Inactivation of phosphomannose isomerase gene abolishes sporulation and antibiotic production in Streptomyces coelicolor

Applied Microbiology and Biotechnology

Volumn 93, Issue 4, 2012, Pages 1685-1693

  Rajesh, Thangamani ^a   Song, Eunjung ^b   Kim, Ji Nu ^b   Lee, Bo Rahm ^b   Kim, Eun Jung ^b   Park, Sung Hee ^b   Kim, Yun Gon ^b   Yoo, Dongwon ^b   Park, Hyung Yeon ^b   Choi, Yun Hui ^b   Kim, Byung Gee ^b   Yang, Yung Hun ^a  

^a Konkuk University   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

Antibiotic production; Complementation analysis; Phosphomannose isomerase; Pigment production; Sporulation

Indexed keywords

ANTIBIOTIC PRODUCTION; COMPLEMENTATION; PHOSPHO-MANNOSE ISOMERASE; PIGMENT PRODUCTION; SPORULATION;

BACTERIA; BIOCHEMISTRY; CARBOHYDRATES; CLONING; ENCODING (SYMBOLS); ENZYMES; ESCHERICHIA COLI; GENES; PURIFICATION;

ANTIBIOTICS;

ACTINORHODINE; ANTIBIOTIC AGENT; GUANOSINE DIPHOSPHATE DEXTRO MANNOSE PYROPHOSPHORYLASE; MANNOSE PHOSPHATE ISOMERASE; PHOSPHORYLASE; RED TRIPYROLLE UNDECYLPRODIGIOSIN; UNCLASSIFIED DRUG;

ANTIBIOTICS; BACTERIUM; ENZYME ACTIVITY; KINETICS; METABOLITE; PHENOTYPE; PIGMENT; PROTEIN; RECOMBINATION; SPORULATION;

AMINO ACID SEQUENCE; ARTICLE; CARBOHYDRATE METABOLISM; CELL DIFFERENTIATION; DRUG MANUFACTURE; ENZYME ACTIVITY; ENZYME KINETICS; ESCHERICHIA COLI; GENE EXPRESSION; GENE FUNCTION; GENE INACTIVATION; MOLECULAR CLONING; NONHUMAN; PHENOTYPE; SPOROGENESIS; STREPTOMYCES COELICOLOR;

ANTHRAQUINONES; ANTI-BACTERIAL AGENTS; CLONING, MOLECULAR; ESCHERICHIA COLI; GENE DELETION; GENE EXPRESSION; GENETIC COMPLEMENTATION TEST; KINETICS; MANNOSE-6-PHOSPHATE ISOMERASE; MUTAGENESIS, INSERTIONAL; PRODIGIOSIN; RECOMBINANT PROTEINS; SPORES, BACTERIAL; STREPTOMYCES COELICOLOR;

ESCHERICHIA COLI; FUNGI; STREPTOMYCES COELICOLOR;

EID: 84857922835     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-011-3581-z     Document Type: Article

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