Discovery and mutagenicity of a guanidinoformimine lesion as a new intermediate of the oxidative deoxyguanosine degradation pathway

Journal of the American Chemical Society

Volumn 134, Issue 10, 2012, Pages 4925-4930

  Stathis, Dimitrios ^a   Lischke, Ulrike ^a   Koch, Sandra C ^a   Deiml, Christian A ^a   Carell, Thomas ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DEGRADATION PATHWAYS; EXOGENOUS FACTORS; HPLC-MS; MAINTENANCE SYSTEMS; MUTAGENIC PROCESS; MUTAGENICITY; ORGANIC SYNTHESIS; OXIDATIVE DEGRADATION; OXIDATIVE PHOSPHORYLATION; PHYSIOLOGICAL CONDITION; PRIMER EXTENSION; PYROSEQUENCING; REACTIVE OXYGEN SPECIES; STRUCTURE ELUCIDATION;

PHOSPHORYLATION;

BIOMOLECULES;

DEOXYGUANOSINE; GUANIDINE DERIVATIVE; GUANIDINOFORMIMINE; IMIDAZOLE; OXAZOLONE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ARTICLE; DNA DEGRADATION; DNA STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MUTAGENICITY; OXIDATION; OXIDATIVE PHOSPHORYLATION; PYROSEQUENCING; STRUCTURE ANALYSIS; SYNTHESIS;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEOXYGUANOSINE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GUANIDINE; MASS SPECTROMETRY; OXIDATION-REDUCTION; REACTIVE OXYGEN SPECIES;

EID: 84858169563     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja211435d     Document Type: Article

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