto SI, Zabski SM, Crandall ED. Rat serum inhibits progression of alveolar epithelial cells toward the type I cell phenotype in vitro. Am J Respir Cell Mol Biol 12: 50-55, 1995.
6. Borok Z, Liebler JM, Lubman RL, Foster MJ, Zhou B, Li X, Zabski SM, Kim KJ, Crandall ED. Na transport proteins are expressed by rat alveolar epithelial type I cells. Am J Physiol Lung Cell Mol Physiol 282: L599-L608, 2002.
7. Borok Z, Lubman RL, Danto SI, Zhang XL, Zabski SM, King LS, Lee DM, Agre P, Crandall ED. Keratinocyte growth factor modulates alveolar epithelial cell phenotype in vitro: expression of aquaporin 5. Am J Respir Cell Mol Biol 18: 554-561, 1998.
8. Borok Z, Mihyu S, Fernandes VF, Zhang XL, Kim KJ, Lubman RL. KGF prevents hyperoxia-induced reduction of active ion transport in alveolar epithelial cells. Am J Physiol Cell Physiol 276: C1352-C1360, 1999. (Pubitemid 29323400)
9. Cheek JM, Kim KJ, Crandall ED. Tight monolayers of rat alveolar epithelial cells: bioelectric properties and active sodium transport. Am J Physiol Cell Physiol 256: C688-C693, 1989.
10. Chen SP, Zhou B, Willis BC, Sandoval AJ, Liebler JM, Kim KJ, Ann DK, Crandall ED, Borok Z. Effects of transdifferentiation and EGF on claudin isoform expression in alveolar epithelial cells. J Appl Physiol 98: 322-328, 2005. (Pubitemid 40041263)
11. Corti M, Brody AR, Harrison JH. Isolation and primary culture of murine alveolar type II cells. Am J Respir Cell Mol Biol 14: 309-315, 1996. (Pubitemid 126440495)
12. Crandall ED, Matthay MA. Alveolar epithelial transport. Basic science to clinical medicine. Am J Respir Crit Care Med 163: 1021-1029, 2001. (Pubitemid 32275880)
13. Danto SI, Borok Z, Zhang XL, Lopez MZ, Patel P, Crandall ED, Lubman RL. Mechanisms of EGF-induced stimulation of sodium reabsorption by alveolar epithelial cells. Am J Physiol Cell Physiol 275: C82-C92, 1998. (Pubitemid 28381306)
14. Danto SI, Shannon JM, Borok Z, Zabski SM, Crandall ED. Reversible transdifferentiation of alveolar epithelial cells. Am J Respir Cell Mol Biol 12: 497-502, 1995.
15. Danto SI, Zabski SM, Crandall ED. Reactivity of alveolar epithelial cells in primary culture with type I cell monoclonal antibodies. Am J Respir Cell Mol Biol 6: 296-306, 1992.
16. Dobbs LG, Williams MC, Gonzalez R. Monoclonal antibodies specific to apical surfaces of rat alveolar type I cells bind to surfaces of cultured, but not freshly isolated, type II cells. Biochim Biophys Acta 970: 146-156, 1988. (Pubitemid 18154411)
17. Dunsmore SE, Rannels DE. Extracellular matrix biology in the lung. Am J Physiol Lung Cell Mol Physiol 270: L3-L27, 1996. (Pubitemid 26057327)
18. Egli M, Duplain H, Lepori M, Cook S, Nicod P, Hummler E, Sartori C, Scherrer U. Defective respiratory amiloride-sensitive sodium transport predisposes to pulmonary oedema and delays its resolution in mice. J Physiol 560: 857-865, 2004. (Pubitemid 39530123)
19. Elbert KJ, Schafer UF, Schafers HJ, Kim KJ, Lee VH, Lehr CM. Monolayers of human alveolar epithelial cells in primary culture for pulmonary absorption and transport studies. Pharm Res 16: 601-608, 1999. (Pubitemid 29227086)
20. Fang X, Fukuda N, Barbry P, Sartori C, Verkman AS, Matthay MA. Novel role for CFTR in fluid absorption from the distal airspaces of the lung. J Gen Physiol 119: 199-207, 2002. (Pubitemid 34522236)
21. Fang X, Song Y, Hirsch J, Galietta LJ, Pedemonte N, Zemans RL, Dolganov G, Verkman AS, Matthay MA. Contribution of CFTR to apical-basolateral fluid transport in cultured human alveolar epithelial type II cells. Am J Physiol Lung Cell Mol Physiol 290: L242-L249, 2006.
22. Goodman BE, Crandall ED. Dome formation in primary cultured monolayers of alveolar epithelial cells. Am J Physiol Cell Physiol 243: C96-C100, 1982.
23. Ho YS. Transgenic models for the study of lung biology and disease. Am J Physiol Lung Cell Mol Physiol 266: L319-L353, 1994. (Pubitemid 24153188)
24. Hummler E, Barker P, Gatzy J, Beermann F, Verdumo C, Schmidt A, Boucher R, Rossier BC. Early death due to defective neonatal lung liquid clearance in α-ENaC-deficient mice. Nat Genet 12: 325-328, 1996. (Pubitemid 26080096)
25. Isakson BE, Lubman RL, Seedorf GJ, Boitano S. Modulation of pulmonary alveolar type II cell phenotype and communication by extracellular matrix and KGF. Am J Physiol Cell Physiol 281: C1291-C1299, 2001. (Pubitemid 32948118)
26. - channels. Am J Physiol Cell Physiol 275: C1610-C1620, 1998.
27. Johnson MD, Bao HF, Helms MN, Chen XJ, Tigue Z, Jain L, Dobbs LG, Eaton DC. Functional ion channels in pulmonary alveolar type I cells support a role for type I cells in lung ion transport. Proc Natl Acad Sci USA 103: 4964-4969, 2006.
28. Junor RW, Benjamin AR, Alexandrou D, Guggino SE, Walters DV. Lack of a role for cyclic nucleotide gated cation channels in lung liquid absorption in fetal sheep. J Physiol 523: 493-502, 2000. (Pubitemid 30137655)
29. Junor RW, Benjamin AR, Alexandrou D, Guggino SE, Walters DV. A novel role for cyclic nucleotide-gated cation channels in lung liquid homeostasis in sheep. J Physiol 520: 255-260, 1999. (Pubitemid 29479158)
30. + conductance of adult rat alveolar type II pneumocytes: evidence for the involvement of cGMP-activated cation channels. J Physiol 536: 693-701, 2001.
31. - fluxes to net ion transport by alveolar epithelium. Respir Physiol 85: 245-256, 1991.
32. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685, 1970.
33. + transport in ATII cells by cAMP: we agree to disagree and do more experiments. Am J Physiol Lung Cell Mol Physiol 278: L233-L238, 2000.
34. Mason RJ, Williams MC, Widdicombe JH, Sanders MJ, Misfeldt DS, Berry LC Jr. Transepithelial transport by pulmonary alveolar type II cells in primary culture. Proc Natl Acad Sci USA 79: 6033-6037, 1982. (Pubitemid 13249973)
35. Matthay MA, Folkesson HG, Clerici C. Lung epithelial fluid transport and the resolution of pulmonary edema. Physiol Rev 82: 569-600, 2002. (Pubitemid 34743332)
36. Matthay MA, Robriquet L, Fang X. Alveolar epithelium: role in lung fluid balance and acute lung injury. Proc Am Thorac Soc 2: 206-213, 2005. (Pubitemid 41500847)
37. 2-adrenergic receptor signaling. Circ Res 94: 1091-1100, 2004.
38. Nielsen S, King LS, Christensen BM, Agre P. Aquaporins in complex tissues. II. Subcellular distribution in respiratory and glandular tissues of rat. Am J Physiol Cell Physiol 273: C1549-C1561, 1997. (Pubitemid 27518076)
39. Nielsen VG, Duvall MD, Baird MS, Matalon S. cAMP activation of chloride and fluid secretion across the rabbit alveolar epithelium. Am J Physiol Lung Cell Mol Physiol 275: L1127-L1133, 1998. (Pubitemid 29029114)
40. Niimi T, Nagashima K, Ward JM, Minoo P, Zimonjic DB, Popescu NC, Kimura S. Claudin-18, a novel downstream target gene for the T/EBP/NKX2.1 homeodomain transcription factor, encodes lung- and stomach-specific isoforms through alternative splicing. Mol Cell Biol 21: 7380-7390, 2001. (Pubitemid 32958540)
41. O'Brodovich H. Epithelial ion transport in the fetal and perinatal lung. Am J Physiol Cell Physiol 261: C555-C564, 1991.
42. O'Brodovich H, Hannam V, Seear M, Mullen JB. Amiloride impairs lung water clearance in newborn guinea pigs. J Appl Physiol 68: 1758-1762, 1990. (Pubitemid 20151909)
43. O'Grady SM, Jiang X, Ingbar DH. Cl- channel activation is necessary for stimulation of Na transport in adult alveolar epithelial cells. Am J Physiol Lung Cell Mol Physiol 278: L239-L244, 2000. (Pubitemid 30131207)
44. Olver RE, Ramsden CA, Strang LB, Walters DV. The role of amiloride-blockable sodium transport in adrenaline-induced lung liquid reabsorption in the fetal lamb. J Physiol 376: 321-340, 1986. (Pubitemid 16058137)
45. Rannels DE, Rannels SR. Influence of the extracellular matrix on type 2 cell differentiation. Chest 96: 165-173, 1989. (Pubitemid 19176434)
46. Rice WR, Conkright JJ, Na CL, Ikegami M, Shannon JM, Weaver TE. Maintenance of the mouse type II cell phenotype in vitro. Am J Physiol Lung Cell Mol Physiol 283: L256-L264, 2002. (Pubitemid 34803981)
47. Russo RM, Lubman RL, Crandall ED. Evidence for amiloride-sensitive sodium channels in alveolar epithelial cells. Am J Physiol Lung Cell Mol Physiol 262: L405-L411, 1992.
48. Sakuma T, Okaniwa G, Nakada T, Nishimura T, Fujimura S, Matthay MA. Alveolar fluid clearance in the resected human lung. Am J Respir Crit Care Med 150: 305-310, 1994. (Pubitemid 24252335)
49. Wang J, Edeen K, Manzer R, Chang Y, Wang S, Chen X, Funk CJ, Cosgrove GP, Fang X, Mason RJ. Differentiated human alveolar epithelial cells and reversibility of their phenotype in vitro. Am J Respir Cell Mol Biol 36: 661-668, 2007. (Pubitemid 46871420)