In vivo biological activity of rocket extracts (Eruca vesicaria subsp. sativa (Miller) Thell) and sulforaphane

Food and Chemical Toxicology

Volumn 50, Issue 5, 2012, Pages 1384-1392

  Villatoro Pulido, M ^a   Font, R ^b   Saha, S ^c   Obregon Cano S ^d   Anter, J ^e   Munoz Serrano A ^e   De Haro Bailon A ^d   Alonso Moraga, A ^e   Del Rio Celestino M ^b  

^a IFAPA CENTRO ALAMEDA DEL OBISPO   (Spain)

^b IFAPA CENTRO EL TORUÑO   (Spain)

^c INSTITUTE OF FOOD RESEARCH   (United Kingdom)

^d INSTITUTO DE AGRICULTURA SOSTENIBLE   (Spain)

^e UNIVERSITY OF CÓRDOBA   (Spain)

Author keywords

Antigenotoxicity; Eruca vesicaria subsp. sativa; Glucosinolates; Isothiocyanates; Life span; Rocket

Indexed keywords

GLUCORAPHANIN; GLUCOSINOLATE; ISOTHIOCYANIC ACID; PLANT EXTRACT; ROCKET EXTRACT; SULFORAPHANE; UNCLASSIFIED DRUG;

ANTIGENOTOXIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; BRASSICACEAE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; DRUG DETERMINATION; DRUG SAFETY; GENOTOXICITY; IN VIVO STUDY; LIFESPAN; NONHUMAN; OXIDATIVE STRESS; PLANT LEAF; ROCKET;

ANIMALS; BRASSICACEAE; DROSOPHILA MELANOGASTER; PLANT EXTRACTS; THIOCYANATES;

DROSOPHILA MELANOGASTER; ERUCA; ERUCA SATIVA;

EID: 84858175466     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2012.02.017     Document Type: Article

References (60)

1. Abraham S.K. Antigenotoxicity of coffee in the Drosophila assay for somatic mutation and recombination. Mutagenesis 1994, 9:383-386.
2. Allen R.G., Tresini M. Oxidative stress and gene regulation. Free Radic. Biol. Med. 2000, 28:463-499.
3. Alonso-Moraga A., Graf U. Genotoxicity testing of antiparasitic nitrofurans in the Drosophila wing somatic mutation and recombination test. Mutagenesis 1989, 4:105-110.
4. Avanesian A., Khodayari B., Felgner J.S., Jafari M. Lamotrigine extends lifespan but compromises health span in Drosophila melanogaster. Biogerontology 2010, 11:45-52.
5. Bahadorani S., Hilliker A.J. Cocoa confers life span extension in Drosophila melanogaster. Nutr. Res. 2008, 28:377-382.
6. Benhar M., Engelberg D., Levitzki A. ROS, stress-activated kinases and stress signaling in cancer. EMBO Rep. 2002, 3:420-425.
7. Bennett R.N., Rosa E.A.S., Mellon F.A., Kroon P.A. Ontogenic profiling of glucosinolates, flavonoids, and other secondary metabolites in Eruca sativa (Salad Rocket), Diplotaxis erucoides (Wall Rocket), Diplotaxis tenuifolia (Wild Rocket), and Bunias orientalis (Turkish Rocket). J. Agric. Food Chem. 2006, 54:4005-4015.
8. Bonnesen C., Eggleston I.M., Hayes J.D. Dietary indoles and isothiocyanate that are generated from cruciferous from vegetables can both stimulate apoptosis and confer protection against DNA damage in human colon cell lines. Cancer Res. 2001, 61:6120-6130.
9. Boyd O., Weng P., Sun X., Alberico T., Laslo M., Obenland D.M., Kern B., Zou S. Nectarine promotes longevity in Drosophila melanogaster. Free Rad. Biol. Med. 2011, 50:1669-1678.
10. Chavous D.A., Jackson F.R., O'Connor C.M. Extension of the Drosophila lifespan by overexpression of a protein repair methyltransferase. Proc. Natl. Acad. Sci. USA 2001, 98:14814-14818.
11. Danielson P.B., Foster J.L.M., McMahill M.M., Smith M.K., Fogleman J.C. Induction by alkaloids and phenobarbital of family 4 cytochrome P450s in Drosophila: evidence for involvement in host plant utilization. Mol. Gen. Genet. 1998, 259:54-59.
12. El Hamss R., Idaomar M., Analla M., Muñoz-Serrano A., Sánchez-Campos J., Alonso-Moraga A. A dose dependent antigenotoxic effect of turmeric. Mutat. Res. 1999, 446:135-139.
13. Fimognari C., Hrelia P. Sulforaphane as a promising molecule for fighting cancer. Mut. Res. 2007, 635:90-104.
14. Fleming J.E., Reveillaud I., Niedzwiecki A. Role of oxidative stress in Drosophila aging. Mutat. Res. 1992, 275:267-279.
15. Fontana L., Partridge L., Longo V.D. Extending healthy life span-from yeast to humans. Science 2010, 328:321-326.
16. Frei H., Würgler F.E. Statistical methods to decide whether mutagenicity test data from Drosophila assays indicate a positive, negative, or inconclusive result. Mutat. Res. 1988, 203:297-308.
17. Galan M.V., Kishan A.A., Silverman A.L. Oral broccoli sprouts for the treatment of Helicobacter pylori infection: a preliminary report. Dig. Dis. Sci. 2004, 49:1088-1090.
18. Grubb C.D., Zipp B.J., Muller J.L., Masuno M.N., Molinski T.F., Abel S. Arabidopsis glucosyltransferase UGT74B1 functions in glucosinolate biosynthesis and auxin homeostasis. Plant. J. 2004, 40:893-908.
19. Kutz A., M€uller A., Hennig P., Kaiser W.M., Piotrowski M., Weiler E.W. A role for nitrilase 3 in the regulation of root morphology in sulphur-starving Arabidopsis thaliana. Plant J. 2002, 30:95-106.
20. Gasper A.V., Traka M., Bacon J.R., Smith J.A., Tailor M.A., Hawkey C.J., Barret D.A., Mithen R. Consuming broccoli does not induce genes associated with xenobiotic metabolism and cell cycle control in human gastric mucosa. J. Nutr. 2007, 137:1718-1724.
21. Chen S., Andreasson E. Update on glucosinolate metabolism and transport. Plant Physiol. Biochem. 2001, 39:743-758.
22. Gill C.I.R., Haldar S., Porter S., Matthews S., Sullivan S., Coulter J., McGlynn H., Rowlnad I. The effect of cruciferous and leguminous sprouts on genotoxicity, in vitro and in vivo. Cancer Epidemiol. Biomarkers Prev. 2004, 13:1199-1205.
23. Graf U., Würgler F.E., Katz A.J., Frei H., Juon H., Hall C.B., Kale P.G. Somatic mutation and recombination test in Drosophila melanogaster. Environ. Mutagen. 1984, 6:153-188.
24. Graf U., Abraham S.K., Guzmán-Rincón J., Würgler F.E. Antigenotoxicity studies in Drosophila melanogaster. Mutat. Res. 1998, 402:203-209.
25. Harman D. Aging: a theory on free radical and radiation chemistry. J. Gerontol. 1956, 11:298-300.
26. Heres-Pulido M.E., Dueñas-García I., Castañeda-Partida L., Santos-Cruz L.F., Vega-Contreras V., Rebollar-Vega R., Gomez-Luna J.C., Durán-Díaz A. Genotoxicity studies of organically grown broccoli (Brassica oleracea var. italica) and its interactions with urethane, methyl methanesulfonate and 4-nitroquinoline-1-oxide genotoxicity in the wing spot test of Drosophila melanogaster. Food Chem. Toxicol. 2010, 48:120-128.
27. Jin J., Koroleva O.A., Gibson T., Swanston J., Magan J., Zhang Y., Rowland I.R., Wagstaff C. Analysis of phytochemical composition and chemoprotective capacity of rocket (Eruca sativa and Diplotaxis tenuifolia) leafy salad following cultivation in different environments. J. Agric. Food Chem. 2009, 57:5227-5234.
28. Jones M.A., Grotewiel M. Drosophila as a model for age-related impairment in locomotor and other behaviors. Exp. Gerontol. 2011, 46:320-325.
29. Juge N., Mithen R.F., Traka M. Molecular basis for chemoprevention by sulforaphane: a comprehensive review. Cell. Mol. Life Sci. 2007, 64:1105-1127.
30. Kassie F., Parzefall W., Musk S., Johnson I., Lamprecht G., Sontag G., Knasmüller S. Genotoxic effects of crude juice from Brassica vegetables and juices extracts from phytopharmaceutical preparations and spices of cruciferous plants origin in bacterial and mammalian cells. Chem. Biol. Interact. 1996, 10:1-16.
31. Kassie F., Knasmüller S. Genotoxic effects of allyl isothiocyanate (AITC) and phenethyl isothiocyanate (PEITC). Chem-Biol. Int. 2000, 127:163-180.
32. Kenyon C.J. The genetics of ageing. Nature 2010, 464:504-512.
33. Kim S.J., Ishii G. Glucosinolate profiles in the seeds, leaves and roots of rocket salad (Eruca sativa Mill.) and anti-oxidative activities of intact plant powder and purified 4-methoxyglucobrassicin. Soil Sci. Plant Nutr. 2006, 52:394-400.
34. Lamy E., Schröder J., Paulus S., Brenk P., Stahl T., Mersch-Sundermann V. Antigenotoxic properties of Eruca sativa (rocket plant), erucin and erysolin in human hepatoma (HepG2) cells towards benzo(a)pyrene and their mode of action. Food Chem. Toxicol. 2008, 46:2415-2421.
35. Li Y.M., Chan H.Y.E., Yao X.Q., Huang Y., Chen Z.Y. Green tea catechins and broccoli reduce fat-induced mortality in Drosophila melanogaster. J. Nutrit. Biochem. 2008, 19:376-383.
36. Lindsley D.L., Zimm G.G. The Genome of Drosophila melanogaster 1992, Academic Press Inc., San Diego, CA.
37. Lustgarten M., Muller F.L., Van Remmen H. An objective appraisal of the free radical theory of aging. Handbook of the Biology of Aging 2011, 177-202. Academic Press, San Diego. seventh ed. E.J. Masoro, S.N. Austad (Eds.).
38. Martin Dietz H., Panigrahi S., Harris R.V. Toxicity of hydrolysis products from 3-butenyl glucosinolate in rats. J. Agric. Food Chem. 1991, 39:311-315.
39. Matusheski N.V., Swarup R., Juvik J.A., Mithen R., Bennet M., Jeffery E.H. Epithiospecifier protein from Brocoli (Brassica oleracea L. ssp. italica) inhibits formation of the anticancer agent sulforaphane. J. Agric. Food Chem. 2006, 54:2069-2076.
40. Melchini A., Costa C., Traka M., Miceli N., Mithen R., DePasquale R., Trovato A. Erucin, a new promising cancer chemopreventive agent from rocket salads, shows anti-proliferative activity on human lung carcinoma A549 cells. Food Chem. Toxicol. 2009, 47:1430-1436.
41. Mithen R. Glucosinolates-biochemistry, genetics and biological activity. Plant Growth Regul. 2001, 34:91-103.
42. Mockett R.J., Sohal R.S. Temperature-dependent trade-offs between longevity and fertility in the Drosophila mutant. Methuselah. Exp. Gerontol. 2006, 41:6566-6573.
43. Okazaki K., Yamagishi M., Son H.Y., Imazawa T., Furakawa F., Nakamura H., Nishikawa A., Masegi T., Hirose M. Simultaneous treatment with benzyl isothiocyanate, a strong bladder promoter, inhibits rat urinary bladder carcinogenesis by N-Butyl-N-(4-Hydroxybutyl)Nitrosamine. Nutrit. Cancer. 2002, 42:211-216.
44. Ren N., Charlton J., Adler P.N. The flare gene, which encodes the AIP1 protein of Drosophila, functions to regulate F-actin disassembly in pupal epidermal cells. Genetics 2007, 176:2223-2234.
45. Romero-Jiménez M., Campos-Sánchez J., Analla M., Muñoz-Serrano A., Alonso-Moraga A. Genotoxicity and antigenotoxicity of some traditional medicinal herbs. Mutat. Res. 2005, 585:147-155.
46. Rose P., Whiteman M., Huang S.H., Haliwell B., Ong C.N. Beta-phenylethyl isothiocyanate-mediated apoptosis in hepatoma HepG2 cells. Cell Mol. Life Sci. 2003, 60:1489-1503.
47. Shapiro T.A., Fahey J.W., Wade K.L., Stephenson K.K., Talalay P. Chemoprotective glucosinolates and isothiocyanates of broccoli sprouts: metabolism and excretion in humans. Cancer Epidemiol. Biomarkers Prev. 2001, 10:501-508.
48. Schumacker P.T. Reactive oxygen species in cancer cells: live by the sword, die by the sword. Cancer cell 2006, 10:175-176.
49. Soh J.W., Hotic S., Arking R. Dietary restriction in Drosophila is dependent on mitochondrial efficiency and constrained by pre-existing extended longevity. Mech. Ageing. Dev. 2007, 128:581-593.
50. Tang L., Zhang Y. Dietary isothiocyanates inhibit the growth of human bladder carcinoma cells. J. Nutr. 2004, 134:2004-2010.
51. Traka M., Gasper A.V., Smith J.A., Hawkey C.J., Bao Y., Mithen R.F. Transcriptome analysis of human colon Caco-2 cells exposed to sulforaphane. J. Nutr. 2005, 135:1865-1872.
52. Trotta V., Calboli F.C., Ziosi M., Guerra D., Pezzoli M.C., David J.R., Cavicchi S. Thermal plasticity in Drosophila melanogaster: a comparison of geographic populations. BMC Evol. Biol. 2006, 6:67.
53. Vázquez-Gómez G., Sánchez-Santos A., Vázquez-Medrano J., Quintanar-Zúñiga R., Monsalvo-Reyes A.C., Piedra-Ibarra E., Dueñas-García I.E., Castañeda-Partida L., Graf U., Heres-Pulido M.E. Sulforaphane modulates the expression of Cyp6a2 and Cyp6g1 in larvae of the ST and HB crosses of the Drosophila wing spot test and is genotoxic in the ST cross. Food Chem. Toxicol. 2010, 48:3333-3339.
54. Villatoro-Pulido M., Font R., De Haro-Bravo M.I., Romero-Jimenez M., Anter J., De Haro Bailon A., Alonso-Moraga A., Del Rio-Celestino M. Modulation of genotoxicity and cytotoxicity by radish grown in metal-contaminated soils. Mutagenesis 2009, 24:51-57.
55. Wathelet J.P., Wagstaffe P., Boenke A. The certification of the total glucosinolate and sulphur contents of three rapeseeds (colza). CRMs 1991, 190:366-367.
56. Yan J., Huen D., Morely T., Johnson G., Gubb D., Roote J., Adler P.N. The multiple-wing-hairs gene encodes a novel GBD-FH3 domain-containing protein that functions both prior to and after wing hair initiation. Genetics 2008, 180:219-228.
57. Yanaka, A., 2005. Dietary Intake of Sulforaphane-Rich Broccoli Sprouts Improves Gastritis in H. pylori-Infected Human Subjects. November 2, 2005 Abstract #3442; Presentation, American Association for Cancer Research Meeting.
58. Yang J., McCart C., Woods D.J., Terhzaz S., Greenwood K.G., Ffrench-Constant R.H., Julian A.T., Dow J.A.T. A Drosophila systems approach to xenobiotic metabolism. Physiol. Genomics 2007, 30:223-231.
59. Yeh C.T., Yen G.C. Effect of sulforaphane on metallothionein expression and induction of apoptosis in human hepatoma HepG2 cells. Carcinogenesis 2005, 26:2138-2148.
60. Zimmering S., Olvera O., Hernández M.E., Cruces M.P., Arceo C., Pimental E. Evidence for a radioprotective effect of chlorophilin in Drosophila. Mutat. Res. 1990, 245:47-49.