Stress can affect drug pharmacokinetics via serum/tissues protein binding and blood flow rate alterations

European Journal of Drug Metabolism and Pharmacokinetics

Volumn 37, Issue 1, 2012, Pages 1-7

  Antonia, Kotsiou ^a   Anastasia, Alevizou ^b   Tesseromatis, Christine ^c  

^a UNIVERSITY OF ATHENS   (Greece)

^b JAMES COOK UNIVERSITY HOSPITAL   (United Kingdom)

^c UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

Author keywords

Drugs; Pharmacokinetics; Stress

Indexed keywords

ALBUMIN; AMPICILLIN; ANTICOAGULANT AGENT; BETA LACTAM ANTIBIOTIC; CEFAPIRIN; CINOXACIN; CIPROFLOXACIN; DIAZEPAM; FATTY ACID; FLURBIPROFEN; HUMAN SERUM ALBUMIN; HYDROCORTISONE; IBUPROFEN; KETOPROFEN; LIDOCAINE; LOCAL ANESTHETIC AGENT; METOPROLOL; MORPHINE; NIFLUMIC ACID; NONSTEROID ANTIINFLAMMATORY AGENT; NORFLOXACIN; OFLOXACIN; OXYPHENBUTAZONE; PEFLOXACIN; PLASMA PROTEIN; PROPRANOLOL; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SALICYLIC ACID; UNINDEXED DRUG; WARFARIN;

ADAPTIVE IMMUNITY; AREA UNDER THE CURVE; BINDING SITE; BLOOD FLOW VELOCITY; BLOOD VESSEL FUNCTION; DRUG ACTIVITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG HALF LIFE; DRUG METABOLISM; DRUG POTENTIATION; DRUG PROTEIN BINDING; DRUG TISSUE LEVEL; HOST RESISTANCE; HUMAN; IMMUNOREGULATION; LIPID TRANSPORT; LIVER BLOOD FLOW; MENTAL STRESS; NONHUMAN; REVIEW; SEIZURE; TISSUE BLOOD FLOW; TREATMENT OUTCOME; UNSPECIFIED SIDE EFFECT;

ANIMALS; BLOOD FLOW VELOCITY; BLOOD PROTEINS; FATTY ACIDS, NONESTERIFIED; HUMANS; PHARMACOKINETICS; PROTEIN BINDING; STRESS, PSYCHOLOGICAL;

EID: 84857653372     PISSN: 03787966     EISSN: 21070180     Source Type: Journal    
DOI: 10.1007/s13318-011-0077-2     Document Type: Review

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