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Volumn 14, Issue 2, 2012, Pages 247-250

Amniotic fluid stem cell-based models to study the effects of gene mutations and toxicants on male germ cell formation

Author keywords

amniotic fluid; human genetics; infertility; primordial germ cells; reproduction; spermatogenesis; stem cells; toxicity

Indexed keywords

OCTAMER TRANSCRIPTION FACTOR 4; TOXIC SUBSTANCE;

EID: 84858029207     PISSN: 1008682X     EISSN: 17457262     Source Type: Journal    
DOI: 10.1038/aja.2011.170     Document Type: Review
Times cited : (3)

References (75)
  • 1
    • 56449108366 scopus 로고    scopus 로고
    • Stem cells of the germline: The specialized facets of their differentiation program
    • Sassone-Corsi P. Stem cells of the germline: the specialized facets of their differentiation program. Cell Cycle 2008; 7: 3491-2.
    • (2008) Cell Cycle , vol.7 , pp. 3491-3492
    • Sassone-Corsi, P.1
  • 3
    • 77950230499 scopus 로고    scopus 로고
    • Stem cells in mammalian spermatogenesis
    • Yoshida S. Stem cells in mammalian spermatogenesis. Dev Growth Differ 2010; 52: 311-7.
    • (2010) Dev Growth Differ , vol.52 , pp. 311-317
    • Yoshida, S.1
  • 4
  • 5
    • 78751691136 scopus 로고    scopus 로고
    • Human germ cell differentiation from fetal- and adult-derived induced pluripotent stem cells
    • Panula S, Medrano JV, Kee K, Bergström R, Nguyen HN et al. Human germ cell differentiation from fetal- and adult-derived induced pluripotent stem cells. Hum Mol Genet 2011; 20: 752-62.
    • (2011) Hum Mol Genet , vol.20 , pp. 752-762
    • Panula, S.1    Medrano, J.V.2    Kee, K.3    Bergström, R.4    Nguyen, H.N.5
  • 6
    • 0028268992 scopus 로고
    • Estimating the incidence and prevalence and analyzing the correlates of infertility and sterility
    • Menken J, Larsen U. Estimating the incidence and prevalence and analyzing the correlates of infertility and sterility. Ann NY Acad Sci 1994; 709: 249-65. (Pubitemid 24123346)
    • (1994) Annals of the New York Academy of Sciences , vol.709 , pp. 249-265
    • Menken, J.1    Larsen, U.2
  • 7
    • 0037150670 scopus 로고    scopus 로고
    • Sex matters in meiosis
    • DOI 10.1126/science.1071907
    • Hunt PA, Hassold TJ. Sex matters in meiosis. Science 2002; 296: 2181-3. (Pubitemid 34680292)
    • (2002) Science , vol.296 , Issue.5576 , pp. 2181-2183
    • Hunt, P.A.1    Hassold, T.J.2
  • 8
    • 0027475040 scopus 로고
    • Turner syndrome: The case of the missing sex chromosome
    • Zinn AR, Page DC, Fisher EM. Turner syndrome: the case of the missing sex chromosome. Trends Genet 1993; 9: 90-3. (Pubitemid 23062574)
    • (1993) Trends in Genetics , vol.9 , Issue.3 , pp. 90-93
    • Zinn, A.R.1    Page, D.C.2    Fisher, E.M.C.3
  • 9
    • 0033372909 scopus 로고    scopus 로고
    • The X chromosome and ovarian failure
    • DOI 10.1046/j.1365-2265.1999.00926.x
    • Davison RM, Davis CJ, Conway GS. The X chromosome and ovarian failure. Clin Endocrinol 1999; 51: 673-9. (Pubitemid 30050815)
    • (1999) Clinical Endocrinology , vol.51 , Issue.6 , pp. 673-679
    • Davison, R.M.1    Davis, C.J.2    Conway, G.S.3
  • 10
    • 0037130207 scopus 로고    scopus 로고
    • A molecular programme for the specification of germ cell fate in mice
    • DOI 10.1038/nature00927
    • Saitou M, Barton SC, Surani MA. A molecular programme for the specification of germ cell fate in mice. Nature 2002; 418: 293-300. (Pubitemid 34790674)
    • (2002) Nature , vol.418 , Issue.6895 , pp. 293-300
    • Saitou, M.1    Barton, S.C.2    Surani, M.A.3
  • 11
    • 1442336166 scopus 로고    scopus 로고
    • Human STELLAR, NANOG, and GDF3 Genes Are Expressed in Pluripotent Cells and Map to Chromosome 12p13, a Hotspot for Teratocarcinoma
    • Clark AT, Rodriguez RT, Bodnar MS, Abeyta MJ, Cedars MI et al. Human STELLAR, NANOG, and GDF3 genes are expressed in pluripotent cells and map to chromosome 12p13, a hotspot for teratocarcinoma. Stem Cells 2004; 22: 169-79. (Pubitemid 38282632)
    • (2004) Stem Cells , vol.22 , Issue.2 , pp. 169-179
    • Clark, A.T.1    Rodriguez, R.T.2    Bodnar, M.S.3    Abeyta, M.J.4    Cedars, M.I.5    Turek, P.J.6    Firpo, M.T.7    Pera, R.A.R.8
  • 12
    • 0029088061 scopus 로고
    • Diverse spermatogenic defects in humans caused by y chromosome deletions encompassing a novel RNA-binding protein gene
    • Reijo R, Lee TY, Salo P, Alagappan R, Brown LG et al. Diverse spermatogenic defects in humans caused by Y chromosome deletions encompassing a novel RNA-binding protein gene. Nat Genet 1995; 10: 383-93.
    • (1995) Nat Genet , vol.10 , pp. 383-393
    • Reijo, R.1    Lee, T.Y.2    Salo, P.3    Alagappan, R.4    Brown, L.G.5
  • 16
    • 0346562866 scopus 로고    scopus 로고
    • Derivation of embryonic germ cells and male gametes from embryonic stem cells
    • DOI 10.1038/nature02247
    • Geijsen N, Horoschak M, Kim K, Gribnau J, Eggan K et al. Derivation of embryonic germ cells and male gametes from embryonic stem cells. Nature 2004; 427: 148-54. (Pubitemid 38094954)
    • (2004) Nature , vol.427 , Issue.6970 , pp. 148-154
    • Geijsen, N.1    Horoschak, M.2    Kim, K.3    Gribnau, J.4    Eggan, K.5    Daley, G.Q.6
  • 18
    • 33846461167 scopus 로고    scopus 로고
    • Bone morphogenetic proteins induce germ cell differentiation from human embryonic stem cells
    • DOI 10.1089/scd.2006.15.831
    • Kee K, Gonsalves JM, Clark AT, Pera RA. Bonemorphogenetic proteins induce germ cell differentiation from human embryonic stem cells. Stem Cells Dev 2006; 15: 831-7. (Pubitemid 46147855)
    • (2006) Stem Cells and Development , vol.15 , Issue.6 , pp. 831-837
    • Kee, K.1    Gonsalves, J.M.2    Clark, A.T.3    Reijo Pera, R.A.4
  • 19
    • 58049216638 scopus 로고    scopus 로고
    • Isolation of primordial germ cells from differentiating human embryonic stem cells
    • Tilgner K, Atkinson SP, Golebiewska A, Stojkovic M, Lako M et al. Isolation of primordial germ cells from differentiating human embryonic stem cells. Stem Cells 2008; 26: 3075-85.
    • (2008) Stem Cells , vol.26 , pp. 3075-3085
    • Tilgner, K.1    Atkinson, S.P.2    Golebiewska, A.3    Stojkovic, M.4    Lako, M.5
  • 20
    • 59849113310 scopus 로고    scopus 로고
    • A novel approach for the derivation of putative primordial germ cells and Sertoli cells from human embryonic stem cells
    • Bucay N, Yebra M, Cirulli V, Afrikanova I, Kaido T et al. A novel approach for the derivation of putative primordial germ cells and Sertoli cells from human embryonic stem cells. Stem Cells 2009; 27: 68-77.
    • (2009) Stem Cells , vol.27 , pp. 68-77
    • Bucay, N.1    Yebra, M.2    Cirulli, V.3    Afrikanova, I.4    Kaido, T.5
  • 22
    • 65649126708 scopus 로고    scopus 로고
    • Derivation of primordial germ cells from human embryonic and induced pluripotent stem cells is significantly improved by coculture with human fetal gonadal cells
    • Park TS, Galic Z, Conway AE, Lindgren A, van Handel BJ et al. Derivation of primordial germ cells from human embryonic and induced pluripotent stem cells is significantly improved by coculture with human fetal gonadal cells. Stem Cells 2009; 27: 783-95.
    • (2009) Stem Cells , vol.27 , pp. 783-795
    • Park, T.S.1    Galic, Z.2    Conway, A.E.3    Lindgren, A.4    Van Handel, B.J.5
  • 23
    • 78149340082 scopus 로고    scopus 로고
    • Induction of primordial germ cells from mouse induced pluripotent stem cells derived from adult hepatocytes
    • Imamura M, Aoi T, Tokumasu A, Mise N, AbeKet al. Induction of primordial germ cells from mouse induced pluripotent stem cells derived from adult hepatocytes. Mol Reprod Dev 2010; 77: 802-11.
    • (2010) Mol Reprod Dev , vol.77 , pp. 802-811
    • Imamura, M.1    Aoi, T.2    Tokumasu, A.3    Mise, N.4    Abe, K.5
  • 24
    • 80052022935 scopus 로고    scopus 로고
    • Reconstitution of the mouse germ cell specification pathway in culture by pluripotent stem cells
    • Hayashi K, Ohta H, Kurimoto K, Aramaki S, Saitou M. Reconstitution of the mouse germ cell specification pathway in culture by pluripotent stem cells. Cell 2011; 146: 519-32.
    • (2011) Cell , vol.146 , pp. 519-532
    • Hayashi, K.1    Ohta, H.2    Kurimoto, K.3    Aramaki, S.4    Saitou, M.5
  • 25
    • 0028956241 scopus 로고
    • Retinoic acid is a potent growth activator of mouse primordial germ cells in vitro
    • Koshimizu U, Watanabe M, Nakatsuji N. Retinoic acid is a potent growth activator of mouse primordial germ cells in vitro. Dev Biol 1995; 168: 683-5.
    • (1995) Dev Biol , vol.168 , pp. 683-685
    • Koshimizu, U.1    Watanabe, M.2    Nakatsuji, N.3
  • 27
    • 70449651657 scopus 로고    scopus 로고
    • DAZ and BOULE genes modulate primordial germ-cell and haploid gamete formation
    • Kee K, Angeles VT, Flores M, Nguyen HN, Reijo Pera RA. Human DAZL, DAZ and BOULE genes modulate primordial germ-cell and haploid gamete formation. Nature 2009; 462: 222-5.
    • (2009) Nature , vol.462 , pp. 222-225
    • Kee, K.1    Angeles, V.T.2    Flores, M.3    Nguyen, H.N.4    Reijo Pera, R.A.5    Dazl, H.6
  • 28
    • 79956043279 scopus 로고    scopus 로고
    • NANOS3 function in human germ cell development
    • Julaton VT, Reijo Pera RA. NANOS3 function in human germ cell development. Hum Mol Genet 2011; 20: 2238-50.
    • (2011) Hum Mol Genet , vol.20 , pp. 2238-2250
    • Julaton, V.T.1    Reijo Pera, R.A.2
  • 29
    • 64149130904 scopus 로고    scopus 로고
    • Signaling pathways in spermatogonial stem cells and their disruption by toxicants
    • Lucas B, Fields C, Hofmann MC. Signaling pathways in spermatogonial stem cells and their disruption by toxicants. Birth Defects Res C Embryo Today 2009; 87: 35-42.
    • (2009) Birth Defects Res C Embryo Today , vol.87 , pp. 35-42
    • Lucas, B.1    Fields, C.2    Hofmann, M.C.3
  • 30
    • 77953596386 scopus 로고    scopus 로고
    • Use of human embryonic stem cell-based models for male reproductive toxicity screening
    • Krtolica A, Giritharan G. Use of human embryonic stem cell-based models for male reproductive toxicity screening. Syst Biol Reprod Med 2010; 56: 213-21.
    • (2010) Syst Biol Reprod Med , vol.56 , pp. 213-221
    • Krtolica, A.1    Giritharan, G.2
  • 31
    • 77955859275 scopus 로고    scopus 로고
    • Human primordial germ cell formation is diminished by exposure to environmental toxicants acting through the AHR signaling pathway
    • Kee K, Flores M, Cedars MI, Reijo Pera RA. Human primordial germ cell formation is diminished by exposure to environmental toxicants acting through the AHR signaling pathway. Toxicol Sci 2010; 117: 218-24.
    • (2010) Toxicol Sci , vol.117 , pp. 218-224
    • Kee, K.1    Flores, M.2    Cedars, M.I.3    Reijo Pera, R.A.4
  • 32
    • 0037963669 scopus 로고    scopus 로고
    • Oct-4-expressing cells in human amniotic fluid: A new source for stem cell research?
    • DOI 10.1093/humrep/deg279
    • Prusa A, Marton E, Rosner M, Bernaschek G, Hengstschläger M. Oct-4 expressing cells in human amniotic fluid: a new source for stem cell research?HumReprod 2003; 18: 1489-93. (Pubitemid 36840959)
    • (2003) Human Reproduction , vol.18 , Issue.7 , pp. 1489-1493
    • Prusa, A.-R.1    Marton, E.2    Rosner, M.3    Bernaschek, G.4    Hengstschlager, M.5
  • 35
    • 3042634774 scopus 로고    scopus 로고
    • Isolation of human multipotent mesenchymal stem cells from second-trimester amniotic fluid using a novel two-stage culture protocol
    • Tsai MS, Lee JL, Chang YJ, Hwang SM. Isolation of human multipotent mesenchymal stem cells from second-trimester amniotic fluid using a novel two-stage culture protocol. Hum Reprod 2004; 19: 1450-6.
    • (2004) Hum Reprod , vol.19 , pp. 1450-1456
    • Tsai, M.S.1    Lee, J.L.2    Chang, Y.J.3    Hwang, S.M.4
  • 37
    • 33644874940 scopus 로고    scopus 로고
    • Activation of Oct-4 and Rex-1 promoters in human amniotic fluid cells
    • Karlmark KR, Freilinger A, Marton E, Rosner M, Lubec G et al. Activation of Oct-4 and Rex-1 promoters in human amniotic fluid cells. Int J Mol Med 2005; 16: 987-92.
    • (2005) Int J Mol Med , vol.16 , pp. 987-992
    • Karlmark, K.R.1    Freilinger, A.2    Marton, E.3    Rosner, M.4    Lubec, G.5
  • 38
    • 33144474684 scopus 로고    scopus 로고
    • Clonal amniotic fluid-derived stem cells express characteristics of both mesenchymal and neural stem cells
    • Tsai MS, Hwang SM, Tsai YL, Cheng FC, Lee JL et al. Clonal amniotic fluid-derived stem cells express characteristics of both mesenchymal and neural stem cells. Biol Reprod 2006; 74: 545-51.
    • (2006) Biol Reprod , vol.74 , pp. 545-551
    • Tsai, M.S.1    Hwang, S.M.2    Tsai, Y.L.3    Cheng, F.C.4    Lee, J.L.5
  • 39
    • 33646129467 scopus 로고    scopus 로고
    • Molecular and phenotypic characterization of human amniotic fluid cells and their differentiation potential
    • Bossolasco P, Montemurro T, Cova L, Zangrossi S, Calzarossa C et al. Molecular and phenotypic characterization of human amniotic fluid cells and their differentiation potential. Cell Res 2006; 16: 329-36.
    • (2006) Cell Res , vol.16 , pp. 329-336
    • Bossolasco, P.1    Montemurro, T.2    Cova, L.3    Zangrossi, S.4    Calzarossa, C.5
  • 43
    • 65449170084 scopus 로고    scopus 로고
    • Human and murine amniotic c-Kit1Lin2 cells display hematopoietic activity
    • Ditadi A, de Coppi P, Picone O, Gautreau L, Smati R et al. Human and murine amniotic c-Kit1Lin2 cells display hematopoietic activity. Blood 2009; 113: 3953-60.
    • (2009) Blood , vol.113 , pp. 3953-3960
    • Ditadi, A.1    De Coppi, P.2    Picone, O.3    Gautreau, L.4    Smati, R.5
  • 45
    • 77449086372 scopus 로고    scopus 로고
    • Induction of mesenchymal/epithelial marker expression in human amniotic fluid stem cells
    • Siegel N, Valli A, Fuchs C, Rosner M, Hengstschläger M. Induction of mesenchymal/epithelial marker expression in human amniotic fluid stem cells. RBM Online 2009; 19: 838-46.
    • (2009) RBM Online , vol.19 , pp. 838-846
    • Siegel, N.1    Valli, A.2    Fuchs, C.3    Rosner, M.4    Hengstschläger, M.5
  • 46
    • 77955412174 scopus 로고    scopus 로고
    • Contribution of human amniotic fluid stem cells to renal tissue formation depends on mTOR
    • Siegel N, Rosner M, Unbekandt M, Fuchs C, Slabina N et al. Contribution of human amniotic fluid stem cells to renal tissue formation depends on mTOR. Hum Mol Genet 2010; 19: 3320-31.
    • (2010) Hum Mol Genet , vol.19 , pp. 3320-3331
    • Siegel, N.1    Rosner, M.2    Unbekandt, M.3    Fuchs, C.4    Slabina, N.5
  • 47
    • 77949740465 scopus 로고    scopus 로고
    • Protective effect of human amniotic fluid stem cells in an immunodeficient mouse model of acute tubular necrosis
    • Perin L, Sedrakyan S, Giuliani S, DaSacco S, Carraro G et al. Protective effect of human amniotic fluid stem cells in an immunodeficient mouse model of acute tubular necrosis. PLoS ONE 2010; 5: 1-16
    • (2010) PLoS ONE , vol.5 , pp. 1-16
    • Perin, L.1    Sedrakyan, S.2    Giuliani, S.3    Dasacco, S.4    Carraro, G.5
  • 48
    • 77957341499 scopus 로고    scopus 로고
    • Stem cells derived from human amniotic fluid contribute to acute kidney injury recovery
    • Hauser PV, DeFazio R, Bruno S, Sdei S, Grange C et al. Stem cells derived from human amniotic fluid contribute to acute kidney injury recovery. Am J Pathol 2010; 177: 2011-21.
    • (2010) Am J Pathol , vol.177 , pp. 2011-2021
    • Hauser, P.V.1    Defazio, R.2    Bruno, S.3    Sdei, S.4    Grange, C.5
  • 49
    • 77149143851 scopus 로고    scopus 로고
    • Embryoid body formation of human amniotic fluid stem cells depends on mTOR
    • Valli A, Rosner M, Fuchs C, Siegel N, Bishop CE et al. Embryoid body formation of human amniotic fluid stem cells depends on mTOR. Oncogene 2010: 29: 966-77.
    • (2010) Oncogene , vol.29 , pp. 966-977
    • Valli, A.1    Rosner, M.2    Fuchs, C.3    Siegel, N.4    Bishop, C.E.5
  • 50
    • 0032491416 scopus 로고    scopus 로고
    • Embryonic stem cell lines derived from human blastocysts
    • Thomson JA, Itskovitz-Eldor J, Shapiro SS, Waknitz MA, Swiergiel JJ et al. Embryonic stem cell lines derived from human blastocysts. Science 1998; 282: 1145-7. (Pubitemid 28516247)
    • (1998) Science , vol.282 , Issue.5391 , pp. 1145-1147
    • Thomson, J.A.1
  • 51
    • 33746931571 scopus 로고    scopus 로고
    • Ethical issues in using and not using embryonic stem cells
    • DOI 10.1385/SCR:1:4:325, PII SCR14325
    • Kamm FM. Ethical issues in using and not using embryonic stem cells. Stem Cell Rev 2005; 1: 325-30. (Pubitemid 44195968)
    • (2005) Stem Cell Reviews , vol.1 , Issue.4 , pp. 325-330
    • Kamm, F.M.1
  • 52
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • DOI 10.1016/j.cell.2006.07.024, PII S0092867406009767
    • Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006; 126: 663-76. (Pubitemid 44233629)
    • (2006) Cell , vol.126 , Issue.4 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 53
    • 77958569435 scopus 로고    scopus 로고
    • Induced pluripotency: History, mechanisms, and applications
    • Stadtfeld M, Hochedlinger K. Induced pluripotency: history, mechanisms, and applications. Genes Dev 2010; 24: 2239-63.
    • (2010) Genes Dev , vol.24 , pp. 2239-2263
    • Stadtfeld, M.1    Hochedlinger, K.2
  • 54
    • 79952710923 scopus 로고    scopus 로고
    • Induced pluripotent stem cells: A new revolution for clinical neurology?
    • Mattis V, Svendsen CN. Induced pluripotent stem cells: a new revolution for clinical neurology? Lancet Neurol 2011; 10: 383-94.
    • (2011) Lancet Neurol , vol.10 , pp. 383-394
    • Mattis, V.1    Svendsen, C.N.2
  • 55
    • 77955449906 scopus 로고    scopus 로고
    • Epigenetic memory in induced pluripotent stem cells
    • Kim K, Doi A, Wen B, Ng K, Zhao R et al. Epigenetic memory in induced pluripotent stem cells. Nature 2010; 467: 285-90.
    • (2010) Nature , vol.467 , pp. 285-290
    • Kim, K.1    Doi, A.2    Wen, B.3    Ng, K.4    Zhao, R.5
  • 56
    • 77952425747 scopus 로고    scopus 로고
    • Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells
    • Stadtfeld M, Apostolou E, Akutsu H, Fukuda A, Follett P et al. Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells. Nature 2010; 465: 175-81.
    • (2010) Nature , vol.465 , pp. 175-181
    • Stadtfeld, M.1    Apostolou, E.2    Akutsu, H.3    Fukuda, A.4    Follett, P.5
  • 57
    • 78650971216 scopus 로고    scopus 로고
    • Dynamic changes in the copy number of pluripotency and cell proliferation genes in human ESCs and iPSCs during reprogramming and time in culture
    • Laurent LC, Ulitsky I, Slavin I, Tran H, Schork A et al. Dynamic changes in the copy number of pluripotency and cell proliferation genes in human ESCs and iPSCs during reprogramming and time in culture. Cell Stem Cell 2011; 8: 106-18.
    • (2011) Cell Stem Cell , vol.8 , pp. 106-118
    • Laurent, L.C.1    Ulitsky, I.2    Slavin, I.3    Tran, H.4    Schork, A.5
  • 58
    • 77957334627 scopus 로고    scopus 로고
    • Identification and classification of chromosomal aberrations in human induced pluripotent stem cells
    • Mayshar Y, Ben-David U, Lavon N, Biancotti JC, Yakir B et al. Identification and classification of chromosomal aberrations in human induced pluripotent stem cells. Cell Stem Cell 2010; 7: 521-31.
    • (2010) Cell Stem Cell , vol.7 , pp. 521-531
    • Mayshar, Y.1    Ben-David, U.2    Lavon, N.3    Biancotti, J.C.4    Yakir, B.5
  • 59
    • 79952258224 scopus 로고    scopus 로고
    • Somatic coding mutations in human induced pluripotent stem cells
    • Gore A, Li Z, Fung HL, Young JE, Agarwal S et al. Somatic coding mutations in human induced pluripotent stem cells. Nature 2011; 471: 63-7.
    • (2011) Nature , vol.471 , pp. 63-67
    • Gore, A.1    Li, Z.2    Fung, H.L.3    Young, J.E.4    Agarwal, S.5
  • 63
    • 79952898021 scopus 로고    scopus 로고
    • Investigating monogenic and complex diseases with pluripotent stem cells
    • Zhu H, Lensch WM, Cahan P, Daley GQ. Investigating monogenic and complex diseases with pluripotent stem cells. Nat Rev Genet 2011; 12: 266-75.
    • (2011) Nat Rev Genet , vol.12 , pp. 266-275
    • Zhu, H.1    Lensch, W.M.2    Cahan, P.3    Daley, G.Q.4
  • 64
    • 84858038591 scopus 로고    scopus 로고
    • Human amniotic fluid stem cells as a model for functional studies of genes involved in human genetic diseases or oncogenesis
    • Rosner M, Dolznig H, Schipany K, Mikula M, Brandau O et al. Human amniotic fluid stem cells as a model for functional studies of genes involved in human genetic diseases or oncogenesis. Oncotarget 2011; 2: 705-12.
    • (2011) Oncotarget , vol.2 , pp. 705-712
    • Rosner, M.1    Dolznig, H.2    Schipany, K.3    Mikula, M.4    Brandau, O.5
  • 66
    • 39149095271 scopus 로고    scopus 로고
    • PGD-derived human embryonic stem cell lines as a powerful tool for the study of human genetic disorders
    • Ben-Yosef D, Malcov M, Eiges R. PGD-derived human embryonic stem cell lines as a powerful tool for the study of human genetic disorders. Mol Cell Endocrinol 2008; 282: 153-8.
    • (2008) Mol Cell Endocrinol , vol.282 , pp. 153-158
    • Ben-Yosef, D.1    Malcov, M.2    Eiges, R.3
  • 67
    • 50149098605 scopus 로고    scopus 로고
    • Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons
    • Dimos JT, Rodolfa KT, Niakan KK, Weisenthal LM, Mitsumoto H et al. Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons. Science 2008; 321: 1218-21.
    • (2008) Science , vol.321 , pp. 1218-1221
    • Dimos, J.T.1    Rodolfa, K.T.2    Niakan, K.K.3    Weisenthal, L.M.4    Mitsumoto, H.5
  • 68
    • 50549089957 scopus 로고    scopus 로고
    • Disease-specific induced pluripotent stem cells
    • Park IH, Arora N, Huo H, Maherali N, Ahfeldt T et al. Disease-specific induced pluripotent stem cells. Cell 2008; 134: 877-86.
    • (2008) Cell , vol.134 , pp. 877-886
    • Park, I.H.1    Arora, N.2    Huo, H.3    Maherali, N.4    Ahfeldt, T.5
  • 71
    • 77955400436 scopus 로고    scopus 로고
    • Efficient siRNA-mediated prolonged gene silencing in human amniotic fluid stem cells
    • Rosner M, Siegel N, Fuchs C, Slabina N, Dolznig H et al. Efficient siRNA-mediated prolonged gene silencing in human amniotic fluid stem cells. Nat Protoc 2010; 5: 1081-95.
    • (2010) Nat Protoc , vol.5 , pp. 1081-1095
    • Rosner, M.1    Siegel, N.2    Fuchs, C.3    Slabina, N.4    Dolznig, H.5
  • 74
    • 77956188782 scopus 로고    scopus 로고
    • The relevance of the individual genetic background for the toxicokinetics of two significant neurodevelopmental toxicants: Mercury and lead
    • Gundacker C, Gencik M, Hengstschläger M. The relevance of the individual genetic background for the toxicokinetics of two significant neurodevelopmental toxicants: mercury and lead. Mutat Res 2010; 705: 130-40.
    • (2010) Mutat Res , vol.705 , pp. 130-140
    • Gundacker, C.1    Gencik, M.2    Hengstschläger, M.3
  • 75
    • 84864754753 scopus 로고    scopus 로고
    • Proliferation potential of human amniotic fluid stem cells differently responds to mercury and lead exposure
    • 19 November, doi: 10.1007/s00726-011-1154-1
    • Gundacker C, Scheinast M, Damjanovic L, Fuchs C, Rosner M et al. Proliferation potential of human amniotic fluid stem cells differently responds to mercury and lead exposure. Amino Acids; e-pub ahead of print 19 November 2011; doi: 10.1007/s00726-011-1154-1.
    • (2011) Amino Acids; E-pub Ahead of Print
    • Gundacker, C.1    Scheinast, M.2    Damjanovic, L.3    Fuchs, C.4    Rosner, M.5


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