메뉴 건너뛰기




Volumn 129, Issue 3, 2012, Pages 367-370

Thrombin generation in clinical conditions

Author keywords

Arterial thrombosis atherosclerosis; Bleeding; Thrombin generation; Venous thromboembolism

Indexed keywords

ACTIVATED PROTEIN C; THROMBIN; THROMBOMODULIN;

EID: 84857789282     PISSN: 00493848     EISSN: 18792472     Source Type: Journal    
DOI: 10.1016/j.thromres.2011.10.017     Document Type: Review
Times cited : (82)

References (50)
  • 1
    • 0344630172 scopus 로고    scopus 로고
    • The blood coagulation system as a molecular machine
    • DOI 10.1002/bies.10360
    • H.M. Spronk, J.W. Govers-Riemslag, and H. ten Cate The blood coagulation system as a molecular machine Bioessays 25 12 2003 Dec 1220 1228 (Pubitemid 37499322)
    • (2003) BioEssays , vol.25 , Issue.12 , pp. 1220-1228
    • Spronk, H.M.H.1    Govers-Riemslag, J.W.P.2    Ten Cate, H.3
  • 2
    • 66249141983 scopus 로고    scopus 로고
    • Is thrombin a key player in the 'coagulation-atherogenesis' maze?
    • J.I. Borissoff, H.M. Spronk, S. Heeneman, and H. ten Cate Is thrombin a key player in the 'coagulation-atherogenesis' maze? Cardiovasc Res 82 3 2009 Jun 1 392 403
    • (2009) Cardiovasc Res , vol.82 , Issue.3 , pp. 392-403
    • Borissoff, J.I.1    Spronk, H.M.2    Heeneman, S.3    Ten Cate, H.4
  • 3
    • 38349170097 scopus 로고    scopus 로고
    • Recollections on thrombin generation
    • H.C. Hemker Recollections on thrombin generation J Thromb Haemost 6 2 2008 Feb 219 226
    • (2008) J Thromb Haemost , vol.6 , Issue.2 , pp. 219-226
    • Hemker, H.C.1
  • 4
    • 0023261782 scopus 로고
    • The pathophysiology of the prethrombotic state in humans: Insights gained from studies using markers of hemostatic system activation
    • K.A. Bauer, and R.D. Rosenberg The pathophysiology of the prethrombotic state in humans: insights gained from studies using markers of hemostatic system activation Blood 70 2 1987 343 350 (Pubitemid 17142912)
    • (1987) Blood , vol.70 , Issue.2 , pp. 343-350
    • Bauer, K.A.1    Rosenberg, R.D.2
  • 6
    • 50049135947 scopus 로고    scopus 로고
    • Thrombin generation testing in routine clinical practice: Are we there yet?
    • J.J. van Veen, A. Gatt, and M. Makris Thrombin generation testing in routine clinical practice: are we there yet? Br J Haematol 142 6 2008 Sep 889 903
    • (2008) Br J Haematol , vol.142 , Issue.6 , pp. 889-903
    • Van Veen, J.J.1    Gatt, A.2    Makris, M.3
  • 7
    • 79251495773 scopus 로고    scopus 로고
    • Thrombin generation tests
    • E. Castoldi, and J. Rosing Thrombin generation tests Thromb Res 127 Suppl 3 2011 Feb S21 S25
    • (2011) Thromb Res , vol.127 , Issue.SUPPL. 3
    • Castoldi, E.1    Rosing, J.2
  • 8
    • 74249121899 scopus 로고    scopus 로고
    • Thrombin generation as an intermediate phenotype for venous thrombosis
    • O. Segers, R. van Oerle, H. ten Cate, J. Rosing, and E. Castoldi Thrombin generation as an intermediate phenotype for venous thrombosis Thromb Haemost 103 1 2010 Jan 114 122
    • (2010) Thromb Haemost , vol.103 , Issue.1 , pp. 114-122
    • Segers, O.1    Van Oerle, R.2    Ten Cate, H.3    Rosing, J.4    Castoldi, E.5
  • 9
    • 70350007969 scopus 로고    scopus 로고
    • Peak thrombin generation and subsequent venous thromboembolism: The Longitudinal Investigation of Thromboembolism Etiology (LITE) study
    • P.L. Lutsey, A.R. Folsom, S.R. Heckbert, and M. Cushman Peak thrombin generation and subsequent venous thromboembolism: the Longitudinal Investigation of Thromboembolism Etiology (LITE) study J Thromb Haemost 7 10 2009 Oct 1639 1648
    • (2009) J Thromb Haemost , vol.7 , Issue.10 , pp. 1639-1648
    • Lutsey, P.L.1    Folsom, A.R.2    Heckbert, S.R.3    Cushman, M.4
  • 11
    • 78651348333 scopus 로고    scopus 로고
    • A thrombin generation assay may reduce the need for compression ultrasonography for the exclusion of deep venous thrombosis in the elderly
    • F.J. Haas, R.E. Schutgens, C. Kluft, and D.H. Biesma A thrombin generation assay may reduce the need for compression ultrasonography for the exclusion of deep venous thrombosis in the elderly Scand J Clin Lab Invest 71 1 2011 Feb 12 18
    • (2011) Scand J Clin Lab Invest , vol.71 , Issue.1 , pp. 12-18
    • Haas, F.J.1    Schutgens, R.E.2    Kluft, C.3    Biesma, D.H.4
  • 12
    • 33746453363 scopus 로고    scopus 로고
    • Identification of patients at low risk for recurrent venous thromboembolism by measuring thrombin generation
    • DOI 10.1001/jama.296.4.397
    • G. Hron, M. Kollars, B.R. Binder, S. Eichinger, and P.A. Kyrle Identification of patients at low risk for recurrent venous thromboembolism by measuring thrombin generation JAMA 296 4 2006 Jul 26 397 402 (Pubitemid 44127523)
    • (2006) Journal of the American Medical Association , vol.296 , Issue.4 , pp. 397-402
    • Hron, G.1    Kollars, M.2    Binder, B.R.3    Eichinger, S.4    Kyrle, P.A.5
  • 13
    • 47649111844 scopus 로고    scopus 로고
    • High thrombin generation measured in the presence of thrombomodulin is associated with an increased risk of recurrent venous thromboembolism
    • DOI 10.1111/j.1538-7836.2008.03018.x
    • A. Tripodi, C. Legnani, V. Chantarangkul, B. Cosmi, G. Palareti, and P.M. Mannucci High thrombin generation measured in the presence of thrombomodulin is associated with an increased risk of recurrent venous thromboembolism J Thromb Haemost 6 8 2008 Aug 1327 1333 (Pubitemid 352016312)
    • (2008) Journal of Thrombosis and Haemostasis , vol.6 , Issue.8 , pp. 1327-1333
    • Tripodi, A.1    Legnani, C.2    Chantarangkul, V.3    Cosmi, B.4    Palareti, G.5    Mannucci, P.M.6
  • 14
    • 52449104894 scopus 로고    scopus 로고
    • High rate of unprovoked recurrent venous thrombosis is associated with high thrombin-generating potential in a prospective cohort study
    • Epub 2008 Aug 1
    • M. Besser, C. Baglin, R. Luddington, A. van Hylckama Vlieg, and T. Baglin High rate of unprovoked recurrent venous thrombosis is associated with high thrombin-generating potential in a prospective cohort study J Thromb Haemost 6 10 2008 Oct 1720 1725 Epub 2008 Aug 1.
    • (2008) J Thromb Haemost , vol.6 , Issue.10 , pp. 1720-1725
    • Besser, M.1    Baglin, C.2    Luddington, R.3    Van Hylckama Vlieg, A.4    Baglin, T.5
  • 15
    • 34548155406 scopus 로고    scopus 로고
    • Elevated endogenous thrombin potential is associated with an increased risk of a first deep venous thrombosis but not with the risk of recurrence
    • DOI 10.1111/j.1365-2141.2007.06738.x
    • A. van Hylckama Vlieg, S.C. Christiansen, R. Luddington, S.C. Cannegieter, F.R. Rosendaal, and T.P. Baglin Elevated endogenous thrombin potential is associated with an increased risk of a first deep venous thrombosis but not with the risk of recurrence Br J Haematol 138 6 2007 Sep 769 774 (Pubitemid 47313221)
    • (2007) British Journal of Haematology , vol.138 , Issue.6 , pp. 769-774
    • Van Hylckama Vlieg, A.1    Christiansen, S.C.2    Luddington, R.3    Cannegieter, S.C.4    Rosendaal, F.R.5    Baglin, T.P.6
  • 17
    • 79957517025 scopus 로고    scopus 로고
    • Prediction of venous thromboembolism in patients with cancer by measuring thrombin generation: Results from the Vienna Cancer and Thrombosis Study
    • C. Ay, D. Dunkler, R. Simanek, J. Thaler, S. Koder, and C. Marosi Prediction of venous thromboembolism in patients with cancer by measuring thrombin generation: results from the Vienna Cancer and Thrombosis Study J Clin Oncol 29 15 2011 May 20 2099 2103
    • (2011) J Clin Oncol , vol.29 , Issue.15 , pp. 2099-2103
    • Ay, C.1    Dunkler, D.2    Simanek, R.3    Thaler, J.4    Koder, S.5    Marosi, C.6
  • 18
    • 79955787524 scopus 로고    scopus 로고
    • An activated protein C-dependent thrombin generation assay predicts chemotherapy-associated venous thromboembolism in cancer patients
    • P. Ferroni, F. Martini, I. Portarena, I. Grenga, S. Riondino, and F. La Farina An activated protein C-dependent thrombin generation assay predicts chemotherapy-associated venous thromboembolism in cancer patients Thromb Haemost 105 5 2011 May 931 932
    • (2011) Thromb Haemost , vol.105 , Issue.5 , pp. 931-932
    • Ferroni, P.1    Martini, F.2    Portarena, I.3    Grenga, I.4    Riondino, S.5    La Farina, F.6
  • 19
    • 58149145904 scopus 로고    scopus 로고
    • Thrombin generation and activated protein C resistance in patients with essential thrombocythemia and polycythemia vera
    • M. Marchetti, E. Castoldi, H.M. Spronk, R. van Oerle, D. Balducci, and T. Barbui Thrombin generation and activated protein C resistance in patients with essential thrombocythemia and polycythemia vera Blood 112 10 2008 Nov 15 4061 4068
    • (2008) Blood , vol.112 , Issue.10 , pp. 4061-4068
    • Marchetti, M.1    Castoldi, E.2    Spronk, H.M.3    Van Oerle, R.4    Balducci, D.5    Barbui, T.6
  • 20
    • 79953031063 scopus 로고    scopus 로고
    • Platelet-induced thrombin generation by the calibrated automated thrombogram assay is increased in patients with essential thrombocythemia and polycythemia vera
    • M. Panova-Noeva, M. Marchetti, H.M. Spronk, L. Russo, E. Diani, and G. Finazzi Platelet-induced thrombin generation by the calibrated automated thrombogram assay is increased in patients with essential thrombocythemia and polycythemia vera Am J Hematol 86 4 2011 Apr 337 342
    • (2011) Am J Hematol , vol.86 , Issue.4 , pp. 337-342
    • Panova-Noeva, M.1    Marchetti, M.2    Spronk, H.M.3    Russo, L.4    Diani, E.5    Finazzi, G.6
  • 21
    • 67650727986 scopus 로고    scopus 로고
    • Elevated procoagulant microparticles expressing endothelial and platelet markers in essential thrombocythemia
    • M.C. Trappenburg, M. van Schilfgaarde, M. Marchetti, H.M. Spronk, H. ten Cate, and A. Leyte Elevated procoagulant microparticles expressing endothelial and platelet markers in essential thrombocythemia Haematologica 94 7 2009 Jul 911 918
    • (2009) Haematologica , vol.94 , Issue.7 , pp. 911-918
    • Trappenburg, M.C.1    Van Schilfgaarde, M.2    Marchetti, M.3    Spronk, H.M.4    Ten Cate, H.5    Leyte, A.6
  • 22
    • 33344478392 scopus 로고    scopus 로고
    • Seven haemostatic gene polymorphisms in coronary disease: Meta-analysis of 66 155 cases and 91 307 controls
    • DOI 10.1016/S0140-6736(06)68263-9, PII S0140673606682639
    • Z. Ye, E.H. Liu, J.P. Higgins, B.D. Keavney, G.D. Lowe, and R. Collins Seven haemostatic gene polymorphisms in coronary disease: meta-analysis of 66,155 cases and 91,307 controls Lancet 367 9511 2006 Feb 25 651 658 (Pubitemid 43289155)
    • (2006) Lancet , vol.367 , Issue.9511 , pp. 651-658
    • Ye, Z.1    Liu, E.H.2    Higgins, J.P.3    Keavney, B.D.4    Lowe, G.D.5    Collins, R.6    Danesh, J.7
  • 23
    • 79955706734 scopus 로고    scopus 로고
    • The hemostatic system as a modulator of atherosclerosis
    • J.I. Borissoff, H.M. Spronk, and H. ten Cate The hemostatic system as a modulator of atherosclerosis N Engl J Med 364 18 2011 May 5 1746 1760
    • (2011) N Engl J Med , vol.364 , Issue.18 , pp. 1746-1760
    • Borissoff, J.I.1    Spronk, H.M.2    Ten Cate, H.3
  • 24
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis - An inflammatory disease
    • DOI 10.1056/NEJM199901143400207
    • R. Ross Atherosclerosis - an inflammatory disease N Engl J Med 340 2 1999 Jan 115 126 Review. (Pubitemid 29054847)
    • (1999) New England Journal of Medicine , vol.340 , Issue.2 , pp. 115-126
    • Ross, R.1
  • 27
    • 79951723277 scopus 로고    scopus 로고
    • Hypercoagulability in patients with type 2 diabetes mellitus detected by a thrombin generation assay
    • A. Tripodi, A. Branchi, V. Chantarangkul, M. Clerici, G. Merati, and A. Artoni Hypercoagulability in patients with type 2 diabetes mellitus detected by a thrombin generation assay J Thromb Thrombolysis 31 2 2011 Feb 165 172
    • (2011) J Thromb Thrombolysis , vol.31 , Issue.2 , pp. 165-172
    • Tripodi, A.1    Branchi, A.2    Chantarangkul, V.3    Clerici, M.4    Merati, G.5    Artoni, A.6
  • 28
    • 77957714048 scopus 로고    scopus 로고
    • Haemostatic alterations in overweight children: Associations between metabolic syndrome, thrombin generation, and fibrinogen levels
    • Epub 2010 Jun 2
    • P. Fritsch, M. Kleber, A. Rosenkranz, M. Fritsch, W. Muntean, and H. Mangge Haemostatic alterations in overweight children: associations between metabolic syndrome, thrombin generation, and fibrinogen levels Atherosclerosis 212 2 2010 Oct 650 655 Epub 2010 Jun 2
    • (2010) Atherosclerosis , vol.212 , Issue.2 , pp. 650-655
    • Fritsch, P.1    Kleber, M.2    Rosenkranz, A.3    Fritsch, M.4    Muntean, W.5    Mangge, H.6
  • 29
    • 80053346660 scopus 로고    scopus 로고
    • Thrombin generation in chronic obstructive pulmonary disease: Dependence on plasma clotting factor composition. et al
    • May 28 (epub ahead of print))
    • A. Undas, M. Jankowski, P. Kaczmarek, K. Sladek, and K. Brummel-Ziedins Thrombin generation in chronic obstructive pulmonary disease: dependence on plasma clotting factor composition. et al Thromb Res 2011 May 28 (epub ahead of print))
    • (2011) Thromb Res
    • Undas, A.1    Jankowski, M.2    Kaczmarek, P.3    Sladek, K.4    Brummel-Ziedins, K.5
  • 31
  • 32
    • 79957517864 scopus 로고    scopus 로고
    • Increased thrombin generation is associated with acute ischemic stroke but not with coronary heart disease in the elderly: The Three-City cohort study
    • Epub 2011 Mar 31
    • L. Carcaillon, M. Alhenc-Gelas, Y. Bejot, C. Spaft, P. Ducimetière, and K. Ritchie Increased thrombin generation is associated with acute ischemic stroke but not with coronary heart disease in the elderly: the Three-City cohort study Arterioscler Thromb Vasc Biol 31 6 2011 Jun 1445 1451 Epub 2011 Mar 31.
    • (2011) Arterioscler Thromb Vasc Biol , vol.31 , Issue.6 , pp. 1445-1451
    • Carcaillon, L.1    Alhenc-Gelas, M.2    Bejot, Y.3    Spaft, C.4    Ducimetière, P.5    Ritchie, K.6
  • 35
    • 2142718287 scopus 로고    scopus 로고
    • Prothrombin fragment 1+2 is associated with carotid intima-media thickness in subjects free of clinical cardiovascular disease
    • DOI 10.1161/01.STR.0000124927.38723.f2
    • J.A. Páramo, J. Orbe, O. Beloqui, A. Benito, I. Colina, and E. Martinez-Vila Prothrombin fragment 1+2 is associated with carotid intima-media thickness in subjects free of clinical cardiovascular disease Stroke 35 5 2004 May 1085 1089 (Pubitemid 38543522)
    • (2004) Stroke , vol.35 , Issue.5 , pp. 1085-1089
    • Paramo, J.A.1    Orbe, J.2    Beloqui, O.3    Benito, A.4    Colina, I.5    Martinez-Vila, E.6    Diez, J.7
  • 36
    • 79952114897 scopus 로고    scopus 로고
    • Relationship between thrombin generation and carotid intima-media thickness
    • H. Bernhard, P. Wipfler, B. Leschnik, M. Novak, J. Kraus, and G. Pilz Relationship between thrombin generation and carotid intima-media thickness Hamostaseologie 30 Suppl 1 2010 Nov S168 S171
    • (2010) Hamostaseologie , vol.30 , Issue.SUPPL. 1
    • Bernhard, H.1    Wipfler, P.2    Leschnik, B.3    Novak, M.4    Kraus, J.5    Pilz, G.6
  • 39
    • 38949100506 scopus 로고    scopus 로고
    • Increased thrombin generation after acute versus chronic coronary disease as assessed by the thrombin generation test
    • DOI 10.1160/TH07-07-0443
    • J. Orbe, M. Zudaire, R. Serrano, I. Coma-Canella, S. Martínez de Sizarrondo, and J.A. Rodríguez Increased thrombin generation after acute versus chronic coronary disease as assessed by the thrombin generation test Thromb Haemost 99 2 2008 Feb 382 387 (Pubitemid 351230970)
    • (2008) Thrombosis and Haemostasis , vol.99 , Issue.2 , pp. 382-387
    • Orbe, J.1    Zudaire, M.2    Serrano, R.3    Coma-Canella, I.4    De Sizarrondo, S.M.5    Rodriguez, J.A.6    Paramo, J.A.7
  • 41
    • 37549018513 scopus 로고    scopus 로고
    • Thrombin generation in acute coronary syndrome and stable coronary artery disease: Dependence on plasma factor composition
    • K. Brummel-Ziedins, A. Undas, T. Orfeo, M. Gissel, S. Butenas, and K. Zmudka Thrombin generation in acute coronary syndrome and stable coronary artery disease: dependence on plasma factor composition J Thromb Haemost 6 1 2008 Jan 104 110
    • (2008) J Thromb Haemost , vol.6 , Issue.1 , pp. 104-110
    • Brummel-Ziedins, K.1    Undas, A.2    Orfeo, T.3    Gissel, M.4    Butenas, S.5    Zmudka, K.6
  • 42
    • 70149095695 scopus 로고    scopus 로고
    • Thrombin activity throughout the acute phase of acute ST-elevation myocardial infarction and the relation to outcome
    • N.V. Ulrich-Möckel, M. Riehle, J. Vollert, G. Heller Jr., T. Störk, and H. Riess Thrombin activity throughout the acute phase of acute ST-elevation myocardial infarction and the relation to outcome Biomarkers 14 5 2009 Aug 311 316
    • (2009) Biomarkers , vol.14 , Issue.5 , pp. 311-316
    • Ulrich-Möckel, N.V.1    Riehle, M.2    Vollert, J.3    Heller, Jr.G.4    Störk, T.5    Riess, H.6
  • 45
    • 77955015786 scopus 로고    scopus 로고
    • Test of global haemostasis and their applications in bleeding disorders
    • S.C. Nair, Y. Dargaud, M. Chitlur, and A. Srivastava Test of global haemostasis and their applications in bleeding disorders Haemophilia 16 Suppl 5 2010 85 92
    • (2010) Haemophilia , vol.16 , Issue.SUPPL. 5 , pp. 85-92
    • Nair, S.C.1    Dargaud, Y.2    Chitlur, M.3    Srivastava, A.4
  • 46
    • 80052368312 scopus 로고    scopus 로고
    • Thrombin generation inpatients with a bleeding tendency of unknown origin
    • [Epub ahead of print] PubMed PMID: 21359651
    • C. Ay, J. Haselböck, C. Laczkovics, S. Koder, and I. Pabinger Thrombin generation inpatients with a bleeding tendency of unknown origin Ann Hematol 26 2011 Feb [Epub ahead of print] PubMed PMID: 21359651.
    • (2011) Ann Hematol , vol.26
    • Ay, C.1    Haselböck, J.2    Laczkovics, C.3    Koder, S.4    Pabinger, I.5
  • 47
    • 78650492660 scopus 로고    scopus 로고
    • Prospective assessment of thrombin generation test for dose monitoring of bypassing therapy in hemophilia patients with inhibitors undergoing elective surgery
    • Y. Dargaud, A. Lienhart, and C. Negrier Prospective assessment of thrombin generation test for dose monitoring of bypassing therapy in hemophilia patients with inhibitors undergoing elective surgery Blood 116 25 2010 Dec 16 5734 5737
    • (2010) Blood , vol.116 , Issue.25 , pp. 5734-5737
    • Dargaud, Y.1    Lienhart, A.2    Negrier, C.3
  • 48
    • 80051579334 scopus 로고    scopus 로고
    • Thrombin generation assay using factor IXa as a trigger to quantify accurately factor VIII levels in haemophilia A
    • May 23 (epub ahead if print)
    • M. Ninivaggi, Y. Dargaud, R. van Oerle, B. de Laat, H.C. Hemker, and T. Lindhout Thrombin generation assay using factor IXa as a trigger to quantify accurately factor VIII levels in haemophilia A J Thromb Haemost 2011 May 23 (epub ahead if print)
    • (2011) J Thromb Haemost
    • Ninivaggi, M.1    Dargaud, Y.2    Van Oerle, R.3    De Laat, B.4    Hemker, H.C.5    Lindhout, T.6
  • 49
    • 84857985180 scopus 로고    scopus 로고
    • Evaluation of the overall haemostatic effect of recombinant factor VIIa by measuring thrombin generation and stability of fibrin clots
    • 10.1111/j.1365-2516.2011.02526.x [Epub ahead of print]
    • Y. Dargaud, C. Prevost, A. Lienhart, J. Claude Bordet, and C. Negrier Evaluation of the overall haemostatic effect of recombinant factor VIIa by measuring thrombin generation and stability of fibrin clots Haemophilia 2011 Apr 1 10.1111/j.1365-2516.2011.02526.x [Epub ahead of print]
    • (2011) Haemophilia
    • Dargaud, Y.1    Prevost, C.2    Lienhart, A.3    Claude Bordet, J.4    Negrier, C.5
  • 50
    • 75749148413 scopus 로고    scopus 로고
    • Impaired thrombin generation and fibrin clot formation in patients with dilutional coagulopathy during major surgery
    • S.E. Schols, M.D. Lancé, M.A. Feijge, J. Damoiseaux, M.A. Marcus, and K. Hamulyák Impaired thrombin generation and fibrin clot formation in patients with dilutional coagulopathy during major surgery Thromb Haemost 103 2 2010 Feb 318 328
    • (2010) Thromb Haemost , vol.103 , Issue.2 , pp. 318-328
    • Schols, S.E.1    Lancé, M.D.2    Feijge, M.A.3    Damoiseaux, J.4    Marcus, M.A.5    Hamulyák, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.