-
1
-
-
0021241398
-
Molecular cloning of a new transforming gene from a chemically transformed human cell line
-
Cooper, C. S., Park, M., Blair, D. G., Tainsky, M. A., Huebner, K., Croce, C. M., and Vande Woude, G. F. (1984) Molecular cloning of a new transforming gene from a chemically transformed human cell line. Nature 311, 29-33 (Pubitemid 14065275)
-
(1984)
Nature
, vol.311
, Issue.5981
, pp. 29-33
-
-
Cooper, C.S.1
Park, M.2
Blair, D.G.3
-
2
-
-
0022472582
-
Mechanism of met oncogene activation
-
Park, M., Dean, M., Cooper, C. S., Schmidt, M., O'Brien, S. J., Blair, D. G., and Vande Woude, G. F. (1986) Mechanism of Met oncogene activation. Cell 45, 895-904 (Pubitemid 16083694)
-
(1986)
Cell
, vol.45
, Issue.6
, pp. 895-904
-
-
Park, M.1
Dean, M.2
Cooper, C.S.3
-
3
-
-
0025805633
-
Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product
-
Bottaro, D. P., Rubin, J. S., Faletto, D. L., Chan, A. M., Kmiecik, T. E., Vande Woude, G. F., and Aaronson, S. A. (1991) Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product. Science 251, 802-804 (Pubitemid 21926175)
-
(1991)
Science
, vol.251
, Issue.4995
, pp. 802-804
-
-
Bottaro, D.P.1
Rubin, J.S.2
Faletto, D.L.3
Chan, A.M.-L.4
Kmiecik, T.E.5
Vande, W.G.F.6
Aaronson, S.A.7
-
4
-
-
0025771101
-
Scatter factor and hepatocyte growth factor are indistinguishable ligands for the MET receptor
-
Naldini, L., Weidner, K. M., Vigna, E., Gaudino, G., Bardelli, A., Ponzetto, C., Narsimhan, R. P., Hartmann, G., Zarnegar, R., Michalopoulos, G. K., et al. (1991) Scatter factor and hepatocyte growth factor are indistinguishable ligands for the MET receptor. EMBO J. 10, 2867-2878 (Pubitemid 21905304)
-
(1991)
EMBO Journal
, vol.10
, Issue.10
, pp. 2867-2878
-
-
Naldini, L.1
Weidner, K.M.2
Vigna, E.3
Gaudino, G.4
Bardelli, A.5
Ponzetto, C.6
Narsimhan, R.P.7
Hartmann, G.8
Zarnegar, R.9
Michalopoulos, G.K.10
Birchmeier, W.11
Comoglio, P.M.12
-
5
-
-
0029809118
-
Branching tubulogenesis but not scatter of Madin-Darby canine kidney cells requires a functional Grb2 binding site in the Met receptor tyrosine kinase
-
DOI 10.1074/jbc.271.36.22211
-
Fournier, T. M., Kamikura, D., Teng, K., and Park, M. (1996) Branching tubulogenesis but not scatter of Madin-Darby canine kidney cells requires a functional Grb2 binding site in the Met receptor tyrosine kinase. J. Biol. Chem. 271, 22211-22217 (Pubitemid 26303855)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.36
, pp. 22211-22217
-
-
Fournier, T.M.1
Kamikura, D.2
Teng, K.3
Park, M.4
-
6
-
-
24944462226
-
CXCR4 and Gab1 cooperate to control the development of migrating muscle progenitor cells
-
DOI 10.1101/gad.346205
-
Vasyutina, E., Stebler, J., Brand-Saberi, B., Schulz, S., Raz, E., and Birchmeier, C. (2005) CXCR4 and Gab1 cooperate to control the development of migrating muscle progenitor cells. Genes Dev. 19, 2187-2198 (Pubitemid 41330320)
-
(2005)
Genes and Development
, vol.19
, Issue.18
, pp. 2187-2198
-
-
Vasyutina, E.1
Stebler, J.2
Brand-Saberi, B.3
Schulz, S.4
Raz, E.5
Birchmeier, C.6
-
7
-
-
1842428601
-
Hepatocyte growth factor/c-met signaling pathway is required for efficient liver regeneration and repair
-
DOI 10.1073/pnas.0306068101
-
Huh, C. G., Factor, V. M., Sánchez, A., Uchida, K., Conner, E. A., and Thorgeirsson, S. S. (2004) Hepatocyte growth factor/c-Met signaling pathway is required for efficient liver regeneration and repair. Proc. Natl. Acad. Sci. U.S.A. 101, 4477-4482 (Pubitemid 38437436)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.13
, pp. 4477-4482
-
-
Huh, C.-G.1
Factor, V.M.2
Sanchez, A.3
Uchida, K.4
Conner, E.A.5
Thorgeirsson, S.S.6
-
8
-
-
3242663197
-
Met provides essential signals for liver regeneration
-
DOI 10.1073/pnas.0403412101
-
Borowiak, M., Garratt, A. N., Wüstefeld, T., Strehle, M., Trautwein, C., and Birchmeier, C. (2004) Met provides essential signals for liver regeneration. Proc. Natl. Acad. Sci. U.S.A. 101, 10608-10613 (Pubitemid 38955789)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.29
, pp. 10608-10613
-
-
Borowiak, M.1
Garratt, A.N.2
Wustefeld, T.3
Strehle, M.4
Trautwein, C.5
Birchmeier, C.6
-
9
-
-
33847292778
-
From Tpr-Met to Met, tumorigenesis and tubes
-
DOI 10.1038/sj.onc.1210201, PII 1210201
-
Peschard, P., and Park, M. (2007) From Tpr-Met to Met, tumorigenesis and tubes. Oncogene 26, 1276-1285 (Pubitemid 46328462)
-
(2007)
Oncogene
, vol.26
, Issue.9
, pp. 1276-1285
-
-
Peschard, P.1
Park, M.2
-
10
-
-
33144462553
-
Amplification of MET may identify a subset of cancers with extreme sensitivity to the selective tyrosine kinase inhibitor PHA-665752
-
Smolen, G. A., Sordella, R., Muir, B., Mohapatra, G., Barmettler, A., Archibald, H., Kim, W. J., Okimoto, R. A., Bell, D. W., Sgroi, D. C., Christensen, J. G., Settleman, J., and Haber, D. A. (2006) Amplification of MET may identify a subset of cancers with extreme sensitivity to the selective tyrosine kinase inhibitor PHA-665752. Proc. Natl. Acad. Sci. U.S.A. 103, 2316-2321
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 2316-2321
-
-
Smolen, G.A.1
Sordella, R.2
Muir, B.3
Mohapatra, G.4
Barmettler, A.5
Archibald, H.6
Kim, W.J.7
Okimoto, R.A.8
Bell, D.W.9
Sgroi, D.C.10
Christensen, J.G.11
Settleman, J.12
Haber, D.A.13
-
11
-
-
34249075147
-
MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling
-
DOI 10.1126/science.1141478
-
Engelman, J. A., Zejnullahu, K., Mitsudomi, T., Song, Y., Hyland, C., Park, J. O., Lindeman, N., Gale, C. M., Zhao, X., Christensen, J., Kosaka, T., Holmes, A. J., Rogers, A. M., Cappuzzo, F., Mok, T., Lee, C., Johnson, B. E., Cantley, L. C., and Jänne, P. A. (2007) MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling. Science 316, 1039-1043 (Pubitemid 46799492)
-
(2007)
Science
, vol.316
, Issue.5827
, pp. 1039-1043
-
-
Engelman, J.A.1
Zejnullahu, K.2
Mitsudomi, T.3
Song, Y.4
Hyland, C.5
Joon, O.P.6
Lindeman, N.7
Gale, C.-M.8
Zhao, X.9
Christensen, J.10
Kosaka, T.11
Holmes, A.J.12
Rogers, A.M.13
Cappuzzo, F.14
Mok, T.15
Lee, C.16
Johnson, B.E.17
Cantley, L.C.18
Janne, P.A.19
-
12
-
-
55449116539
-
Met gene copy number predicts the prognosis for completely resected non-small cell lung cancer
-
Okuda, K., Sasaki, H., Yukiue, H., Yano, M., and Fujii, Y. (2008) Met gene copy number predicts the prognosis for completely resected non-small cell lung cancer. Cancer Sci. 99, 2280-2285
-
(2008)
Cancer Sci.
, vol.99
, pp. 2280-2285
-
-
Okuda, K.1
Sasaki, H.2
Yukiue, H.3
Yano, M.4
Fujii, Y.5
-
13
-
-
60549110433
-
MET increased gene copy number and primary resistance to gefitinib therapy in non-small-cell lung cancer patients
-
Cappuzzo, F., Jänne, P. A., Skokan, M., Finocchiaro, G., Rossi, E., Ligorio, C., Zucali, P. A., Terracciano, L., Toschi, L., Roncalli, M., Destro, A., Incarbone, M., Alloisio, M., Santoro, A., and Varella-Garcia, M. (2009) MET increased gene copy number and primary resistance to gefitinib therapy in non-small-cell lung cancer patients. Ann. Oncol. 20, 298-304
-
(2009)
Ann. Oncol.
, vol.20
, pp. 298-304
-
-
Cappuzzo, F.1
Jänne, P.A.2
Skokan, M.3
Finocchiaro, G.4
Rossi, E.5
Ligorio, C.6
Zucali, P.A.7
Terracciano, L.8
Toschi, L.9
Roncalli, M.10
Destro, A.11
Incarbone, M.12
Alloisio, M.13
Santoro, A.14
Varella-Garcia, M.15
-
14
-
-
54549108740
-
-
(2008) Nature 455, 1061-1068
-
(2008)
Nature
, vol.455
, pp. 1061-1068
-
-
-
15
-
-
0038386452
-
Escape from Cbl-mediated downregulation: A recurrent theme for oncogenic deregulation of receptor tyrosine kinases
-
DOI 10.1016/S1535-6108(03)00136-3
-
Peschard, P., and Park, M. (2003) Escape from Cbl-mediated down-regulation: a recurrent theme for oncogenic deregulation of receptor tyrosine kinases. Cancer Cell 3, 519-523 (Pubitemid 36808646)
-
(2003)
Cancer Cell
, vol.3
, Issue.6
, pp. 519-523
-
-
Peschard, P.1
Park, M.2
-
16
-
-
0024593048
-
v-cbl, an oncogene from a dual-recombinant murine retrovirus that induces early B-lineage lymphomas
-
DOI 10.1073/pnas.86.4.1168
-
Langdon, W. Y., Hartley, J. W., Klinken, S. P., Ruscetti, S. K., and Morse, H. C., 3rd (1989) v-cbl, an oncogene from a dual recombinant murine retrovirus that induces early B-lineage lymphomas. Proc. Natl. Acad. Sci. U.S.A. 86, 1168-1172 (Pubitemid 19061515)
-
(1989)
Proceedings of the National Academy of Sciences of the United States of America
, vol.86
, Issue.4
, pp. 1168-1172
-
-
Langdon, W.Y.1
Hartley, J.W.2
Klinken, S.P.3
Ruscetti, S.K.4
Morse III, H.C.5
-
17
-
-
0029006745
-
Cloning and characterization of cbl-b: A SH3-binding protein with homology to the c-cbl proto-oncogene
-
Keane, M. M., Rivero-Lezcano, O. M., Mitchell, J. A., Robbins, K. C., and Lipkowitz, S. (1995) Cloning and characterization of cbl-b: a SH3-binding protein with homology to the c-cbl proto-oncogene. Oncogene 10, 2367-2377
-
(1995)
Oncogene
, vol.10
, pp. 2367-2377
-
-
Keane, M.M.1
Rivero-Lezcano, O.M.2
Mitchell, J.A.3
Robbins, K.C.4
Lipkowitz, S.5
-
18
-
-
0033519717
-
cbl-3: A new mammalian cbl family protein
-
DOI 10.1038/sj.onc.1202753
-
Keane, M. M., Ettenberg, S. A., Nau, M. M., Banerjee, P., Cuello, M., Penninger, J., and Lipkowitz, S. (1999) Cbl-3: a new mammalian Cbl family protein. Oncogene 18, 3365-3375 (Pubitemid 29286982)
-
(1999)
Oncogene
, vol.18
, Issue.22
, pp. 3365-3375
-
-
Keane, M.M.1
Ettenberg, S.A.2
Nau, M.M.3
Banerjee, P.4
Cuello, M.5
Penninger, J.6
Lipkowitz, S.7
-
19
-
-
0035316576
-
Cbl: Many adaptations to regulate protein tyrosine kinases
-
Thien, C. B., and Langdon, W. Y. (2001) Cbl: many adaptations to regulate protein tyrosine kinases. Nat. Rev. Mol. Cell Biol. 2, 294-307
-
(2001)
Nat. Rev. Mol. Cell Biol.
, vol.2
, pp. 294-307
-
-
Thien, C.B.1
Langdon, W.Y.2
-
20
-
-
0032695793
-
Leucine zipper-mediated homodimerization of the adaptor protein c-Cbl. A role in c-Cbl's tyrosine phosphorylation and its association with epidermal growth factor receptor
-
Bartkiewicz, M., Houghton, A., and Baron, R. (1999) Leucine zipper-mediated homodimerization of the adaptor protein c-Cbl. A role in c-Cbl's tyrosine phosphorylation and its association with epidermal growth factor receptor. J. Biol. Chem. 274, 30887-30895
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 30887-30895
-
-
Bartkiewicz, M.1
Houghton, A.2
Baron, R.3
-
21
-
-
34848888401
-
Structural basis for UBA-mediated dimerization of c-Cbl ubiquitin ligase
-
DOI 10.1074/jbc.M703333200
-
Kozlov, G., Peschard, P., Zimmerman, B., Lin, T., Moldoveanu, T., Mansur-Azzam, N., Gehring, K., and Park, M. (2007) Structural basis for UBA-mediated dimerization of c-Cbl ubiquitin ligase. J. Biol. Chem. 282, 27547-27555 (Pubitemid 47501924)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.37
, pp. 27547-27555
-
-
Kozlov, G.1
Peschard, P.2
Zimmerman, B.3
Lin, T.4
Moldoveanu, T.5
Mansur-Azzam, N.6
Gehring, K.7
Park, M.8
-
22
-
-
34547195241
-
Structural Basis for Ubiquitin-Mediated Dimerization and Activation of the Ubiquitin Protein Ligase Cbl-b
-
DOI 10.1016/j.molcel.2007.06.023, PII S1097276507004133
-
Peschard, P., Kozlov, G., Lin, T., Mirza, I. A., Berghuis, A. M., Lipkowitz, S., Park, M., and Gehring, K. (2007) Structural basis for ubiquitin-mediated dimerization and activation of the ubiquitin protein ligase Cbl-b. Mol. Cell 27, 474-485 (Pubitemid 47126940)
-
(2007)
Molecular Cell
, vol.27
, Issue.3
, pp. 474-485
-
-
Peschard, P.1
Kozlov, G.2
Lin, T.3
Mirza, I.A.4
Berghuis, A.M.5
Lipkowitz, S.6
Park, M.7
Gehring, K.8
-
23
-
-
27444445613
-
c-Cbl and Cbl-b ubiquitin ligases: Substrate diversity and the negative regulation of signalling responses
-
DOI 10.1042/BJ20050892
-
Thien, C. B., and Langdon, W. Y. (2005) c-Cbl and Cbl-b ubiquitin ligases: substrate diversity and the negative regulation of signalling responses. Biochem. J. 391, 153-166 (Pubitemid 41532411)
-
(2005)
Biochemical Journal
, vol.391
, Issue.2
, pp. 153-166
-
-
Thien, C.B.F.1
Langdon, W.Y.2
-
24
-
-
0036911112
-
C-Cbl and Cbl-b regulate T cell responsiveness by promoting ligand-induced TCR down-modulation
-
DOI 10.1038/ni855
-
Naramura, M., Jang, I. K., Kole, H., Huang, F., Haines, D., and Gu, H. (2002) c-Cbl and Cbl-b regulate T cell responsiveness by promoting ligand-induced TCR down-modulation. Nat. Immunol. 3, 1192-1199 (Pubitemid 35469704)
-
(2002)
Nature Immunology
, vol.3
, Issue.12
, pp. 1192-1199
-
-
Naramura, M.1
Jang, I.-K.2
Kole, H.3
Huang, F.4
Haines, D.5
Gu, H.6
-
25
-
-
70350230150
-
c-Cbl and Cbl-b act redundantly to protect osteoclasts from apoptosis and to displace HDAC6 from beta-tubulin, stabilizing microtubules, and podosomes
-
Purev, E., Neff, L., Horne, W. C., and Baron, R. (2009) c-Cbl and Cbl-b act redundantly to protect osteoclasts from apoptosis and to displace HDAC6 from beta-tubulin, stabilizing microtubules, and podosomes. Mol. Biol. Cell 20, 4021-4030
-
(2009)
Mol. Biol. Cell
, vol.20
, pp. 4021-4030
-
-
Purev, E.1
Neff, L.2
Horne, W.C.3
Baron, R.4
-
26
-
-
42349108970
-
A tale of two Cbls: Interplay of c-Cbl and Cbl-b in epidermal growth factor receptor downregulation
-
DOI 10.1128/MCB.01809-07
-
Pennock, S., and Wang, Z. (2008) A tale of two Cbls: interplay of c-Cbl and Cbl-b in epidermal growth factor receptor down-regulation. Mol. Cell. Biol. 28, 3020-3037 (Pubitemid 351556533)
-
(2008)
Molecular and Cellular Biology
, vol.28
, Issue.9
, pp. 3020-3037
-
-
Pennock, S.1
Wang, Z.2
-
27
-
-
0035930341
-
Mutation of the c-Cbl TKB domain binding site on the Met receptor tyrosine kinase converts it into a transforming protein
-
DOI 10.1016/S1097-2765(01)00378-1
-
Peschard, P., Fournier, T. M., Lamorte, L., Naujokas, M. A., Band, H., Langdon, W. Y., and Park, M. (2001) Mutation of the c-Cbl TKB domain binding site on the Met receptor tyrosine kinase converts it into a transforming protein. Mol. Cell 8, 995-1004 (Pubitemid 34031802)
-
(2001)
Molecular Cell
, vol.8
, Issue.5
, pp. 995-1004
-
-
Peschard, P.1
Fournier, T.M.2
Lamorte, L.3
Naujokas, M.A.4
Band, H.5
Langdon, W.Y.6
Park, M.7
-
28
-
-
0035473477
-
Beyond the RING: CBL proteins as multivalent adapters
-
DOI 10.1038/sj.onc.1204781
-
Tsygankov, A. Y., Teckchandani, A. M., Feshchenko, E. A., and Swaminathan, G. (2001) Beyond the RING: CBL proteins as multivalent adapters. Oncogene 20, 6382-6402 (Pubitemid 32977846)
-
(2001)
Oncogene
, vol.20
, Issue.44 REV. ISS. 5
, pp. 6382-6402
-
-
Tsygankov, A.Y.1
Teckchandani, A.M.2
Feshchenko, E.A.3
Swaminathan, G.4
-
29
-
-
27144512084
-
Met/hepatocyte growth factor receptor ubiquitination suppresses transformation and is required for Hrs phosphorylation
-
DOI 10.1128/MCB.25.21.9632-9645.2005
-
Abella, J. V., Peschard, P., Naujokas, M. A., Lin, T., Saucier, C., Urbé, S., and Park, M. (2005) Met/Hepatocyte growth factor receptor ubiquitination suppresses transformation and is required for Hrs phosphorylation. Mol. Cell. Biol. 25, 9632-9645 (Pubitemid 41507861)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.21
, pp. 9632-9645
-
-
Abella, J.V.1
Peschard, P.2
Naujokas, M.A.3
Lin, T.4
Saucier, C.5
Urbe, S.6
Park, M.7
-
30
-
-
0035901973
-
Down-regulation of MET, the receptor for hepatocyte growth factor
-
DOI 10.1038/sj.onc.1204475
-
Hammond, D. E., Urbé, S., Vande Woude, G. F., and Clague, M. J. (2001) Down-regulation of MET, the receptor for hepatocyte growth factor. Oncogene 20, 2761-2770 (Pubitemid 32549833)
-
(2001)
Oncogene
, vol.20
, Issue.22
, pp. 2761-2770
-
-
Hammond, D.E.1
Urbe, S.2
Vande, W.G.F.3
Clague, M.J.4
-
31
-
-
36049051915
-
Oncogenic activation of the Met receptor tyrosine kinase fusion protein, Tpr-Met, involves exclusion from the endocytic degradative pathway
-
DOI 10.1038/sj.onc.1210522, PII 1210522
-
Mak, H. H., Peschard, P., Lin, T., Naujokas, M. A., Zuo, D., and Park, M. (2007) Oncogenic activation of the Met receptor tyrosine kinase fusion protein, Tpr-Met, involves exclusion from the endocytic degradative pathway. Oncogene 26, 7213-7221 (Pubitemid 350085315)
-
(2007)
Oncogene
, vol.26
, Issue.51
, pp. 7213-7221
-
-
Mak, H.H.L.1
Peschard, P.2
Lin, T.3
Naujokas, M.A.4
Zuo, D.5
Park, M.6
-
32
-
-
61549138135
-
Activation of MET by gene amplification or by splice mutations deleting the juxtamembrane domain in primary resected lung cancers
-
Onozato, R., Kosaka, T., Kuwano, H., Sekido, Y., Yatabe, Y., and Mitsudomi, T. (2009) Activation of MET by gene amplification or by splice mutations deleting the juxtamembrane domain in primary resected lung cancers. J. Thorac. Oncol. 4, 5-11
-
(2009)
J. Thorac. Oncol.
, vol.4
, pp. 5-11
-
-
Onozato, R.1
Kosaka, T.2
Kuwano, H.3
Sekido, Y.4
Yatabe, Y.5
Mitsudomi, T.6
-
33
-
-
31544462584
-
Somatic mutations lead to an oncogenic deletion of Met in lung cancer
-
DOI 10.1158/0008-5472.CAN-05-2749
-
Kong-Beltran, M., Seshagiri, S., Zha, J., Zhu, W., Bhawe, K., Mendoza, N., Holcomb, T., Pujara, K., Stinson, J., Fu, L., Severin, C., Rangell, L., Schwall, R., Amler, L., Wickramasinghe, D., and Yauch, R. (2006) Somatic mutations lead to an oncogenic deletion of Met in lung cancer. Cancer Res. 66, 283-289 (Pubitemid 43166034)
-
(2006)
Cancer Research
, vol.66
, Issue.1
, pp. 283-289
-
-
Kong-Beltran, M.1
Seshagiri, S.2
Zha, J.3
Zhu, W.4
Bhawe, K.5
Mendoza, N.6
Holcomb, T.7
Pujara, K.8
Stinson, J.9
Fu, L.10
Severin, C.11
Rangell, L.12
Schwall, R.13
Amier, L.14
Wickramasinghe, D.15
Yauch, R.16
-
34
-
-
13944276728
-
Functional expression and mutations of c-Met and its therapeutic inhibition with SU11274 and small interfering RNA in non-small cell lung cancer
-
DOI 10.1158/0008-5472.CAN-04-2650
-
Ma, P. C., Jagadeeswaran, R., Jagadeesh, S., Tretiakova, M. S., Nallasura, V., Fox, E. A., Hansen, M., Schaefer, E., Naoki, K., Lader, A., Richards, W., Sugarbaker, D., Husain, A. N., Christensen, J. G., and Salgia, R. (2005) Functional expression and mutations of c-Met and its therapeutic inhibition with SU11274 and small interfering RNA in non-small cell lung cancer. Cancer Res. 65, 1479-1488 (Pubitemid 40270177)
-
(2005)
Cancer Research
, vol.65
, Issue.4
, pp. 1479-1488
-
-
Ma, P.C.1
Jagadeeswaran, R.2
Jagadeesh, S.3
Tretiakova, M.S.4
Nallasura, V.5
Fox, E.A.6
Hansen, M.7
Schaefer, E.8
Naoki, K.9
Lader, A.10
Richards, W.11
Sugarbaker, D.12
Husain, A.N.13
Christensen, J.G.14
Salgia, R.15
-
35
-
-
77950859967
-
Gastric cancer cell line Hs746T harbors a splice site mutation of c-Met causing juxtamembrane domain deletion
-
Asaoka, Y., Tada, M., Ikenoue, T., Seto, M., Imai, M., Miyabayashi, K., Yamamoto, K., Yamamoto, S., Kudo, Y., Mohri, D., Isomura, Y., Ijichi, H., Tateishi, K., Kanai, F., Ogawa, S., Omata, M., and Koike, K. (2010) Gastric cancer cell line Hs746T harbors a splice site mutation of c-Met causing juxtamembrane domain deletion. Biochem. Biophys. Res. Commun. 394, 1042-1046
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.394
, pp. 1042-1046
-
-
Asaoka, Y.1
Tada, M.2
Ikenoue, T.3
Seto, M.4
Imai, M.5
Miyabayashi, K.6
Yamamoto, K.7
Yamamoto, S.8
Kudo, Y.9
Mohri, D.10
Isomura, Y.11
Ijichi, H.12
Tateishi, K.13
Kanai, F.14
Ogawa, S.15
Omata, M.16
Koike, K.17
-
36
-
-
0025881838
-
Alternative Splicing Generates Isoforms of the met Receptor Tyrosine Kinase Which Undergo Differential Processing
-
Rodrigues, G. A., Naujokas, M. A., and Park, M. (1991) Alternative splicing generates isoforms of the Met receptor tyrosine kinase which undergo differential processing. Mol. Cell. Biol. 11, 2962-2970 (Pubitemid 21895681)
-
(1991)
Molecular and Cellular Biology
, vol.11
, Issue.6
, pp. 2962-2970
-
-
Rodrigues, G.A.1
Naujokas, M.A.2
Park, M.3
-
37
-
-
0037129827
-
Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
-
RESEARCH0034
-
Vandesompele, J., De Preter, K., Pattyn, F., Poppe, B., Van Roy, N., De Paepe, A., and Speleman, F. (2002) Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol. 3, RESEARCH0034
-
(2002)
Genome Biol.
, vol.3
-
-
Vandesompele, J.1
De Preter, K.2
Pattyn, F.3
Poppe, B.4
Van Roy, N.5
De Paepe, A.6
Speleman, F.7
-
38
-
-
10744228765
-
A Selective Small Molecule Inhibitor of c-Met Kinase Inhibits c-Met-Dependent Phenotypes in Vitro and Exhibits Cytoreductive Antitumor Activity in Vivo
-
Christensen, J. G., Schreck, R., Burrows, J., Kuruganti, P., Chan, E., Le, P., Chen, J., Wang, X., Ruslim, L., Blake, R., Lipson, K. E., Ramphal, J., Do, S., Cui, J. J., Cherrington, J. M., and Mendel, D. B. (2003) A selective small molecule inhibitor of c-Met kinase inhibits c-Met-dependent phenotypes in vitro and exhibits cytoreductive antitumor activity in vivo. Cancer Res. 63, 7345-7355 (Pubitemid 37413476)
-
(2003)
Cancer Research
, vol.63
, Issue.21
, pp. 7345-7355
-
-
Christensen, J.G.1
Schreck, R.2
Burrows, J.3
Kuruganti, P.4
Chan, E.5
Le, P.6
Chen, J.7
Wang, X.8
Ruslim, L.9
Blake, R.10
Lipson, K.E.11
Ramphal, J.12
Do, S.13
Cui, J.J.14
Cherrington, J.M.15
Mendel, D.B.16
-
39
-
-
0037418192
-
Src promotes destruction of c-Cbl: Implications for oncogenic synergy between Src and growth factor receptors
-
DOI 10.1073/pnas.0437945100
-
Bao, J., Gur, G., and Yarden, Y. (2003) Src promotes destruction of c-Cbl: implications for oncogenic synergy between Src and growth factor receptors. Proc. Natl. Acad. Sci. U.S.A. 100, 2438-2443 (Pubitemid 36297517)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.5
, pp. 2438-2443
-
-
Bao, J.1
Gur, G.2
Yarden, Y.3
-
40
-
-
0028351702
-
A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family
-
DOI 10.1016/0092-8674(94)90318-2
-
Ponzetto, C., Bardelli, A., Zhen, Z., Maina, F., dalla Zonca, P., Giordano, S., Graziani, A., Panayotou, G., and Comoglio, P. M. (1994)Amultifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family. Cell 77, 261-271 (Pubitemid 24138623)
-
(1994)
Cell
, vol.77
, Issue.2
, pp. 261-271
-
-
Ponzetto, C.1
Bardelli, A.2
Zhen, Z.3
Maina, F.4
Zonca, P.D.5
Giordano, S.6
Graziani, A.7
Panayotou, G.8
Comoglio, P.M.9
-
41
-
-
0035920225
-
Cbl-b-dependent coordinated degradation of the epidermal growth factor receptor signaling complex
-
Ettenberg, S. A., Magnifico, A., Cuello, M., Nau, M. M., Rubinstein, Y. R., Yarden, Y., Weissman, A. M., and Lipkowitz, S. (2001) Cbl-b-dependent coordinated degradation of the epidermal growth factor receptor signaling complex. J. Biol. Chem. 276, 27677-27684
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 27677-27684
-
-
Ettenberg, S.A.1
Magnifico, A.2
Cuello, M.3
Nau, M.M.4
Rubinstein, Y.R.5
Yarden, Y.6
Weissman, A.M.7
Lipkowitz, S.8
-
42
-
-
33748196233
-
The Cbl family proteins: Ring leaders in regulation of cell signaling
-
DOI 10.1002/jcp.20694
-
Swaminathan, G., and Tsygankov, A. Y. (2006) The Cbl family proteins: ring leaders in regulation of cell signaling. J. Cell. Physiol. 209, 21-43 (Pubitemid 44318665)
-
(2006)
Journal of Cellular Physiology
, vol.209
, Issue.1
, pp. 21-43
-
-
Swaminathan, G.1
Tsygankov, A.Y.2
-
43
-
-
70349329537
-
Cross-talk in Met receptor oncogenesis
-
Lai, A. Z., Abella, J. V., and Park, M. (2009) Cross-talk in Met receptor oncogenesis. Trends Cell Biol. 19, 542-551
-
(2009)
Trends Cell Biol.
, vol.19
, pp. 542-551
-
-
Lai, A.Z.1
Abella, J.V.2
Park, M.3
-
44
-
-
32344451150
-
Regulating the regulator: Negative regulation of Cbl ubiquitin ligases
-
DOI 10.1016/j.tibs.2005.12.004, PII S0968000405003488
-
Ryan, P. E., Davies, G. C., Nau, M. M., and Lipkowitz, S. (2006) Regulating the regulator: negative regulation of Cbl ubiquitin ligases. Trends Biochem. Sci. 31, 79-88 (Pubitemid 43221840)
-
(2006)
Trends in Biochemical Sciences
, vol.31
, Issue.2
, pp. 79-88
-
-
Ryan, P.E.1
Davies, G.C.2
Nau, M.M.3
Lipkowitz, S.4
-
45
-
-
0032478805
-
Fyn, Yes, and Syk phosphorylation sites in c-Cbl map to the same tyrosine residues that become phosphorylated in activated T cells
-
DOI 10.1074/jbc.273.14.8323
-
Feshchenko, E. A., Langdon, W. Y., and Tsygankov, A. Y. (1998) Fyn, Yes, and Syk phosphorylation sites in c-Cbl map to the same tyrosine residues that become phosphorylated in activated T cells. J. Biol. Chem. 273, 8323-8331 (Pubitemid 28168891)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.14
, pp. 8323-8331
-
-
Feshchenko, E.A.1
Langdon, W.Y.2
Tsygankov, A.Y.3
-
46
-
-
0032890156
-
CSF-1 stimulated multiubiquitination of the CSF-1 receptor and of Cbl follows their tyrosine phosphorylation and association with other signaling proteins
-
DOI 10.1002/(SICI)1097-4644(19990101)72:1<119::AID-JCB13>3.0.CO;2-R
-
Wang, Y., Yeung, Y. G., and Stanley, E. R. (1999) CSF-1 stimulated multiubiquitination of the CSF-1 receptor and of Cbl follows their tyrosine phosphorylation and association with other signaling proteins. J. Cell. Biochem. 72, 119-134 (Pubitemid 28541487)
-
(1999)
Journal of Cellular Biochemistry
, vol.72
, Issue.1
, pp. 119-134
-
-
Wang, Y.1
Yeung, Y.-G.2
Stanley, E.R.3
-
47
-
-
0033392493
-
Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1
-
Levkowitz, G., Waterman, H., Ettenberg, S. A., Katz, M., Tsygankov, A. Y., Alroy, I., Lavi, S., Iwai, K., Reiss, Y., Ciechanover, A., Lipkowitz, S., and Yarden, Y. (1999) Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1. Mol. Cell 4, 1029-1040 (Pubitemid 30054908)
-
(1999)
Molecular Cell
, vol.4
, Issue.6
, pp. 1029-1040
-
-
Levkowitz, G.1
Waterman, H.2
Ettenberg, S.A.3
Katz, M.4
Tsygankov, A.Y.5
Alroy, I.6
Lavi, S.7
Iwai, K.8
Reiss, Y.9
Ciechanover, A.10
Lipkowitz, S.11
Yarden, Y.12
-
48
-
-
3142618052
-
Regulation of ubiquitin protein ligase activity in c-Cbl by phosphorylation-induced conformational change and constitutive activation by tyrosine to glutamate point mutations
-
DOI 10.1074/jbc.M404114200
-
Kassenbrock, C. K., and Anderson, S. M. (2004) Regulation of ubiquitin protein ligase activity in c-Cbl by phosphorylation-induced conformational change and constitutive activation by tyrosine to glutamate point mutations. J. Biol. Chem. 279, 28017-28027 (Pubitemid 38900072)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.27
, pp. 28017-28027
-
-
Kassenbrock, C.K.1
Anderson, S.M.2
-
49
-
-
0037162004
-
Isolation and characterization of a novel, transforming allele of the c-Cbl proto-oncogene from a murine macrophage cell line
-
DOI 10.1038/sj/onc/1205510
-
Bisson, S. A., Ujack, E. E., and Robbins, S. M. (2002) Isolation and characterization of a novel, transforming allele of the c-Cbl proto-oncogene from a murine macrophage cell line. Oncogene 21, 3677-3687 (Pubitemid 34620531)
-
(2002)
Oncogene
, vol.21
, Issue.23
, pp. 3677-3687
-
-
Bisson, S.A.1
Ujack, E.E.2
Robbins, S.M.3
-
50
-
-
77953768742
-
Cbl and human myeloid neoplasms: The Cbl oncogene comes of age
-
Kales, S. C., Ryan, P. E., Nau, M. M., and Lipkowitz, S. (2010) Cbl and human myeloid neoplasms: the Cbl oncogene comes of age. Cancer Res. 70, 4789-4794
-
(2010)
Cancer Res.
, vol.70
, pp. 4789-4794
-
-
Kales, S.C.1
Ryan, P.E.2
Nau, M.M.3
Lipkowitz, S.4
-
51
-
-
74949108515
-
Mutations of e3 ubiquitin ligase Cbl family members constitute a novel common pathogenic lesion in myeloid malignancies
-
Makishima, H., Cazzolli, H., Szpurka, H., Dunbar, A., Tiu, R., Huh, J., Muramatsu, H., O'Keefe, C., Hsi, E., Paquette, R. L., Kojima, S., List, A. F., Sekeres, M. A., McDevitt, M. A., and Maciejewski, J. P. (2009) Mutations of e3 ubiquitin ligase Cbl family members constitute a novel common pathogenic lesion in myeloid malignancies. J. Clin. Oncol. 27, 6109-6116
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 6109-6116
-
-
Makishima, H.1
Cazzolli, H.2
Szpurka, H.3
Dunbar, A.4
Tiu, R.5
Huh, J.6
Muramatsu, H.7
O'Keefe, C.8
Hsi, E.9
Paquette, R.L.10
Kojima, S.11
List, A.F.12
Sekeres, M.A.13
McDevitt, M.A.14
Maciejewski, J.P.15
-
52
-
-
77952479240
-
CBL is frequently altered in lung cancers: Its relationship to mutations in MET and EGFR tyrosine kinases
-
Tan, Y. H., Krishnaswamy, S., Nandi, S., Kanteti, R., Vora, S., Onel, K., Hasina, R., Lo, F. Y., El-Hashani, E., Cervantes, G., Robinson, M., Hsu, H. S., Kales, S. C., Lipkowitz, S., Karrison, T., Sattler, M., Vokes, E. E., Wang, Y. C., and Salgia, R. (2010) CBL is frequently altered in lung cancers: its relationship to mutations in MET and EGFR tyrosine kinases. PLoS One 5, e8972
-
(2010)
PLoS One
, vol.5
-
-
Tan, Y.H.1
Krishnaswamy, S.2
Nandi, S.3
Kanteti, R.4
Vora, S.5
Onel, K.6
Hasina, R.7
Lo, F.Y.8
El-Hashani, E.9
Cervantes, G.10
Robinson, M.11
Hsu, H.S.12
Kales, S.C.13
Lipkowitz, S.14
Karrison, T.15
Sattler, M.16
Vokes, E.E.17
Wang, Y.C.18
Salgia, R.19
-
53
-
-
80052048507
-
Mutant Cbl proteins as oncogenic drivers in myeloproliferative disorders
-
Naramura, M., Nadeau, S., Mohapatra, B., Ahmad, G., Mukhopadhyay, C., Sattler, M., Raja, S. M., Natarajan, A., Band, V., and Band, H. (2011) Mutant Cbl proteins as oncogenic drivers in myeloproliferative disorders. Oncotarget 2, 245-250
-
(2011)
Oncotarget
, vol.2
, pp. 245-250
-
-
Naramura, M.1
Nadeau, S.2
Mohapatra, B.3
Ahmad, G.4
Mukhopadhyay, C.5
Sattler, M.6
Raja, S.M.7
Natarajan, A.8
Band, V.9
Band, H.10
-
54
-
-
1642453732
-
Pharmacogenomic Analysis of Cytogenetic Response in Chronic Myeloid Leukemia Patients Treated with Imatinib
-
DOI 10.1158/1078-0432.CCR-0784-3
-
McLean, L. A., Gathmann, I., Capdeville, R., Polymeropoulos, M. H., and Dressman, M. (2004) Pharmacogenomic analysis of cytogenetic response in chronic myeloid leukemia patients treated with imatinib. Clin. Cancer Res. 10, 155-165 (Pubitemid 38114174)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.1 I
, pp. 155-165
-
-
McLean, L.A.1
Gathmann, I.2
Capdeville, R.3
Polymeropoulos, M.H.4
Dressman, M.5
-
55
-
-
0027369598
-
Dimerization mediated through a leucine zipper activates the oncogenic potential of the met receptor tyrosine kinase
-
Rodrigues, G. A., and Park, M. (1993) Dimerization mediated through a leucine zipper activates the oncogenic potential of the Met receptor tyrosine kinase. Mol. Cell. Biol. 13, 6711-6722 (Pubitemid 23321125)
-
(1993)
Molecular and Cellular Biology
, vol.13
, Issue.11
, pp. 6711-6722
-
-
Rodrigues, G.A.1
Park, M.2
-
56
-
-
69149108735
-
Met induces mammary tumors with diverse histologies and is associated with poor outcome and human basal breast cancer
-
Ponzo, M. G., Lesurf, R., Petkiewicz, S., O'Malley, F. P., Pinnaduwage, D., Andrulis, I. L., Bull, S. B., Chughtai, N., Zuo, D., Souleimanova, M., Germain, D., Omeroglu, A., Cardiff, R. D., Hallett, M., and Park, M. (2009) Met induces mammary tumors with diverse histologies and is associated with poor outcome and human basal breast cancer. Proc. Natl. Acad. Sci. U.S.A. 106, 12903-12908
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 12903-12908
-
-
Ponzo, M.G.1
Lesurf, R.2
Petkiewicz, S.3
O'Malley, F.P.4
Pinnaduwage, D.5
Andrulis, I.L.6
Bull, S.B.7
Chughtai, N.8
Zuo, D.9
Souleimanova, M.10
Germain, D.11
Omeroglu, A.12
Cardiff, R.D.13
Hallett, M.14
Park, M.15
-
57
-
-
81755172038
-
An E3 ubiquitin ligase, c-Cbl: A new therapeutic target of lung cancer
-
Lo, F. Y., Tan, Y. H., Cheng, H. C., Salgia, R., and Wang, Y. C. (2011) An E3 ubiquitin ligase, c-Cbl: a new therapeutic target of lung cancer. Cancer 117, 5344-5350
-
(2011)
Cancer
, vol.117
, pp. 5344-5350
-
-
Lo, F.Y.1
Tan, Y.H.2
Cheng, H.C.3
Salgia, R.4
Wang, Y.C.5
|