Hypercoagulability in patients with type 2 diabetes mellitus detected by a thrombin generation assay

Journal of Thrombosis and Thrombolysis

Volumn 31, Issue 2, 2011, Pages 165-172

  Tripodi, Armando ^a   Branchi, Adriana ^a   Chantarangkul, Veena ^a   Clerici, Marigrazia ^a   Merati, Giuliana ^a   Artoni, Andrea ^a   Mannucci, Pier Mannuccio ^a  

^a UNIVERSITY OF MILAN   (Italy)

Author keywords

Anti coagulant factors; Pro coagulant factors; Thrombin generation; Thrombomodulin; Thrombosis

Indexed keywords

INSULIN; ORAL ANTIDIABETIC AGENT; THROMBIN;

ADULT; AGED; ANTICOAGULATION; ARTICLE; BLOOD CLOTTING TEST; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DIET THERAPY; FEMALE; HUMAN; HYPERCOAGULABILITY; MAJOR CLINICAL STUDY; MALE; MEMBRANE MICROPARTICLE; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; RISK FACTOR; THROMBIN TIME;

ADULT; AGED; BLOOD COAGULATION TESTS; CELL-DERIVED MICROPARTICLES; DIABETES COMPLICATIONS; DIABETES MELLITUS, TYPE 2; FEMALE; HUMANS; MIDDLE AGED; RISK FACTORS; THROMBIN; THROMBOPHILIA; VENOUS THROMBOEMBOLISM;

EID: 79951723277     PISSN: 09295305     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11239-010-0506-0     Document Type: Article

References (34)

1. E Adeghate P Schattner E Dunn 2006 An update on the etiology and epidemiology of diabetes mellitus Ann N Y Acad Sci 1084 1 29 10.1196/annals.1372.029 17151290 (Pubitemid 47091962)
2. S Coccheri 2007 Approaches to prevention of cardiovascular complications and events in diabetes mellitus Drugs 67 997 1026 1:CAS:528:DC%2BD2sXnt1Srsb8%3D 10.2165/00003495-200767070-00005 17488145 (Pubitemid 46744476)
3. V Petrauskiene M Falk I Waernbaum M Norberg JW Eriksson 2005 The risk of venous thromboembolism is markedly elevated in patients with diabetes Diabetologia 48 1017 1021 1:STN:280:DC%2BD2M3ltFaksw%3D%3D 10.1007/s00125-005- 1715-5 15778859 (Pubitemid 40767997)
4. CR Keenan S Murin RH White 2007 High risk for venous thromboembolism in diabetics with hyperosmolar state: comparison with other acute medical illnesses Thromb Haemost 5 1185 1190 1:STN:280:DC%2BD2szntVWqtA%3D%3D 10.1111/j.1538-7836.2007.02553.x (Pubitemid 46902120)
5. PD Stein J Goldman F Matta AY Yaekoub 2009 Diabetes mellitus and risk of venous thromboembolism Am J Med Sci 337 259 264 10.1097/MAJ.0b013e31818bbb8b 19365171
6. JA Heit CL Leibson AA Ashrani TM Petterson KR Bailey LJ Melton III 2009 Is diabetes mellitus an independent risk factor for venous thromboembolism? a population-based case-control study Arterioscler Thromb Vasc Biol 29 1399 1405 1:CAS:528:DC%2BD1MXpsFykt7c%3D 10.1161/ATVBAHA.109.189290 19542020
7. A Ceriello 1997 Fibrinogen and diabetes mellitus: is it time for intervention trials? Diabetologia 40 731 734 1:STN:280:DyaK2szmsFyhug%3D%3D 10.1007/s001250050741 9222655 (Pubitemid 27288121)
8. DW Sommeijer HR Hansen R van Oerle K Hamulyak AP van Zanten E Meesters HM Spronk H ten Cate 2006 Soluble tissue factor is a candidate marker for progression of microvascular disease in patients with type 2 diabetes J Thromb Haemost 4 574 580 1:CAS:528:DC%2BD28XjtFejs7w%3D 10.1111/j.1538-7836.2005.01763. x 16371118
9. DL Sauls AE Banini LC Boyd M Hoffman 2007 Elevated prothrombin level and shortened clotting times in subjects with type 2 diabetes J Thromb Haemost 5 638 639 1:CAS:528:DC%2BD2sXktFCis74%3D 10.1111/j.1538-7836.2007.02366.x 17166250 (Pubitemid 46680712)
10. A Ceriello A Quatraro P Dello Russo E Marchi M Barbanti MR Milani D Giugliano 1990 Protein C deficiency in insulin-dependent diabetes: a hyperglycemia-related phenomenon Thromb Haemost 64 104 107 1:STN:280: DyaK3M7htFejtQ%3D%3D 2274914 (Pubitemid 20301859)
11. A Ceriello A Quatraro E Marchi M Barbanti P Dello Russo P Lefebvre D Giugliano 1990 The role of hyperglycaemia-induced alterations of antithrombin III and factor X activation in the thrombin hyperactivity of diabetes mellitus Diabet Med 7 343 348 1:STN:280:DyaK3c3kvFajuw%3D%3D 10.1111/j.1464-5491.1990. tb01402.x 2140088 (Pubitemid 20145984)
12. HC Hemker P Giesen R Al Dieri V Regnault E de Smedt R Wagenvoord T Lecompte S Béguin 2003 Calibrated automated thrombin generation measurement in clotting plasma Pathophysiol Haemost Thromb 33 4 15 1:CAS:528:DC%2BD3sXltlChurs%3D 10.1159/000071636 12853707 (Pubitemid 37449290)
13. V Chantarangkul M Clerici A Bressi PL Giesen A Tripodi 2003 Thrombin generation assessed as endogenous thrombin potential (ETP) in patients with hypo- or hyper-coagulability. Effects of phospholipids, tissue factor and residual platelets on the measurement performed in platelet-poor and platelet-rich plasma Haematologica 88 547 554 1:CAS:528:DC%2BD3sXlslCjurs%3D 12745274
14. AS Shet O Aras K Gupta MJ Hass DJ Rausch N Saba L Koopmeiners NS Key RP Hebbel 2003 Sickle blood contains tissue factor-positive microparticles derived from endothelial cells and monocytes Blood 102 2678 2683 1:CAS:528: DC%2BD3sXnslyku7k%3D 10.1182/blood-2003-03-0693 12805058 (Pubitemid 37193612)
15. P Prandoni 2007 Links between arterial and venous disease J Intern Med 262 341 350 1:STN:280:DC%2BD2svotV2jug%3D%3D 10.1111/j.1365-2796.2007.01815.x 17697155 (Pubitemid 47246969)
16. V Ageno C Becattini T Brighton R Selby PW Kamphuisen 2008 Cardiovascular risk factors and venous thromboembolism. A meta-analysis Circulation 117 93 102 10.1161/CIRCULATIONAHA.107.709204 18086925 (Pubitemid 350301144)
17. A Tripodi V Chantarangkul PM Mannucci 2009 Acquired coagulation disorders: revisited using global coagulation/anticoagulation testing Br J Haematol 147 77 82 10.1111/j.1365-2141.2009.07833.x 19659548
18. A van Hylckama Vlieg SC Christiansen R Luddington SC Cannegieter FR Rosendaal TP Baglin 2007 Elevated endogenous thrombin potential is associated with an increased risk of a first deep venous thrombosis but not with the risk of recurrence Br J Haematol 138 769 774 10.1111/j.1365-2141.2007.06738.x 17760809 (Pubitemid 47313221)
19. G Hron M Kollars BR Binder S Eichinger PA Kyrle 2006 Identification of patients at low risk for recurrent venous thromboembolism by measuring thrombin generation JAMA 296 397 402 1:CAS:528:DC%2BD28Xntlamt7s%3D 10.1001/jama.296.4. 397 16868297 (Pubitemid 44127523)
20. A Tripodi C Legnani V Chantarangkul B Cosmi G Palareti PM Mannucci 2008 High thrombin generation measured in the presence of thrombomodulin is associated with an increased risk of recurrent venous thromboembolism J Thromb Haemost 6 1327 1333 1:CAS:528:DC%2BD1cXhtVOgtb%2FF 10.1111/j.1538-7836.2008. 03018.x 18485081 (Pubitemid 352016312)
21. M Besser C Baglin R Luddington A van Hylckama Vlieg T Baglin 2008 High rate of unprovoked recurrent venous thrombosis is associated with high thrombin-generating potential in a prospective cohort study J Thromb Haemost 6 1720 1725 1:STN:280:DC%2BD1cnks1Kgsw%3D%3D 10.1111/j.1538-7836.2008.03117.x 18680535
22. A Tripodi PM Mannucci 2007 Abnormalities of hemostasis in chronic liver disease. Reappraisal of their clinical significance and need for clinical and laboratory research J Hepatol 46 727 733 1:CAS:528:DC%2BD2sXjtFGhur0%3D 10.1016/j.jhep.2007.01.015 17316874 (Pubitemid 46400157)
23. A Tripodi LA Ramenghi V Chantarangkul A De Carli M Clerici M Groppo F Mosca PM Mannucci 2008 Normal thrombin generation in neonates in spite of prolonged conventional coagulation tests Haematologica 93 1256 1259 10.3324/haematol.12566 18403390
24. A Tripodi MD Cappellini V Chantarangkul L Padovan MR Fasulo A Marcon PM Mannucci 2009 Hypercoagulability in splenectomized thalassemic patients detected by whole-blood thromboelastometry, but not by thrombin generation in platelet-poor plasma Haematologica 94 150 157 10.3324/haematol.2009.010546
25. B Dahlback 2004 Progress in the understanding of the protein C anticoagulant pathway Int J Hematol 79 109 116 10.1532/IJH97.03149 15005336 (Pubitemid 38281808)
26. F Couturaud J Duchemin C Leroyer B Delahousse JF Abgrall Mottier D, Groupe D'etude De La Thrombose De Bretagne Occidentale (G.E.T.B.O) 2008 Thrombin generation in first-degree relatives of patients with venous thromboembolism who have factor V Leiden. A pilot study Thromb Haemost 99 223 228 1:CAS:528:DC%2BD1cXhtlWis7s%3D 18217158
27. A Tripodi M Primignani V Chantarangkul A Dell'Era M Clerici R de Franchis M Colombo PM Mannucci 2009 An imbalance of pro- vs anti-coagulation factors in plasma from patients with cirrhosis Gastroenterology 137 2105 2111 1:CAS:528:DC%2BD1MXhs1Sisr3I 10.1053/j.gastro.2009.08.045 19706293
28. P Davizon JA López 2009 Microparticles and thrombotic disease Curr Opin Hematol 16 334 341 10.1097/MOH.0b013e32832ea49c 19606028
29. L Burnier P Fontana BR Kwak A Angelillo-Scherrer 2009 Cell-derived microparticles in haemostasis and vascular medicine Thromb Haemost 101 439 451 1:CAS:528:DC%2BD1MXjslSnt7w%3D 19277403
30. W Jy LL Horstman JJ Jimenez YS Ahn E Biró R Nieuwland A Sturk F Dignat-George F Sabatier L Camoin-Jau J Sampol B Hugel F Zobairi JM Freyssinet S Nomura AS Shet NS Key RP Hebbel 2004 Measuring circulating cell-derived microparticles J Thromb Haemost 2 1842 1851 1:STN:280:DC%2BD2cvovVGmsw%3D%3D 10.1111/j.1538-7836.2004.00936.x 15456497 (Pubitemid 40197488)
31. S Nomura 2009 Dynamic role of microparticles in type 2 diabetes mellitus Curr Diabetes Rev 5 245 251 1:CAS:528:DC%2BC3cXislOqurg%3D 10.2174/ 157339909789804404 19531024
32. M Diamant R Nieuwland RF Pablo A Sturk JWA Smit JK Radder 2002 Elevated numbers of tissue factor exposing microparticles correlate with components of the metabolic syndrome in uncomplicated type 2 diabetes mellitus Circulation 106 2442 2447 1:CAS:528:DC%2BD38XotFKrtb8%3D 10.1161/01.CIR.0000036596.59665.C6 12417540 (Pubitemid 35278799)
33. EI Sinauridze DA Kireev NY Popenko AV Pichugin MA Panteleev OV Krymskaya FI Ataullakhanov 2007 Platelet microparticles have 50- to 100-fold higher specific procoagulant activity than activated platelets Thromb Haemost 97 425 434 1:CAS:528:DC%2BD2sXkvVSgurk%3D 17334510 (Pubitemid 46437805)
34. M Franchini PM Mannucci 2009 A new era of anticoagulants Eur J Intern Med 20 562 568 1:CAS:528:DC%2BD1MXhtFyhu73L 10.1016/j.ejim.2009.05.004 19782914