Effect of p47phox gene deletion on ROS production and oxygen sensing in mouse carotid body chemoreceptor cells

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 289, Issue 6 33-6, 2005, Pages

  He, L ^a   Dinger, B ^a   Sanders, K ^a   Hoidal, J ^a   Obeso, A ^b   Stensaas, L ^a   Fidone, S ^a   Gonzalez, C ^b  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b Universidad de Valladolid y Consejo Superior de Investigaciones Científicas   (Spain)

Author keywords

Cell calcium; Cellular redox; Dihydroethidium; Potassium channels; Reactive oxygen species

Indexed keywords

4 (2 AMINOETHYL)BENZENESULFONYL FLUORIDE; ARACHIDONIC ACID; AZIDE; CALCIUM ION; CHEMOTACTIC PEPTIDE; CYTOCHALASIN B; DYE; ENZYME INHIBITOR; FORMYLMETHIONYLLEUCYLPHENYLALANINE; HYDROETHIDINE; OXYGEN; POTASSIUM CHANNEL; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; 4 2(AMINOETHYL) BENZENSULFONYL FLUORIDE; 4-2(AMINOETHYL)-BENZENSULFONYL FLUORIDE; CALCIUM; CATION; DIPHENYLIODONIUM SALT; NEUTROPHIL CYTOSOLIC FACTOR 1; PHOSPHOPROTEIN; POTASSIUM; SODIUM AZIDE; SULFONE; VOLTAGE GATED POTASSIUM CHANNEL;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CAROTID BODY; CAROTID BODY CHEMORECEPTOR; CONTROLLED STUDY; FLUORESCENCE; GENE; GENE DELETION; HYPOTHESIS; HYPOXIA; MEMBRANE POTENTIAL; METHODOLOGY; MITOCHONDRION; MOUSE; NEUTROPHIL; NONHUMAN; OXIDATION REDUCTION REACTION; P47PHOX GENE; PRIORITY JOURNAL; SYMPATHETIC NERVE CELL; ANIMAL; CELL CULTURE; CELL HYPOXIA; CELL MEMBRANE POTENTIAL; CYTOLOGY; DRUG EFFECT; GENETICS; ION TRANSPORT; METABOLISM; MOUSE MUTANT; NEUTROPHIL CHEMOTAXIS; PATCH CLAMP; PHYSIOLOGY;

ANIMALS; ARACHIDONIC ACID; CALCIUM; CAROTID BODY; CELL HYPOXIA; CELLS, CULTURED; CHEMOTAXIS, LEUKOCYTE; ENZYME INHIBITORS; GENE DELETION; ION TRANSPORT; MEMBRANE POTENTIALS; MICE; MICE, KNOCKOUT; MITOCHONDRIA; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; NADPH OXIDASE; NEUTROPHILS; ONIUM COMPOUNDS; OXYGEN; PATCH-CLAMP TECHNIQUES; PHOSPHOPROTEINS; POTASSIUM; POTASSIUM CHANNELS, VOLTAGE-GATED; REACTIVE OXYGEN SPECIES; SODIUM AZIDE; SULFONES;

EID: 27944494427     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.00015.2005     Document Type: Article

References (51)

1. Acker H. Mechanisms and meaning of cellular oxygen sensing in the organism. Respir Physiol 95: 1-10, 1994.
2. 2 chemoreception. J Auton Nerv Syst 41: 41-51, 1992.
3. Boyum A. Separation of white blood cells. Nature 204: 793-794, 1964.
4. Bright GR, Agani FH, Haque U, Overhold JL, and Prabhakar NR. Heterogeneity in cytosolic calcium responses to hypoxia in carotid body cells. Brain Res 706: 297-302, 1996.
5. Buckler KJ. A novel oxygen-sensitive potassium current in rat carotid body type I cells. J Physiol 498: 649-666, 1997.
6. +-currents and oxygen sensing in carotid body type 1 cells. Respir Physiol 115: 179-187, 1999.
7. Buckler KJ, Williams BA, and Honore E. An oxygen-, acid- and anaesthetic-sensitive TASK-like background potassium channel in rat arterial chemoreceptor cells. J Physiol 525: 135-142, 2000.
8. O2 measurements in denervated cat carotid body. J Appl Physiol 67: 1578-1584, 1989.
9. Bunn HF, Gu J, Huang E, Park JW, and Zhu H. Erythropoietin: a model system for studying oxygen-dependent gene regulation. J Exp Biol 201: 1197-1201, 1998.
10. Cachero TG, Rigual R, Rocher A, and Gonzalez C. Cholera and pertussis toxins reveal multiple regulation of cAMP levels in the rabbit carotid body. Eur J Neurosci 8: 2320-2327, 1996.
11. Chandel NS, Maltepe E, Goldwasser E, Mathieu CE, Simon MC, and Schumacker PT. Mitochondrial reactive oxygen species trigger hypoxia-induced transcription. Proc Natl Acad Sci USA 95: 11715-11720, 1998.
12. Chandel NS and Schumacker PT. Cellular oxygen sensing by mitochondria: old questions, new insight. J Appl Physiol 88: 1880-1889, 2000.
13. phox: cloning and tissue expression of Nox3, Nox4 and Nox5. Gene 269: 131-140, 2001.
14. 2 sensor protein in the rat carotid body. Biochem J 272: 743-747, 1990.
15. Cross AR and Jones OTG. The effect of the inhibitor diphenylene iodonium on the superoxide-generating system of neutrophils. Biochem J 237: 111-116, 1986.
16. Diatchuk V, Lotan O, Koshkin V, Wikstroem P, and Pick E. Inhibition of NADPH oxidase activation by 4-(2-aminoethyl)-benzenesulfonyl fluoride and related compounds. J Biol Chem 272: 13292-13301, 1997.
17. + channels essential for carotid body chemo-transduction? Respir Physiol 110: 211-218, 1997.
18. 558 large subunit immunoreactivity. Neuroreport 10: 2615-2617, 1999.
19. Fidone S, Dinger BG, and Gonzalez C. Mechanisms of carotid body chemoreception. In: The Lung Biology in Health Disease. The Regulation of Breathing, edited by Dempsey JA and Pack AI. New York: Dekker, 1995, vol. X, p. 391-471.
20. Fidone SJ, Gonzalez C, Almaraz L, and Dinger B. Cellular mechanisms of peripheral chemoreceptor function. In: The Lung: Scientific Foundations, edited by Crystal RG and West JB, Barnes PJ, and Weibel ER. Philadelphia, PA: Lippincott-Raven, 1997, p. 1725-1746.
21. + current modulation in wild-type and oxidase-deficient mice. Proc Natl Acad Sci USA 97: 4374-4379, 2000.
22. Galvez A, Gimenez-Gallego G, Reuben JP, Roy-Contancin L, Feigenbaum P, Kaczorowski GJ, and Garcia ML. Purification and characterization of a unique, potent, peptidyl probe for the high conductance calcium-activated potassium channel from venom of the scorpion Buthus tamulus. J Biol Chem 265: 11083-11090, 1990.
23. Gonzalez C, Almaraz L, Obeso A, and Rigual R. Carotid body chemoreceptors: from natural stimuli to sensory discharges. Physiol Rev 74: 829-898, 1994.
24. Griendling KK, Sorescu D, and Ushio-Fukai M. NAD(P)H oxidase: role in cardiovascular biology and disease. Circ Res 86: 494-501, 2000.
25. He L, Chen J, Dinger B, Sanders K, Sundar K, Hoidal J, and Fidone S. Characteristics of carotid body chemosensitivity in NADPH oxidase-deficient mice. Am J Physiol Cell Physiol 282: C27-C33, 2002.
26. He L, Dinger B, and Fidone S. Cellular mechanisms involved in carotid body inhibition produced by atrial natriuretic peptide. Am J Physiol Cell Physiol 278: C845-C852, 2000.
27. 2 chemosensitivity. Blood 99: 1552-1555, 2002.
28. 2 in mammalian cells. Proc Natl Acad Sci USA 96: 6255-6260, 1999.
29. phox mouse knock-out model of chronic granulomatous disease. J Exp Med 182: 751-758, 1995.
30. i of rat glomus cells. Brain Res 995: 285-296, 2004.
31. 2 radicals in intact hearts with ischemia and reperfusion. Am J Physiol Heart Circ Physiol 284: H566-H574, 2003.
32. Kummer W and Acker H. Immunohistochemical demonstration of four subunits of neutrophil NAD(P)H oxidase in type I cells of carotid body. J Appl Physiol 78: 1904-1909, 1995.
33. + current inhibition by low oxygen in chemoreceptor cells of adult rabbit carotid body: effects of carbon monoxide. FEBS Lett 299: 251-254, 1992.
34. 2 sensing by airway chemoreceptor-derived cells: protein kinase C activation reveals functional evidence for involvement of NADPH oxidase. J Biol Chem 275: 7684-7692, 2000.
35. 2 transduction in rat and rabbit CB chemoreceptor cells. Am J Physiol Cell Physiol 276: C593-C601, 1999.
36. 2 on glucose uptake in rabbit carotid body. J Appl Physiol 74: 2387-2393, 1993.
37. +-channel blockers. Respir Physiol Neurobiol 132: 69-79, 2002.
38. Patel AJ and Honoré E. Molecular physiology of oxygen-sensitive potassium channels. Eur Respir J 18: 221-227, 2001.
39. + current. Neurosci Lett 119: 253-256, 1990.
40. Peers C and Buckler KJ. Transduction of chemostimuli by the type I carotid body cell. J Membr Biol 144: 1-9, 1995.
41. 2 sensitivity to Kv4.2 but not to Shaker channels. J Gen Physiol 113: 897-907, 1999.
42. Pérez-Garcia MT, Obeso A, López-López JR, Herreros B, and Gonzalez C. Characterization of cultured chemoreceptor cells dissociated from adult rabbit carotid body. Am J Physiol Cell Physiol 263: C1152-C1159, 1992.
43. Prabhakar NR. Oxygen sensing by the carotid body chemoreceptors. J Appl Physiol 88: 2287-2295, 2000.
44. + channels of rat chemoreceptor cells by a membrane-restricted and CO-sensitive mechanism. Circ Res 89: 430-436, 2001.
45. Sanders KA, Sundar KM, He L, Dinger B, Fidone S, and Hoidal JR. Role of components of the phagocytic NADPH oxidase in oxygen sensing. J Appl Physiol 93: 1357-1364, 2002.
46. Sanz-Alfayate G, Obeso A, Agapito MT, and Gonzalez C. Reduced to oxidized glutathione ratios and oxygen sensing in calf and rabbit carotid body chemoreceptor cells. J Physiol 537: 209-220, 2001.
47. Tarpey MM and Fridovich I. Methods of detection of vascular reactive species: nitric oxide, superoxide, hydrogen peroxide and peroxynitrite. Circ Res 89: 224-236, 2001.
48. Weir EK and Archer SL. The mechanism of acute hypoxic pulmonary vasoconstriction: the tale of two channels. FASEB J 9: 183-189, 1995.
49. Williams SE, Wootton P, Mason HS, Bould J, Iles DE, Riccardi D, Peers C, and Kemp PJ. Hemoxygenase-2 is an oxygen sensor for a calcium-sensitive potassium channel. Science 306: 2093-2097, 2004.
50. + channels in isolated type I cells of the neonatal rat carotid body. J Physiol 483: 559-565, 1995.
51. Youngson C, Nurse C, Yeger H, and Cutz E. Oxygen sensing in airway chemoreceptors. Nature 365: 153-155, 1993.