Three Dimensional Structure and Implications for the Catalytic Mechanism of 6-Phosphogluconolactonase from Trypanosoma brucei

Journal of Molecular Biology

Volumn 366, Issue 3, 2007, Pages 868-881

  Delarue, Marc ^a   Duclert Savatier, Nathalie ^a   Miclet, Emeric ^b   Haouz, Ahmed ^a   Giganti, David ^a   Ouazzani, Jamal ^c   Lopez, Philippe ^c   Nilges, Michael ^a   Stoven, Véronique ^d  

^a INSTITUT PASTEUR   (France)

^b Centre National de la Recherche Scientifique   (France)

^c INSTITUT DE CHIMIE DES SUBSTANCES NATURELLES   (France)

^d PSL RESEARCH UNIVERSITY   (France)

Author keywords

6 phosphogluconolactonase; docking; NMR; pentose phosphate pathway; Trypanosoma brucei; X ray structure

Indexed keywords

6 PHOSPHOGLUCONOLACTONASE; GLUCONOLACTONASE; GLUCOSAMINE 6 PHOSPHATE DEAMINASE; UNCLASSIFIED DRUG;

AFRICAN TRYPANOSOMIASIS; AMINO ACID SEQUENCE; ARTICLE; BACILLUS SUBTILIS; CATALYSIS; CRYSTAL STRUCTURE; DRUG DESIGN; ENZYME ANALYSIS; ENZYME MECHANISM; ENZYME STRUCTURE; ESCHERICHIA COLI; LIGAND BINDING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PENTOSE PHOSPHATE CYCLE; PRIORITY JOURNAL; SEQUENCE ALIGNMENT; THERMOTOGA MARITIMA; TRYPANOSOMA BRUCEI; VIBRIO CHOLERAE;

BACILLUS SUBTILIS; BK POLYOMAVIRUS; ESCHERICHIA COLI; THERMOTOGA MARITIMA; TRYPANOSOMA BRUCEI; VIBRIO CHOLERAE;

EID: 33846817140     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2006.11.063     Document Type: Article

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