Tumour growth inhibition and anti-metastatic activity of a mutated furin-resistant Semaphorin 3E isoform

EMBO Molecular Medicine

Volumn 4, Issue 3, 2012, Pages 234-250

  Casazza, Andrea ^a,b,c   Kigel, Boaz ^d   Maione, Federica ^a   Capparuccia, Lorena ^a   Kessler, Ofra ^d   Giraudo, Enrico ^a   Mazzone, Massimiliano ^b,c   Neufeld, Gera ^d   Tamagnone, Luca ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^c UNIVERSITY OF LEUVEN   (Belgium)

^d TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

Angiogenesis; Metastasis; Plexin; Semaphorin; Tumour growth

Indexed keywords

ANGIOGENESIS INHIBITOR; CHEMOTACTIC FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; FURIN; MEMBRANE RECEPTOR; PLEXIND1; SUNITINIB; UNCLASSIFIED DRUG; UNCLEAVABLE VARIANT OF SEMAPHORIN 3E;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CELL ADHESION; CONTROLLED STUDY; ENDOTHELIUM CELL; EXTRACELLULAR MATRIX; FEMALE; HUMAN; HUMAN CELL; IN VIVO STUDY; METASTASIS; MOUSE; NONHUMAN; PANCREAS ISLET CELL CARCINOMA; PRIORITY JOURNAL; PROTEIN BINDING; SIGNAL TRANSDUCTION; TUMOR CELL; TUMOR GROWTH; VALIDATION PROCESS;

ANIMALS; CELL ADHESION MOLECULES, NEURONAL; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; ENDOTHELIAL CELLS; FEMALE; FURIN; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MICE; MICE, TRANSGENIC; MUTATION; NEOPLASM METASTASIS; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; PROTEIN BINDING; PROTEIN ISOFORMS; SEMAPHORINS; SIGNAL TRANSDUCTION;

EID: 84858114637     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.1002/emmm.201100205     Document Type: Article

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