Nuclear speckles are involved in nuclear aggregation of PABPN1 and in the pathophysiology of oculopharyngeal muscular dystrophy

Neurobiology of Disease

Volumn 46, Issue 1, 2012, Pages 118-129

  Bengoechea, Rocío ^a   Tapia, Olga ^a   Casafont, Iñigo ^a   Berciano, José ^a   Lafarga, Miguel ^a   Berciano, María T ^a  

^a UNIVERSITY OF CANTABRIA   (Spain)

Author keywords

Intranuclear inclusions; Nuclear body biogenesis; Nuclear speckles; Oculopharyngeal muscular dystrophy; Poly(A) binding protein nuclear 1; Pre mRNA processing; Proteasome inhibition; Skeletal myofibers

Indexed keywords

MESSENGER RNA PRECURSOR; NUCLEAR PROTEIN; POLY(A) BINDING PROTEIN NUCLEAR 1; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CELL NUCLEUS INCLUSION BODY; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HUMAN TISSUE; MALE; MOLECULAR PATHOLOGY; MUSCLE CELL; OCULOPHARYNGEAL MUSCULAR DYSTROPHY; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; RNA PROCESSING;

AGED, 80 AND OVER; CELL NUCLEUS; FEMALE; HUMANS; MIDDLE AGED; MUSCLE FIBERS, SKELETAL; MUSCULAR DYSTROPHY, OCULOPHARYNGEAL; POLY(A)-BINDING PROTEIN I;

EID: 84858155192     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2011.12.052     Document Type: Article

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