Coronary vasospasm induced in transgenic mouse with increased phospholipase C-δ1 activity

Circulation

Volumn 125, Issue 8, 2012, Pages 1027-1036

  Shibutani, Shuji ^a   Osanai, Tomohiro ^a   Ashitate, Toshihiro ^a   Sagara, Shigeki ^a   Izumiyama, Kei ^a   Yamamoto, Yuko ^a   Hanada, Kenji ^a   Echizen, Takashi ^a   Tomita, Hirofumi ^a   Fujita, Takeshi ^a   Miwa, Takeshi ^b   Matsubara, Hiroaki ^c   Homma, Yoshimi ^d   Okumura, Ken ^a  

^a HIROSAKI UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^d FUKUSHIMA MEDICAL UNIVERSITY   (Japan)

Author keywords

calcium; genetics; smooth muscle; vasospasm

Indexed keywords

ACETYLCHOLINE; ARGININE; CALCIUM ION; ERGOMETRINE; HISTIDINE; PHOSPHOLIPASE C DELTA1; PROSTAGLANDIN F2 ALPHA;

AMINO ACID SUBSTITUTION; ANGINA PECTORIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRADYCARDIA; CALCIUM CELL LEVEL; CARDIOVASCULAR PARAMETERS; COMPLETE HEART BLOCK; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; CORONARY ARTERY OBSTRUCTION; CORONARY ARTERY PRESSURE; CORONARY ARTERY SPASM; ECHOCARDIOGRAPHY; ELECTROCARDIOGRAM; ENZYME ACTIVITY; GENE EXPRESSION; GENETIC TRANSFECTION; HETEROZYGOTE; HOMOZYGOTE; IMMUNOFLUORESCENCE MICROSCOPY; ISOLATED HEART; MICROVASCULATURE; MOUSE; NONHUMAN; PERFUSION PRESSURE; PHENOTYPE; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE FIBER; ST SEGMENT ELEVATION; TRANSGENIC MOUSE; VASCULAR SMOOTH MUSCLE; WILD TYPE;

ANIMALS; CELLS, CULTURED; CORONARY CIRCULATION; CORONARY VASOSPASM; ENZYME INDUCTION; GENETIC VARIATION; HUMANS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PHOSPHOLIPASE C DELTA; RATS; UP-REGULATION;

EID: 84857954952     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.111.064303     Document Type: Article

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