NADPH phagocyte oxidase knockout mice control trypanosoma cruzi proliferation, but develop circulatory collapse and succumb to infection

PLoS Neglected Tropical Diseases

Volumn 6, Issue 2, 2012, Pages

  Santiago, Helton C ^a,f   Lombana, Claudia Z Gonzalez ^a,g   Macedo, Juan P ^a   Utsch, Lara ^a   Tafuri, Wagner L ^a   Campagnole Santos, Maria José ^a   Alves, Rosana O ^b   Alves Filho, José C F ^c   Romanha, Alvaro J ^b   Cunha, Fernando Queiroz ^c   Teixeira, Mauro M ^a   Radi, Rafael ^d   Vieira, Leda Q ^a,e  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b INSTITUTO OSWALDO CRUZ   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

^d UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

^e FEDERAL UNIVERSITY OF OURO PRETO   (Brazil)

^f NATIONAL INSTITUTES OF HEALTH   (United States)

^g UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; AMYLASE; GAMMA INTERFERON; N [3 (AMINOMETHYL) BENZYL] ACETAMIDINE; NITRATE; NITRITE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; CYBB PROTEIN, MOUSE; MEMBRANE PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CHAGAS DISEASE; CHRONIC GRANULOMATOUS DISEASE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; IMMUNE RESPONSE; INFECTION SENSITIVITY; KNOCKOUT MOUSE; MALE; MEAN ARTERIAL PRESSURE; MORTALITY; MOUSE; NONHUMAN; PARASITEMIA; PHAGOCYTE; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SHOCK; SINGLE DRUG DOSE; TRYPANOSOMA CRUZI; ANIMAL; BLOOD; C57BL MOUSE; CELL CULTURE; DISEASE MODEL; ENZYMOLOGY; IMMUNOLOGY; MONONUCLEAR CELL; MOUSE MUTANT; SECRETION; SPLEEN; SURVIVAL;

ANIMALS; CELLS, CULTURED; CHAGAS DISEASE; DISEASE MODELS, ANIMAL; FEMALE; INTERFERON-GAMMA; LEUKOCYTES, MONONUCLEAR; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NADPH OXIDASE; PARASITEMIA; PHAGOCYTES; SHOCK; SPLEEN; SURVIVAL ANALYSIS; TRYPANOSOMA CRUZI; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84857886837     PISSN: 19352727     EISSN: 19352735     Source Type: Journal    
DOI: 10.1371/journal.pntd.0001492     Document Type: Article

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