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Volumn 442, Issue 3, 2012, Pages 649-659

Protein kinase D2 has a restricted but critical role in T-cell antigen receptor signalling in mature T-cells

Author keywords

Cytokine; Lymphocyte; Pre cell antigen receptor; Protein kinase D (PKD); T cell antigen receptor (TCR); Thymus

Indexed keywords

MESSENGER RNA; PROTEIN KINASE D2; PROTEIN SERINE THREONINE KINASE; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN; UNCLASSIFIED DRUG;

EID: 84857855150     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20111700     Document Type: Article
Times cited : (21)

References (44)
  • 1
    • 61849128182 scopus 로고    scopus 로고
    • T-cell receptor proximal signaling via the Src-family kinases, Lck and Fyn, influences T-cell activation, differentiation, and tolerance
    • Salmond, R. J., Filby, A., Qureshi, I., Caserta, S. and Zamoyska, R. (2009) T-cell receptor proximal signaling via the Src-family kinases, Lck and Fyn, influences T-cell activation, differentiation, and tolerance. Immunol. Rev. 228, 9-22
    • (2009) Immunol. Rev. , vol.228 , pp. 9-22
    • Salmond, R.J.1    Filby, A.2    Qureshi, I.3    Caserta, S.4    Zamoyska, R.5
  • 2
    • 61849090213 scopus 로고    scopus 로고
    • New insights into the regulation and function of serine/threonine kinases in T lymphocytes
    • Matthews, S. A. and Cantrell, D. A. (2009) New insights into the regulation and function of serine/threonine kinases in T lymphocytes. Immunol. Rev. 228, 241-252
    • (2009) Immunol. Rev. , vol.228 , pp. 241-252
    • Matthews, S.A.1    Cantrell, D.A.2
  • 4
    • 33750094147 scopus 로고    scopus 로고
    • Disruption of diacylglycerol metabolism impairs the induction of T cell anergy
    • DOI 10.1038/ni1400, PII NI1400
    • Olenchock, B. A., Guo, R., Carpenter, J. H., Jordan, M., Topham, M. K., Koretzky, G. A. and Zhong, X. P. (2006) Disruption of diacylglycerol metabolism impairs the induction of T cell anergy. Nat. Immunol. 7, 1174-1181 (Pubitemid 44594313)
    • (2006) Nature Immunology , vol.7 , Issue.11 , pp. 1174-1181
    • Olenchock, B.A.1    Guo, R.2    Carpenter, J.H.3    Jordan, M.4    Topham, M.K.5    Koretzky, G.A.6    Zhong, X.-P.7
  • 7
    • 33646560593 scopus 로고    scopus 로고
    • Diacylglycerol and Protein Kinase D Localization during T Lymphocyte Activation
    • DOI 10.1016/j.immuni.2006.02.013, PII S107476130600210X
    • Spitaler, M., Emslie, E., Wood, C. D. and Cantrell, D. (2006) Diacylglycerol and protein kinase D localization during T lymphocyte activation. Immunity 24, 535-546 (Pubitemid 43728156)
    • (2006) Immunity , vol.24 , Issue.5 , pp. 535-546
    • Spitaler, M.1    Emslie, E.2    Wood, C.D.3    Cantrell, D.4
  • 8
    • 14044253572 scopus 로고    scopus 로고
    • Dual phospholipase C/diacylglycerol requirement for protein kinase D1 activation in lymphocytes
    • DOI 10.1074/jbc.M411564200
    • Wood, C. D., Marklund, U. and Cantrell, D. A. (2005) Dual phospholipase C/diacylglycerol requirement for protein kinase D1 activation in lymphocytes. J. Biol. Chem. 280, 6245-6251 (Pubitemid 40280110)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.7 , pp. 6245-6251
    • Wood, C.D.1    Marklund, U.2    Cantrell, D.A.3
  • 9
    • 79951745387 scopus 로고    scopus 로고
    • Protein kinase B controls transcriptional programs that direct cytotoxic T cell fate but is dispensable for T cell metabolism
    • Macintyre, A. N., Finlay, D., Preston, G., Sinclair, L. V., Waugh, C. M., Tamas, P., Feijoo, C., Okkenhaug, K. and Cantrell, D. A. (2011) Protein kinase B controls transcriptional programs that direct cytotoxic T cell fate but is dispensable for T cell metabolism. Immunity 34, 224-236
    • (2011) Immunity , vol.34 , pp. 224-236
    • Macintyre, A.N.1    Finlay, D.2    Preston, G.3    Sinclair, L.V.4    Waugh, C.M.5    Tamas, P.6    Feijoo, C.7    Okkenhaug, K.8    Cantrell, D.A.9
  • 11
    • 0033543570 scopus 로고    scopus 로고
    • Characterization of serine 916 as an in vivo autophosphorylation site for protein kinase D/protein kinase Cμ
    • Matthews, S. A., Rozengurt, E. and Cantrell, D. (1999) Characterization of serine 916 as an in vivo autophosphorylation site for protein kinase D/protein kinase Cμ. J. Biol. Chem. 274, 26543-26549
    • (1999) J. Biol. Chem. , vol.274 , pp. 26543-26549
    • Matthews, S.A.1    Rozengurt, E.2    Cantrell, D.3
  • 12
    • 3042627641 scopus 로고    scopus 로고
    • Induction of T cell development and establishment of T cell competence from embryonic stem cells differentiated in vitro
    • DOI 10.1038/ni1055
    • Schmitt, T. M., de Pooter, R. F., Gronski, M. A., Cho, S. K., Ohashi, P. S. and Zuniga-Pflucker, J. C. (2004) Induction of T cell development and establishment of T cell competence from embryonic stem cells differentiated in vitro. Nat. Immunol. 5, 410-417 (Pubitemid 38500090)
    • (2004) Nature Immunology , vol.5 , Issue.4 , pp. 410-417
    • Schmitt, T.M.1    De Pooter, R.F.2    Gronski, M.A.3    Cho, S.K.4    Ohashi, P.S.5    Zuniga-Pflucker, J.C.6
  • 13
    • 0142250491 scopus 로고    scopus 로고
    • Intracellular location and cell context-dependent function of protein kinase D
    • DOI 10.1016/S1074-7613(03)00260-7
    • Marklund, U., Lightfoot, K. and Cantrell, D. (2003) Intracellular location and cell context-dependent function of protein kinase D. Immunity 19, 491-501 (Pubitemid 37311431)
    • (2003) Immunity , vol.19 , Issue.4 , pp. 491-501
    • Marklund, U.1    Lightfoot, K.2    Cantrell, D.3
  • 14
    • 79952962027 scopus 로고    scopus 로고
    • Phosphoproteomic analysis reveals an intrinsic pathway for the regulation of histone deacetylase 7 that controls the function of cytotoxic T lymphocytes
    • Navarro, M. N., Goebel, J., Feijoo-Carnero, C., Morrice, N. and Cantrell, D. A. (2011) Phosphoproteomic analysis reveals an intrinsic pathway for the regulation of histone deacetylase 7 that controls the function of cytotoxic T lymphocytes. Nat. Immunol. 12, 352-361
    • (2011) Nat. Immunol. , vol.12 , pp. 352-361
    • Navarro, M.N.1    Goebel, J.2    Feijoo-Carnero, C.3    Morrice, N.4    Cantrell, D.A.5
  • 16
    • 25844444745 scopus 로고    scopus 로고
    • MSKs are required for the transcription of the nuclear orphan receptors Nur77, Nurr1 and Nor1 downstream of MAPK signalling
    • DOI 10.1042/BJ20050196
    • Darragh, J., Soloaga, A., Beardmore, V. A., Wingate, A. D., Wiggin, G. R., Peggie, M. and Arthur, J. S. (2005) MSKs are required for the transcription of the nuclear orphan receptors Nur77, Nurr1 and Nor1 downstream of MAPK signalling. Biochem. J. 390, 749-759 (Pubitemid 41395358)
    • (2005) Biochemical Journal , vol.390 , Issue.3 , pp. 749-759
    • Darragh, J.1    Soloaga, A.2    Beardmore, V.A.3    Wingate, A.D.4    Wiggin, G.R.5    Reggie, M.6    Arthur, J.S.C.7
  • 18
    • 77951681614 scopus 로고    scopus 로고
    • Generating diversity: Transcriptional regulation of effector and memory CD8 T-cell differentiation
    • Rutishauser, R. L. and Kaech, S. M. (2010) Generating diversity: transcriptional regulation of effector and memory CD8 T-cell differentiation. Immunol. Rev. 235, 219-233
    • (2010) Immunol. Rev. , vol.235 , pp. 219-233
    • Rutishauser, R.L.1    Kaech, S.M.2
  • 20
    • 17144414861 scopus 로고    scopus 로고
    • Protein kinase D1 phosphorylates HDAC7 and induces its nuclear export after T-cell receptor activation
    • DOI 10.1074/jbc.M413396200
    • Parra, M., Kasler, H., McKinsey, T. A., Olson, E. N. and Verdin, E. (2005) Protein kinase D1 phosphorylates HDAC7 and induces its nuclear export after T-cell receptor activation. J. Biol. Chem. 280, 13762-13770 (Pubitemid 40517272)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.14 , pp. 13762-13770
    • Parra, M.1    Kasler, H.2    McKinsey, T.A.3    Olson, E.N.4    Verdin, E.5
  • 21
    • 79954993361 scopus 로고    scopus 로고
    • Histone deacetylase 7 regulates cell survival and TCR signaling in CD4/CD8 double-positive thymocytes
    • Kasler, H. G., Young, B. D., Mottet, D., Lim, H. W., Collins, A. M., Olson, E. N. and Verdin, E. (2011) Histone deacetylase 7 regulates cell survival and TCR signaling in CD4/CD8 double-positive thymocytes. J. Immunol. 186, 4782-4793
    • (2011) J. Immunol. , vol.186 , pp. 4782-4793
    • Kasler, H.G.1    Young, B.D.2    Mottet, D.3    Lim, H.W.4    Collins, A.M.5    Olson, E.N.6    Verdin, E.7
  • 22
    • 34548683483 scopus 로고    scopus 로고
    • + T Cell Differentiation during Viral Infection
    • DOI 10.1016/j.immuni.2007.08.007, PII S1074761307004104
    • Kaech, S. M. and Wherry, E. J. (2007) Heterogeneity and cell-fate decisions in effector and memory CD8+ T cell differentiation during viral infection. Immunity 27, 393-405 (Pubitemid 47418674)
    • (2007) Immunity , vol.27 , Issue.3 , pp. 393-405
    • Kaech, S.M.1    Wherry, E.J.2
  • 24
    • 74549216531 scopus 로고    scopus 로고
    • Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells
    • Pipkin, M. E., Sacks, J. A., Cruz-Guilloty, F., Lichtenheld, M. G., Bevan, M. J. and Rao, A. (2010) Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells. Immunity 32, 79-90
    • (2010) Immunity , vol.32 , pp. 79-90
    • Pipkin, M.E.1    Sacks, J.A.2    Cruz-Guilloty, F.3    Lichtenheld, M.G.4    Bevan, M.J.5    Rao, A.6
  • 26
    • 22344450566 scopus 로고    scopus 로고
    • The timing of TCRα expression critically influences T cell development and selection
    • DOI 10.1084/jem.20050359
    • Baldwin, T. A., Sandau, M. M., Jameson, S. C. and Hogquist, K. A. (2005) The timing of TCRα expression critically influences T cell development and selection. J. Exp. Med. 202, 111-121 (Pubitemid 41002914)
    • (2005) Journal of Experimental Medicine , vol.202 , Issue.1 , pp. 111-121
    • Baldwin, T.A.1    Sandau, M.M.2    Jameson, S.C.3    Hogquist, K.A.4
  • 27
    • 1542373531 scopus 로고    scopus 로고
    • Pre-TCRα and TCRα Are Not Interchangeable Partners of TCRβ during T Lymphocyte Development
    • DOI 10.1084/jem.20031973
    • Borowski, C., Li, X., Aifantis, I., Gounari, F. and von Boehmer, H. (2004) Pre-TCRα and TCRα are not interchangeable partners of TCRβ during T lymphocyte development. J. Exp. Med. 199, 607-615 (Pubitemid 38316428)
    • (2004) Journal of Experimental Medicine , vol.199 , Issue.5 , pp. 607-615
    • Borowski, C.1    Li, X.2    Aifantis, I.3    Gounari, F.4    Von Boehmer, H.5
  • 28
    • 3242695397 scopus 로고    scopus 로고
    • Impact of early expression of TCR α chain on thymocyte development
    • Huang, C. Y. and Kanagawa, O. (2004) Impact of early expression of TCR α chain on thymocyte development. Eur. J. Immunol. 34, 1532-1541
    • (2004) Eur. J. Immunol. , vol.34 , pp. 1532-1541
    • Huang, C.Y.1    Kanagawa, O.2
  • 29
    • 0035284865 scopus 로고    scopus 로고
    • Premature TCRαβ expression and signaling in early thymocytes impair thymocyte expansion and partially block their development
    • Lacorazza, H. D., Tucek-Szabo, C., Vasovic, L. V., Remus, K. and Nikolich-Zugich, J. (2001) Premature TCR αβ expression and signaling in early thymocytes impair thymocyte expansion and partially block their development. J. Immunol. 166, 3184-3193 (Pubitemid 33117316)
    • (2001) Journal of Immunology , vol.166 , Issue.5 , pp. 3184-3193
    • Lacorazza, H.D.1    Tucek-Szabo, C.2    Vasovic, L.V.3    Remus, K.4    Nikolich-Zugich, J.5
  • 30
    • 21844440323 scopus 로고    scopus 로고
    • Unique features of the pre-T-cell receptor α-chain: Not just a surrogate
    • von Boehmer, H. (2005) Unique features of the pre-T-cell receptor α-chain: not just a surrogate. Nat. Rev. Immunol. 5, 571-577
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 571-577
    • Von Boehmer, H.1
  • 32
    • 33845790596 scopus 로고    scopus 로고
    • Molecular basis for pre-TCR-mediated autonomous signaling
    • DOI 10.1016/j.it.2006.11.006, PII S1471490606003280
    • Yamasaki, S. and Saito, T. (2007) Molecular basis for pre-TCR-mediated autonomous signaling. Trends Immunol. 28, 39-43 (Pubitemid 46001618)
    • (2007) Trends in Immunology , vol.28 , Issue.1 , pp. 39-43
    • Yamasaki, S.1    Saito, T.2
  • 33
    • 79961026124 scopus 로고    scopus 로고
    • Protein kinase D: Coupling extracellular stimuli to the regulation of cell physiology
    • Fu, Y. and Rubin, C. S. (2011) Protein kinase D: coupling extracellular stimuli to the regulation of cell physiology. EMBO Rep. 12, 785-796
    • (2011) EMBO Rep. , vol.12 , pp. 785-796
    • Fu, Y.1    Rubin, C.S.2
  • 34
    • 37249016585 scopus 로고    scopus 로고
    • Dimeric PKD regulates membrane fission to form transport carriers at the TGN
    • DOI 10.1083/jcb.200703166
    • Bossard, C., Bresson, D., Polishchuk, R. S. and Malhotra, V. (2007) Dimeric PKD regulates membrane fission to form transport carriers at the TGN. J. Cell Biol. 179, 1123-1131 (Pubitemid 350277732)
    • (2007) Journal of Cell Biology , vol.179 , Issue.6 , pp. 1123-1131
    • Bossard, C.1    Bresson, D.2    Polishchuk, R.S.3    Malhotra, V.4
  • 35
    • 67349096401 scopus 로고    scopus 로고
    • Protein kinase D1 regulates cofilin-mediated F-actin reorganization and cell motility through slingshot
    • Eiseler, T., Doppler, H., Yan, I. K., Kitatani, K., Mizuno, K. and Storz, P. (2009) Protein kinase D1 regulates cofilin-mediated F-actin reorganization and cell motility through slingshot. Nat. Cell Biol. 11, 545-556
    • (2009) Nat. Cell Biol. , vol.11 , pp. 545-556
    • Eiseler, T.1    Doppler, H.2    Yan, I.K.3    Kitatani, K.4    Mizuno, K.5    Storz, P.6
  • 36
    • 1642379541 scopus 로고    scopus 로고
    • Protein Kinase Cδ Selectively Regulates Protein Kinase D-Dependent Activation of NF-κB in Oxidative Stress Signaling
    • DOI 10.1128/MCB.24.7.2614-2626.2004
    • Storz, P., Doppler, H. and Toker, A. (2004) Protein kinase Cδ selectively regulates protein kinase D-dependent activation of NF-κB in oxidative stress signaling. Mol. Cell. Biol. 24, 2614-2626 (Pubitemid 38381256)
    • (2004) Molecular and Cellular Biology , vol.24 , Issue.7 , pp. 2614-2626
    • Storz, P.1    Doppler, H.2    Toker, A.3
  • 37
    • 34249799899 scopus 로고    scopus 로고
    • Genome-wide analysis of gene expression in T cells to identify targets of the NF-κB transcription factor c-Rel
    • Bunting, K., Rao, S., Hardy, K., Woltring, D., Denyer, G. S., Wang, J., Gerondakis, S. and Shannon, M. F. (2007) Genome-wide analysis of gene expression in T cells to identify targets of the NF-κB transcription factor c-Rel. J. Immunol. 178, 7097-7109 (Pubitemid 46847436)
    • (2007) Journal of Immunology , vol.178 , Issue.11 , pp. 7097-7109
    • Bunting, K.1    Rao, S.2    Hardy, K.3    Woltring, D.4    Denyer, G.S.5    Wang, J.6    Gerondalds, S.7    Shannon, M.F.8
  • 39
    • 77953315696 scopus 로고    scopus 로고
    • Protein kinase D controls actin polymerization and cell motility through phosphorylation of cortactin
    • Eiseler, T., Hausser, A., De Kimpe, L., Van Lint, J. and Pfizenmaier, K. (2010) Protein kinase D controls actin polymerization and cell motility through phosphorylation of cortactin. J. Biol. Chem. 285, 18672-18683
    • (2010) J. Biol. Chem. , vol.285 , pp. 18672-18683
    • Eiseler, T.1    Hausser, A.2    De Kimpe, L.3    Van Lint, J.4    Pfizenmaier, K.5
  • 40
    • 79952321053 scopus 로고    scopus 로고
    • A novel protein kinase D phosphorylation site in the tumor suppressor Rab interactor 1 is critical for coordination of cell migration
    • Ziegler, S., Eiseler, T., Scholz, R. P., Beck, A., Link, G. and Hausser, A. (2011) A novel protein kinase D phosphorylation site in the tumor suppressor Rab interactor 1 is critical for coordination of cell migration. Mol. Biol. Cell 22, 570-580
    • (2011) Mol. Biol. Cell , vol.22 , pp. 570-580
    • Ziegler, S.1    Eiseler, T.2    Scholz, R.P.3    Beck, A.4    Link, G.5    Hausser, A.6
  • 43
    • 78049284317 scopus 로고    scopus 로고
    • Protein kinase D1 suppresses epithelial-to-mesenchymal transition through phosphorylation of snail
    • Du, C., Zhang, C., Hassan, S., Biswas, M. H. and Balaji, K. C. (2010) Protein kinase D1 suppresses epithelial-to-mesenchymal transition through phosphorylation of snail. Cancer Res. 70, 7810-7819
    • (2010) Cancer Res. , vol.70 , pp. 7810-7819
    • Du, C.1    Zhang, C.2    Hassan, S.3    Biswas, M.H.4    Balaji, K.C.5
  • 44
    • 67549112510 scopus 로고    scopus 로고
    • Protein kinase D1 regulates matrix metalloproteinase expression and inhibits breast cancer cell invasion
    • Eiseler, T., Doppler, H., Yan, I. K., Goodison, S. and Storz, P. (2009) Protein kinase D1 regulates matrix metalloproteinase expression and inhibits breast cancer cell invasion. Breast Cancer Res. 11, R13
    • (2009) Breast Cancer Res. , vol.11
    • Eiseler, T.1    Doppler, H.2    Yan, I.K.3    Goodison, S.4    Storz, P.5


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