Haematopoietic stem cells and endothelial progenitor cells in healthy men: Effect of aging and training

Aging Cell

Volumn 5, Issue 6, 2006, Pages 495-503

  Thijssen, Dick H J ^a   Vos, Joost B ^b   Verseyden, Caroline ^b   Van Zonneveld, Anton Jan ^b   Smits, Paul ^a   Sweep, Fred C G J ^a   Hopman, Maria T E ^a   De Boer, Hetty C ^b  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Aging; Endothelial progenitor cell; Endurance training; Haematopoietic stem cell; single exercise bout

Indexed keywords

ADULT; AGING; ANGIOGENESIS; ARTICLE; BLOOD VESSEL; CARDIOVASCULAR DISEASE; CELL COUNT; CONTROLLED STUDY; ENDOTHELIUM CELL; ENDURANCE; FLUORESCENCE ACTIVATED CELL SORTING; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN EXPERIMENT; IMMOBILIZATION; MALE; NORMAL HUMAN; PHYSICAL ACTIVITY; PRIORITY JOURNAL; RISK FACTOR; SITTING; STATISTICAL ANALYSIS; STEM CELL; TISSUE REPAIR; TRAINING;

ADULT; AGED; AGING; CELL COUNT; CELL PROLIFERATION; ENDOTHELIAL CELLS; EXERCISE THERAPY; EXERCISE TOLERANCE; FLOW CYTOMETRY; HEMATOPOIETIC STEM CELLS; HUMANS; MALE; NEOVASCULARIZATION, PHYSIOLOGIC; PHYSICAL FITNESS; STEM CELLS; UP-REGULATION;

EID: 33751200995     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/j.1474-9726.2006.00242.x     Document Type: Article

References (38)

1. Adams V, Lenk K, Linke A, Lenz D, Erbs S, Sandri M, Tarnok A, Gielen S, Emmrich F, Schuler G, Hambrecht R (2004) Increase of circulating endothelial progenitor cells in patients with coronary artery disease after exercise-induced ischemia. Arterioscler. Thromb. Vasc. Biol. 24, 684-690.
2. Asahara T, Murohara T, Sullivan A, Silver M, van der Zee R, Li T, Witzenbichler B, Schatteman G, Isner JM (1997) Isolation of putative progenitor endothelial cells for angiogenesis. Science 275, 964-967.
3. Asahara T, Takahashi T, Masuda H, Kalka C, Chen D, Iwaguro H, Inai Y, Silver M, Isner JM (1999) VEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cells. EMBO J. 18, 3964-3972.
4. Celermajer DS, Sorensen KE, Spiegelhalter DJ, Georgakopoulos D, Robinson J, Deanfield JE (1994) Aging is associated with endothelial dysfunction in healthy men years before the age-related decline in women. J. Am. Coll. Cardiol. 24, 471-476.
5. Chen MC, Yip HK, Chen CJ, Yang CH, Wu CJ, Cheng CI, Chen YH, Chai HT, Lee CP, Chang HW (2006) No age-related change in circulating endothelial progenitor cells in healthy subjects. Int. Heart J. 47, 95-105.
6. DeSouza CA, Shapiro LF, Clevenger CM, Dinenno FA, Monahan KD, Tanaka H, Seals DR (2000) Regular aerobic exercise prevents and restores age-related declines in endothelium-dependent vasodilation in healthy men. Circulation 102, 1351-1357.
7. Eskurza I, Monahan KD, Robinson JA, Seals DR (2004) Effect of acute and chronic ascorbic acid on flow-mediated dilatation with sedentary and physically active human ageing. J. Physiol. 556, 315-324.
8. Franzoni F, Plantinga Y, Femia FR, Bartolomucci F, Gaudio C, Regoli F, Carpi A, Santoro G, Galetta F (2004) Plasma antioxidant activity and cutaneous microvascular endothelial function in athletes and sedentary controls. Biomed. Pharmacother. 58, 432-436.
9. Gavin TP, Robinson CB, Yeager RC, England JA, Nifong LW, Hickner RC (2004) Angiogenic growth factor response to acute systemic exercise in human skeletal muscle. J. Appl. Physiol. 96, 19-24.
10. Green DJ, Walsh JH, Maiorana A, Burke V, Taylor RR, O'Driscoll JG (2004) Comparison of resistance and conduit vessel nitric oxide-mediated vascular function in vivo: Effects of exercise training. J. Appl. Physiol. 97, 749-755.
11. Heiss C, Keymel S, Niesler U, Ziemann J, Kelm M, Kalka C (2005) Impaired progenitor cell activity in age-related endothelial dysfunction. J. Am. Coll. Cardiol. 45, 1441-1448.
12. Hill JM, Zalos G, Halcox JP, Schenke WH, Waclawiw MA, Quyyumi AA, Finkel T (2003) Circulating endothelial progenitor cells, vascular function, and cardiovascular risk. N. Engl. J. Med. 348, 593-600.
13. Ishizawa K, Kubo H, Yamada M, Kobayashi S, Suzuki T, Mizuno S, Nakamura T, Sasaki H (2004) Hepatocyte growth factor induces angiogenesis in injured lungs through mobilizing endothelial progenitor cells. Biochem. Biophys. Res. Commun. 324, 276-280.
14. Kraus RM, Stallings HW 3rd, Yeager RC, Gavin TP (2004) Circulating plasma VEGF response to exercise in sedentary and endurance-trained men. J. Appl. Physiol. 96, 1445-1450.
15. Laufs U, Urhausen A, Werner N, Scharhag J, Heitz A, Kissner G, Bohm M, Kindermann W, Nickenig G (2005) Running exercise of different duration and intensity: Effect on endothelial progenitor cells in healthy subjects. Eur. J. Cardiovasc. Prev. Rehabil. 12, 407-414.
16. Laufs U, Werner N, Link A, Endres M, Wassmann S, Jurgens K, Miche E, Bohm M, Nickenig G (2004) Physical training increases endothelial progenitor cells, inhibits neointima formation, and enhances angiogenesis. Circulation 109, 220-226.
17. Miyachi M, Kawano H, Sugawara J, Takahashi K, Hayashi K, Yamazaki K, Tabata I, Tanaka H (2004) Unfavorable effects of resistance training on central arterial compliance: A randomized intervention study. Circulation 110, 2858-2863.
18. Monahan KD, Tanaka H, Dinenno FA, Seals DR (2001) Central arterial compliance is associated with age- and habitual exercise-related differences in cardiovagal baroreflex sensitivity. Circulation 104, 1627-1632.
19. Morici G, Zangla D, Santoro A, Pelosi E, Petrucci E, Gioia M, Bonanno A, Profita M, Bellia V, Testa U, Bonsignore MR (2005) Supramaximal exercise mobilizes haematopoietic progenitors and reticulocytes in athletes. Am. J. Physiol. Regul. Integr. Comp. Physiol. 289, R1496-R1503.
20. Orlic D, Kajstura J, Chimenti S, Jakoniuk I, Anderson SM, Li B, Pickel J, McKay R, Nadal-Ginard B, Bodine DM, Leri A, Anversa P (2001) Bone marrow cells regenerate infarcted myocardium. Nature 410, 701-705.
21. Ozuyaman B, Ebner P, Niesler U, Ziemann J, Kleinbongard P, Jax T, Godecke A, Kelm M, Kalka C (2005) Nitric oxide differentially regulates proliferation and mobilization of endothelial progenitor cells but not of hematopoietic stem cells. Thromb. Haemost. 94, 770-772.
22. Paffenbarger RS Jr, Hyde RT, Wing AL, Hsieh CC (1986) Physical activity, all-cause mortality, and longevity of college alumni. N. Engl. J. Med. 314, 605-613.
23. Palange P, Testa U, Huertas A, Calabro L, Antonucci R, Petrucci E, Pelosi E, Pasquini L, Satta A, Morici G, Vignola MA, Bonsignore MR (2006) Circulating haemopoietic and endothelial progenitor cells are decreased in COPD. Eur. Respir. J. 27, 529-541.
24. Rauscher FM, Goldschmidt-Clermont PJ, Davis BH, Wang T, Gregg D, Ramaswami P, Pippen AM, Annex BH, Dong C, Taylor DA (2003) Aging, progenitor cell exhaustion, and atherosclerosis. Circulation 108, 457-463.
25. Rehman J, Li J, Parvathaneni L, Karlsson G, Panchal VR, Temm CJ, Mahenthiran J, March KL (2004) Exercise acutely increases circulating endothelial progenitor cells and monocyte-/macrophage-derived angiogenic cells. J. Am. Coll. Cardiol. 43, 2314-2318.
26. Ryan NA, Zwetsloot KA, Westerkamp LM, Hickner RC, Pofahl WE, Gavin TP (2006) Lower skeletal muscle capillarization and VEGF expression in aged vs. young men. J. Appl. Physiol. 100, 178-185.
27. Sandri M, Adams V, Gielen S, Linke A, Lenk K, Krankel N, Lenz D, Erbs S, Scheinert D, Mohr FW, Schuler G, Hambrecht R (2005) Effects of exercise and ischemia on mobilization and functional activation of blood-derived progenitor cells in patients with ischemic syndromes: Results of 3 randomized studies. Circulation 111, 3391-3399.
28. Schmidt-Lucke C, Rossig L, Fichtlscherer S, Vasa M, Britten M, Kamper U, Dimmeler S, Zeiher AM (2005) Reduced number of circulating endothelial progenitor cells predicts future cardiovascular events: Proof of concept for the clinical importance of endogenous vascular repair. Circulation 111, 2981-2987.
29. Shaffer RG, Greene S, Arshi A, Supple G, Bantly A, Moore JS, Mohler ER 3rd (2006) Flow cytometric measurement of circulating endothelial cells: the effect of age and peripheral arterial disease on baseline levels of mature and progenitor populations. Cytometry B. Clin. Cytom. 70, 56-62.
30. Shintani S, Murohara T, Ikeda H, Ueno T, Honma T, Katoh A, Sasaki K, Shimada T, Oike Y, Imaizumi T (2001) Mobilization of endothelial progenitor cells in patients with acute myocardial infarction. Circulation 103, 2776-2779.
31. Span PN, Grebenchtchikov N, Geurts-Moespot J, Westphal JR, Lucassen AM, Sweep CG (2000) EORTC receptor and biomarker study group report: A sandwich enzyme-linked immunosorbent assay for vascular endothelial growth factor in blood and tumor tissue extracts. Int. J. Biol. Markers 15, 184-191.
32. Steiner S, Niessner A, Ziegler S, Richter B, Seidinger D, Pleiner J, Penka M, Wolzt M, Huber K, Wojta J, Minar E, Kopp CW (2005) Endurance training increases the number of endothelial progenitor cells in patients with cardiovascular risk and coronary artery disease. Atherosclerosis 181, 305-310.
33. Taddei S, Galetta F, Virdis A, Ghiadoni L, Salvetti G, Franzoni F, Giusti C, Salvetti A (2000) Physical activity prevents age-related impairment in nitric oxide availability in elderly athletes. Circulation 101, 2896-2901.
34. Tanaka H, Dinenno FA, Monahan KD, Clevenger CM, DeSouza CA, Seals DR (2000) Aging, habitual exercise, and dynamic arterial compliance. Circulation 102, 1270-1275.
35. Tanaka H, Seals DR, Monahan KD, Clevenger CM, DeSouza CA, Dinenno FA (2002) Regular aerobic exercise and the age-related increase in carotid artery intima-media thickness in healthy men. J. Appl. Physiol. 92, 1458-1464.
36. Urbich C, Dimmeler S (2004) Endothelial progenitor cells: characterization and role in vascular biology. Circ. Res. 95, 343-353.
37. Vasa M, Fichtlscherer S, Aicher A, Adler K, Urbich C, Martin H, Zeiher AM, Dimmeler S (2001) Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease. Circ. Res. 89, E1-E7.
38. Werner N, Kosiol S, Schiegl T, Ahlers P, Walenta K, Link A, Bohm M, Nickenig G (2005) Circulating endothelial progenitor cells and cardiovascular outcomes. N. Engl. J. Med. 353, 999-1007.