Mechanism of increased respiration in an H+-ATPase-defective mutant of Corynebacterium glutamicum

Journal of Bioscience and Bioengineering

Volumn 113, Issue 4, 2012, Pages 467-473

  Sawada, Kazunori ^a   Kato, Yui ^a   Imai, Keita ^a   Li, Liyuan ^a   Wada, Masaru ^a   Matsushita, Kazunobu ^b   Yokota, Atsushi ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b YAMAGUCHI UNIVERSITY   (Japan)

Author keywords

Corynebacterium glutamicum; Energy deficiency; Energy metabolism; H+ ATPase defect; NADH reoxidation; Respiratory chain

Indexed keywords

CORYNEBACTERIUM GLUTAMICUM; ENERGY DEFICIENCY; ENERGY METABOLISM; RE-OXIDATION; RESPIRATORY CHAINS;

ESCHERICHIA COLI; TRANSCRIPTION;

POLYMERASE CHAIN REACTION;

ADENOSINE TRIPHOSPHATASE; LACTATE DEHYDROGENASE; MALIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; SUCCINATE DEHYDROGENASE;

ARTICLE; BACTERIAL GENE; BACTERIUM CULTURE; CONTROLLED STUDY; CORYNEBACTERIUM GLUTAMICUM; CROSS COUPLING REACTION; DNA MICROARRAY; ENZYME ACTIVITY; FERMENTATION; GENETIC TRANSCRIPTION; GLUCOSE METABOLISM; MICROBIAL RESPIRATION; NONHUMAN; POINT MUTATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

CORYNEBACTERIUM GLUTAMICUM; ELECTRON TRANSPORT; FERMENTATION; GENE EXPRESSION REGULATION, BACTERIAL; MUTATION; NAD; OXIDOREDUCTASES; PROTON-TRANSLOCATING ATPASES;

CORYNEBACTERIUM GLUTAMICUM; ESCHERICHIA COLI;

EID: 84857691400     PISSN: 13891723     EISSN: 13474421     Source Type: Journal    
DOI: 10.1016/j.jbiosc.2011.11.021     Document Type: Article

References (37)

1. Eggeling L., Sahm H. l-Glutamate and l-lysine: traditional products with impetuous developments. Appl. Microbiol. Biotechnol. 1999, 52:146-153.
2. Hermann T. Industrial production of amino acids by coryneform bacteria. J. Biotechnol. 2003, 104:155-172.
3. Okino S., Noburyu R., Suda M., Jojima T., Inui M., Yukawa H. An efficient succinic acid production process in a metabolically engineered Corynebacterium glutamicum strain. Appl. Microbiol. Biotechnol. 2008, 81:459-464.
4. +-ATPase-defective mutant of Corynebacterium glutamicum. Biosci. Biotechnol. Biochem. 2005, 69:1466-1472.
5. 1-ATPase. J. Bacteriol. 2006, 188:6869-6876.
6. +-ATPase defect in Corynebacterium glutamicum abolishes glutamic acid production with enhancement of glucose consumption rate. Appl. Microbiol. Biotechnol. 2001, 57:534-540.
7. 1-ATPase activity. J. Ferment. Bioeng. 1997, 83:132-138.
8. Molenaar D., van der Rest M.E., Drysch A., Yücel R. Functions of the membrane-associated and cytoplasmic malate dehydrogenases in the citric acid cycle of Corynebacterium glutamicum. J. Bacteriol. 2000, 182:6884-6891.
9. 1. Arch. Microbiol. 2001, 175:282-294.
10. Kabus A., Niebisch A., Bott M. Role of cytochrome bd oxidase from Corynebacterium glutamicum in growth and lysine production. Appl. Environ. Microbiol. 2007, 73:861-868.
11. Kusumoto K., Sakiyama M., Sakamoto J., Noguchi S., Sone N. Menaquinol oxidase activity and primary structure of cytochrome bd from the amino-acid fermenting bacterium Corynebacterium glutamicum. Arch. Microbiol. 2000, 173:390-397.
12. Molenaar D., van der Rest M.E., Petrovíc S. Biochemical and genetic characterization of the membrane-associated malate dehydrogenase (acceptor) from Corynebacterium glutamicum. Eur. J. Biochem. 1998, 254:395-403.
13. Nantapong N., Kugimiya Y., Toyama H., Adachi O., Matsushita K. Effect of NADH dehydrogenase-disruption and over-expression on respiration-related metabolism in Corynebacterium glutamicum KY9714. Appl. Microbiol. Biotechnol. 2004, 66:187-193.
14. Nishimura T., Teramoto H., Inui M., Yukawa H. Gene expression profiling of Corynebacterium glutamicum during anaerobic nitrate respiration: induction of the SOS response for cell survival. J. Bacteriol. 2011, 193:1327-1333.
15. +-ATPase-defective mutant of Corynebacterium glutamicum ATCC14067 to energy deficiencies. Proteomics 2007, 7:3348-3357.
16. +-ATPase and C-terminal truncated acetohydroxyacid synthase. Biosci. Biotechnol. Biochem. 2008, 72:2959-2965.
17. Inui M., Murakami S., Okino S., Kawaguchi H., Vertès A.A., Yukawa H. Metabolic analysis of Corynebacterium glutamicum during lactate and succinate productions under oxygen deprivation conditions. J. Mol. Microbiol. Biotechnol. 2004, 7:182-196.
18. Bernofsky C., Swan M. An improved cycling assay for nicotinamide adenine dinucleotide. Anal. Biochem. 1973, 53:452-458.
19. San K.Y., Bennett G.N., Berríos-Rivera S.J., Vadali R.V., Yang Y.T., Horton E., Rudolph F.B., Sariyar B., Blackwood K. Metabolic engineering through cofactor manipulation and its effects on metabolic flux redistribution in Escherichia coli. Metab. Eng. 2002, 4:182-192.
20. Sawada K., Zen-in S., Wada M., Yokota A. Metabolic changes in a pyruvate kinase gene deletion mutant of Corynebacterium glutamicum ATCC 13032. Metab. Eng. 2010, 12:401-407.
21. Kurokawa T., Sakamoto J. Purification and characterization of succinate: menaquinone oxidoreductase from Corynebacterium glutamicum. Arch. Microbiol. 2005, 183:317-324.
22. Schirawski J., Unden G. Menaquinone-dependent succinate dehydrogenase of bacteria catalyzes reversed electron transport driven by the proton potential. Eur. J. Biochem. 1998, 257:210-215.
23. Burstein C., Tiankova L., Kepes A. Respiratory control in Escherichia coli K 12. Eur. J. Biochem. 1979, 94:387-392.
24. Schröder J., Tauch A. Transcriptional regulation of gene expression in Corynebacterium glutamicum: the role of global, master and local regulators in the modular and hierarchical gene regulatory network. FEMS Microbiol. Rev. 2010, 34:685-737.
25. Bussmann M., Emer D., Hasenbein S., Degraf S., Eikmanns B.J., Bott M. Transcriptional control of the succinate dehydrogenase operon sdhCAB of Corynebacterium glutamicum by the cAMP-dependent regulator GlxR and the LuxR-type regulator RamA. J. Biotechnol. 2009, 143:173-182.
26. Cramer A., Gerstmeir R., Schaffer S., Bott M., Eikmanns B.J. Identification of RamA, a novel LuxR-type transcriptional regulator of genes involved in acetate metabolism of Corynebacterium glutamicum. J. Bacteriol. 2006, 188:2554-2567.
27. Auchter M., Cramer A., Hüser A., Rückert C., Emer D., Schwarz P., Arndt A., Lange C., Kalinowski J., Wendisch V.F., Eikmanns B.J. RamA and RamB are global transcriptional regulators in Corynebacterium glutamicum and control genes for enzymes of the central metabolism. J. Biotechnol. 2011, 154:126-139.
28. Gerstmeir R., Cramer A., Dangel P., Schaffer S., Eikmanns B.J. RamB, a novel transcriptional regulator of genes involved in acetate metabolism of Corynebacterium glutamicum. J. Bacteriol. 2004, 186:2798-2809.
29. Kohl T.A., Baumbach J., Jungwirth B., Pühler A., Tauch A. The GlxR regulon of the amino acid producer Corynebacterium glutamicum: in silico and in vitro detection of DNA binding sites of a global transcription regulator. J. Biotechnol. 2008, 135:340-350.
30. Toyoda K., Teramoto H., Inui M., Yukawa H. Genome-wide identification of in vivo binding sites of GlxR, a cyclic AMP receptor protein-type regulator in Corynebacterium glutamicum. J. Bacteriol. 2011, 193:4123-4133.
31. Engels V., Lindner S.N., Wendisch V.F. The global repressor SugR controls expression of genes of glycolysis and of the l-lactate dehydrogenase LdhA in Corynebacterium glutamicum. J. Bacteriol. 2008, 190:8033-8044.
32. Engels V., Wendisch V.F. The DeoR-type regulator SugR represses expression of ptsG in Corynebacterium glutamicum. J. Bacteriol. 2007, 189:2955-2966.
33. Gaigalat L., Schlüter J.P., Hartmann M., Mormann S., Tauch A., Pühler A., Kalinowski J. The DeoR-type transcriptional regulator SugR acts as a repressor for genes encoding the phosphoenolpyruvate:sugar phosphotransferase system (PTS) in Corynebacterium glutamicum. BMC Mol. Biol. 2007, 8:104.
34. Dietrich C., Nato A., Bost B., Le Maréchal P., Guyonvarch A. Regulation of ldh expression during biotin-limited growth of Corynebacterium glutamicum. Microbiology 2009, 155:1360-1375.
35. Toyoda K., Teramoto H., Inui M., Yukawa H. Molecular mechanism of SugR-mediated sugar-dependent expression of the ldhA gene encoding l-lactate dehydrogenase in Corynebacterium glutamicum. Appl. Microbiol. Biotechnol. 2009, 83:315-327.
36. Georgi T., Engels V., Wendisch V.F. Regulation of l-lactate utilization by the FadR-type regulator LldR of Corynebacterium glutamicum. J. Bacteriol. 2008, 190:963-971.
37. Toyoda K., Teramoto H., Inui M., Yukawa H. The ldhA gene, encoding fermentative l-lactate dehydrogenase of Corynebacterium glutamicum, is under the control of positive feedback regulation mediated by LldR. J. Bacteriol. 2009, 191:4251-4258.