메뉴 건너뛰기




Volumn 76, Issue 23, 2010, Pages 7741-7753

Repression of antibiotic production and sporulation in Streptomyces coelicolor by overexpression of a TetR family transcriptional regulator

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTICS; BACTERIA; TRANSCRIPTION;

EID: 78650385274     PISSN: 00992240     EISSN: 10985336     Source Type: Journal    
DOI: 10.1128/AEM.00819-10     Document Type: Article
Times cited : (34)

References (72)
  • 1
    • 0031800852 scopus 로고    scopus 로고
    • Transcriptional regulation of Streptomyces coelicolor pathway-specific antibiotic regulators by the absA and absB loci
    • Aceti, D. J., and W. C. Champness. 1998. Transcriptional regulation of Streptomyces coelicolor pathway-specific antibiotic regulators by the absA and absB loci. J. Bacteriol. 180:3100-3106.
    • (1998) J. Bacteriol. , vol.180 , pp. 3100-3106
    • Aceti, D.J.1    Champness, W.C.2
  • 2
    • 0028685490 scopus 로고
    • Fitting a mixture model by expectation maximization to discover motifs in biopolymers
    • Bailey, T. L., and C. Elkan. 1994. Fitting a mixture model by expectation maximization to discover motifs in biopolymers. Proc. Int. Conf. Intell. Syst. Mol. Biol. 2:28-36.
    • (1994) Proc. Int. Conf. Intell. Syst. Mol. Biol. , vol.2 , pp. 28-36
    • Bailey, T.L.1    Elkan, C.2
  • 3
    • 0034212551 scopus 로고    scopus 로고
    • Engineering stability in gene networks by autoregulation
    • Becskei, A., and L. Serrano. 2000. Engineering stability in gene networks by autoregulation. Nature 405:590-593.
    • (2000) Nature , vol.405 , pp. 590-593
    • Becskei, A.1    Serrano, L.2
  • 4
    • 0029945534 scopus 로고    scopus 로고
    • The regulation of antibiotic production in Streptomyces coelicolor A3(2)
    • 1995 Colworth Prize Lecture
    • Bibb, M. 1996. 1995 Colworth Prize Lecture. The regulation of antibiotic production in Streptomyces coelicolor A3(2). Microbiology 142(Part 6):1335-1344.
    • (1996) Microbiology , vol.142 , Issue.PART 6 , pp. 1335-1344
    • Bibb, M.1
  • 5
    • 0022404392 scopus 로고
    • Cloning and analysis of the promoter region of the erythromycin resistance gene (ermE) of Streptomyces erythraeus
    • Bibb, M. J., G. R. Janssen, and J. M. Ward. 1985. Cloning and analysis of the promoter region of the erythromycin resistance gene (ermE) of Streptomyces erythraeus. Gene 38:215-226.
    • (1985) Gene , vol.38 , pp. 215-226
    • Bibb, M.J.1    Janssen, G.R.2    Ward, J.M.3
  • 6
    • 0031006412 scopus 로고    scopus 로고
    • Antibiotic resistance gene cassettes derived from the omega interposon for use in E. coli and Streptomyces
    • Blondelet-Rouault, M. H., J. Weiser, A. Lebrihi, P. Branny, and J. L. Pernodet. 1997. Antibiotic resistance gene cassettes derived from the omega interposon for use in E. coli and Streptomyces. Gene 190:315-317.
    • (1997) Gene , vol.190 , pp. 315-317
    • Blondelet-Rouault, M.H.1    Weiser, J.2    Lebrihi, A.3    Branny, P.4    Pernodet, J.L.5
  • 7
    • 0036126629 scopus 로고    scopus 로고
    • High-yield actinorhodin production in fed-batch culture by a Streptomyces lividans strain overexpressing the pathway-specific activator gene actll-ORF4
    • Bruheim, P., H. Sletta, M. J. Bibb, J. White, and D. W. Levine. 2002. High-yield actinorhodin production in fed-batch culture by a Streptomyces lividans strain overexpressing the pathway-specific activator gene actll-ORF4. J. Ind. Microbiol. Biotechnol. 28:103-111.
    • (2002) J. Ind. Microbiol. Biotechnol. , vol.28 , pp. 103-111
    • Bruheim, P.1    Sletta, H.2    Bibb, M.J.3    White, J.4    Levine, D.W.5
  • 8
    • 0345492332 scopus 로고    scopus 로고
    • Synergy and contingency as driving forces for the evolution of multiple secondary metabolite production by Streptomyces species
    • Challis, G. L., and D. A. Hopwood. 2003. Synergy and contingency as driving forces for the evolution of multiple secondary metabolite production by Streptomyces species. Proc. Natl. Acad. Sci. U. S. A. 100(Suppl. 2):14555-14561.
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , Issue.SUPPL. 2 , pp. 14555-14561
    • Challis, G.L.1    Hopwood, D.A.2
  • 9
    • 0029821306 scopus 로고    scopus 로고
    • The cutRS signal transduction system of Streptomyces lividans represses the biosynthesis of the polyketide antibiotic actinorhodin
    • Chang, H. M., M. Y. Chen, Y. T. Shieh, M. J. Bibb, and C. W. Chen. 1996. The cutRS signal transduction system of Streptomyces lividans represses the biosynthesis of the polyketide antibiotic actinorhodin. Mol. Microbiol. 21: 1075-1085.
    • (1996) Mol. Microbiol. , vol.21 , pp. 1075-1085
    • Chang, H.M.1    Chen, M.Y.2    Shieh, Y.T.3    Bibb, M.J.4    Chen, C.W.5
  • 10
    • 0027384770 scopus 로고
    • Genetics of differentiation in Streptomyces
    • Chater, K. F. 1993. Genetics of differentiation in Streptomyces. Annu. Rev. Microbiol. 47:685-713.
    • (1993) Annu. Rev. Microbiol. , vol.47 , pp. 685-713
    • Chater, K.F.1
  • 11
    • 0036231769 scopus 로고    scopus 로고
    • The polyphosphate kinase plays a negative role in the control of antibiotic production in Streptomyces lividans
    • Chouayekh, H., and M. J. Virolle. 2002. The polyphosphate kinase plays a negative role in the control of antibiotic production in Streptomyces lividans. Mol. Microbiol. 43:919-930.
    • (2002) Mol. Microbiol. , vol.43 , pp. 919-930
    • Chouayekh, H.1    Virolle, M.J.2
  • 12
    • 0141995011 scopus 로고    scopus 로고
    • The iron-responsive regulator fur is transcriptionally autoregulated and not essential in Neisseria meningitidis
    • Delany, I., R. Ieva, C. Alaimo, R. Rappuoli, and V. Scarlato. 2003. The iron-responsive regulator fur is transcriptionally autoregulated and not essential in Neisseria meningitidis. J. Bacteriol. 185:6032-6041.
    • (2003) J. Bacteriol. , vol.185 , pp. 6032-6041
    • Delany, I.1    Ieva, R.2    Alaimo, C.3    Rappuoli, R.4    Scarlato, V.5
  • 13
    • 0022357903 scopus 로고
    • Genetic and biochemical characterization of the red gene cluster of Streptomyces coelicolor A3(2)
    • Feitelson, J. S., F. Malpartida, and D. A. Hopwood. 1985. Genetic and biochemical characterization of the red gene cluster of Streptomyces coelicolor A3(2). J. Gen. Microbiol. 131:2431-2441.
    • (1985) J. Gen. Microbiol. , vol.131 , pp. 2431-2441
    • Feitelson, J.S.1    Malpartida, F.2    Hopwood, D.A.3
  • 14
    • 0025899144 scopus 로고
    • The act cluster contains regulatory and antibiotic export genes, direct targets for translational control by the bldA tRNA gene of Streptomyces
    • Fernandez-Moreno, M. A., J. L. Caballero, D. A. Hopwood, and F. Malpar-tida. 1991. The act cluster contains regulatory and antibiotic export genes, direct targets for translational control by the bldA tRNA gene of Streptomyces. Cell 66:769-780.
    • (1991) Cell , vol.66 , pp. 769-780
    • Fernandez-Moreno, M.A.1    Caballero, J.L.2    Hopwood, D.A.3    Malpar-Tida, F.4
  • 15
    • 55549086417 scopus 로고    scopus 로고
    • Streptomyces morphogenetics: Dissecting differentiation in a filamentous bacterium
    • Flardh, K., and M. J. Buttner. 2009. Streptomyces morphogenetics: Dissecting differentiation in a filamentous bacterium. Nat. Rev. Microbiol. 7:36-49.
    • (2009) Nat. Rev. Microbiol. , vol.7 , pp. 36-49
    • Flardh, K.1    Buttner, M.J.2
  • 16
    • 30744468390 scopus 로고    scopus 로고
    • Transcriptional studies and regulatory interactions between the phoR-phoP operon and the phoU, mtpA, and ppk genes of Streptomyces lividans TK24
    • Ghorbel, S., J. Kormanec, A. Artus, and M. J. Virolle. 2006. Transcriptional studies and regulatory interactions between the phoR-phoP operon and the phoU, mtpA, and ppk genes of Streptomyces lividans TK24. J. Bacteriol. 188:677-686.
    • (2006) J. Bacteriol. , vol.188 , pp. 677-686
    • Ghorbel, S.1    Kormanec, J.2    Artus, A.3    Virolle, M.J.4
  • 17
    • 77955343496 scopus 로고    scopus 로고
    • Deletion of a regulatory gene within the cpk gene cluster reveals novel antibacterial activity in Streptomyces coelicolor A3(2)
    • Gottelt, M., S. Kol, J. P. Gomez-Escribano, M. Bibb, and E. Takano. 2010. Deletion of a regulatory gene within the cpk gene cluster reveals novel antibacterial activity in Streptomyces coelicolor A3(2). Microbiology 156:2343-2353.
    • (2010) Microbiology , vol.156 , pp. 2343-2353
    • Gottelt, M.1    Kol, S.2    Gomez-Escribano, J.P.3    Bibb, M.4    Takano, E.5
  • 18
    • 0027483415 scopus 로고
    • Stationary-phase production of the antibiotic actinorhodin in Streptomyces coelicolor A3(2) is transcriptionally regulated
    • Gramajo, H. C., E. Takano, and M. J. Bibb. 1993. Stationary-phase production of the antibiotic actinorhodin in Streptomyces coelicolor A3(2) is transcriptionally regulated. Mol. Microbiol. 7:837-845.
    • (1993) Mol. Microbiol. , vol.7 , pp. 837-845
    • Gramajo, H.C.1    Takano, E.2    Bibb, M.J.3
  • 19
    • 0031906193 scopus 로고    scopus 로고
    • A response-regulator-like activator of antibiotic synthesis from Streptomyces coelicolor A3(2) with an amino-terminal domain that lacks a phosphorylation pocket
    • Guthrie, E. P., C. S. Flaxman, J. White, D. A. Hodgson, M. J. Bibb, and K. F. Chater. 1998. A response-regulator-like activator of antibiotic synthesis from Streptomyces coelicolor A3(2) with an amino-terminal domain that lacks a phosphorylation pocket. Microbiology 144:727-738.
    • (1998) Microbiology , vol.144 , pp. 727-738
    • Guthrie, E.P.1    Flaxman, C.S.2    White, J.3    Hodgson, D.A.4    Bibb, M.J.5    Chater, K.F.6
  • 22
    • 0036778196 scopus 로고    scopus 로고
    • A microbial hormone, A-factor, as a master switch for morphological differentiation and secondary metabolism in Streptomyces griseus
    • Horinouchi, S. 2002. A microbial hormone, A-factor, as a master switch for morphological differentiation and secondary metabolism in Streptomyces griseus. Front. Biosci. 7:d2045-d2057.
    • (2002) Front. Biosci. , vol.7
    • Horinouchi, S.1
  • 23
    • 33746543095 scopus 로고    scopus 로고
    • Increased expression of ribosome recycling factor is responsible for the enhanced protein synthesis during the late growth phase in an antibiotic-overproducing Streptomyces coelicolor ribosomal rpsL mutant
    • Hosaka, T., J. Xu, and K. Ochi. 2006. Increased expression of ribosome recycling factor is responsible for the enhanced protein synthesis during the late growth phase in an antibiotic-overproducing Streptomyces coelicolor ribosomal rpsL mutant. Mol. Microbiol. 61:883-897.
    • (2006) Mol. Microbiol. , vol.61 , pp. 883-897
    • Hosaka, T.1    Xu, J.2    Ochi, K.3
  • 24
    • 33745906951 scopus 로고    scopus 로고
    • DevA, a GntR-like transcriptional regulator required for development in Streptomyces coelicolor
    • Hoskisson, P. A., S. Rigali, K. Fowler, K. C. Findlay, and M. J. Buttner. 2006. DevA, a GntR-like transcriptional regulator required for development in Streptomyces coelicolor. J. Bacteriol. 188:5014-5023.
    • (2006) J. Bacteriol. , vol.188 , pp. 5014-5023
    • Hoskisson, P.A.1    Rigali, S.2    Fowler, K.3    Findlay, K.C.4    Buttner, M.J.5
  • 25
    • 0036299643 scopus 로고    scopus 로고
    • Activation of antibiotic biosynthesis by specified mutations in the rpoB gene (encoding the RNA polymerase beta subunit) of Streptomyces lividans
    • Hu, H., Q. Zhang, and K. Ochi. 2002. Activation of antibiotic biosynthesis by specified mutations in the rpoB gene (encoding the RNA polymerase beta subunit) of Streptomyces lividans. J. Bacteriol. 184:3984-3991.
    • (2002) J. Bacteriol. , vol.184 , pp. 3984-3991
    • Hu, H.1    Zhang, Q.2    Ochi, K.3
  • 26
    • 0001936118 scopus 로고
    • Gene cloning in Streptomyces
    • In D. M. Glover (ed.). IRL Press, Washington, DC
    • Hunter, I. S. 1985. Gene cloning in Streptomyces, p. 19-44. In D. M. Glover (ed.), DNA cloning: A practical approach. IRL Press, Washington, DC.
    • (1985) DNA Cloning: A Practical Approach , pp. 19-44
    • Hunter, I.S.1
  • 27
    • 4844230017 scopus 로고    scopus 로고
    • Sensing and responding to diverse extracellular signals? Analysis of the sensor kinases and response regulators of Streptomyces coelicolor A3(2)
    • Hutchings, M. I., P. A. Hoskisson, G. Chandra, and M. J. Buttner. 2004. Sensing and responding to diverse extracellular signals? Analysis of the sensor kinases and response regulators of Streptomyces coelicolor A3(2). Microbiology 150:2795-2806.
    • (2004) Microbiology , vol.150 , pp. 2795-2806
    • Hutchings, M.I.1    Hoskisson, P.A.2    Chandra, G.3    Buttner, M.J.4
  • 28
    • 0024377190 scopus 로고
    • XylE functions as an efficient reporter gene in Streptomyces spp.: Use for the study of galP1, a catabolite-controlled promoter
    • Ingram, C., M. Brawner, P. Youngman, and J. Westpheling. 1989. xylE functions as an efficient reporter gene in Streptomyces spp.: use for the study of galP1, a catabolite-controlled promoter. J. Bacteriol. 171:6617-6624.
    • (1989) J. Bacteriol. , vol.171 , pp. 6617-6624
    • Ingram, C.1    Brawner, M.2    Youngman, P.3    Westpheling, J.4
  • 29
    • 0001420957 scopus 로고
    • Involvement of a small ORF downstream of the afsR gene in the regulation of secondary metabolism in Streptomyces coelicolor A3(2)
    • Ishizuka, H., T. Beppu, and S. Horinouchi. 1995. Involvement of a small ORF downstream of the afsR gene in the regulation of secondary metabolism in Streptomyces coelicolor A3(2). Actinomycetologica 9:37-43.
    • (1995) Actinomycetologica , vol.9 , pp. 37-43
    • Ishizuka, H.1    Beppu, T.2    Horinouchi, S.3
  • 30
    • 34548042564 scopus 로고    scopus 로고
    • Comparative genomic hybridizations reveal absence of large Streptomyces coelicolor genomic islands in Streptomyces lividans
    • Jayapal, K. P., W. Lian, F. Glod, D. H. Sherman, and W. S. Hu. 2007. Comparative genomic hybridizations reveal absence of large Streptomyces coelicolor genomic islands in Streptomyces lividans. BMC Genomics 8:229.
    • (2007) BMC Genomics , vol.8 , pp. 229
    • Jayapal, K.P.1    Lian, W.2    Glod, F.3    Sherman, D.H.4    Hu, W.S.5
  • 31
    • 20444379644 scopus 로고    scopus 로고
    • Autorepression of AdpA of the AraC/XylS family, a key transcriptional activator in the A-factor regulatory cascade in Streptomyces griseus
    • Kato, J. Y., Y. Ohnishi, and S. Horinouchi. 2005. Autorepression of AdpA of the AraC/XylS family, a key transcriptional activator in the A-factor regulatory cascade in Streptomyces griseus. J. Mol. Biol. 350:12-26.
    • (2005) J. Mol. Biol. , vol.350 , pp. 12-26
    • Kato, J.Y.1    Ohnishi, Y.2    Horinouchi, S.3
  • 32
    • 0020564356 scopus 로고
    • Cloning and expression of the tyrosinase gene from Streptomyces antibioticus in Streptomyces lividans
    • Katz, E., C. J. Thompson, and D. A. Hopwood. 1983. Cloning and expression of the tyrosinase gene from Streptomyces antibioticus in Streptomyces lividans. J. Gen. Microbiol. 129:2703-2714.
    • (1983) J. Gen. Microbiol. , vol.129 , pp. 2703-2714
    • Katz, E.1    Thompson, C.J.2    Hopwood, D.A.3
  • 34
    • 0037224691 scopus 로고    scopus 로고
    • Accumulation of S-adenosyl-L-methionine enhances production of actinorhodin but inhibits sporulation in Streptomyces lividans TK23
    • Kim, D. J., J. H. Huh, Y. Y. Yang, C. M. Kang, I. H. Lee, C. G. Hyun, S. K. Hong, and J. W. Suh. 2003. Accumulation of S-adenosyl-L-methionine enhances production of actinorhodin but inhibits sporulation in Streptomyces lividans TK23. J. Bacteriol. 185:592-600.
    • (2003) J. Bacteriol. , vol.185 , pp. 592-600
    • Kim, D.J.1    Huh, J.H.2    Yang, Y.Y.3    Kang, C.M.4    Lee, I.H.5    Hyun, C.G.6    Hong, S.K.7    Suh, J.W.8
  • 35
    • 0035087341 scopus 로고    scopus 로고
    • Modulation of actinorhodin biosynthesis in Streptomyces lividans by glucose repression of afsR2 gene transcription
    • Kim, E. S., H. J. Hong, C. Y. Choi, and S. N. Cohen. 2001. Modulation of actinorhodin biosynthesis in Streptomyces lividans by glucose repression of afsR2 gene transcription. J. Bacteriol. 183:2198-2203.
    • (2001) J. Bacteriol. , vol.183 , pp. 2198-2203
    • Kim, E.S.1    Hong, H.J.2    Choi, C.Y.3    Cohen, S.N.4
  • 36
    • 0017619277 scopus 로고
    • Genetic determination of methylenomycin synthesis by the SCP1 plasmid of Streptomyces coelicolor A3(2)
    • Kirby, R., and D. A. Hopwood. 1977. Genetic determination of methylenomycin synthesis by the SCP1 plasmid of Streptomyces coelicolor A3(2). J. Gen. Microbiol. 98:239-252.
    • (1977) J. Gen. Microbiol. , vol.98 , pp. 239-252
    • Kirby, R.1    Hopwood, D.A.2
  • 37
    • 77951616259 scopus 로고    scopus 로고
    • Putative TetR family transcriptional regulator SCO1712 encodes an antibiotic downregulator in Streptomyces coelicolor
    • Lee, H. N., J. Huang, J. H. Im, S. H. Kim, J. H. Noh, S. N. Cohen, and E. S. Kim. 2010. Putative TetR family transcriptional regulator SCO1712 encodes an antibiotic downregulator in Streptomyces coelicolor. Appl. Environ. Microbiol. 76:3039-3043.
    • (2010) Appl. Environ. Microbiol. , vol.76 , pp. 3039-3043
    • Lee, H.N.1    Huang, J.2    Im, J.H.3    Kim, S.H.4    Noh, J.H.5    Cohen, S.N.6    Kim, E.S.7
  • 38
    • 47849088463 scopus 로고    scopus 로고
    • Effects of extracellular ATP on the physiology of Streptomyces coelicolor A3(2)
    • Li, M., T. J. Kim, H. J. Kwon, and J. W. Suh. 2008. Effects of extracellular ATP on the physiology of Streptomyces coelicolor A3(2). FEMS Microbiol. Lett. 286:24-31.
    • (2008) FEMS Microbiol. Lett. , vol.286 , pp. 24-31
    • Li, M.1    Kim, T.J.2    Kwon, H.J.3    Suh, J.W.4
  • 39
    • 2342439799 scopus 로고    scopus 로고
    • A pair of two-component regulatory genes ecrA1/A2 in S. coelicolor
    • Li, Y. Q., P. L. Chen, S. F. Chen, D. Wu, and J. Zheng. 2004. A pair of two-component regulatory genes ecrA1/A2 in S. coelicolor. J. Zhejiang Univ. Sci. 5:173-179.
    • (2004) J. Zhejiang Univ. Sci. , vol.5 , pp. 173-179
    • Li, Y.Q.1    Chen, P.L.2    Chen, S.F.3    Wu, D.4    Zheng, J.5
  • 40
    • 0023001541 scopus 로고
    • Physical and genetic characterisation of the gene cluster for the antibiotic actinorhodin in Streptomyces coelicolor A3(2)
    • Malpartida, F., and D. A. Hopwood. 1986. Physical and genetic characterisation of the gene cluster for the antibiotic actinorhodin in Streptomyces coelicolor A3(2). Mol. Gen. Genet. 205:66-73.
    • (1986) Mol. Gen. Genet. , vol.205 , pp. 66-73
    • Malpartida, F.1    Hopwood, D.A.2
  • 41
    • 77952909070 scopus 로고    scopus 로고
    • Engineering of regulatory cascades and networks controlling antibiotic biosynthesis in Streptomyces
    • Martin, J. F., and P. Liras. 2010. Engineering of regulatory cascades and networks controlling antibiotic biosynthesis in Streptomyces. Curr. Opin. Microbiol. 13:263-273.
    • (2010) Curr. Opin. Microbiol. , vol.13 , pp. 263-273
    • Martin, J.F.1    Liras, P.2
  • 42
    • 15444380824 scopus 로고    scopus 로고
    • Environmental DNA fragment conferring early and increased sporulation and antibiotic production in Streptomyces species
    • Martinez, A., S. J. Kolvek, J. Hopke, C. L. Yip, and M. S. Osburne. 2005. Environmental DNA fragment conferring early and increased sporulation and antibiotic production in Streptomyces species. Appl. Environ. Microbiol. 71:1638-1641.
    • (2005) Appl. Environ. Microbiol. , vol.71 , pp. 1638-1641
    • Martinez, A.1    Kolvek, S.J.2    Hopke, J.3    Yip, C.L.4    Osburne, M.S.5
  • 43
    • 37049019211 scopus 로고    scopus 로고
    • Regulation of antibiotic biosynthesis in Streptomycetes
    • (In Ukranian.)
    • Matseliukh, B. P. 2006. Regulation of antibiotic biosynthesis in Streptomycetes. Mikrobiol. Z. 68:85-95. (In Ukranian.)
    • (2006) Mikrobiol. Z. , vol.68 , pp. 85-95
    • Matseliukh, B.P.1
  • 44
    • 34447560037 scopus 로고    scopus 로고
    • Phosphorylated AbsA2 negatively regulates antibiotic production in Streptomyces coelicolor through interactions with pathway-specific regulatory gene promoters
    • McKenzie, N. L., and J. R. Nodwell. 2007. Phosphorylated AbsA2 negatively regulates antibiotic production in Streptomyces coelicolor through interactions with pathway-specific regulatory gene promoters. J. Bacteriol. 189: 5284-5292.
    • (2007) J. Bacteriol. , vol.189 , pp. 5284-5292
    • McKenzie, N.L.1    Nodwell, J.R.2
  • 45
    • 50249163201 scopus 로고    scopus 로고
    • A bistable gene switch for antibiotic biosyn thesis: The butyrolactone regulon in Streptomyces coelicolor
    • Mehra, S., S. Charaniya, E. Takano, and W. S. Hu. 2008. A bistable gene switch for antibiotic biosynthesis: the butyrolactone regulon in Streptomyces coelicolor. PLoS One 3:e2724.
    • (2008) PLoS One , vol.3
    • Mehra, S.1    Charaniya, S.2    Takano, E.3    Hu, W.S.4
  • 46
    • 0030593468 scopus 로고    scopus 로고
    • Over-production of proteins in Escherichia coli: Mutant hosts that allow synthesis of some membrane proteins and globular proteins at high levels
    • Miroux, B., and J. E. Walker. 1996. Over-production of proteins in Escherichia coli: mutant hosts that allow synthesis of some membrane proteins and globular proteins at high levels. J. Mol. Biol. 260:289-298.
    • (1996) J. Mol. Biol. , vol.260 , pp. 289-298
    • Miroux, B.1    Walker, J.E.2
  • 47
    • 0024341196 scopus 로고
    • A vector system with temperature-sensitive replication for gene disruption and mutational cloning in streptomycetes
    • Muth, G., B. Nussbaumer, W. Wohlleben, and A. Pühler. 1989. A vector system with temperature-sensitive replication for gene disruption and mutational cloning in streptomycetes. Mol. Gen. Genet. 219:341-348.
    • (1989) Mol. Gen. Genet. , vol.219 , pp. 341-348
    • Muth, G.1    Nussbaumer, B.2    Wohlleben, W.3    Pühler, A.4
  • 48
    • 0031859952 scopus 로고    scopus 로고
    • Involvement of two A-factor receptor homologues in Streptomyces coelicolor A3(2) in the regulation of secondary metabolism and morphogenesis
    • Onaka, H., T. Nakagawa, and S. Horinouchi. 1998. Involvement of two A-factor receptor homologues in Streptomyces coelicolor A3(2) in the regulation of secondary metabolism and morphogenesis. Mol. Microbiol. 28:743-753.
    • (1998) Mol. Microbiol. , vol.28 , pp. 743-753
    • Onaka, H.1    Nakagawa, T.2    Horinouchi, S.3
  • 49
    • 63849138962 scopus 로고    scopus 로고
    • Characterization of rrdA, a TetR family protein gene involved in the regulation of secondary metabolism in Streptomyces coelicolor
    • Ou, X., B. Zhang, L. Zhang, G. Zhao, and X. Ding. 2009. Characterization of rrdA, a TetR family protein gene involved in the regulation of secondary metabolism in Streptomyces coelicolor. Appl. Environ. Microbiol. 75:2158-2165.
    • (2009) Appl. Environ. Microbiol. , vol.75 , pp. 2158-2165
    • Ou, X.1    Zhang, B.2    Zhang, L.3    Zhao, G.4    Ding, X.5
  • 50
    • 33846678395 scopus 로고    scopus 로고
    • A cryptic type I polyketide synthase (cpk) gene cluster in Streptomyces coelicolor A3(2)
    • Pawlik, K., M. Kotowska, K. F. Chater, K. Kuczek, and E. Takano. 2007. A cryptic type I polyketide synthase (cpk) gene cluster in Streptomyces coelicolor A3(2). Arch. Microbiol. 187:87-99.
    • (2007) Arch. Microbiol. , vol.187 , pp. 87-99
    • Pawlik, K.1    Kotowska, M.2    Chater, K.F.3    Kuczek, K.4    Takano, E.5
  • 52
    • 0031872416 scopus 로고    scopus 로고
    • A developmentally regulated gene encoding a repressorlike protein is essential for sporulation in Streptomyces coelicolor A3(2)
    • Ryding, N. J., G. H. Kelemen, C. A. Whatling, K. Flardh, M. J. Buttner, and K. F. Chater. 1998. A developmentally regulated gene encoding a repressorlike protein is essential for sporulation in Streptomyces coelicolor A3(2). Mol. Microbiol. 29:343-357.
    • (1998) Mol. Microbiol. , vol.29 , pp. 343-357
    • Ryding, N.J.1    Kelemen, G.H.2    Whatling, C.A.3    Flardh, K.4    Buttner, M.J.5    Chater, K.F.6
  • 55
    • 0038284769 scopus 로고    scopus 로고
    • The two-component PhoR-PhoP system controls both primary metabolism and secondary metabolite biosynthesis in Streptomyces lividans
    • Sola-Landa, A., R. S. Moura, and J. F. Martin. 2003. The two-component PhoR-PhoP system controls both primary metabolism and secondary metabolite biosynthesis in Streptomyces lividans. Proc. Natl. Acad. Sci. U. S. A. 100:6133-6138.
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 6133-6138
    • Sola-Landa, A.1    Moura, R.S.2    Martin, J.F.3
  • 56
    • 0141891355 scopus 로고    scopus 로고
    • Identification of three new genes involved in morphogenesis and antibiotic production in Streptomyces coelicolor
    • Sprusansky, O., L. Zhou, S. Jordan, J. White, and J. Westpheling. 2003. Identification of three new genes involved in morphogenesis and antibiotic production in Streptomyces coelicolor. J. Bacteriol. 185:6147-6157.
    • (2003) J. Bacteriol. , vol.185 , pp. 6147-6157
    • Sprusansky, O.1    Zhou, L.2    Jordan, S.3    White, J.4    Westpheling, J.5
  • 57
    • 0026549146 scopus 로고
    • Compilation and analysis of DNA sequences associated with apparent streptomycete promoters
    • Strohl, W. R. 1992. Compilation and analysis of DNA sequences associated with apparent streptomycete promoters. Nucleic Acids Res. 20:961-974.
    • (1992) Nucleic Acids Res. , vol.20 , pp. 961-974
    • Strohl, W.R.1
  • 60
    • 53149124737 scopus 로고    scopus 로고
    • Ligand recognition by ActR, a TetR-like regulator of actinorhodin export
    • Tahlan, K., Z. Yu, Y. Xu, A. R. Davidson, and J. R. Nodwell. 2008. Ligand recognition by ActR, a TetR-like regulator of actinorhodin export. J. Mol. Biol. 383:753-761.
    • (2008) J. Mol. Biol. , vol.383 , pp. 753-761
    • Tahlan, K.1    Yu, Z.2    Xu, Y.3    Davidson, A.R.4    Nodwell, J.R.5
  • 61
    • 0035788803 scopus 로고    scopus 로고
    • A complex role for the gamma-butyrolactone SCB1 in regulating antibiotic production in Streptomyces coelicolor A3(2)
    • Takano, E., R. Chakraburtty, T. Nihira, Y. Yamada, and M. J. Bibb. 2001. A complex role for the gamma-butyrolactone SCB1 in regulating antibiotic production in Streptomyces coelicolor A3(2). Mol. Microbiol. 41:1015-1028.
    • (2001) Mol. Microbiol. , vol.41 , pp. 1015-1028
    • Takano, E.1    Chakraburtty, R.2    Nihira, T.3    Yamada, Y.4    Bibb, M.J.5
  • 62
    • 0026784840 scopus 로고
    • Transcriptional regulation of the redD transcriptional activator gene accounts for growth-phase-dependent production of the antibiotic undecylprodigiosin in Streptomyces coelicolor A3(2)
    • Takano, E., H. C. Gramajo, E. Strauch, N. Andres, J. White, and M. J. Bibb. 1992. Transcriptional regulation of the redD transcriptional activator gene accounts for growth-phase-dependent production of the antibiotic undecylprodigiosin in Streptomyces coelicolor A3(2). Mol. Microbiol. 6:2797-2804.
    • (1992) Mol. Microbiol. , vol.6 , pp. 2797-2804
    • Takano, E.1    Gramajo, H.C.2    Strauch, E.3    Andres, N.4    White, J.5    Bibb, M.J.6
  • 63
    • 20244388405 scopus 로고    scopus 로고
    • A bacterial hormone (the SCB1) directly controls the expression of a pathway-specific regulatory gene in the cryptic type I polyketide biosynthetic gene cluster of Streptomyces coelicolor
    • Takano, E., H. Kinoshita, V. Mersinias, G. Bucca, G. Hotchkiss, T. Nihira, C. P. Smith, M. Bibb, W. Wohlleben, and K. Chater. 2005. A bacterial hormone (the SCB1) directly controls the expression of a pathway-specific regulatory gene in the cryptic type I polyketide biosynthetic gene cluster of Streptomyces coelicolor. Mol. Microbiol. 56:465-479.
    • (2005) Mol. Microbiol. , vol.56 , pp. 465-479
    • Takano, E.1    Kinoshita, H.2    Mersinias, V.3    Bucca, G.4    Hotchkiss, G.5    Nihira, T.6    Smith, C.P.7    Bibb, M.8    Wohlleben, W.9    Chater, K.10
  • 64
    • 38449097896 scopus 로고    scopus 로고
    • The Streptomyces coelicolor GlnR regulon: Identification of new GlnR targets and evidence for a central role of GlnR in nitrogen metabolism in actinomycetes
    • Tiffert, Y., P. Supra, R. Wurm, W. Wohlleben, R. Wagner, and J. Reuther. 2008. The Streptomyces coelicolor GlnR regulon: Identification of new GlnR targets and evidence for a central role of GlnR in nitrogen metabolism in actinomycetes. Mol. Microbiol. 67:861-880.
    • (2008) Mol. Microbiol. , vol.67 , pp. 861-880
    • Tiffert, Y.1    Supra, P.2    Wurm, R.3    Wohlleben, W.4    Wagner, R.5    Reuther, J.6
  • 65
    • 26244432061 scopus 로고    scopus 로고
    • Transcriptional activation of the pathway-specific regulator of the actinorhodin biosynthetic genes in Streptomyces coelicolor
    • Uguru, G. C., K. E. Stephens, J. A. Stead, J. E. Towle, S. Baumberg, and K. J. McDowall. 2005. Transcriptional activation of the pathway-specific regulator of the actinorhodin biosynthetic genes in Streptomyces coelicolor. Mol. Microbiol. 58:131-150.
    • (2005) Mol. Microbiol. , vol.58 , pp. 131-150
    • Uguru, G.C.1    Stephens, K.E.2    Stead, J.A.3    Towle, J.E.4    Baumberg, S.5    McDowall, K.J.6
  • 66
    • 0032832381 scopus 로고    scopus 로고
    • An AfsK/AfsR system involved in the response of aerial mycelium formation to glucose in Streptomyces griseus
    • Umeyama, T., P. C. Lee, K. Ueda, and S. Horinouchi. 1999. An AfsK/AfsR system involved in the response of aerial mycelium formation to glucose in Streptomyces griseus. Microbiology 145:2281-2292.
    • (1999) Microbiology , vol.145 , pp. 2281-2292
    • Umeyama, T.1    Lee, P.C.2    Ueda, K.3    Horinouchi, S.4
  • 67
    • 0030273880 scopus 로고    scopus 로고
    • Expression of the Streptomyces coelicolor A3(2) ptpA gene encoding a phosphotyrosine protein phosphatase leads to overproduction of secondary metabolites in S. lividans
    • Umeyama, T., Y. Tanabe, B. D. Aigle, and S. Horinouchi. 1996. Expression of the Streptomyces coelicolor A3(2) ptpA gene encoding a phosphotyrosine protein phosphatase leads to overproduction of secondary metabolites in S. lividans. FEMS Microbiol. Lett. 144:177-184.
    • (1996) FEMS Microbiol. Lett. , vol.144 , pp. 177-184
    • Umeyama, T.1    Tanabe, Y.2    Aigle, B.D.3    Horinouchi, S.4
  • 68
    • 41549096949 scopus 로고    scopus 로고
    • Expression and characterization of the Streptomyces coelicolor serine/threonine protein kinase PkaD
    • Urabe, H., N. Aoyagi, H. Ogawara, and K. Motojima. 2008. Expression and characterization of the Streptomyces coelicolor serine/threonine protein kinase PkaD. Biosci. Biotechnol. Biochem. 72:778-785.
    • (2008) Biosci. Biotechnol. Biochem. , vol.72 , pp. 778-785
    • Urabe, H.1    Aoyagi, N.2    Ogawara, H.3    Motojima, K.4
  • 69
    • 0028171561 scopus 로고
    • AfsR2: A previously undetected gene encoding a 63-amino-acid protein that stimulates antibiotic production in Streptomyces lividans
    • Vogtli, M., P. C. Chang, and S. N. Cohen. 1994. afsR2: A previously undetected gene encoding a 63-amino-acid protein that stimulates antibiotic production in Streptomyces lividans. Mol. Microbiol. 14:643-653.
    • (1994) Mol. Microbiol. , vol.14 , pp. 643-653
    • Vogtli, M.1    Chang, P.C.2    Cohen, S.N.3
  • 70
    • 0031016476 scopus 로고    scopus 로고
    • BldA dependence of undecylprodigiosin production in Streptomyces coelicolor A3(2) involves a pathway-specific regulatory cascade
    • White, J., and M. Bibb. 1997. bldA dependence of undecylprodigiosin production in Streptomyces coelicolor A3(2) involves a pathway-specific regulatory cascade. J. Bacteriol. 179:627-633.
    • (1997) J. Bacteriol. , vol.179 , pp. 627-633
    • White, J.1    Bibb, M.2
  • 71
    • 0033748094 scopus 로고    scopus 로고
    • Footprinting with an automated capillary DNA sequencer
    • 1038, 1040-1041
    • Yindeeyoungyeon, W., and M. A. Schell. 2000. Footprinting with an automated capillary DNA sequencer. Biotechniques 29:1034-1036, 1038, 1040-1041.
    • (2000) Biotechniques , vol.29 , pp. 1034-1036
    • Yindeeyoungyeon, W.1    Schell, M.A.2
  • 72
    • 43749088055 scopus 로고    scopus 로고
    • Biosynthesis of the sesquiterpene antibiotic albaflavenone in Streptomyces coelicolor A3(2)
    • Zhao, B., X. Lin, L. Lei, D. C. Lamb, S. L. Kelly, M. R. Waterman, and D. E. Cane. 2008. Biosynthesis of the sesquiterpene antibiotic albaflavenone in Streptomyces coelicolor A3(2). J. Biol. Chem. 283:8183-8189.
    • (2008) J. Biol. Chem. , vol.283 , pp. 8183-8189
    • Zhao, B.1    Lin, X.2    Lei, L.3    Lamb, D.C.4    Kelly, S.L.5    Waterman, M.R.6    Cane, D.E.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.