The neutrophil recombinatorial TCR-like immune receptor is expressed across the entire human life span but repertoire diversity declines in old age

Biochemical and Biophysical Research Communications

Volumn 419, Issue 2, 2012, Pages 309-315

  Fuchs, Tina ^a   Püellmann, Kerstin ^b   Scharfenstein, Olivia ^a   Eichner, Romy ^a   Stobe, Elfi ^a   Becker, Anna ^a   Pechlivanidou, Ioanna ^a   Kzhyshkowska, Julia ^a,c   Gratchev, Alexei ^a,c   Ganser, Arnold ^b   Neumaier, Michael ^a   Beham, Alexander W ^d   Kaminski, Wolfgang E ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b HANNOVER MEDICAL SCHOOL   (Germany)

^c INSTITUTE OF GENERAL PATHOLOGY AND PATHOPHYSIOLOGY   (Russian Federation)

^d UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

Immunology; Immunosenescence; Neutrophils; T cell receptor; Variable immune receptor

Indexed keywords

CD15 ANTIGEN; GRANULOCYTE COLONY STIMULATING FACTOR; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR ALPHA BETA; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BLOOD; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENETIC RECOMBINATION; HUMAN; HUMAN CELL; IMMUNOSENESCENCE; LIFESPAN; MALE; NEUTROPHIL; NEUTROPHIL COUNT; POLARIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STRUCTURE; SENESCENCE;

ADULT; AGED; AGED, 80 AND OVER; AMINO ACID SEQUENCE; FEMALE; HUMANS; LONGEVITY; MALE; MOLECULAR SEQUENCE DATA; NEUTROPHILS; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; V(D)J RECOMBINATION; YOUNG ADULT;

EID: 84857995879     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.02.017     Document Type: Article

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