Proteomic profiling of H-Ras-G12V induced hypertrophic cardiomyopathy in transgenic mice using comparative LC-MS analysis of thin fresh-frozen tissue sections

Journal of Proteome Research

Volumn 11, Issue 3, 2012, Pages 1561-1570

  Wei, Bih Rong ^a   Simpson, R Mark ^a   Johann, Donald J ^a   Dwyer, Jennifer E ^a   Prieto, Darue A ^b   Kumar, Mia ^a   Ye, Xiaoying ^b   Luke, Brian ^b   Shive, Heather R ^a   Webster, Joshua D ^a   Hoover, Shelley B ^a   Veenstra, Timothy D ^b   Blonder, Josip ^b  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

comparative proteomic profiling; fresh frozen tissue; H Ras; hypertrophic cardiomyopathy; methanol based solubilization digestion; method development; pathway analysis

Indexed keywords

BETA CATENIN; GLYCOGEN SYNTHASE KINASE 3BETA; H RAS PROTEIN; METHANOL; PHOSPHOPROTEIN; RAS PROTEIN; UNCLASSIFIED DRUG; WNT3A PROTEIN;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CONFERENCE PAPER; CONTROLLED STUDY; HEART MUSCLE; HYPERTROPHIC CARDIOMYOPATHY; IMMUNOHISTOCHEMISTRY; ION CYCLOTRON RESONANCE MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEOMICS; SOLUBILIZATION; TISSUE SECTION; TRANSGENIC MOUSE; WESTERN BLOTTING; WILD TYPE;

AMINO ACID SEQUENCE; ANIMALS; BETA CATENIN; CARDIOMYOPATHY, HYPERTROPHIC; CHROMATOGRAPHY, LIQUID; CLUSTER ANALYSIS; GENE EXPRESSION; GENE EXPRESSION REGULATION; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; MYOCARDIUM; PEPTIDE FRAGMENTS; PROTEIN PRECURSORS; PROTEOME; PROTEOMICS; PROTO-ONCOGENE PROTEINS P21(RAS); VIMENTIN; WNT3A PROTEIN;

MUS MUSCULUS;

EID: 84857851005     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr200612y     Document Type: Conference Paper

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