Impact of experimental trauma and niflumic acid administration on antimicrobials' concentration in serum and mandible of rats

Journal of Musculoskeletal Neuronal Interactions

Volumn 6, Issue 3, 2006, Pages 242-246

  Kotsiou, A ^a   Anagnostou, M ^b   Mourouzis, C ^b   Rallis, G ^c   Chantzi, Ch ^a   Tesseromatis, Christine ^b  

^a UNIVERSITY OF ATHENS   (Greece)

^b UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^c KAT HOSPITAL   (Greece)

Author keywords

Ampicillin; Cefapirin; Nilumic acid; Trauma

Indexed keywords

AMPICILLIN; ANTIBIOTIC AGENT; CEFAPIRIN; FATTY ACID; NIFLAMOL; NIFLUMIC ACID; NONSTEROID ANTIINFLAMMATORY AGENT;

ADRENAL GLAND; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBIOTIC THERAPY; ARTICLE; BACILLUS SUBTILIS; CHEEK MUCOSA; CONTROLLED STUDY; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG BONE LEVEL; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG POTENTIATION; DRUG PROTEIN BINDING; FATTY ACID BLOOD LEVEL; MALE; MANDIBLE; NONHUMAN; ORGAN WEIGHT; RAT; STATISTICAL SIGNIFICANCE; STUDENT T TEST; TRAUMATOLOGY; WOUND INFECTION;

AMPICILLIN; ANIMALS; ANTI-BACTERIAL AGENTS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BACILLUS SUBTILIS; CEPHAPIRIN; DRUG INTERACTIONS; DRUG THERAPY, COMBINATION; MALE; MANDIBLE; NIFLUMIC ACID; RATS; RATS, WISTAR; WOUNDS AND INJURIES;

EID: 33750446629     PISSN: 11087161     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (45)

1. Nightingale CH, Bassaris H, Tilton R, Quintiliani R. Changes in pharmacokinetics of cefazolin due to stress. J Pharm Sci 1975; 64:712-714.
2. Shikuma LR, Ackerman BH, Weaver RH, Solem LD, Strate RG, Gerra FB, Zaske DE. Thermal injury effects on drug disposition: a prospective study with piperacillin. J Clin Pharmacol 1990; 30:632-637.
3. Fry DE. The importance of antibiotic pharmacokinetics in critical illness. Am J Surg 1996; 172(6A):20S-25S.
4. Trichilis A, Tesserommatis C, Varonos D. Changes in serum levels of quinolones in rats under the influence of experimental trauma. Eur J Drug Metab Pharmacokinet 2000; 25:73-78.
5. Belzberg H, Zhu J, Cornwell EE III, Murray JA, Sava J, Salim A, Velmahos GC, Gill MA. Imipenem levels are not predictable in the critically ill patients. J Trauma 2004; 56:111-117.
6. Griffeth LK, Rosen GM, Rauckman EJ. Effects of model traumatic injury on hepatic drug metabolism in the rat. V. Sulfation and acetylation. Drug Metab Dispos 1985; 13:398-405.
7. Griffeth LK, Rosen GM, Ranchman EJ. Effects of model traumatic injury on hepatic drug metabolism in the rat. VI. Major detoxification/ toxification pathways. Drug Metab Dispos 1987; 15:749-759.
8. Pollack GM, Browne JL, Marton J, Haberer LJ. Chronic stress impairs oxidative metabolism and hepatic excretion of model xenobiotic substrates in the rat. Drug Metab Dispos 1991; 19:130-134.
9. Rosin E, Ebert S, Uphoff TS, Evans MH, Schultz-Darken NJ. Penetration of antibiotics into the surgical wound in a canine model. Antimicrob Agents Chemother 1989; 33:700-704.
10. Albanese J, Leone M, Bruguerolle B, Ayem ML, Lacarelle B, Martin C. Cerebrospinal fluid penetration and pharmacokinetics of vancomycin administered by continuous infusion to mechanically ventilated patients in an intensive care unit. Antimicrob Agents Chemother 2000; 44:1356-1358.
11. Torres-Molina F, Peris JE, Garcia-Carbonell MC, Aristorena JC, Gi L, Chesa-Jimenez J. Use of rats chronically cannulated in the jugular vein and the duodenum in pharmacokinetic studies. Effect of ether anesthesia on absorption of amoxicillin. Arzneimittelforschung 1996; 46:716-719.
12. Hijazi Y, Bodonian C, Bolon M, Salord F, Boulieu R. Pharmacokinetics and haemodynamics of ketamine in intensive care patients with brain or spinal cord injury. Br J Anaesth 2003; 90:155-160.
13. Saranteas T, Mourouzis C, Dannis C, Alexopoulos C, Lolis E, Tesseromatis C. Effect of various stress models on lidocaine pharmacokinetic properties in the mandible after masseter injection. J Oral Maxillofac Surg 2004; 62:858-862.
14. Saranteas T, Tesserommatis C, Potamianou A, Mourouzis C, Varonos D. Stress induced lidocaine modification in serum and tissues. Eur J Drug Metab Pharmacokin 2002; 27:229-232.
15. Tesseromatis C, Trichilis A, Tsivos E, Messari J, Triantaphyllidis H, Varonos DD. Does stress influence ampicillin concentration in serum and tissues? Eur J Drug Metab Pharmacokinet 2001; 26:167-171.
16. Verbeeck RK. Pharmacokinetic drug interactions with non-steroidal anti-inflammatory drugs. Clin Pharmacokinet 1990; 19:44-66.
17. Carsenti-Etesse H, Farinotti R, Durant J, Roger PM, De Salvador F, Bernard E, Rouveix B, Dellamonica. P. Pharmacokinetic parameters and killing rates in serum of volunteers receiving amoxicillin, cefadroxil or cefixime alone or associated with niflumic acid or paracetamol. Eur J Drug Metab Pharmacokin 1998; 23:357-366.
18. Trichilis A, Saranteas T, Potamianou A, Mourouzis C, Tesserommatis C. Quinolone levels in serum and maxillofacial tissues under ibuprofen co-administration following surgical trauma. J Musculoskelet Neuronal Interact 2003; 3:170-175.
19. Dontas I, Sokolis DP, Giamarellos-Bourboulis EJ, Tzonou A, Giamarellou H, Karayanacos PE. The influence of indomethacin co-administration on ofloxacin levels in plasma and cerebrospinal fluid in rats. Int J Antimicrob Agents 2004; 23:371-376.
20. Sauvage JP, Ditisheim A, Bessede JP, David N. Double-blind, placebo-controlled, multi-centre trial of the efficacy and tolerance of niflumic acid ('Nifluril') capsules in the treatment of tonsillitis in adults. Curr Med Res Opin 1990; 11:631-637.
21. Committee on Care and Use of Laboratory Animals. Guides for the care and use of laboratory animals. Washington, DC: Institute of Laboratory Animals and Resources. National Research Council; 1985:83.
22. Erlendsdottir H, Knudsen JD, Odenholt I, Cars O, Espersen F, Frimodt-Møller N, Fuursted K, Kristinsson KG, Gudmundsson S. Penicillin pharmacodynamics in four experimental pneumococcal infection models. Antimicrob Agents Chemother 2001; 45:1078-1085.
23. Longa GJ and Cross RE, Laboratory Monitoring of Drug Therapy. Part II: Variable Protein Binding and Free (Unbound) Drug Concentration. Bulletin of Laboratory Medicine 1984; 80:1-6.
24. Speight TM and Holford NHG. Avery's Drug Treatment 4th Edition Adis International, Barcelona; 1997:1647.
25. Houin G, Tremblay D, Bree F, Dufour A, Ledudal P, Tillement JP. The pharmacokinetics and availability of niflumic acid in humans. Int J Clin Pharmacol Ther Toxicol 1983; 21:130-134.
26. Bennet VJ, Brodie IJ, Benner IE, Kirby NW. Simplified accurate method to antibiotic assay of clinical specimens. App Microbio 1966; 14:170-177.
27. Neschen S, Moore I, Regittnig W, Yu CL, Wang Y, Pypaert M, Petersen KF, Shulman GI. Contrasting effects of fish oil and safflower oil on hepatic peroxisomal and tissue lipid content. Am J Physiol Endocrinol Metab 2002; 282:E395-401.
28. Harri MN, Narvola I. Physical training under the influence of beta blockade in rats: effect on adrenergic responses. Eur J Appl Physiol Occup Physiol 1979; 41:199-210.
29. Droste SK, Gesing A, Ulbricht S, Muller MB, Linthorst AC, Reul JM. Effects of long-term voluntary exercise on the mouse hypothalamic-pituitary-adrenocortical axis. Endocrinology 2003; 144:3012-3023.
30. Garrelts JC, Jost G, Kowalsky SF, Krol GJ, Lettieri JT. Ciprofloxacin pharmacokinetics in burn patients. Antimicrob Agents Chemother 1996; 40:1153-1156.
31. Weinbren MJ. Pharmacokinetics of antibiotics in burn patients. J Antimicrob Chemother 1999; 44:319-327.
32. Dhillon HS, Carbary T, Dose J, Dempsey RJ, Prasad MR. Activation of phosphatidylinositol biphosphate signal transduction pathway after experimental brain injury: a lipid study. Brain Res 1995; 698:100-106.
33. Suh B, Craig WA, England AC, Elliot RL. Effect of free fatty acids on protein binding of antimicrobial agents. J Infect Dis 1981; 143:609-616.
34. Dhillon HS, Dose JM, Scheff SW, Prasad MR. Time course of changes in lactate and free fatty acids after experimental brain injury and relationship to morphologic damage. Exp Neurol 1997; 146:240-249.
35. Tesseromatis C, Tsopanakis C, Symeonoglou G, Loukissa M, Varonos D. How harmless is FFA enhancement? Eur Drug Metab Pharmacokinet 1996; 21:213-215.
36. Giamarellos-Bourboulis EJ, Mouktaroudi M, Adamis T, Koussoulas V, Baziaka F, Perrea D, Karayannacos PE, Giamarellou H. n-6 polyunsaturated fatty acids enhance the activities of ceftazidime and amikacin in experimental sepsis caused by multidrug-resistant Pseudomonas aeruginosa. Antimicrob Agents Chemother 2004; 48:4713-4717.
37. Craig WA, Suh B. Changes in protein binding during disease. Scand J Infect Dis Suppl 1978; 239-244.
38. Ronchera-Oms CL, Tormo C, Ordovas JP, Abad J, Jimenez NV. Expanded gentamicin volume of distribution in critically ill adult patients receiving total parenteral nutrition. J Clin Pharm Ther 1995; 20:253-258.
39. Kongstad L, Moller AD, Grande PO. Reflection coefficient for albumin and capillary fluid permeability in cat calf muscle after traumatic injury. Acta Physiologica Scandinavica 1999; 165:369-377.
40. Baker ME. Albumin, steroid hormones and the origin of vertebrates. J Endocrinol 2002; 175:121-127.
41. Hiraoka H, Yamamoto V, Okano N, Morita T, Goto F, Horiuchi R. Changes in drug plasma concentrations of an extensively bound and highly extracted drug, propofol, in response to altered plasma binding. Clin Pharmacol Ther 2004; 75:324-330.
42. Scheife RT. Protein binding: what does it mean? DICP 1989; 23(7-8 Suppl):S27-31.
43. Tesseromatis C, Fichtl B, Kurz H. Binding of non-steroid anti-inflammatory drugs and warfarin to liver tissue of rabbits in vitro. Eur J Drug Metab Pharmacokinet 1987; 12:161-167.
44. Tesserommatis C, Saranteas T, Chatzijanni E, Anagnostopoulou S, Cotsiou A, Chatzi C. Modifications of clonidine binding to rabbit liver protein under the influence of non-steroid anti-inflammatory drugs in vitro. Eur J Drug Metab Pharmacokinet 2003; 28:245-247.
45. Firth EC, Nouws JF, Klein WR, Driessens F. The effect of phenylbutazone on the plasma disposition of penicillin G in the horse. J Vet Pharmacol Ther 1990; 13:179-185.