Mobilization of endothelial progenitor cells with exercise in healthy individuals: A systematic review

Arquivos Brasileiros de Cardiologia

Volumn 98, Issue 2, 2012, Pages 182-191

  da Silva, Jemima Fuentes Ribeiro ^a   Rocha, Natália Galito ^a   da Nóbrega, Antonio Claudio Lucas ^a  

^a FLUMINENSE FEDERAL UNIVERSITY   (Brazil)

Author keywords

Cell mobilization; Endothelial progenitor cells; Exercise

Indexed keywords

NITRIC OXIDE; VASCULOTROPIN;

AEROBIC EXERCISE; BLOOD SAMPLING; COCHRANE LIBRARY; DRUG BIOAVAILABILITY; ENDOTHELIAL PROGENITOR CELL; EXERCISE INTENSITY; HUMAN; MEDLINE; REVIEW; STEM CELL MOBILIZATION; SYSTEMATIC REVIEW (TOPIC);

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CELL MOVEMENT; ENDOTHELIAL CELLS; EXERCISE; HUMANS; MIDDLE AGED; NITRIC OXIDE; TIME FACTORS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; YOUNG ADULT;

EID: 84857963728     PISSN: 0066782X     EISSN: 16784170     Source Type: Journal    
DOI: None     Document Type: Review

References (39)

1. Asahara T, Murohara T, Sullivan A, Silver M, van der Zee R, Li T, et al. Isolation of putative progenitor endothelial cells for angiogenesis. Science. 1997;275(5302):964-967.
2. Yoder MC, Mead LE, Prater D, Krier TR, Mroueh KN, Li F, et al. Redefining endothelial progenitor cells via clonal analysis and hematopoietic stem/ progenitor cell principals. Blood. 2007;109(5):1801-1809.
3. Beltrami AP, Barlucchi L, Torella D, Baker M, Limana F, Chimenti S, et al. Adult cardiac stem cells are multipotent and support myocardial regeneration. Cell. 2003;114(6):763-776.
4. Shantsila E, Watson T, Lip GY. Endothelial progenitor cells in cardiovascular disorders. J Am Coll Cardiol. 2007;49(7):741-752.
5. Sauter B, Foedinger D, Sterniczky B, Wolff K, Rappersberger K. Immunoelectron microscopic characterization of human dermal lymphatic microvascular endothelial cells. Differential expression of CD31, CD34, and type IV collagen with lymphatic endothelial cells vs blood capillary endothelial cells in normal human skin, lymphangioma, and hemangioma in situ. J Histochem Cytochem. 1998;46(2):165-176.
6. Khan SS, Solomon MA, McCoy JP Jr. Detection of circulating endothelial cells and endothelial progenitor cells by flow cytometry. Cytometry B Clin Cytom. 2005;64(1):1-8.
7. Adams V, Linke A, Breuckmann F, Leineweber K, Erbs S, Krankel N, et al. Circulating progenitor cells decrease immediately after marathon race in advanced-age marathon runners. Eur J Cardiovasc Prev Rehabil. 2008;15(5):602-607.
8. Bonsignore MR, Morici G, Riccioni R, Huertas A, Petrucci E, Veca M, et al. Hemopoietic and angiogenetic progenitors in healthy athletes: different responses to endurance and maximal exercise. J Appl Physiol. 2010;109(1):60-67.
9. Laufs U, Werner N, Link A, Endres M, Wassmann S, Jurgens K, et al. Physical training increases endothelial progenitor cells, inhibits neointima formation, and enhances angiogenesis. Circulation. 2004;109(2):220-226.
10. Asahara T, Takahashi T, Masuda H, Kalka C, Chen D, Iwaguro H, et al. VEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cells. EMBO J. 1999;18(14):3964-3972.
11. Powell TM, Paul JD, Hill JM, Thompson M, Benjamin M, Rodrigo M, et al. Granulocyte colony-stimulating factor mobilizes functional endothelial progenitor cells in patients with coronary artery disease. Arterioscler Thromb Vasc Biol. 2005;25(2):296-301.
12. Kokkinos P, Myers J, Faselis C, Panagiotakos DB, Doumas M, Pittaras A, et al. Exercise capacity and mortality in older men: a 20-year follow-up study. Circulation. 2010;122 (8):790-797.
13. Shi L, Morrison JA, Wiecha J, Horton M, Hayman LL. Healthy lifestyle factors associated with reduced cardiometabolic risk. Br J Nutr. 2011;105(5):747-754
14. Seligman BG, Polanczyk CA, Santos AS, Foppa M, Junges M, Bonzanini L, et al. Intensive practical lifestyle intervention improves endothelial function in metabolic syndrome independent of weight loss: a randomized controlled trial. Metabolism. 2011 Jun 21. [Epub ahead of print].
15. Hill JM, Zalos G, Halcox JP, Schenke WH, Waclawiw MA, Quyyumi AA, et al. Circulating endothelial progenitor cells, vascular function, and cardiovascular risk. N Engl J Med. 2003;348(7):593-600.
16. Giacomini MK, Cook DJ. Users' guides to the medical literature: XXIII. Qualitative research in health care A. Are the results of the study valid? Evidence-Based Medicine Working Group. JAMA. 2000;284(3):357-362.
17. Jenkins NT, Witkowski S, Spangenburg EE, Hagberg JM. Effects of acute and chronic endurance exercise on intracellular nitric oxide in putative endothelial progenitor cells: role of NAPDH oxidase. Am J Physiol Heart Circ Physiol. 2009;297(5):H1798-H1805.
18. Lockard MM, Witkowski S, Jenkins NT, Spangenburg EE, Obisesan TO, Hagberg JM. Thrombin and exercise similarly influence expression of cell cycle genes in cultured putative endothelial progenitor cells. J Appl Physiol. 2010;108(6):1682-1690.
19. Goussetis E, Spiropoulos A, Tsironi M, Skenderi K, Margeli A, Graphakos S, et al. Spartathlon, a 246 kilometer foot race: effects of acute inflammation induced by prolonged exercise on circulating progenitor reparative cells. Blood Cells Mol Dis. 2009;42(3):294-299.
20. Bonsignore MR, Morici G, Santoro A, Pagano M, Cascio L, Bonanno A, et al. Circulating hematopoietic progenitor cells in runners. J Appl Physiol. 2002;93(5):1691-1697.
21. Thijssen DH, Vos JB, Verseyden C, van Zonneveld AJ, Smits P, Sweep FC, et al. Haematopoietic stem cells and endothelial progenitor cells in healthy men: effect of aging and training. Aging Cell. 2006;5(6):495-503.
22. Mobius-Winkler S, Hilberg T, Menzel K, Golla E, Burman A, Schuler G, et al. Time-dependent mobilization of circulating progenitor cells during strenuous exercise in healthy individuals. J Appl Physiol. 2009;107(6):1943-1950.
23. van Craenenbroeck EM, Vrints CJ, Haine SE, Vermeulen K, Goovaerts I, van Tendeloo VF, et al. A maximal exercise bout increases the number of circulating CD34+/KDR+ endothelial progenitor cells in healthy subjects. Relation with lipid profile. J Appl Physiol. 2008;104(4):1006-1013.
24. Yang Z, Wang JM, Chen L, Luo CF, Tang AL, Tao J. Acute exercise-induced nitric oxide production contributes to upregulation of circulating endothelial progenitor cells in healthy subjects. J Hum Hypertens. 2007;21(6):452-460.
25. Thorell D, Borjesson M, Larsson P, Ulfhammer E, Karlsson L, DuttaRoy S. Strenuous exercise increases late outgrowth endothelial cells in healthy subjects. Eur J Appl Physiol. 2009;107(4):481-488.
26. Cubbon RM, Murgatroyd SR, Ferguson C, Bowen TS, Rakobowchuk M, Baliga V, et al. Human exercise-induced circulating progenitor cell mobilization is nitric oxide-dependent and is blunted in South Asian men. Arterioscler Thromb Vasc Biol. 2010;30(4):878-884.
27. Laufs U, Urhausen A, Werner N, Scharhag J, Heitz A, Kissner G, et al. Running exercise of different duration and intensity: effect on endothelial progenitor cells in healthy subjects. Eur J Cardiovasc Prev Rehabil. 2005;12(4):407-414.
28. Bousquet-Santos K, Soares PP, Nobrega AC. Subacute effects of a maximal exercise bout on endothelium-mediated vasodilation in healthy subjects. Braz J Med Biol Res. 2005;38(4):621-627.
29. Adams V, Lenk K, Linke A, Lenz D, Erbs S, Sandri M, et al. Increase of circulating endothelial progenitor cells in patients with coronary artery disease after exercise-induced ischemia. Arterioscler Thromb Vasc Biol. 2004;24(4):684-690.
30. Sandri M, Adams V, Gielen S, Linke A, Lenk K, Krankel N, et al. Effects of exercise and ischemia on mobilization and functional activation of blood-derived progenitor cells in patients with ischemic syndromes: results of 3 randomized studies. Circulation. 2005;111(25):3391-3399.
31. Ostrowski K, Rohde T, Asp S, Schjerling P, Pedersen BK. Pro- and anti-inflammatory cytokine balance in strenuous exercise in humans. J Physiol. 1999;515 (Pt 1):287-291.
32. Aicher A, Zeiher AM, Dimmeler S. Mobilizing endothelial progenitor cells. Hypertension. 2005;45(3):321-325.
33. Margeli A, Skenderi K, Tsironi M, Hantzi E, Matalas AL, Vrettou C, et al. Dramatic elevations of interleukin-6 and acute-phase reactants in athletes participating in the ultradistance foot race spartathlon: severe systemic inflammation and lipid and lipoprotein changes in protracted exercise. J Clin Endocrinol Metab. 2005;90(7):3914-3918.
34. Hoetzer GL, Van Guilder GP, Irmiger HM, Keith RS, Stauffer BL, DeSouza CA. Aging, exercise, and endothelial progenitor cell clonogenic and migratory capacity in men. J Appl Physiol. 2007;102(3):847-852.
35. Padilla J, Harris RA, Rink LD, Wallace JP. Characterization of the brachial artery shear stress following walking exercise. Vasc Med. 2008;13(2):105-111.
36. Nobrega ACL. The subacute effects of exercise: concept, characteristics, and clinical implications. Exerc Sport Sci Rev. 2005;33(2):84-87.
37. Schroder K, Kohnen A, Aicher A, Liehn EA, Buchse T, Stein S, et al. NADPH oxidase Nox2 is required for hypoxia-induced mobilization of endothelial progenitor cells. Circ Res. 2009;105(6):537-544.
38. Lundby C, Gassmann M, Pilegaard H. Regular endurance training reduces the exercise induced HIF-1alpha and HIF-2alpha mRNA expression in human skeletal muscle in normoxic conditions. Eur J Appl Physiol. 2006;96(4):363-369.
39. Hambrecht R, Adams V, Erbs S, Linke A, Krankel N, Shu Y, et al. Regular physical activity improves endothelial function in patients with coronary artery disease by increasing phosphorylation of endothelial nitric oxide synthase. Circulation. 2003;107(25):3152-3158.