Neurodegeneration induced by clustering of sialylated glycosylphosphatidylinositols of prion proteins

Journal of Biological Chemistry

Volumn 287, Issue 11, 2012, Pages 7935-7944

  Bate, Clive ^a   Williams, Alun ^b  

^a ROYAL VETERINARY COLLEGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACYL CHAIN; CELLULAR PRION PROTEINS; CROSS-LINKAGE; CULTURED NEURONS; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORS; GPI-ANCHORED PROTEIN; HIGH DENSITY; ISOFORMS; MEMBRANE CHOLESTEROL; MEMBRANE COMPOSITION; NEURODEGENERATION; PHOSPHOLIPASE A; PRION DISEASE; PRION PROTEIN; SIALIC ACIDS; TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIES;

CARBOXYLIC ACIDS; CELL MEMBRANES; CHEMICAL ACTIVATION; CHOLESTEROL; CYTOLOGY; PROTEINS;

NEURODEGENERATIVE DISEASES;

CHOLESTEROL; GLYCOSYLPHOSPHATIDYLINOSITOL; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; PHOSPHOLIPASE A2; PRION PROTEIN; SIALIC ACID; THY 1 ANTIGEN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; EMBRYO; ENZYME ACTIVATION; HYPOTHESIS; MEMBRANE DAMAGE; MOUSE; NERVE CELL CULTURE; NERVE CELL MEMBRANE; NERVE DEGENERATION; NONHUMAN; PATHOPHYSIOLOGY; PRION DISEASE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CROSS LINKING; PROTEIN SYNTHESIS; SYNAPTIC MEMBRANE;

ANIMALS; ANTIGENS, THY-1; CHOLESTEROL; ENZYME ACTIVATION; GLYCOSYLPHOSPHATIDYLINOSITOLS; GPI-LINKED PROTEINS; GROUP IV PHOSPHOLIPASES A2; MICE; MICE, KNOCKOUT; N-ACETYLNEURAMINIC ACID; PRION DISEASES; PRPSC PROTEINS; SYNAPSES;

EID: 84858061475     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.275743     Document Type: Article

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