-
1
-
-
0034527909
-
SETA is a multifunctional adapter protein with three SH3 domains that binds Grb2, Cbl, and the novel SB1 proteins
-
Borinstein SC, et al. 2000. SETA is a multifunctional adapter protein with three SH3 domains that binds Grb2, Cbl, and the novel SB1 proteins. Cell Signal. 12:769-779.
-
(2000)
Cell Signal.
, vol.12
, pp. 769-779
-
-
Borinstein, S.C.1
-
2
-
-
33745842895
-
Identification of a novel inhibitory actin-capping protein binding motif in CD2-associated protein
-
Bruck S, et al. 2006. Identification of a novel inhibitory actin-capping protein binding motif in CD2-associated protein. J. Biol. Chem. 281:19196-19203.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 19196-19203
-
-
Bruck, S.1
-
3
-
-
0037167167
-
Organization of the mouse Ruk locus and expression of isoforms in mouse tissues
-
Buchman VL, Luke C, Borthwick EB, Gout I, Ninkina N. 2002. Organization of the mouse Ruk locus and expression of isoforms in mouse tissues. Gene 295:13-17.
-
(2002)
Gene
, vol.295
, pp. 13-17
-
-
Buchman, V.L.1
Luke, C.2
Borthwick, E.B.3
Gout, I.4
Ninkina, N.5
-
4
-
-
34047103990
-
C-terminal modifications regulate MDM2 dissociation and nuclear export of p53
-
Carter S, Bischof O, Dejean A, Vousden KH. 2007. C-terminal modifications regulate MDM2 dissociation and nuclear export of p53. Nat. Cell Biol. 9:428-435.
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 428-435
-
-
Carter, S.1
Bischof, O.2
Dejean, A.3
Vousden, K.H.4
-
5
-
-
33847737020
-
Ubc9 interacts with Lu/BCAM adhesion glycoproteins and regulates their stability at the membrane of polarized MDCK cells
-
Collec E, et al. 2007. Ubc9 interacts with Lu/BCAM adhesion glycoproteins and regulates their stability at the membrane of polarized MDCK cells. Biochem. J. 402:311-319.
-
(2007)
Biochem. J.
, vol.402
, pp. 311-319
-
-
Collec, E.1
-
6
-
-
26444603772
-
Two rounds of whole genome duplication in the ancestral vertebrate
-
Dehal P, Boore JL. 2005. Two rounds of whole genome duplication in the ancestral vertebrate. PLoS Biol. 3:e314.
-
(2005)
PLoS Biol.
, vol.3
-
-
Dehal, P.1
Boore, J.L.2
-
7
-
-
0037010186
-
CIN85/CMS family of adaptor molecules
-
Dikic I. 2002. CIN85/CMS family of adaptor molecules. FEBS Lett. 529:110-115.
-
(2002)
FEBS Lett.
, vol.529
, pp. 110-115
-
-
Dikic, I.1
-
8
-
-
0028282555
-
Backbone dynamics of a free and phosphopeptide-complexed Src homology 2 domain studied by 15N NMR relaxation
-
Farrow NA, et al. 1994. Backbone dynamics of a free and phosphopeptide-complexed Src homology 2 domain studied by 15N NMR relaxation. Biochemistry 33:5984-6003.
-
(1994)
Biochemistry
, vol.33
, pp. 5984-6003
-
-
Farrow, N.A.1
-
9
-
-
24644522876
-
Stabilization of PML nuclear localization by conjugation and oligomerization of SUMO-3
-
Fu C, et al. 2005. Stabilization of PML nuclear localization by conjugation and oligomerization of SUMO-3. Oncogene 24:5401-5413.
-
(2005)
Oncogene
, vol.24
, pp. 5401-5413
-
-
Fu, C.1
-
10
-
-
34547782856
-
Structure and function analysis of the CMS/CIN85 protein family identifies actinbundling properties and heterotypic-complex formation
-
Gaidos G, Soni S, Oswald DJ, Toselli PA, Kirsch KH. 2007. Structure and function analysis of the CMS/CIN85 protein family identifies actinbundling properties and heterotypic-complex formation. J. Cell Sci. 120:2366-2377.
-
(2007)
J. Cell Sci.
, vol.120
, pp. 2366-2377
-
-
Gaidos, G.1
Soni, S.2
Oswald, D.J.3
Toselli, P.A.4
Kirsch, K.H.5
-
12
-
-
0034254677
-
Negative regulation of PI 3-kinase by Ruk, a novel adaptor protein
-
Gout I, et al. 2000. Negative regulation of PI 3-kinase by Ruk, a novel adaptor protein. EMBO J. 19:4015-4025.
-
(2000)
EMBO J.
, vol.19
, pp. 4015-4025
-
-
Gout, I.1
-
13
-
-
23844539615
-
CD2-associated protein (CD2AP) expression in podocytes rescues lethality of CD2AP deficiency
-
Grunkemeyer JA, Kwoh C, Huber TB, Shaw AS. 2005. CD2-associated protein (CD2AP) expression in podocytes rescues lethality of CD2AP deficiency. J. Biol. Chem. 280:29677-29681.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 29677-29681
-
-
Grunkemeyer, J.A.1
Kwoh, C.2
Huber, T.B.3
Shaw, A.S.4
-
14
-
-
0037125983
-
Cbl-directed monoubiquitination of CIN85 is involved in regulation of ligand-induced degradation of EGF receptors
-
Haglund K, Shimokawa N, Szymkiewicz I, Dikic I. 2002. Cbl-directed monoubiquitination of CIN85 is involved in regulation of ligand-induced degradation of EGF receptors. Proc. Natl. Acad. Sci. U. S. A. 99:12191-12196.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 12191-12196
-
-
Haglund, K.1
Shimokawa, N.2
Szymkiewicz, I.3
Dikic, I.4
-
15
-
-
77953464378
-
Emerging roles of Ruk/CIN85 in vesicle-mediated transport, adhesion, migration and malignancy
-
Havrylov S, Redowicz MJ, Buchman VL. 2010. Emerging roles of Ruk/CIN85 in vesicle-mediated transport, adhesion, migration and malignancy. Traffic 11:721-731.
-
(2010)
Traffic
, vol.11
, pp. 721-731
-
-
Havrylov, S.1
Redowicz, M.J.2
Buchman, V.L.3
-
16
-
-
77950500990
-
Structural characterization of a capping protein interaction motif defines a family of actin filament regulators
-
Hernandez-Valladares M, et al. 2010. Structural characterization of a capping protein interaction motif defines a family of actin filament regulators. Nat. Struct. Mol. Biol. 17:497-503.
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 497-503
-
-
Hernandez-Valladares, M.1
-
17
-
-
0344305376
-
Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress
-
Huang TT, Wuerzberger-Davis SM, Wu ZH, Miyamoto S. 2003. Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress. Cell 115:565-576.
-
(2003)
Cell
, vol.115
, pp. 565-576
-
-
Huang, T.T.1
Wuerzberger-Davis, S.M.2
Wu, Z.H.3
Miyamoto, S.4
-
18
-
-
0038788840
-
Nephrin and CD2AP associate with phosphoinositide 3-OH kinase and stimulate AKT-dependent signaling
-
Huber TB, et al. 2003. Nephrin and CD2AP associate with phosphoinositide 3-OH kinase and stimulate AKT-dependent signaling. Mol. Cell Biol. 23:4917-4928.
-
(2003)
Mol. Cell Biol.
, vol.23
, pp. 4917-4928
-
-
Huber, T.B.1
-
19
-
-
3943099375
-
Protein modification by SUMO
-
Johnson ES. 2004. Protein modification by SUMO. Annu. Rev. Biochem. 73:355-382.
-
(2004)
Annu. Rev. Biochem.
, vol.73
, pp. 355-382
-
-
Johnson, E.S.1
-
20
-
-
26044447158
-
Rho mediates endocytosis of epidermal growth factor receptor through phosphorylation of endophilin A1 by Rho-kinase
-
Kaneko T, et al. 2005. Rho mediates endocytosis of epidermal growth factor receptor through phosphorylation of endophilin A1 by Rho-kinase. Genes Cells 10:973-987.
-
(2005)
Genes Cells
, vol.10
, pp. 973-987
-
-
Kaneko, T.1
-
22
-
-
0032015551
-
Positionally cloned gene for a novel glomerular protein-nephrin-is mutated in congenital nephrotic syndrome
-
Kestila M, et al. 1998. Positionally cloned gene for a novel glomerular protein-nephrin-is mutated in congenital nephrotic syndrome. Mol. Cell 1:575-582.
-
(1998)
Mol. Cell
, vol.1
, pp. 575-582
-
-
Kestila, M.1
-
24
-
-
4644302353
-
The c-Cbl/CD2AP complex regulates VEGF-induced endocytosis and degradation of Flt-1 (VEGFR-1)
-
Kobayashi S, Sawano A, Nojima Y, Shibuya M, Maru Y. 2004. The c-Cbl/CD2AP complex regulates VEGF-induced endocytosis and degradation of Flt-1 (VEGFR-1). FASEB J. 18:929-931.
-
(2004)
FASEB J.
, vol.18
, pp. 929-931
-
-
Kobayashi, S.1
Sawano, A.2
Nojima, Y.3
Shibuya, M.4
Maru, Y.5
-
25
-
-
33749376767
-
CFBP is a novel tyrosine-phosphorylated protein that might function as a regulator of CIN85/CD2AP
-
Konishi H, et al. 2006. CFBP is a novel tyrosine-phosphorylated protein that might function as a regulator of CIN85/CD2AP. J. Biol. Chem. 281:28919-28931.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 28919-28931
-
-
Konishi, H.1
-
26
-
-
3042765835
-
CIN85 associates with multiple effectors controlling intracellular trafficking of epidermal growth factor receptors
-
Kowanetz K, et al. 2004. CIN85 associates with multiple effectors controlling intracellular trafficking of epidermal growth factor receptors. Mol. Biol. Cell 15:3155-3166.
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 3155-3166
-
-
Kowanetz, K.1
-
27
-
-
0041731797
-
SUMO-1/Ubc9 promotes nuclear accumulation and metabolic stability of tumor suppressor Smad4
-
Lin X, Liang M, Liang YY, Brunicardi FC, Feng XH. 2003. SUMO-1/Ubc9 promotes nuclear accumulation and metabolic stability of tumor suppressor Smad4. J. Biol. Chem. 278:31043-31048.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 31043-31048
-
-
Lin, X.1
Liang, M.2
Liang, Y.Y.3
Brunicardi, F.C.4
Feng, X.H.5
-
28
-
-
0038054467
-
Opposed regulation of corepressor CtBP by SUMOylation and PDZ binding
-
Lin X, et al. 2003. Opposed regulation of corepressor CtBP by SUMOylation and PDZ binding. Mol. Cell 11:1389-1396.
-
(2003)
Mol. Cell
, vol.11
, pp. 1389-1396
-
-
Lin, X.1
-
29
-
-
0038498066
-
A Cortactin-CD2-associated protein (CD2AP) complex provides a novel link between epidermal growth factor receptor endocytosis and the actin cytoskeleton
-
Lynch DK, et al. 2003. A Cortactin-CD2-associated protein (CD2AP) complex provides a novel link between epidermal growth factor receptor endocytosis and the actin cytoskeleton. J. Biol. Chem. 278:21805-21813.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 21805-21813
-
-
Lynch, D.K.1
-
31
-
-
33846864019
-
Expression of adaptor protein Ruk/CIN85 isoforms in cell lines of various tissue origins and human melanoma
-
Mayevska O, et al. 2006. Expression of adaptor protein Ruk/CIN85 isoforms in cell lines of various tissue origins and human melanoma. Exp. Oncol. 28:275-281.
-
(2006)
Exp. Oncol.
, vol.28
, pp. 275-281
-
-
Mayevska, O.1
-
32
-
-
44449109533
-
Mechanism and consequences for paralog-specific sumoylation of ubiquitin-specific protease 25
-
Meulmeester E, Kunze M, Hsiao HH, Urlaub H, Melchior F. 2008. Mechanism and consequences for paralog-specific sumoylation of ubiquitin-specific protease 25. Mol. Cell 30:610-619.
-
(2008)
Mol. Cell
, vol.30
, pp. 610-619
-
-
Meulmeester, E.1
Kunze, M.2
Hsiao, H.H.3
Urlaub, H.4
Melchior, F.5
-
34
-
-
44449159295
-
SUMO takes control of a ubiquitin-specific protease
-
Mohideen F, Lima CD. 2008. SUMO takes control of a ubiquitin-specific protease. Mol. Cell 30:539-540.
-
(2008)
Mol. Cell
, vol.30
, pp. 539-540
-
-
Mohideen, F.1
Lima, C.D.2
-
35
-
-
1942437991
-
SUMO: a regulator of gene expression and genome integrity
-
Muller S, Ledl A, Schmidt D. 2004. SUMO: a regulator of gene expression and genome integrity. Oncogene 23:1998-2008.
-
(2004)
Oncogene
, vol.23
, pp. 1998-2008
-
-
Muller, S.1
Ledl, A.2
Schmidt, D.3
-
36
-
-
77957986445
-
The serine/arginine-rich protein SF2/ASF regulates protein sumoylation
-
Pelisch F, et al. 2010. The serine/arginine-rich protein SF2/ASF regulates protein sumoylation. Proc. Natl. Acad. Sci. U. S. A. 107:16119-16124.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 16119-16124
-
-
Pelisch, F.1
-
37
-
-
0034945410
-
Animal phylogeny and the ancestry of bilaterians: inferences from morphology and 18S rDNA gene sequences
-
Peterson KJ, Eernisse DJ. 2001. Animal phylogeny and the ancestry of bilaterians: inferences from morphology and 18S rDNA gene sequences. Evol. Dev. 3:170-205.
-
(2001)
Evol. Dev.
, vol.3
, pp. 170-205
-
-
Peterson, K.J.1
Eernisse, D.J.2
-
38
-
-
4744370425
-
The RanBP2 SUMO E3 ligase is neither
-
Pichler A, Knipscheer P, Saitoh H, Sixma TK, Melchior F. 2004. The RanBP2 SUMO E3 ligase is neither. Nat. Struct. Mol. Biol. 11:984-991.
-
(2004)
Nat. Struct. Mol. Biol.
, vol.11
, pp. 984-991
-
-
Pichler, A.1
Knipscheer, P.2
Saitoh, H.3
Sixma, T.K.4
Melchior, F.5
-
39
-
-
0034915764
-
Mechanisms underlying ubiquitination
-
Pickart CM. 2001. Mechanisms underlying ubiquitination. Annu. Rev. Biochem. 70:503-533.
-
(2001)
Annu. Rev. Biochem.
, vol.70
, pp. 503-533
-
-
Pickart, C.M.1
-
40
-
-
0035164681
-
The murine nephrin gene is specifically expressed in kidney, brain and pancreas: inactivation of the gene leads to massive proteinuria and neonatal death
-
Putaala H, Soininen R, Kilpelainen P, Wartiovaara J, Tryggvason K. 2001. The murine nephrin gene is specifically expressed in kidney, brain and pancreas: inactivation of the gene leads to massive proteinuria and neonatal death. Hum. Mol. Genet. 10:1-8.
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 1-8
-
-
Putaala, H.1
Soininen, R.2
Kilpelainen, P.3
Wartiovaara, J.4
Tryggvason, K.5
-
41
-
-
0035877693
-
The small ubiquitin-like modifier-1 (SUMO-1) consensus sequence mediates Ubc9 binding and is essential for SUMO-1 modification
-
Sampson DA, Wang M, Matunis MJ. 2001. The small ubiquitin-like modifier-1 (SUMO-1) consensus sequence mediates Ubc9 binding and is essential for SUMO-1 modification. J. Biol. Chem. 276:21664-21669.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 21664-21669
-
-
Sampson, D.A.1
Wang, M.2
Matunis, M.J.3
-
42
-
-
36749023969
-
Regulation of the interaction of Disabled-1 with CIN85 by phosphorylation with Cyclin-dependent kinase 5
-
Sato Y, et al. 2007. Regulation of the interaction of Disabled-1 with CIN85 by phosphorylation with Cyclin-dependent kinase 5. Genes Cells 12:1315-1327.
-
(2007)
Genes Cells
, vol.12
, pp. 1315-1327
-
-
Sato, Y.1
-
43
-
-
77956880594
-
A Dyn2-CIN85 complex mediates degradative traffic of the EGFR by regulation of late endosomal budding
-
Schroeder B, Weller SG, Chen J, Billadeau D, McNiven MA. 2010. A Dyn2-CIN85 complex mediates degradative traffic of the EGFR by regulation of late endosomal budding. EMBO J. 29:3039-3053.
-
(2010)
EMBO J.
, vol.29
, pp. 3039-3053
-
-
Schroeder, B.1
Weller, S.G.2
Chen, J.3
Billadeau, D.4
McNiven, M.A.5
-
44
-
-
0035191415
-
CD2AP localizes to the slit diaphragm and binds to nephrin via a novel C-terminal domain
-
Shih NY, et al. 2001. CD2AP localizes to the slit diaphragm and binds to nephrin via a novel C-terminal domain. Am. J. Pathol. 159:2303-2308.
-
(2001)
Am. J. Pathol.
, vol.159
, pp. 2303-2308
-
-
Shih, N.Y.1
-
45
-
-
0037075547
-
Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors
-
Soubeyran P, Kowanetz K, Szymkiewicz I, Langdon WY, Dikic I. 2002. Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors. Nature 416:183-187.
-
(2002)
Nature
, vol.416
, pp. 183-187
-
-
Soubeyran, P.1
Kowanetz, K.2
Szymkiewicz, I.3
Langdon, W.Y.4
Dikic, I.5
-
46
-
-
0141625302
-
Solution structure of Vps27 UIM-ubiquitin complex important for endosomal sorting and receptor downregulation
-
Swanson KA, Kang RS, Stamenova SD, Hicke L, Radhakrishnan I. 2003. Solution structure of Vps27 UIM-ubiquitin complex important for endosomal sorting and receptor downregulation. EMBO J. 22:4597-4606.
-
(2003)
EMBO J.
, vol.22
, pp. 4597-4606
-
-
Swanson, K.A.1
Kang, R.S.2
Stamenova, S.D.3
Hicke, L.4
Radhakrishnan, I.5
-
47
-
-
0035929557
-
Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9
-
Tatham MH, et al. 2001. Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9. J. Biol. Chem. 276:35368-35374.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 35368-35374
-
-
Tatham, M.H.1
-
48
-
-
34147130656
-
CD2AP/CIN85 balance determines receptor tyrosine kinase signaling response in podocytes
-
Tossidou I, et al. 2007. CD2AP/CIN85 balance determines receptor tyrosine kinase signaling response in podocytes. J. Biol. Chem. 282:7457-7464.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 7457-7464
-
-
Tossidou, I.1
-
49
-
-
77955487681
-
CIN85/RukL is a novel binding partner of nephrin and podocin and mediates slit diaphragm turnover in podocytes
-
Tossidou I, et al. 2010. CIN85/RukL is a novel binding partner of nephrin and podocin and mediates slit diaphragm turnover in podocytes. J. Biol. Chem. 285:25285-25295.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 25285-25295
-
-
Tossidou, I.1
-
50
-
-
77953806001
-
Rac1 recruits the adapter protein CMS/CD2AP to cell-cell contacts
-
van Duijn TJ, Anthony EC, Hensbergen PJ, Deelder AM, Hordijk PL. 2010. Rac1 recruits the adapter protein CMS/CD2AP to cell-cell contacts. J. Biol. Chem. 285:20137-20146.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 20137-20146
-
-
van Duijn, T.J.1
Anthony, E.C.2
Hensbergen, P.J.3
Deelder, A.M.4
Hordijk, P.L.5
-
51
-
-
0036373920
-
Ruk is ubiquitinated but not degraded by the proteasome
-
Verdier F, et al. 2002. Ruk is ubiquitinated but not degraded by the proteasome. Eur. J. Biochem. 269:3402-3408.
-
(2002)
Eur. J. Biochem.
, vol.269
, pp. 3402-3408
-
-
Verdier, F.1
-
52
-
-
77957823973
-
A critical role of c-Cbl-interacting protein of 85 kDa in the development and progression of head and neck squamous cell carcinomas through the ras-ERK pathway
-
Wakasaki T, et al. 2010. A critical role of c-Cbl-interacting protein of 85 kDa in the development and progression of head and neck squamous cell carcinomas through the ras-ERK pathway. Neoplasia 12:789-796.
-
(2010)
Neoplasia
, vol.12
, pp. 789-796
-
-
Wakasaki, T.1
-
53
-
-
0034638634
-
Characterization of the CIN85 adaptor protein and identification of components involved in CIN85 complexes
-
Watanabe S, et al. 2000. Characterization of the CIN85 adaptor protein and identification of components involved in CIN85 complexes. Biochem. Biophys. Res. Commun. 278:167-174.
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.278
, pp. 167-174
-
-
Watanabe, S.1
-
54
-
-
33746806278
-
Coordinated regulation of AIB1 transcriptional activity by sumoylation and phosphorylation
-
Wu H, et al. 2006. Coordinated regulation of AIB1 transcriptional activity by sumoylation and phosphorylation. J. Biol. Chem. 281:21848-21856.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 21848-21856
-
-
Wu, H.1
-
55
-
-
33747838835
-
SUMOsp: a web server for sumoylation site prediction
-
Xue Y, Zhou F, Fu C, Xu Y, Yao X. 2006. SUMOsp: a web server for sumoylation site prediction. Nucleic Acids Res. 34:W254-W257.
-
(2006)
Nucleic Acids Res.
, vol.34
-
-
Xue, Y.1
Zhou, F.2
Fu, C.3
Xu, Y.4
Yao, X.5
-
56
-
-
0041669469
-
Dynamic interplay of the SUMO and ERK pathways in regulating Elk-1 transcriptional activity
-
Yang SH, Jaffray E, Hay RT, Sharrocks AD. 2003. Dynamic interplay of the SUMO and ERK pathways in regulating Elk-1 transcriptional activity. Mol. Cell 12:63-74.
-
(2003)
Mol. Cell
, vol.12
, pp. 63-74
-
-
Yang, S.H.1
Jaffray, E.2
Hay, R.T.3
Sharrocks, A.D.4
-
57
-
-
79952748284
-
ARAP1 association with CIN85 affects epidermal growth factor receptor endocytic trafficking
-
Yoon HY, Kales SC, Luo R, Lipkowitz S, Randazzo PA. 2011. ARAP1 association with CIN85 affects epidermal growth factor receptor endocytic trafficking. Biol. Cell 103:171-184.
-
(2011)
Biol. Cell
, vol.103
, pp. 171-184
-
-
Yoon, H.Y.1
Kales, S.C.2
Luo, R.3
Lipkowitz, S.4
Randazzo, P.A.5
|