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Volumn 11, Issue 5, 2012, Pages 1014-1028

Transcriptional regulation of the c-Myc promoter by NFAT1 involves negative and positive NFAT-responsive elements

Author keywords

c Myc; Gene expression; Gene promoter; NFAT; Transcription factor

Indexed keywords

CALCINEURIN; CALCIUM; MYC PROTEIN; PROTEIN P300; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR NFAT;

EID: 84857957581     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.11.5.19518     Document Type: Article
Times cited : (40)

References (66)
  • 1
    • 36248934318 scopus 로고    scopus 로고
    • The c-myc promoter: Still MysterY and challenge
    • PMID:18037408
    • Wierstra I, Alves J. The c-myc promoter: still MysterY and challenge. Adv Cancer Res 2008; 99:113-333; PMID:18037408; http://dx.doi.org/10.1016/S0065- 230X(07)99004-1.
    • (2008) Adv Cancer Res , vol.99 , pp. 113-333
    • Wierstra, I.1    Alves, J.2
  • 2
    • 33746393644 scopus 로고    scopus 로고
    • Oncogene-dependent tumor suppression: Using the dark side of the force for cancer therapy
    • PMID:16869762
    • Evan GI, Christophorou M, Lawlor EA, Ringshausen I, Prescott J, Dansen T, et al. Oncogene-dependent tumor suppression: using the dark side of the force for cancer therapy. Cold Spring Harb Symp Quant Biol 2005; 70:263-73; PMID:16869762; http://dx.doi. org/10.1101/sqb.2005.70.054.
    • (2005) Cold Spring Harb Symp Quant Biol , vol.70 , pp. 263-273
    • Evan, G.I.1    Christophorou, M.2    Lawlor, E.A.3    Ringshausen, I.4    Prescott, J.5    Dansen, T.6
  • 3
    • 33845187907 scopus 로고    scopus 로고
    • Global mapping of c-Myc binding sites and target gene networks in human B cells
    • PMID:17093053
    • Zeller KI, Zhao X, Lee CW, Chiu KP, Yao F, Yustein JT, et al. Global mapping of c-Myc binding sites and target gene networks in human B cells. Proc Natl Acad Sci USA 2006; 103:17834-9; PMID:17093053; http:// dx.doi.org/10.1073/ pnas.0604129103.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 17834-17839
    • Zeller, K.I.1    Zhao, X.2    Lee, C.W.3    Chiu, K.P.4    Yao, F.5    Yustein, J.T.6
  • 4
    • 52149094807 scopus 로고    scopus 로고
    • How the c-myc promoter works and why it sometimes does not
    • PMID:18648001
    • Levens D. How the c-myc promoter works and why it sometimes does not. J Natl Cancer Inst Monogr 2008:41-3; PMID:18648001; http://dx.doi. org/10.1093/jncimonographs/lgn004.
    • (2008) J Natl Cancer Inst Monogr , pp. 41-43
    • Levens, D.1
  • 5
    • 33748192942 scopus 로고    scopus 로고
    • The Myc oncoprotein as a therapeutic target for human cancer
    • PMID:16934487
    • Vita M, Henriksson M. The Myc oncoprotein as a therapeutic target for human cancer. Semin Cancer Biol 2006; 16:318-30; PMID:16934487; http://dx.doi. org/10.1016/j.semcancer.2006.07.015.
    • (2006) Semin Cancer Biol , vol.16 , pp. 318-330
    • Vita, M.1    Henriksson, M.2
  • 6
    • 79952859424 scopus 로고    scopus 로고
    • You Don't Muck with MYC
    • PMID:20882108
    • Levens D. You Don't Muck with MYC. Genes Cancer 2010; 1:547-54; PMID:20882108; http://dx.doi. org/10.1177/1947601910377492.
    • (2010) Genes Cancer , vol.1 , pp. 547-554
    • Levens, D.1
  • 7
    • 0141483523 scopus 로고    scopus 로고
    • Transcriptional regulation by calcium, calcineurin and NFAT
    • PMID:12975316
    • Hogan PG, Chen L, Nardone J, Rao A. Transcriptional regulation by calcium, calcineurin and NFAT. Genes Dev 2003; 17:2205-32; PMID:12975316; http:// dx.doi.org/10.1101/gad.1102703.
    • (2003) Genes Dev , vol.17 , pp. 2205-2232
    • Hogan, P.G.1    Chen, L.2    Nardone, J.3    Rao, A.4
  • 8
    • 0036305450 scopus 로고    scopus 로고
    • T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes
    • PMID:12055628
    • Avni O, Lee D, Macian F, Szabo SJ, Glimcher LH, Rao AT. T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes. Nat Immunol 2002; 3:643-51; PMID:12055628.
    • (2002) Nat Immunol , vol.3 , pp. 643-651
    • Avni, O.1    Lee, D.2    Macian, F.3    Szabo, S.J.4    Glimcher, L.H.5    Rao, A.T.6
  • 9
    • 34147206547 scopus 로고    scopus 로고
    • A modular enhancer is differentially regulated by GATA and NFAT elements that direct different tissue-specific patterns of nucleosome positioning and inducible chromatin remodeling
    • PMID:17283044
    • Bert AG, Johnson BV, Baxter EW, Cockerill PN. A modular enhancer is differentially regulated by GATA and NFAT elements that direct different tissue-specific patterns of nucleosome positioning and inducible chromatin remodeling. Mol Cell Biol 2007; 27:2870-85; PMID:17283044; http://dx.doi.org/10. 1128/ MCB.02323-.
    • (2007) Mol Cell Biol , vol.27 , pp. 2870-2885
    • Bert, A.G.1    Johnson, B.V.2    Baxter, E.W.3    Cockerill, P.N.4
  • 10
    • 4444294851 scopus 로고    scopus 로고
    • Granulocyte-macrophage colony-stimulating factor enhancer activation requires cooperation between NFAT and AP-1 elements and is associated with extensive nucleosome reorganization
    • PMID:15340054
    • Johnson BV, Bert AG, Ryan GR, Condina A, Cockerill PN. Granulocyte-macrophage colony-stimulating factor enhancer activation requires cooperation between NFAT and AP-1 elements and is associated with extensive nucleosome reorganization. Mol Cell Biol 2004; 24:7914-30; PMID:15340054; http://dx.doi. org/10.1128/MCB.24.18.7914-30.2004.
    • (2004) Mol Cell Biol , vol.24 , pp. 7914-7930
    • Johnson, B.V.1    Bert, A.G.2    Ryan, G.R.3    Condina, A.4    Cockerill, P.N.5
  • 11
    • 20644466433 scopus 로고    scopus 로고
    • NFAT proteins: Key regulators of T-cell development and function
    • PMID:15928679
    • Macian F. NFAT proteins: key regulators of T-cell development and function. Nat Rev Immunol 2005; 5:472-84; PMID:15928679; http://dx.doi. org/10.1038/nri1632.
    • (2005) Nat Rev Immunol , vol.5 , pp. 472-484
    • Macian, F.1
  • 12
    • 0030973579 scopus 로고    scopus 로고
    • Transcription factors of the NFAT family: Regulation and function
    • PMID:9143705
    • Rao A, Luo C, Hogan PG. Transcription factors of the NFAT family: regulation and function. Annu Rev Immunol 1997; 15:707-47; PMID:9143705; http:// dx.doi.org/10.1146/annurev.immunol.15.1.707.
    • (1997) Annu Rev Immunol , vol.15 , pp. 707-747
    • Rao, A.1    Luo, C.2    Hogan, P.G.3
  • 13
    • 0023821516 scopus 로고
    • Identification of a putative regulator of early T cell activation genes
    • PMID:3260404
    • Shaw JP, Utz PJ, Durand DB, Toole JJ, Emmel EA, Crabtree GR. Identification of a putative regulator of early T cell activation genes. Science 1988; 241:202-5; PMID:3260404; http://dx.doi.org/10.1126/science. 3260404.
    • (1988) Science , vol.241 , pp. 202-205
    • Shaw, J.P.1    Utz, P.J.2    Durand, D.B.3    Toole, J.J.4    Emmel, E.A.5    Crabtree, G.R.6
  • 14
    • 16844382568 scopus 로고    scopus 로고
    • NFAT transcription factors: From cell cycle to tumor development
    • PMID:15761612
    • Viola JP, Carvalho LD, Fonseca BP, Teixeira LK. NFAT transcription factors: from cell cycle to tumor development. Braz J Med Biol Res 2005; 38:335-44; PMID:15761612; http://dx.doi.org/10.1590/S0100-879X2005000300003.
    • (2005) Braz J Med Biol Res , vol.38 , pp. 335-344
    • Viola, J.P.1    Carvalho, L.D.2    Fonseca, B.P.3    Teixeira, L.K.4
  • 15
    • 0036864625 scopus 로고    scopus 로고
    • NFATc2-mediated repression of cyclin-dependent kinase 4 expression
    • PMID:12453415
    • Baksh S, Widlund HR, Frazer-Abel AA, Du J, Fosmire S, Fisher DE, et al. NFATc2-mediated repression of cyclin-dependent kinase 4 expression. Mol Cell 2002; 10:1071-81; PMID:12453415; http://dx.doi. org/10.1016/S1097-2765(02)00701- 3.
    • (2002) Mol Cell , vol.10 , pp. 1071-1081
    • Baksh, S.1    Widlund, H.R.2    Frazer-Abel, A.A.3    Du, J.4    Fosmire, S.5    Fisher, D.E.6
  • 16
    • 0035809312 scopus 로고    scopus 로고
    • Selective inhibition of vascular endothelial growth factor-mediated angiogenesis by cyclosporin A: Roles of the nuclear factor of activated T cells and cyclooxygenase 2
    • PMID:11238591
    • Hernández GL, Volpert OV, Iñiguez MA, Lorenzo E, Martínez-Martínez S, Grau R, et al. Selective inhibition of vascular endothelial growth factor-mediated angiogenesis by cyclosporin A: roles of the nuclear factor of activated T cells and cyclooxygenase 2. J Exp Med 2001; 193:607-20; PMID:11238591; http://dx.doi. org/10.1084/jem.193.5.607.
    • (2001) J Exp Med , vol.193 , pp. 607-620
    • Hernández, G.L.1    Volpert, O.V.2    Iñiguez, M.A.3    Lorenzo, E.4    Martínez-Martínez, S.5    Grau, R.6
  • 17
    • 0036308285 scopus 로고    scopus 로고
    • The role of NFAT transcription factors in integrin-mediated carcinoma invasion
    • PMID:12080349
    • Jauliac S, López-Rodriguez C, Shaw LM, Brown LF, Rao A, Toker A. The role of NFAT transcription factors in integrin-mediated carcinoma invasion. Nat Cell Biol 2002; 4:540-4; PMID:12080349; http://dx.doi. org/10.1038/ncb816.
    • (2002) Nat Cell Biol , vol.4 , pp. 540-544
    • Jauliac, S.1    López-Rodriguez, C.2    Shaw, L.M.3    Brown, L.F.4    Rao, A.5    Toker, A.6
  • 19
    • 77249176619 scopus 로고    scopus 로고
    • NFAT-induced histone acetylation relay switch promotes c-Myc-dependent growth in pancreatic cancer cells
    • PMID:19900447
    • Köenig A, Linhart T, Schlengemann K, Reutlinger K, Wegele J, Adler G, et al. NFAT-induced histone acetylation relay switch promotes c-Myc-dependent growth in pancreatic cancer cells. Gastroenterology 2010; 138:1189-99; PMID:19900447; http://dx.doi. org/10.1053/j.gastro.2009.10.045.
    • (2010) Gastroenterology , vol.138 , pp. 1189-1199
    • Köenig, A.1    Linhart, T.2    Schlengemann, K.3    Reutlinger, K.4    Wegele, J.5    Adler, G.6
  • 20
    • 78149441344 scopus 로고    scopus 로고
    • An epigenetic chromatin remodeling role for NFATc1 in transcriptional regulation of growth and survival genes in diffuse large B-cell lymphomas
    • PMID:20664054
    • Pham LV, Tamayo AT, Li C, Bueso-Ramos C, Ford RJ. An epigenetic chromatin remodeling role for NFATc1 in transcriptional regulation of growth and survival genes in diffuse large B-cell lymphomas. Blood 2010; 116:3899-906; PMID:20664054; http://dx.doi. org/10.1182/blood-2009-12-257378.
    • (2010) Blood , vol.116 , pp. 3899-3906
    • Pham, L.V.1    Tamayo, A.T.2    Li, C.3    Bueso-Ramos, C.4    Ford, R.J.5
  • 21
    • 77956258205 scopus 로고    scopus 로고
    • Sequential activation of NFAT and c-Myc transcription factors mediates the TGFbeta switch from a suppressor to a promoter of cancer cell proliferation
    • PMID:20516082
    • Singh G, Singh SK, König A, Reutlinger K, Nye MD, Adhikary T, et al. Sequential activation of NFAT and c-Myc transcription factors mediates the TGFbeta switch from a suppressor to a promoter of cancer cell proliferation. J Biol Chem 2010; 285:27241- 50; PMID:20516082; http://dx.doi.org/10.1074/jbc. M110.100438.
    • (2010) J Biol Chem , vol.285 , pp. 27241-27250
    • Singh, G.1    Singh, S.K.2    König, A.3    Reutlinger, K.4    Nye, M.D.5    Adhikary, T.6
  • 22
    • 0025058475 scopus 로고
    • Coordinate expression of src family protooncogenes in T cell activation and its modulation by cyclosporine
    • PMID:2104905
    • Furue M, Katz SI, Kawakami Y, Kawakami T. Coordinate expression of src family protooncogenes in T cell activation and its modulation by cyclosporine. J Immunol 1990; 144:736-9; PMID:2104905.
    • (1990) J Immunol , vol.144 , pp. 736-739
    • Furue, M.1    Katz, S.I.2    Kawakami, Y.3    Kawakami, T.4
  • 23
    • 0026652809 scopus 로고
    • Independent regulation of c-myc, B-myb and c-myb gene expression by inducers and inhibitors of proliferation in human B lymphocytes
    • PMID:1376749
    • Golay J, Cusmano G, Introna M. Independent regulation of c-myc, B-myb and c-myb gene expression by inducers and inhibitors of proliferation in human B lymphocytes. J Immunol 1992; 149:300-8; PMID:1376749.
    • (1992) J Immunol , vol.149 , pp. 300-308
    • Golay, J.1    Cusmano, G.2    Introna, M.3
  • 24
    • 4444364399 scopus 로고    scopus 로고
    • Bioinformatics for the 'bench biologist': How to find regulatory regions in genomic DNA
    • PMID:15282556
    • Nardone J, Lee DU, Ansel KM, Rao A. Bioinformatics for the 'bench biologist': how to find regulatory regions in genomic DNA. Nat Immunol 2004; 5:768-74; PMID:15282556; http://dx.doi.org/10.1038/ni0804-768.
    • (2004) Nat Immunol , vol.5 , pp. 768-774
    • Nardone, J.1    Lee, D.U.2    Ansel, K.M.3    Rao, A.4
  • 25
    • 0034507632 scopus 로고    scopus 로고
    • Transcription of eukaryotic protein-coding genes
    • PMID:11092823
    • Lee TI, Young RA. Transcription of eukaryotic protein-coding genes. Annu Rev Genet 2000; 34:77-137; PMID:11092823; http://dx.doi.org/10.1146/annurev. genet.34.1.77.
    • (2000) Annu Rev Genet , vol.34 , pp. 77-137
    • Lee, T.I.1    Young, R.A.2
  • 26
    • 40449110717 scopus 로고    scopus 로고
    • Differential contribution of NFATc2 and NFATc1 to TNFalpha gene expression in T cells
    • PMID:18097033
    • Kaminuma O, Kitamura F, Kitamura N, Hiroi T, Miyoshi H, Miyawaki A, et al. Differential contribution of NFATc2 and NFATc1 to TNFalpha gene expression in T cells. J Immunol 2008; 180:319-26; PMID:18097033.
    • (2008) J Immunol , vol.180 , pp. 319-326
    • Kaminuma, O.1    Kitamura, F.2    Kitamura, N.3    Hiroi, T.4    Miyoshi, H.5    Miyawaki, A.6
  • 27
    • 34548214756 scopus 로고    scopus 로고
    • The NFAT1 transcription factor is a repressor of cyclin A2 gene expression
    • PMID:17637565
    • Carvalho LD, Teixeira LK, Carrossini N, Caldeira AT, Ansel KM, Rao A, et al. The NFAT1 transcription factor is a repressor of cyclin A2 gene expression. Cell Cycle 2007; 6:1789-95; PMID:17637565; http:// dx.doi.org/10.4161/cc.6.14. 4473.
    • (2007) Cell Cycle , vol.6 , pp. 1789-1795
    • Carvalho, L.D.1    Teixeira, L.K.2    Carrossini, N.3    Caldeira, A.T.4    Ansel, K.M.5    Rao, A.6
  • 28
    • 0034663805 scopus 로고    scopus 로고
    • Integration of calcineurin and MEF2 signals by the coactivator p300 during T-cell apoptosis
    • PMID:10944115
    • Youn HD, Chatila TA, Liu JO. Integration of calcineurin and MEF2 signals by the coactivator p300 during T-cell apoptosis. EMBO J 2000; 19:4323-31; PMID:10944115; http://dx.doi.org/10.1093/ emboj/19.16.4323.
    • (2000) EMBO J , vol.19 , pp. 4323-4331
    • Youn, H.D.1    Chatila, T.A.2    Liu, J.O.3
  • 29
    • 0035859818 scopus 로고    scopus 로고
    • Cross talk among calcineurin, Sp1/Sp3 and NFAT in control of p21(WAF1/CIP1) expression in keratinocyte differentiation
    • PMID:11493684
    • Santini MP, Talora C, Seki T, Bolgan L, Dotto GP. Cross talk among calcineurin, Sp1/Sp3 and NFAT in control of p21(WAF1/CIP1) expression in keratinocyte differentiation. Proc Natl Acad Sci USA 2001; 98:9575-80; PMID:11493684; http://dx.doi. org/10.1073/pnas.161299698.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 9575-9580
    • Santini, M.P.1    Talora, C.2    Seki, T.3    Bolgan, L.4    Dotto, G.P.5
  • 30
    • 33646779199 scopus 로고    scopus 로고
    • The FUSE/FBP/FIR/TFIIH system is a molecular machine programming a pulse of c-myc expression
    • PMID:16628215
    • Liu J, Kouzine F, Nie Z, Chung HJ, Elisha-Feil Z, Weber A, et al. The FUSE/FBP/FIR/TFIIH system is a molecular machine programming a pulse of c-myc expression. EMBO J 2006; 25:2119-30; PMID:16628215; http://dx.doi.org/10.1038/ sj.emboj.7601101.
    • (2006) EMBO J , vol.25 , pp. 2119-2130
    • Liu, J.1    Kouzine, F.2    Nie, Z.3    Chung, H.J.4    Elisha-Feil, Z.5    Weber, A.6
  • 31
    • 33846977688 scopus 로고    scopus 로고
    • Distinct mammalian SWI/SNF chromatin remodeling complexes with opposing roles in cell cycle control
    • PMID:17255939
    • Nagl NG Jr, Wang X, Patsialou A, Van Scoy M, Moran E. Distinct mammalian SWI/SNF chromatin remodeling complexes with opposing roles in cell cycle control. EMBO J 2007; 26:752-63; PMID:17255939; http:// dx.doi.org/10.1038/sj. emboj.7601541.
    • (2007) EMBO J , vol.26 , pp. 752-763
    • Nagl Jr., N.G.1    Wang, X.2    Patsialou, A.3    Van Scoy, M.4    Moran, E.5
  • 32
    • 48849095875 scopus 로고    scopus 로고
    • NFAT is well placed to direct both enhancer looping and domain-wide models of enhancer function
    • PMID:18385038
    • Cockerill PN. NFAT is well placed to direct both enhancer looping and domain-wide models of enhancer function. Sci Signal 2008; 1:15; PMID:18385038; http://dx.doi.org/10.1126/stke.113pe15.
    • (2008) Sci Signal , vol.1 , pp. 15
    • Cockerill, P.N.1
  • 33
    • 0345218311 scopus 로고    scopus 로고
    • Nuclear factor of activated T cells (NFAT)-dependent transactivation regulated by the coactivators p300/CREB-binding protein (CBP)
    • PMID:9625762
    • García-Rodríguez C, Rao A. Nuclear factor of activated T cells (NFAT)-dependent transactivation regulated by the coactivators p300/CREB-binding protein (CBP). J Exp Med 1998; 187:2031-6; PMID:9625762; http:// dx.doi.org/10.1084/jem.187.12.2031.
    • (1998) J Exp Med , vol.187 , pp. 2031-2036
    • García-Rodríguez, C.1    Rao, A.2
  • 34
    • 3242658267 scopus 로고    scopus 로고
    • Human interleukin-5 expression is synergistically regulated by histone acetyltransferase CBP/p300 and transcription factors C/EBP, NF-AT and AP-1
    • PMID:15271374
    • Liu C, Lu J, Tan J, Li L, Huang B. Human interleukin-5 expression is synergistically regulated by histone acetyltransferase CBP/p300 and transcription factors C/EBP, NF-AT and AP-1. Cytokine 2004; 27:93-100; PMID:15271374; http://dx.doi.org/10.1016/j. cyto.2004.02.003.
    • (2004) Cytokine , vol.27 , pp. 93-100
    • Liu, C.1    Lu, J.2    Tan, J.3    Li, L.4    Huang, B.5
  • 35
    • 0034916613 scopus 로고    scopus 로고
    • p300/CBP proteins: HATs for transcriptional bridges and scaffolds
    • PMID:11559745
    • Chan HM, La Thangue NB. p300/CBP proteins: HATs for transcriptional bridges and scaffolds. J Cell Sci 2001; 114:2363-73; PMID:11559745.
    • (2001) J Cell Sci , vol.114 , pp. 2363-2373
    • Chan, H.M.1    La Thangue, N.B.2
  • 36
    • 0033137045 scopus 로고    scopus 로고
    • CBP/p300 integrates Raf/ Rac-signaling pathways in the transcriptional induction of NF-ATc during T cell activation
    • PMID:10367897
    • Avots A, Buttmann M, Chuvpilo S, Escher C, Smola U, Bannister AJ, et al. CBP/p300 integrates Raf/ Rac-signaling pathways in the transcriptional induction of NF-ATc during T cell activation. Immunity 1999; 10:515-24; PMID:10367897; http://dx.doi. org/10.1016/S1074-7613(00)80051-5.
    • (1999) Immunity , vol.10 , pp. 515-524
    • Avots, A.1    Buttmann, M.2    Chuvpilo, S.3    Escher, C.4    Smola, U.5    Bannister, A.J.6
  • 37
    • 52949140804 scopus 로고    scopus 로고
    • p300 provides a corepressor function by cooperating with YY1 and HDAC3 to repress c-Myc
    • PMID:18542060
    • Sankar N, Baluchamy S, Kadeppagari RK, Singhal G, Weitzman S, Thimmapaya B. p300 provides a corepressor function by cooperating with YY1 and HDAC3 to repress c-Myc. Oncogene 2008; 27:5717- 28; PMID:18542060; http://dx.doi.org/10. 1038/ onc.2008.181.
    • (2008) Oncogene , vol.27 , pp. 5717-5728
    • Sankar, N.1    Baluchamy, S.2    Kadeppagari, R.K.3    Singhal, G.4    Weitzman, S.5    Thimmapaya, B.6
  • 38
    • 0042924438 scopus 로고    scopus 로고
    • 1 exit in cells conditionally overexpressing p300 that is not dependent on its histone acetyltransferase activity
    • PMID:12883011
    • 1 exit in cells conditionally overexpressing p300 that is not dependent on its histone acetyltransferase activity. Proc Natl Acad Sci USA 2003; 100:9524-9; PMID:12883011; http://dx.doi.org/10.1073/ pnas.1633700100.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 9524-9529
    • Baluchamy, S.1    Rajabi, H.N.2    Thimmapaya, R.3    Navaraj, A.4    Thimmapaya, B.5
  • 39
    • 57349133026 scopus 로고    scopus 로고
    • Dual roles for NFAT transcription factor genes as oncogenes and tumor suppressors
    • PMID:18809576
    • Robbs BK, Cruz AL, Werneck MB, Mognol GP, Viola JP. Dual roles for NFAT transcription factor genes as oncogenes and tumor suppressors. Mol Cell Biol 2008; 28:7168-81; PMID:18809576; http://dx.doi. org/10.1128/MCB.00256-08.
    • (2008) Mol Cell Biol , vol.28 , pp. 7168-7181
    • Robbs, B.K.1    Cruz, A.L.2    Werneck, M.B.3    Mognol, G.P.4    Viola, J.P.5
  • 40
    • 0022719476 scopus 로고
    • A negative transcriptional control element located upstream of the murine c-myc gene
    • PMID:3013622
    • Remmers EF, Yang JQ, Marcu KB. A negative transcriptional control element located upstream of the murine c-myc gene. EMBO J 1986; 5:899-904; PMID:3013622.
    • (1986) EMBO J , vol.5 , pp. 899-904
    • Remmers, E.F.1    Yang, J.Q.2    Marcu, K.B.3
  • 41
    • 0036273063 scopus 로고    scopus 로고
    • What retroviruses teach us about the involvement of c-Myc in leukemias and lymphomas
    • PMID:12040439
    • Dudley JP, Mertz JA, Rajan L, Lozano M, Broussard DR. What retroviruses teach us about the involvement of c-Myc in leukemias and lymphomas. Leukemia 2002; 16:1086-98; PMID:12040439; http://dx.doi. org/10.1038/sj.leu.2402451.
    • (2002) Leukemia , vol.16 , pp. 1086-1098
    • Dudley, J.P.1    Mertz, J.A.2    Rajan, L.3    Lozano, M.4    Broussard, D.R.5
  • 42
    • 10644278704 scopus 로고    scopus 로고
    • Analysis of wild-type and mutant SL3-3 murine leukemia virus insertions in the c-myc promoter during lymphomagenesis reveals target site hot spots, virus-dependent patterns and frequent error-prone gap repair
    • PMID:15596802
    • Nielsen AA, Sørensen AB, Schmidt J, Pedersen FS. Analysis of wild-type and mutant SL3-3 murine leukemia virus insertions in the c-myc promoter during lymphomagenesis reveals target site hot spots, virus-dependent patterns and frequent error-prone gap repair. J Virol 2005; 79:67-78; PMID:15596802; http://dx.doi.org/10.1128/JVI.79.1.67-78.2005.
    • (2005) J Virol , vol.79 , pp. 67-78
    • Nielsen, A.A.1    Sørensen, A.B.2    Schmidt, J.3    Pedersen, F.S.4
  • 43
    • 0344197733 scopus 로고    scopus 로고
    • The c-myc insulator element and matrix attachment regions define the c-myc chromosomal domain
    • PMID:14645543
    • Gombert WM, Farris SD, Rubio ED, Morey-Rosler KM, Schubach WH, Krumm A. The c-myc insulator element and matrix attachment regions define the c-myc chromosomal domain. Mol Cell Biol 2003; 23:9338-48; PMID:14645543; http://dx.doi. org/10.1128/MCB.23.24.9338-48.2003.
    • (2003) Mol Cell Biol , vol.23 , pp. 9338-9348
    • Gombert, W.M.1    Farris, S.D.2    Rubio, E.D.3    Morey-Rosler, K.M.4    Schubach, W.H.5    Krumm, A.6
  • 44
    • 2942612219 scopus 로고    scopus 로고
    • p300/CBP and cancer
    • PMID:15156177
    • Iyer NG, Ozdag H, Caldas C. p300/CBP and cancer. Oncogene 2004; 23:4225-31; PMID:15156177; http://dx.doi.org/10.1038/sj.onc.1207118.
    • (2004) Oncogene , vol.23 , pp. 4225-4231
    • Iyer, N.G.1    Ozdag, H.2    Caldas, C.3
  • 45
    • 0030050784 scopus 로고    scopus 로고
    • Tumor necrosis factoralpha gene regulation in activated T cells involves ATF-2/Jun and NFATp
    • PMID:8552071
    • Tsai EY, Jain J, Pesavento PA, Rao A, Goldfeld AE. Tumor necrosis factoralpha gene regulation in activated T cells involves ATF-2/Jun and NFATp. Mol Cell Biol 1996; 16:459-67; PMID:8552071.
    • (1996) Mol Cell Biol , vol.16 , pp. 459-467
    • Tsai, E.Y.1    Jain, J.2    Pesavento, P.A.3    Rao, A.4    Goldfeld, A.E.5
  • 46
    • 0034604683 scopus 로고    scopus 로고
    • An essential role of the nuclear factor of activated T cells in the regulation of the expression of the cyclooxygenase-2 gene in human T lymphocytes
    • PMID:10816557
    • Iñiguez MA, Martinez-Martinez S, Punzón C, Redondo JM, Fresno M. An essential role of the nuclear factor of activated T cells in the regulation of the expression of the cyclooxygenase-2 gene in human T lymphocytes. J Biol Chem 2000; 275:23627-35; PMID:10816557; http://dx.doi.org/ 10.1074/jbc.M001381200.
    • (2000) J Biol Chem , vol.275 , pp. 23627-23635
    • Iñiguez, M.A.1    Martinez-Martinez, S.2    Punzón, C.3    Redondo, J.M.4    Fresno, M.5
  • 47
    • 15744397205 scopus 로고    scopus 로고
    • Expression and function of the nuclear factor of activated T cells in colon carcinoma cells: Involvement in the regulation of cyclooxygenase-2
    • PMID:15632146
    • Duque J, Fresno M, Iñiguez MA. Expression and function of the nuclear factor of activated T cells in colon carcinoma cells: involvement in the regulation of cyclooxygenase-2. J Biol Chem 2005; 280:8686- 93; PMID:15632146; http://dx.doi.org/10.1074/jbc. M413076200.
    • (2005) J Biol Chem , vol.280 , pp. 8686-8693
    • Duque, J.1    Fresno, M.2    Iñiguez, M.A.3
  • 48
    • 0029929793 scopus 로고    scopus 로고
    • An exceptionally conserved transcriptional repressor, CTCF, employs different combinations of zinc fingers to bind diverged promoter sequences of avian and mammalian c-myc oncogenes
    • PMID:8649389
    • Filippova GN, Fagerlie S, Klenova EM, Myers C, Dehner Y, Goodwin G, et al. An exceptionally conserved transcriptional repressor, CTCF, employs different combinations of zinc fingers to bind diverged promoter sequences of avian and mammalian c-myc oncogenes. Mol Cell Biol 1996; 16:2802-13; PMID:8649389.
    • (1996) Mol Cell Biol , vol.16 , pp. 2802-2813
    • Filippova, G.N.1    Fagerlie, S.2    Klenova, E.M.3    Myers, C.4    Dehner, Y.5    Goodwin, G.6
  • 49
    • 0035827560 scopus 로고    scopus 로고
    • The chromatin structure of the dual c-myc promoter P1/P2 is regulated by separate elements
    • PMID:11279041
    • Albert T, Wells J, Funk JO, Pullner A, Raschke EE, Stelzer G, et al. The chromatin structure of the dual c-myc promoter P1/P2 is regulated by separate elements. J Biol Chem 2001; 276:20482-90; PMID:11279041; http://dx.doi.org/10. 1074/jbc. M100265200.
    • (2001) J Biol Chem , vol.276 , pp. 20482-20490
    • Albert, T.1    Wells, J.2    Funk, J.O.3    Pullner, A.4    Raschke, E.E.5    Stelzer, G.6
  • 50
    • 0024525025 scopus 로고
    • DNA topology of the ordered chromatin domain 5′ to the human c-myc gene
    • PMID:2717410
    • Kumar S, Leffak M. DNA topology of the ordered chromatin domain 5′ to the human c-myc gene. Nucleic Acids Res 1989; 17:2819-33; PMID:2717410; http://dx.doi.org/10.1093/nar/17.7.2819.
    • (1989) Nucleic Acids Res , vol.17 , pp. 2819-2833
    • Kumar, S.1    Leffak, M.2
  • 51
    • 33748199553 scopus 로고    scopus 로고
    • Conditional transgenic models define how MYC initiates and maintains tumorigenesis
    • PMID:16935001
    • Arvanitis C, Felsher DW. Conditional transgenic models define how MYC initiates and maintains tumorigenesis. Semin Cancer Biol 2006; 16:313-7; PMID:16935001; http://dx.doi.org/10.1016/j.semcancer. 2006.07.012.
    • (2006) Semin Cancer Biol , vol.16 , pp. 313-317
    • Arvanitis, C.1    Felsher, D.W.2
  • 52
    • 34548771087 scopus 로고    scopus 로고
    • Cellular senescence is an important mechanism of tumor regression upon c-Myc inactivation
    • PMID:17664422
    • Wu CH, van Riggelen J, Yetil A, Fan AC, Bachireddy P, Felsher DW. Cellular senescence is an important mechanism of tumor regression upon c-Myc inactivation. Proc Natl Acad Sci USA 2007; 104:13028- 33; PMID:17664422; http://dx.doi.org/10.1073/ pnas.0701953104.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 13028-13033
    • Wu, C.H.1    Van Riggelen, J.2    Yetil, A.3    Fan, A.C.4    Bachireddy, P.5    Felsher, D.W.6
  • 53
    • 13444270409 scopus 로고    scopus 로고
    • The NFATc1 transcription factor is widely expressed in white cells and translocates from the cytoplasm to the nucleus in a subset of human lymphomas
    • PMID:15667535
    • Marafioti T, Pozzobon M, Hansmann ML, Ventura R, Pileri SA, Roberton H, et al. The NFATc1 transcription factor is widely expressed in white cells and translocates from the cytoplasm to the nucleus in a subset of human lymphomas. Br J Haematol 2005; 128:333-42; PMID:15667535; http://dx.doi.org/10.1111/j.1365- 2141.2004.05313.x.
    • (2005) Br J Haematol , vol.128 , pp. 333-342
    • Marafioti, T.1    Pozzobon, M.2    Hansmann, M.L.3    Ventura, R.4    Pileri, S.A.5    Roberton, H.6
  • 54
    • 40549104452 scopus 로고    scopus 로고
    • The calcineurin/NFAT signaling pathway: A novel therapeutic target in leukemia and solid tumors
    • PMID:18235236
    • Medyouf H, Ghysdael J. The calcineurin/NFAT signaling pathway: a novel therapeutic target in leukemia and solid tumors. Cell Cycle 2008; 7:297- 303; PMID:18235236; http://dx.doi.org/10.4161/ cc.7.3.5357.
    • (2008) Cell Cycle , vol.7 , pp. 297-303
    • Medyouf, H.1    Ghysdael, J.2
  • 55
    • 27944446105 scopus 로고    scopus 로고
    • Akt blocks breast cancer cell motility and invasion through the transcription factor NFAT
    • PMID:16307918
    • Yoeli-Lerner M, Yiu GK, Rabinovitz I, Erhardt P, Jauliac S, Toker A. Akt blocks breast cancer cell motility and invasion through the transcription factor NFAT. Mol Cell 2005; 20:539-50; PMID:16307918; http:// dx.doi.org/10.1016/j. molcel.2005.10.033.
    • (2005) Mol Cell , vol.20 , pp. 539-550
    • Yoeli-Lerner, M.1    Yiu, G.K.2    Rabinovitz, I.3    Erhardt, P.4    Jauliac, S.5    Toker, A.6
  • 56
    • 33744948986 scopus 로고    scopus 로고
    • NFAT induces breast cancer cell invasion by promoting the induction of cyclooxygenase-2
    • PMID:16505480
    • Yiu GK, Toker A. NFAT induces breast cancer cell invasion by promoting the induction of cyclooxygenase-2. J Biol Chem 2006; 281:12210-7; PMID:16505480; http://dx.doi.org/10.1074/jbc.M600184200.
    • (2006) J Biol Chem , vol.281 , pp. 12210-12217
    • Yiu, G.K.1    Toker, A.2
  • 57
    • 33746990262 scopus 로고    scopus 로고
    • 2+-induced NFAT activity is counteracted by Wnt-5a/Yes-Cdc42-casein kinase 1alpha signaling in human mammary epithelial cells
    • PMID:16880514
    • 2+-induced NFAT activity is counteracted by Wnt-5a/Yes-Cdc42-casein kinase 1alpha signaling in human mammary epithelial cells. Mol Cell Biol 2006; 26:6024-36; PMID:16880514; http://dx.doi.org/10.1128/ MCB.02354-05.
    • (2006) Mol Cell Biol , vol.26 , pp. 6024-6036
    • Dejmek, J.1    Säfholm, A.2    Kamp Nielsen, C.3    Andersson, T.4    Leandersson, K.5
  • 58
    • 33846215529 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha is a potent endogenous mutagen that promotes cellular transformation
    • PMID:17178846
    • Yan B, Wang H, Rabbani ZN, Zhao Y, Li W, Yuan Y, et al. Tumor necrosis factor-alpha is a potent endogenous mutagen that promotes cellular transformation. Cancer Res 2006; 66:11565-70; PMID:17178846; http:// dx.doi.org/10.1158/0008-5472.CAN-06-2540.
    • (2006) Cancer Res , vol.66 , pp. 11565-11570
    • Yan, B.1    Wang, H.2    Rabbani, Z.N.3    Zhao, Y.4    Li, W.5    Yuan, Y.6
  • 59
    • 4644244293 scopus 로고    scopus 로고
    • Transcriptional activation of c-myc proto-oncogene by WT1 protein
    • PMID:15286719
    • Han Y, San-Marina S, Liu J, Minden MD. Transcriptional activation of c-myc proto-oncogene by WT1 protein. Oncogene 2004; 23:6933- 41; PMID:15286719; http://dx.doi.org/10.1038/ sj.onc.1207609.
    • (2004) Oncogene , vol.23 , pp. 6933-6941
    • Han, Y.1    San-Marina, S.2    Liu, J.3    Minden, M.D.4
  • 60
    • 68249162061 scopus 로고    scopus 로고
    • Integrin alpha6Bbeta4 inhibits colon cancer cell proliferation and c-Myc activity
    • PMID:19586553
    • Dydensborg AB, Teller IC, Groulx JF, Basora N, Paré F, Herring E, et al. Integrin alpha6Bbeta4 inhibits colon cancer cell proliferation and c-Myc activity. BMC Cancer 2009; 9:223; PMID:19586553; http://dx.doi. org/10.1186/1471-2407-9-223.
    • (2009) BMC Cancer , vol.9 , pp. 223
    • Dydensborg, A.B.1    Teller, I.C.2    Groulx, J.F.3    Basora, N.4    Paré, F.5    Herring, E.6
  • 61
    • 0029882657 scopus 로고    scopus 로고
    • An enhanced immune response in mice lacking the transcription factor NFAT1
    • PMID:8629027
    • Xanthoudakis S, Viola JP, Shaw KT, Luo C, Wallace JD, Bozza PT, et al. An enhanced immune response in mice lacking the transcription factor NFAT1. Science 1996; 272:892-5; PMID:8629027; http://dx.doi. org/10.1126/science.272. 5263.892.
    • (1996) Science , vol.272 , pp. 892-895
    • Xanthoudakis, S.1    Viola, J.P.2    Shaw, K.T.3    Luo, C.4    Wallace, J.D.5    Bozza, P.T.6
  • 62
    • 0032483439 scopus 로고    scopus 로고
    • Identification of c-MYC as a target of the APC pathway
    • PMID:9727977
    • He TC, Sparks AB, Rago C, Hermeking H, Zawel L, da Costa LT, et al. Identification of c-MYC as a target of the APC pathway. Science 1998; 281:1509-12; PMID:9727977; http://dx.doi.org/10.1126/science. 281.5382.1509.
    • (1998) Science , vol.281 , pp. 1509-1512
    • He, T.C.1    Sparks, A.B.2    Rago, C.3    Hermeking, H.4    Zawel, L.5    Da Costa, L.T.6
  • 63
    • 0035970035 scopus 로고    scopus 로고
    • Defective repression of c-myc in breast cancer cells: A loss at the core of the transforming growth factor beta growth arrest program
    • PMID:11158583
    • Chen CR, Kang Y, Massagué J. Defective repression of c-myc in breast cancer cells: A loss at the core of the transforming growth factor beta growth arrest program. Proc Natl Acad Sci USA 2001; 98:992-9; PMID:11158583; http://dx.doi.org/10.1073/ pnas.98.3.992.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 992-999
    • Chen, C.R.1    Kang, Y.2    Massagué, J.3
  • 65
    • 0028938658 scopus 로고
    • A similar DNA binding motif in NFAT family proteins and the Rel homology region
    • PMID:7876165
    • Jain J, Burgeon E, Badalian TM, Hogan PG, Rao A. A similar DNA binding motif in NFAT family proteins and the Rel homology region. J Biol Chem 1995; 270:4138-45; PMID:7876165; http://dx.doi. org/10.1074/jbc.270.8.4138.
    • (1995) J Biol Chem , vol.270 , pp. 4138-4145
    • Jain, J.1    Burgeon, E.2    Badalian, T.M.3    Hogan, P.G.4    Rao, A.5
  • 66
    • 0026596383 scopus 로고
    • Nuclear factor of activated T cells contains Fos and Jun
    • PMID:1533441
    • Jain J, McCaffrey PG, Valge-Archer VE, Rao A. Nuclear factor of activated T cells contains Fos and Jun. Nature 1992; 356:801-4; PMID:1533441; http:// dx.doi.org/10.1038/356801a0.
    • (1992) Nature , vol.356 , pp. 801-804
    • Jain, J.1    McCaffrey, P.G.2    Valge-Archer, V.E.3    Rao, A.4


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