Ethanol suppresses ureagenesis in rat hepatocytes: Role of acetaldehyde

Journal of Biological Chemistry

Volumn 287, Issue 10, 2012, Pages 7692-7700

  Holmuhamedov, Ekhson L ^a,b,c,e   Czerny, Christoph ^d   Beeson, Craig C ^a,b   Lemasters, John J ^a,b  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^c CENTER FOR THEORETICAL PROBLEMS OF PHYSICOCHEMICAL PHARMACOLOGY   (Russian Federation)

^d GOETHE UNIVERSITY   (Germany)

^e AURORA HEALTH CARE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3-AMINO-1; ALCOHOL DEHYDROGENASE; ALDEHYDE DEHYDROGENASE; BASE LINE; CELLULAR RESPIRATION; CYTOCHROME P450; ETHANOL OXIDATION; HEPATOCYTES; INHIBITORY EFFECT; INTERMEDIATE PRODUCT; INTERMEMBRANE SPACE; ISOTHIOCYANATES; METABOLITE EXCHANGES; OUTER MEMBRANE; RAT HEPATOCYTES; TRANS-1 ,2-DICHLOROETHYLENE; VOLTAGE-DEPENDENT ANION CHANNELS;

ACETALDEHYDE; BIOMOLECULES; METABOLISM; METABOLITES; RATS; UREA;

ETHANOL;

1,2 DICHLOROETHYLENE; 3 AMINO 1,2,3 TRIAZOLE; 4 METHYLPYRAZOLE; ACETALDEHYDE; ALCOHOL DEHYDROGENASE; CYTOCHROME P450 2E1; DEXTRAN; PHENETHYL ISOTHIOCYANATE; RHODAMINE; TRIAZOLE; UNCLASSIFIED DRUG; VOLTAGE DEPENDENT ANION CHANNEL;

ALCOHOL OXIDATION; ALCOHOL PRODUCTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; EXTRACELLULAR SPACE; LIVER CELL CULTURE; LIVER MITOCHONDRION; MALE; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL PERMEABILITY; MITOCHONDRIAL RESPIRATION; NONHUMAN; OUTER MEMBRANE; PRIORITY JOURNAL; RAT; UREA CYCLE;

ACETALDEHYDE; ALCOHOL DEHYDROGENASE; ANIMALS; CATALASE; CENTRAL NERVOUS SYSTEM DEPRESSANTS; CYTOCHROME P-450 CYP2E1; ENZYME ACTIVATORS; ETHANOL; HEPATOCYTES; MALE; MITOCHONDRIA, LIVER; OXYGEN CONSUMPTION; RATS; RATS, SPRAGUE-DAWLEY; UREA; VOLTAGE-DEPENDENT ANION CHANNELS;

RATTUS;

EID: 84857757376     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.293399     Document Type: Article

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