Telomeric DNA quantity, DNA damage, and heat shock protein gene expression as physiological stress markers in chickens

Poultry Science

Volumn 91, Issue 4, 2012, Pages 829-836

  Sohn, S H ^a   Subramani, V K ^a   Moon, Y S ^a   Jang, I S ^a  

^a Gyeongsang National University   (South Korea)

Author keywords

Chicken; DNA damage; Heat shock protein; Stress marker; Telomere

Indexed keywords

AVES; GALLUS GALLUS;

EID: 84857990852     PISSN: 00325791     EISSN: 15253171     Source Type: Journal    
DOI: 10.3382/ps.2011-01904     Document Type: Article

References (43)

1. Al-Aqil, A., and I. Zulkifli. 2009. Changes in heat shock protein 70 expression and blood characteristics in transported broiler chickens as affected by housing and early age feed restriction. Poult. Sci. 88:1358-1364.
2. Baird, D. M., and D. Kipling. 2004. The extent and significance of telomere loss with age. Ann. N. Y. Acad. Sci. 1019:265-268.
3. Beloor, J., H. K. Kang, Y. J. Kim, V. K. Subramani, I. S. Jang, S. H. Sohn, and Y. S. Moon. 2010. The effect of stocking density on stress related genes and telomeric broiler chickens. Asian-australas. J. Anim. Sci. 23:437-443.
4. Blackburn, E. H. 1991. Telomeres. Trends Biochem. Sci. 16:378-381.
5. Blackburn, E. H., S. Chan, J. Chang, T. B. Fulton, A. Krauskopf, M. McEachern, J. Prescott, J. Roy, C. Smith, and H. Wang. 2000. Molecular manifestations and molecular determinants of telomere capping. Cold Spring Harb. Symp. Quant. Biol. 65:253-263.
6. Cawthon, R. M. 2002. Telomere measurement by quantitative PCR. Nucleic Acids Res. 30:e47.
7. Chen, J. H., C. N. Hales, and S. E. Ozanne. 2007. DNA damage, cellular senescence and organismal ageing: Causal or correlative? Nucleic Acids Res. 35:7417-7428.
8. Cook, M. E. 1991. Nutrition and immune response of the domestic fowl. CRC Crit. Rev. Poult. Biol. 3:167-189.
9. de Jong, I. C., S. van Voorst, D. A. Ehlhardt, and H. J. Blokhuis. 2002. Effects of restricted feeding on physiological stress parameters in growing broiler breeders. Br. Poult. Sci. 43:157-168.
10. de Pauw, E. S. D., N. P. Verwoerd, N. Duinkerken, R. Willemze, A. K. Raap, W. E. Fibbe, and H. J. Tanke. 1998. Assessment of telomere length in hematopoietic interphase cells using in situ hybridization and digital fluorescence microscopy. Cytometry 32:163-169.
11. Delany, M. E., L. M. Daniels, S. E. Swanberg, and H. A. Taylor. 2003. Telomeres in the chicken: Genome stability and chromosome ends. Poult. Sci. 82:917-926.
12. Delany, M. E., A. B. Krupkin, and M. M. Miller. 2000. Organization of telomere sequences in birds: Evidence for arrays of extreme length and for in vivo shortening. Cytogenet. Cell Genet. 90:139-145.
13. Delezie, E., Q. Swennen, J. Buyse, and E. Decuypere. 2007. The effect of feed withdrawal and crating density in transit on metabolism and meat quality of broilers at slaughter weight. Poult. Sci. 86:1414-1423.
14. Epel, E. S., E. H. Blackburn, J. Lin, F. S. Dhabhar, N. E. Adler, J. D. Morrow, and R. M. Cawthon. 2004. Accelerated telomere shortening in response to life stress. Proc. Natl. Acad. Sci. USA 101:17312-17315.
15. Fassbinder-Orth, C. A., and W. H. Karasov. 2006. Effects of feed restriction and realimentation on digestive and immune function in the leghorn chick. Poult. Sci. 85:1449-1456.
16. Gornati, R., E. Papis, R. Simona, T. Genciana, S. Marco, and B. Giovanni. 2004. Rearing density influences the expression of stress-related genes in sea bass (Dicentrarchus labrax, L.). Gene 341:111-118.
17. Harley, C. B., A. B. Futcher, and C. W. Greider. 1990. Telomeres shorten during ageing of human fibroblasts. Nature 345:458-460.
18. Harley, C. B., H. Vaziri, C. M. Counter, and R. C. Allsopp. 1992. The telomere hypothesis of cellular aging. Exp. Gerontol. 27:375-382.
19. Hocking, P. M., M. H. Maxwell, and M. A. Mitchell. 1994. Haematology and blood composition at two ambient temperatures in genetically fat and lean adult broiler breeder females fed ad libitum or restricted throughout life. Br. Poult. Sci. 35:799-807.
20. Iqbal, M., L. L. Probert, N. H. Alhumadi, and H. Klandorf. 1999. Protein glycosylation and advanced glycosylated endproducts (AGEs) accumulation: An avian solution? J. Gerontol. A Biol. Sci. Med. Sci. 54:B171-B176.
21. Kang, S. H., Y. H. Ko, Y. S. Moon, S. H. Sohn, and I. S. Jang. 2011. Effects of the combined stress induced by stocking density and feed restriction on hematological and cytokine parameters as stress indicators in laying hens. Asian-australas. J. Anim. Sci. 24:414-420.
22. Keles, H., A. F. Fidan, I. H. Cigerci, I. Kucukkurt, E. Karadas, and Y. Dundar. 2010. Increased DNA damage and oxidative stress in chickens with natural Marek's disease. Vet. Immunol. Immunopathol. 133:51-58.
23. Kim, Y. J., V. K. Subramani, and S. H. Sohn. 2011. Age prediction in the chickens using telomere quantity by quantitative fluorescence in situ hybridization technique. Asian-australas. J. Anim. Sci. 24:603-609.
24. Kotrschal, A., P. Ilmonen, and D. J. Penn. 2007. Stress impacts telomere dynamics. Biol. Lett. 3:128-130.
25. Ku, H. H., and R. S. Sohal. 1993. Comparison of mitochondrial prooxidant generation and anti-oxidant defenses between rat and pigeon: Possible basis of variation in longevity and metabolic potential. Mech. Ageing Dev. 72:67-76.
26. Livak, K. J., and T. D. Schmittgen. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2-{increment}{increment}CT method. Methods 25:402-408.
27. Mashaly, M. M., G. L. Hendricks III, M. A. Kalama, A. E. Gehad, A. O. Abbas, and P. H. Patterson. 2004. Effect of heat stress on production parameters and immune responses of commercial laying hens. Poult. Sci. 83:889-894.
28. Mashaly, M. M., M. L. Webb, S. L. Youtz, W. B. Roush, and H. B. Graves. 1984. Changes in serum corticosterone concentration of laying hens as a response to increased population density. Poult. Sci. 63:2271-2274.
29. Meng, X., V. Jerome, J. Devin, E. E. Baulieu, and M. G. Catell. 1993. Cloning of chicken hsp90 beta: The only vertebrate hsp90 insensitive to heat shock. Biochem. Biophys. Res. Commun. 190:630-636.
30. Nanda, I., and M. Schmid. 1994. Localization of the telomeric (TTAGGG)n sequence in chicken (Gallus domesticus) chromosomes. Cytogenet. Cell Genet. 65:190-193.
31. O'Callaghan, N., V. Dhillon, P. Thomas, and M. Fenech. 2008. A quantitative real-time PCR method for absolute telomere length. Biotechniques 44:807-809.
32. Puvadolpirod, S., and J. P. Thaxton. 2000. Model of physiological stress in chickens 1. Response parameters. Poult. Sci. 79:363-369.
33. Richter, C., J. W. Park, and B. N. Ames. 1988. Normal oxidative damage to mitochondrial and nuclear DNA is extensive. Proc. Natl. Acad. Sci. USA 85:6465-6467.
34. Richter, T., and C. Proctor. 2007. The role of intracellular peroxide levels on the development and maintenance of telomere-dependent senescence. Exp. Gerontol. 42:1043-1052.
35. Schlesinger, M. J. 1986. Heat shock proteins. J. Cell Biol. 103:321-325.
36. Shanawany, M. M. 1988. Broiler performance under high stocking densities. Br. Poult. Sci. 29:43-52.
37. Slijepcevic, P. 2001. Telomere length measurement by Q-FISH. Methods Cell Sci. 23:17-22.
38. Solovei, I., E. R. Gaginskaya, and H. C. Macgregor. 1994. The arrangement and transcription of telomere DNA sequences at the ends of lampbrush chromosomes of birds. Chromosome Res. 2:460-470.
39. Swanberg, S. E., and M. E. Delany. 2005. Differential expression of genes associated with telomere length homeostasis and oncogenesis in an avian model. Mech. Ageing Dev. 126:1060-1070.
40. Thaxton, J. P., W. A. Dozier III, S. L. Branton, G. W. Morgan, D. W. Miles, W. B. Roush, B. D. Lott, and Y. Vizzier-Thaxton. 2006. Stocking density and physiological adaptive response of broilers. Poult. Sci. 85:819-824.
41. von Zglinicki, T. 2002. Oxidative stress shortens telomeres. Trends Biochem. Sci. 27:339-344.
42. Zimmerman, P. H., A. C. Lindberg, S. J. Pope, E. Glen, J. E. Bolhuis, and C. J. Nicol. 2006. The effect of stocking density, flock size and modified management on laying hen behavior and welfare in a non-cage system. Appl. Anim. Behav. Sci. 101:111-124.
43. Zulkifli, I., M. T. Che Norma, D. A. Israf, and A. R. Omar. 2002. The effect of early-age food restriction on heat shock protein 70 response in heat-stressed female broiler chickens. Br. Poult. Sci. 43:141-145.