Investigating the structural impacts of I64T and P311S mutations in APE1-DNA complex: A molecular dynamics approach

PLoS ONE

Volumn 7, Issue 2, 2012, Pages

  Doss, C George Priya ^a   NagaSundaram, N ^a  

^a VIT UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; APEX1 PROTEIN, HUMAN; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE;

APE1 GENE; ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; DISEASE PREDISPOSITION; DNA PROTEIN COMPLEX; GENE MUTATION; GENE PRODUCT; GENETIC ASSOCIATION; GENETIC STABILITY; GENETIC VARIABILITY; HUMAN; HYDROGEN BOND; MOLECULAR DYNAMICS; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN STABILITY; PROTEIN STRUCTURE; SINGLE NUCLEOTIDE POLYMORPHISM; STRUCTURE ANALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DNA REPAIR; GENE DELETION; GENETICS; GENOMICS; MUTATION;

DNA; DNA REPAIR; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; GENE DELETION; GENETIC VARIATION; GENOMICS; HUMANS; HYDROGEN BONDING; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR DYNAMICS SIMULATION; MUTATION; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN CONFORMATION;

EID: 84857566949     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0031677     Document Type: Article

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