Chronic intermittent hypoxia induces local inflammation of the rat carotid body via functional upregulation of proinflammatory cytokine pathways

Histochemistry and Cell Biology

Volumn 137, Issue 3, 2012, Pages 303-317

  Lam, Siu Yin ^a   Liu, Yu ^a   Ng, Kwong Man ^a   Lau, Chi Fai ^a   Liong, Emily C ^a   Tipoe, George L ^a   Fung, Man Lung ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Carotid body; Intermittent hypoxia; Oxidative stress; Proinflammatory cytokines; Sleep apnea

Indexed keywords

8 ISOPROSTANE; CALCIUM ION; CHEMOKINE RECEPTOR CCR2; CYTOKINE; CYTOKINE RECEPTOR; DEXAMETHASONE; GLYCOPROTEIN GP 130; IBUPROFEN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1 RECEPTOR TYPE I; INTERLEUKIN 1BETA; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN P22PHOX; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 1; TYROSINE 3 MONOOXYGENASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CAROTID BODY; CELL HYPOXIA; CELL INFILTRATION; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG EFFECT; HYPOXIA; INFLAMMATION; INTERMITTENT HYPOXIA; MACROPHAGE; MALE; NONHUMAN; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SLEEP APNEA SYNDROME; UPREGULATION;

ANIMALS; ANOXIA; ANTI-INFLAMMATORY AGENTS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CALCIUM; CAROTID ARTERY, INTERNAL; CAROTID BODY; CHRONIC DISEASE; CYTOKINES; DEXAMETHASONE; DISEASE MODELS, ANIMAL; GENE EXPRESSION; IBUPROFEN; MALE; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CYTOKINE; SIGNAL TRANSDUCTION; SLEEP APNEA SYNDROMES; UP-REGULATION; VASCULITIS;

GLOMUS; RATTUS;

EID: 84857625513     PISSN: 09486143     EISSN: 1432119X     Source Type: Journal    
DOI: 10.1007/s00418-011-0900-5     Document Type: Article

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