메뉴 건너뛰기




Volumn 114, Issue 4, 2008, Pages 261-266

Intermittent hypoxia and activation of inflammatory molecular pathways in OSAS

Author keywords

Cardiovascular disease; Inflammation; Intermittent hypoxia; Obstructive sleep apnoea syndrome

Indexed keywords

CYTOKINE;

EID: 54349109849     PISSN: 13813455     EISSN: 17444160     Source Type: Journal    
DOI: 10.1080/13813450802307337     Document Type: Review
Times cited : (90)

References (62)
  • 1
    • 24644452600 scopus 로고    scopus 로고
    • Effects of long-term nasal continuous positive airway pressure on C-reactive protein in patients with obstructive sleep apnea syndrome
    • Akashiba T, Akahoshi T, Kawahara S, Majima T, Horie T. 2005. Effects of long-term nasal continuous positive airway pressure on C-reactive protein in patients with obstructive sleep apnea syndrome. Intern Med 44:899-900.
    • (2005) Intern Med , vol.44 , pp. 899-900
    • Akashiba, T.1    Akahoshi, T.2    Kawahara, S.3    Majima, T.4    Horie, T.5
  • 2
    • 33846906889 scopus 로고    scopus 로고
    • Obesity, metabolic syndrome and sleep apnoea: All pro-inflammatory states
    • Alam I, Lewis K, Stephens JW, Baxter JN. 2007. Obesity, metabolic syndrome and sleep apnoea: all pro-inflammatory states. Obes Rev 8:119-27.
    • (2007) Obes Rev , vol.8 , pp. 119-127
    • Alam, I.1    Lewis, K.2    Stephens, J.W.3    Baxter, J.N.4
  • 3
    • 33745901383 scopus 로고    scopus 로고
    • Lipid peroxides, superoxide dismutase and circulating IL-8 and GCP-2 in patients with severe obstructive sleep apnea: A pilot study
    • Alzoghaibi MA, Bahammam AS. 2005. Lipid peroxides, superoxide dismutase and circulating IL-8 and GCP-2 in patients with severe obstructive sleep apnea: a pilot study. Sleep Breath 9:119-26.
    • (2005) Sleep Breath , vol.9 , pp. 119-126
    • Alzoghaibi, M.A.1    Bahammam, A.S.2
  • 4
    • 3242667810 scopus 로고    scopus 로고
    • Effects of obesity on C-reactive protein level and metabolic disturbances in male patients with obstructive sleep apnea
    • Barcelo A, Barbe F, Llompart E, Mayoralas LR, Ladaria A, Bosch M, Agusti AG. 2004. Effects of obesity on C-reactive protein level and metabolic disturbances in male patients with obstructive sleep apnea. Am J Med 117:118-21.
    • (2004) Am J Med , vol.117 , pp. 118-121
    • Barcelo, A.1    Barbe, F.2    Llompart, E.3    Mayoralas, L.R.4    Ladaria, A.5    Bosch, M.6    Agusti, A.G.7
  • 5
    • 2342464085 scopus 로고    scopus 로고
    • The two NF-kappaB activation pathways and their role in innate and adaptive immunity
    • Bonizzi G, Karin M. 2004. The two NF-kappaB activation pathways and their role in innate and adaptive immunity. Trends Immunol 25:280-88.
    • (2004) Trends Immunol , vol.25 , pp. 280-288
    • Bonizzi, G.1    Karin, M.2
  • 7
    • 34347337594 scopus 로고    scopus 로고
    • Association of carotid artery intima-media thickness, plaques, and C-reactive protein with future cardiovascular disease and all-cause mortality: The Cardiovascular Health Study
    • Cao JJ, Arnold AM, Manolio TA, Polak JF, Psaty BM, Hirsch CH, Kuller LH, Cushman M. 2007. Association of carotid artery intima-media thickness, plaques, and C-reactive protein with future cardiovascular disease and all-cause mortality: the Cardiovascular Health Study. Circulation 116:32-8.
    • (2007) Circulation , vol.116 , pp. 32-38
    • Cao, J.J.1    Arnold, A.M.2    Manolio, T.A.3    Polak, J.F.4    Psaty, B.M.5    Hirsch, C.H.6    Kuller, L.H.7    Cushman, M.8
  • 8
    • 4644288261 scopus 로고    scopus 로고
    • The relationship between serum cytokine levels with obesity and obstructive sleep apnea syndrome
    • Ciftci TU, Kokturk O, Bukan N, Bilgihan A. 2004. The relationship between serum cytokine levels with obesity and obstructive sleep apnea syndrome. Cytokine 28:87-91.
    • (2004) Cytokine , vol.28 , pp. 87-91
    • Ciftci, T.U.1    Kokturk, O.2    Bukan, N.3    Bilgihan, A.4
  • 9
    • 0033179153 scopus 로고    scopus 로고
    • Activation of c-Jun N-terminal kinases and p38-mitogen-activated protein kinases in human heart failure secondary to ischaemic heart disease
    • Cook SA, Sugden PH, Clerk A. 1999. Activation of c-Jun N-terminal kinases and p38-mitogen-activated protein kinases in human heart failure secondary to ischaemic heart disease. J Mol Cell Cardiol 31:1429-34.
    • (1999) J Mol Cell Cardiol , vol.31 , pp. 1429-1434
    • Cook, S.A.1    Sugden, P.H.2    Clerk, A.3
  • 10
    • 25644446823 scopus 로고    scopus 로고
    • Hypoxia-responsive transcription factors
    • Cummins EP, Taylor CT. 2005. Hypoxia-responsive transcription factors. Pflugers Arch 450:363-71.
    • (2005) Pflugers Arch , vol.450 , pp. 363-371
    • Cummins, E.P.1    Taylor, C.T.2
  • 11
    • 21844465408 scopus 로고    scopus 로고
    • Long-term effects of nasal continuous positive airway pressure therapy on cardiovascular outcomes in sleep apnea syndrome
    • Doherty LS, Kiely JL, Swan V, McNicholas WT. 2005. Long-term effects of nasal continuous positive airway pressure therapy on cardiovascular outcomes in sleep apnea syndrome. Chest 127:2076-84.
    • (2005) Chest , vol.127 , pp. 2076-2084
    • Doherty, L.S.1    Kiely, J.L.2    Swan, V.3    McNicholas, W.T.4
  • 12
    • 0036528981 scopus 로고    scopus 로고
    • Increased adhesion molecules expression and production of reactive oxygen species in leukocytes of sleep apnea patients
    • Dyugovskaya L, Lavie P, Lavie L. 2002. Increased adhesion molecules expression and production of reactive oxygen species in leukocytes of sleep apnea patients. Am J Respir Crit Care Med 165:934-9.
    • (2002) Am J Respir Crit Care Med , vol.165 , pp. 934-939
    • Dyugovskaya, L.1    Lavie, P.2    Lavie, L.3
  • 13
    • 0042165846 scopus 로고    scopus 로고
    • Phenotypic and functional characterization of blood gammadelta T cells in sleep apnea
    • Dyugovskaya L, Lavie P, Lavie L. 2003. Phenotypic and functional characterization of blood gammadelta T cells in sleep apnea. Am J Respir Crit Care Med 168:242-9.
    • (2003) Am J Respir Crit Care Med , vol.168 , pp. 242-249
    • Dyugovskaya, L.1    Lavie, P.2    Lavie, L.3
  • 14
    • 25444479083 scopus 로고    scopus 로고
    • Lymphocyte activation as a possible measure of atherosclerotic risk in patients with sleep apnea
    • Dyugovskaya L, Lavie P, Lavie L. 2005. Lymphocyte activation as a possible measure of atherosclerotic risk in patients with sleep apnea. Ann NY Acad Sci 1051:340-50.
    • (2005) Ann NY Acad Sci , vol.1051 , pp. 340-350
    • Dyugovskaya, L.1    Lavie, P.2    Lavie, L.3
  • 15
    • 0036247736 scopus 로고    scopus 로고
    • Adhesion molecules in patients with coronary artery disease and moderate-to-severe obstructive sleep apnea
    • El-Solh AA, Mador MJ, Sikka P, Dhillon RS, Amsterdam D, Grant BJ. 2002. Adhesion molecules in patients with coronary artery disease and moderate-to-severe obstructive sleep apnea. Chest 121:1541-7.
    • (2002) Chest , vol.121 , pp. 1541-1547
    • El-Solh, A.A.1    Mador, M.J.2    Sikka, P.3    Dhillon, R.S.4    Amsterdam, D.5    Grant, B.J.6
  • 16
    • 3142592388 scopus 로고    scopus 로고
    • Sleep 4: Sleepiness, cognitive function, and quality of life in obstructive sleep apnoea/ hypopnoea syndrome
    • Engleman HM, Douglas NJ. 2004. Sleep 4: Sleepiness, cognitive function, and quality of life in obstructive sleep apnoea/ hypopnoea syndrome. Thorax 59:618-22.
    • (2004) Thorax , vol.59 , pp. 618-622
    • Engleman, H.M.1    Douglas, N.J.2
  • 17
    • 18144408371 scopus 로고    scopus 로고
    • Adipose tissue, adipokines, and inflammation
    • quiz 920
    • Fantuzzi G. 2005. Adipose tissue, adipokines, and inflammation. J Allergy Clin Immunol 115:911-19; quiz 920.
    • (2005) J Allergy Clin Immunol , vol.115 , pp. 911-919
    • Fantuzzi, G.1
  • 18
    • 0035936802 scopus 로고    scopus 로고
    • Atherosclerosis the road ahead
    • Glass CK, Witztum JL. 2001. Atherosclerosis the road ahead. Cell 104:503-16.
    • (2001) Cell , vol.104 , pp. 503-516
    • Glass, C.K.1    Witztum, J.L.2
  • 20
    • 11144256430 scopus 로고    scopus 로고
    • C-reactive protein and sleep-disordered breathing
    • Guilleminault C, Kirisoglu C, Ohayon MM. 2004. C-reactive protein and sleep-disordered breathing. Sleep 27:1507-11.
    • (2004) Sleep , vol.27 , pp. 1507-1511
    • Guilleminault, C.1    Kirisoglu, C.2    Ohayon, M.M.3
  • 22
    • 0031054058 scopus 로고    scopus 로고
    • Production of C-reactive protein and risk of coronary events in stable and unstable angina. European Concerted Action on Thrombosis and Disabilities Angina Pectoris Study Group
    • Haverkate F, Thompson SG, Pyke SD, Gallimore JR, Pepys MB. 1997. Production of C-reactive protein and risk of coronary events in stable and unstable angina. European Concerted Action on Thrombosis and Disabilities Angina Pectoris Study Group. Lancet 349:462-6.
    • (1997) Lancet , vol.349 , pp. 462-466
    • Haverkate, F.1    Thompson, S.G.2    Pyke, S.D.3    Gallimore, J.R.4    Pepys, M.B.5
  • 25
    • 0033912018 scopus 로고    scopus 로고
    • Cardiovascular risk factors in patients with obstructive sleep apnoea syndrome
    • Kiely JL, McNicholas WT. 2000. Cardiovascular risk factors in patients with obstructive sleep apnoea syndrome. Eur Respir J 16:128-33.
    • (2000) Eur Respir J , vol.16 , pp. 128-133
    • Kiely, J.L.1    McNicholas, W.T.2
  • 27
    • 0037316130 scopus 로고    scopus 로고
    • Obstructive sleep apnoea syndrome-an oxidative stress disorder
    • Lavie L. 2003. Obstructive sleep apnoea syndrome-an oxidative stress disorder. Sleep Med Rev 7:35-51.
    • (2003) Sleep Med Rev , vol.7 , pp. 35-51
    • Lavie, L.1
  • 28
    • 18844461232 scopus 로고    scopus 로고
    • M, Georgakopoulos D, Lu G, Hester L, Kass DA, Hasday J, Wang Y. 2005. p38 MAP kinase mediates inflammatory cytokine induction in cardiomyocytes and extracellular matrix remodeling in heart. Circulation 111:2494-502.
    • M, Georgakopoulos D, Lu G, Hester L, Kass DA, Hasday J, Wang Y. 2005. p38 MAP kinase mediates inflammatory cytokine induction in cardiomyocytes and extracellular matrix remodeling in heart. Circulation 111:2494-502.
  • 30
    • 15244344823 scopus 로고    scopus 로고
    • Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure: An observational study
    • Marin JM, Carrizo SJ, Vicente E, Agusti AG. 2005. Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure: an observational study. Lancet 365:1046-53.
    • (2005) Lancet , vol.365 , pp. 1046-1053
    • Marin, J.M.1    Carrizo, S.J.2    Vicente, E.3    Agusti, A.G.4
  • 31
    • 33846188093 scopus 로고    scopus 로고
    • Sleep apnoea as an independent risk factor for cardiovascular disease: Current evidence, basic mechanisms and research priorities
    • McNicholas WT, Bonsigore MR. 2007. Sleep apnoea as an independent risk factor for cardiovascular disease: current evidence, basic mechanisms and research priorities. Eur Respir J 29:156-78.
    • (2007) Eur Respir J , vol.29 , pp. 156-178
    • McNicholas, W.T.1    Bonsigore, M.R.2
  • 33
    • 26444571326 scopus 로고    scopus 로고
    • High attributable risk of elevated C-reactive protein level to conventional coronary heart disease risk factors: The Third National Health and Nutrition Examination Survey
    • Miller M, Zhan M, Havas S. 2005. High attributable risk of elevated C-reactive protein level to conventional coronary heart disease risk factors: the Third National Health and Nutrition Examination Survey. Arch Intern Med 165:2063-68.
    • (2005) Arch Intern Med , vol.165 , pp. 2063-2068
    • Miller, M.1    Zhan, M.2    Havas, S.3
  • 34
    • 8744224469 scopus 로고    scopus 로고
    • Elevated production of tumor necrosis factor-alpha by monocytes in patients with obstructive sleep apnea syndrome
    • Minoguchi K, Tazaki T, Yokoe T, Minoguchi H, Watanabe Y, Yamamoto M, Adachi M. 2004. Elevated production of tumor necrosis factor-alpha by monocytes in patients with obstructive sleep apnea syndrome. Chest 126:1473-79.
    • (2004) Chest , vol.126 , pp. 1473-1479
    • Minoguchi, K.1    Tazaki, T.2    Yokoe, T.3    Minoguchi, H.4    Watanabe, Y.5    Yamamoto, M.6    Adachi, M.7
  • 37
    • 0037215191 scopus 로고    scopus 로고
    • Effects of obstructive sleep apnea on circulating ICAM-1, IL-8, and MCP-1
    • Ohga E, Tomita T, Wada H, Yamamoto H, Nagase T, Ouchi Y. 2003. Effects of obstructive sleep apnea on circulating ICAM-1, IL-8, and MCP-1. J Appl Physiol 94:179-84.
    • (2003) J Appl Physiol , vol.94 , pp. 179-184
    • Ohga, E.1    Tomita, T.2    Wada, H.3    Yamamoto, H.4    Nagase, T.5    Ouchi, Y.6
  • 38
    • 0037099155 scopus 로고    scopus 로고
    • Increased incidence of cardiovascular disease in middle-aged men with obstructive sleep apnea: A 7-year follow-up
    • Peker Y, Hedner J, Norum J, Kraiczi H, Carlson J. 2002. Increased incidence of cardiovascular disease in middle-aged men with obstructive sleep apnea: a 7-year follow-up. Am J Respir Crit Care Med 166:159-65.
    • (2002) Am J Respir Crit Care Med , vol.166 , pp. 159-165
    • Peker, Y.1    Hedner, J.2    Norum, J.3    Kraiczi, H.4    Carlson, J.5
  • 39
    • 0034636477 scopus 로고    scopus 로고
    • Prospective study of the association between sleep-disordered breathing and hypertension
    • Peppard PE, Young T, Palta M, Skatrud J. 2000. Prospective study of the association between sleep-disordered breathing and hypertension. N Engl J Med 342:1378-84.
    • (2000) N Engl J Med , vol.342 , pp. 1378-1384
    • Peppard, P.E.1    Young, T.2    Palta, M.3    Skatrud, J.4
  • 40
    • 0032566401 scopus 로고    scopus 로고
    • Prospective study of C-reactive protein and the risk of future cardiovascular events among apparently healthy women
    • Ridker PM, Buring JE, Shih J, Matias M, Hennekens CH. 1998. Prospective study of C-reactive protein and the risk of future cardiovascular events among apparently healthy women. Circulation 98:731-3.
    • (1998) Circulation , vol.98 , pp. 731-733
    • Ridker, P.M.1    Buring, J.E.2    Shih, J.3    Matias, M.4    Hennekens, C.H.5
  • 41
    • 33847267684 scopus 로고    scopus 로고
    • A critical role for p38 map kinase in NF-kappaB signaling during intermittent hypoxia/reoxygenation
    • Ryan S, McNicholas WT, Taylor CT. 2007a. A critical role for p38 map kinase in NF-kappaB signaling during intermittent hypoxia/reoxygenation. Biochem Biophys Res Commun 355:28-733.
    • (2007) Biochem Biophys Res Commun , vol.355 , pp. 28-733
    • Ryan, S.1    McNicholas, W.T.2    Taylor, C.T.3
  • 42
    • 34250339549 scopus 로고    scopus 로고
    • Cardiovascular risk markers in obstructive sleep apnoea syndrome and correlation with obesity
    • Ryan S, Nolan GM, Hannigan E, Cunningham S, Taylor C, McNicholas WT. 2007b. Cardiovascular risk markers in obstructive sleep apnoea syndrome and correlation with obesity. Thorax 62:509-14.
    • (2007) Thorax , vol.62 , pp. 509-514
    • Ryan, S.1    Nolan, G.M.2    Hannigan, E.3    Cunningham, S.4    Taylor, C.5    McNicholas, W.T.6
  • 43
    • 27444448072 scopus 로고    scopus 로고
    • Selective activation of inflammatory pathways by intermittent hypoxia in obstructive sleep apnea syndrome
    • Ryan S, Taylor CT, McNicholas WT. 2005. Selective activation of inflammatory pathways by intermittent hypoxia in obstructive sleep apnea syndrome. Circulation 112:2660-67.
    • (2005) Circulation , vol.112 , pp. 2660-2667
    • Ryan, S.1    Taylor, C.T.2    McNicholas, W.T.3
  • 44
    • 33749427050 scopus 로고    scopus 로고
    • Predictors of elevated nuclear factor-kappaB-dependent genes in obstructive sleep apnea syndrome
    • Ryan S, Taylor CT, McNicholas WT. 2006. Predictors of elevated nuclear factor-kappaB-dependent genes in obstructive sleep apnea syndrome. Am J Respir Crit Care Med 174:824-30.
    • (2006) Am J Respir Crit Care Med , vol.174 , pp. 824-830
    • Ryan, S.1    Taylor, C.T.2    McNicholas, W.T.3
  • 45
    • 33745571226 scopus 로고    scopus 로고
    • Structural and serum surrogate markers of cerebrovascular disease in obstructive sleep apnea (OSA). Association of mild OSA with early atherosclerosis
    • Saletu M, Nosiska D, Kapfhammer G, Lalouschek W, Saletu B, Benesch T, Zeitlhofer J. 2006. Structural and serum surrogate markers of cerebrovascular disease in obstructive sleep apnea (OSA). Association of mild OSA with early atherosclerosis. J Neurol 253:746-52.
    • (2006) J Neurol , vol.253 , pp. 746-752
    • Saletu, M.1    Nosiska, D.2    Kapfhammer, G.3    Lalouschek, W.4    Saletu, B.5    Benesch, T.6    Zeitlhofer, J.7
  • 46
    • 0033845075 scopus 로고    scopus 로고
    • Enhanced release of superoxide from polymorphonuclear neutrophils in obstructive sleep apnea Impact of continuous positive airway pressure therapy
    • Schulz R, Mahmoudi S, Hattar K, Sibelius U, Olschewski H, Mayer K, Seeger W, Grimminger F. 2000. Enhanced release of superoxide from polymorphonuclear neutrophils in obstructive sleep apnea Impact of continuous positive airway pressure therapy. Am J Respir Crit Care Med 162:566-70.
    • (2000) Am J Respir Crit Care Med , vol.162 , pp. 566-570
    • Schulz, R.1    Mahmoudi, S.2    Hattar, K.3    Sibelius, U.4    Olschewski, H.5    Mayer, K.6    Seeger, W.7    Grimminger, F.8
  • 47
    • 1342346637 scopus 로고    scopus 로고
    • O2-regulated gene expression: Transcriptional control of cardiorespiratory physiology by HIF-1
    • discussion 1170-72
    • Semenza GL. 2004. O2-regulated gene expression: transcriptional control of cardiorespiratory physiology by HIF-1. J Appl Physiol 96:1173-7; discussion 1170-72.
    • (2004) J Appl Physiol , vol.96 , pp. 1173-1177
    • Semenza, G.L.1
  • 49
    • 35448991656 scopus 로고    scopus 로고
    • Effect of continuous positive airway pressure treatment on serum cardiovascular risk factors in patients with obstructive sleep apnea-hypopnea syndrome
    • Steiropoulos P, Tsara V, Nena E, Fitili C, Kataropoulou M, Froudarakis M, Christaki P, Bouros D. 2007. Effect of continuous positive airway pressure treatment on serum cardiovascular risk factors in patients with obstructive sleep apnea-hypopnea syndrome. Chest 132:843-51.
    • (2007) Chest , vol.132 , pp. 843-851
    • Steiropoulos, P.1    Tsara, V.2    Nena, E.3    Fitili, C.4    Kataropoulou, M.5    Froudarakis, M.6    Christaki, P.7    Bouros, D.8
  • 50
    • 0029016138 scopus 로고
    • Sleep and sleep-disordered breathing in commercial long-haul truck drivers
    • Stoohs RA, Bingham LA, Itoi A, Guilleminault C, Dement WC. 1995. Sleep and sleep-disordered breathing in commercial long-haul truck drivers. Chest 107:1275-82.
    • (1995) Chest , vol.107 , pp. 1275-1282
    • Stoohs, R.A.1    Bingham, L.A.2    Itoi, A.3    Guilleminault, C.4    Dement, W.C.5
  • 51
    • 0019420178 scopus 로고
    • Reversal of obstructive sleep apnoea by continuous positive airway pressure applied through the nares
    • Sullivan CE, Issa FG, Berthon-Jones M, Eves L. 1981. Reversal of obstructive sleep apnoea by continuous positive airway pressure applied through the nares. Lancet 1:862-5.
    • (1981) Lancet , vol.1 , pp. 862-865
    • Sullivan, C.E.1    Issa, F.G.2    Berthon-Jones, M.3    Eves, L.4
  • 52
    • 34547690717 scopus 로고    scopus 로고
    • Correlates of serum C-reactive protein (CRP)-no association with sleep duration or sleep disordered breathing
    • Taheri S, Austin D, Lin L, Nieto FJ, Young T, Mignot E. 2007. Correlates of serum C-reactive protein (CRP)-no association with sleep duration or sleep disordered breathing. Sleep 30:991-6.
    • (2007) Sleep , vol.30 , pp. 991-996
    • Taheri, S.1    Austin, D.2    Lin, L.3    Nieto, F.J.4    Young, T.5    Mignot, E.6
  • 54
    • 4544300051 scopus 로고    scopus 로고
    • Marked decrease in sleepiness in patients with sleep apnea by etanercept, a tumor necrosis factor-alpha antagonist
    • Vgontzas AN, Zoumakis E, Lin HM, Bixler EO, Trakada G, Chrousos GP. 2004. Marked decrease in sleepiness in patients with sleep apnea by etanercept, a tumor necrosis factor-alpha antagonist. J Clin Endocrinol Metab 89:4409-13.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 4409-4413
    • Vgontzas, A.N.1    Zoumakis, E.2    Lin, H.M.3    Bixler, E.O.4    Trakada, G.5    Chrousos, G.P.6
  • 55
    • 2642535951 scopus 로고    scopus 로고
    • Inflammation as a cardiovascular risk factor
    • Willerson JT, Ridker PM. 2004. Inflammation as a cardiovascular risk factor. Circulation 109:II2-10.
    • (2004) Circulation , vol.109
    • Willerson, J.T.1    Ridker, P.M.2
  • 57
  • 58
    • 0037418181 scopus 로고    scopus 로고
    • Elevated levels of C-reactive protein and interleukin-6 in patients with obstructive sleep apnea syndrome are decreased by nasal continuous positive airway pressure
    • Yokoe T, Minoguchi K, Matsuo H, Oda N, Minoguchi H, Yoshino G, Hirano T, Adachi M. 2003. Elevated levels of C-reactive protein and interleukin-6 in patients with obstructive sleep apnea syndrome are decreased by nasal continuous positive airway pressure. Circulation 107:1129-34.
    • (2003) Circulation , vol.107 , pp. 1129-1134
    • Yokoe, T.1    Minoguchi, K.2    Matsuo, H.3    Oda, N.4    Minoguchi, H.5    Yoshino, G.6    Hirano, T.7    Adachi, M.8
  • 59
    • 0027462562 scopus 로고
    • The occurrence of sleep-disordered breathing among middle-aged adults
    • Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S. 1993. The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med 328:1230-35.
    • (1993) N Engl J Med , vol.328 , pp. 1230-1235
    • Young, T.1    Palta, M.2    Dempsey, J.3    Skatrud, J.4    Weber, S.5    Badr, S.6
  • 60
  • 61
    • 14244256421 scopus 로고    scopus 로고
    • Ca2+/calmodulin kinase-dependent activation of hypoxia inducible factor 1 transcriptional activity in cells subjected to intermittent hypoxia
    • Yuan G, Nanduri J, Bhasker CR, Semenza GL, Prabhakar NR. 2005. Ca2+/calmodulin kinase-dependent activation of hypoxia inducible factor 1 transcriptional activity in cells subjected to intermittent hypoxia. J Biol Chem 280:4321-8.
    • (2005) J Biol Chem , vol.280 , pp. 4321-4328
    • Yuan, G.1    Nanduri, J.2    Bhasker, C.R.3    Semenza, G.L.4    Prabhakar, N.R.5
  • 62
    • 19644367000 scopus 로고    scopus 로고
    • Activation and signaling of the p38 MAP kinase pathway
    • Zarubin T, Han J. 2005. Activation and signaling of the p38 MAP kinase pathway. Cell Res 15:11-18.
    • (2005) Cell Res , vol.15 , pp. 11-18
    • Zarubin, T.1    Han, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.