Thrombin generation assay using factor IXa as a trigger to quantify accurately factor VIII levels in haemophilia A

Journal of Thrombosis and Haemostasis

Volumn 9, Issue 8, 2011, Pages 1549-1555

  Ninivaggi, M ^a,b   Dargaud, Y ^c   van Oerle, R ^d   de Laat, B ^e,f   Hemker, H C ^a,b   Lindhout, Theo ^a,b  

^a Synapse BV   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

^c EDOUARD HERRIOT HOSPITAL   (France)

^d MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^e UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^f SANQUIN RESEARCH   (Netherlands)

Author keywords

Factor IXa driven thrombin generation; FVIII assay; Hemophilia A

Indexed keywords

BLOOD CLOTTING FACTOR 8; BLOOD CLOTTING FACTOR 9A; THROMBIN;

ADULT; AGED; ARTICLE; ASSAY; CALIBRATED AUTOMATED THROMBIN GENERATION ASSAY; CLINICAL ARTICLE; DIAGNOSTIC ACCURACY; GENETIC DISORDER; GENETIC HETEROGENEITY; HEMOPHILIA A; HUMAN; LABORATORY TEST; PHENOTYPE; PRIORITY JOURNAL; THROMBIN TIME;

ADULT; AGED; BIOLOGICAL MARKERS; BLOOD COAGULATION TESTS; FACTOR VIII; FACTOR XA; FRANCE; HEMOPHILIA A; HUMANS; KINETICS; MIDDLE AGED; NETHERLANDS; PHENOTYPE; PREDICTIVE VALUE OF TESTS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SEVERITY OF ILLNESS INDEX; THROMBIN; THROMBOPLASTIN; YOUNG ADULT;

EID: 80051579334     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2011.04358.x     Document Type: Article

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