-
1
-
-
84960987950
-
The concentration of oxygen dissolved in tissues at the time of irradiation as a factor in radiotherapy
-
Gray L.H., Conger A.D., Ebert M., et al. The concentration of oxygen dissolved in tissues at the time of irradiation as a factor in radiotherapy. Br J Radiol 1953, 26:638-648.
-
(1953)
Br J Radiol
, vol.26
, pp. 638-648
-
-
Gray, L.H.1
Conger, A.D.2
Ebert, M.3
-
2
-
-
0038523737
-
Tumor hypoxia at the micro-regional level: Clinical relevance and predictive value of exogenous and endogenous hypoxic cell markers
-
Bussink J., Kaanders J.H., van der Kogel A.J. Tumor hypoxia at the micro-regional level: Clinical relevance and predictive value of exogenous and endogenous hypoxic cell markers. Radiother Oncol 2003, 67:3-15.
-
(2003)
Radiother Oncol
, vol.67
, pp. 3-15
-
-
Bussink, J.1
Kaanders, J.H.2
van der Kogel, A.J.3
-
3
-
-
34748860952
-
Hypoxic radiosensitization: Adored and ignored
-
Overgaard J. Hypoxic radiosensitization: Adored and ignored. J Clin Oncol 2007, 25:4066-4074.
-
(2007)
J Clin Oncol
, vol.25
, pp. 4066-4074
-
-
Overgaard, J.1
-
4
-
-
77954612304
-
More lessons learned from the suffocation of hypoxia
-
Ang K.K. More lessons learned from the suffocation of hypoxia. J Clin Oncol 2010, 28:2941-2943.
-
(2010)
J Clin Oncol
, vol.28
, pp. 2941-2943
-
-
Ang, K.K.1
-
5
-
-
80051795366
-
Outcome after ARCON for clinical stage T2-4 laryngeal cancer: Early results of a phase III randomized trial
-
Kaanders J.H., Terhaard C., Doornaert P., et al. Outcome after ARCON for clinical stage T2-4 laryngeal cancer: Early results of a phase III randomized trial. Radiother Oncol 2010, 96:158.
-
(2010)
Radiother Oncol
, vol.96
, pp. 158
-
-
Kaanders, J.H.1
Terhaard, C.2
Doornaert, P.3
-
6
-
-
0031909654
-
A randomized double-blind phase III study of nimorazole as a hypoxic radiosensitizer of primary radiotherapy in supraglottic larynx and pharynx carcinoma. Results of the Danish Head and Neck Cancer Study (DAHANCA) Protocol 5-85
-
Overgaard J., Hansen H.S., Overgaard M., et al. A randomized double-blind phase III study of nimorazole as a hypoxic radiosensitizer of primary radiotherapy in supraglottic larynx and pharynx carcinoma. Results of the Danish Head and Neck Cancer Study (DAHANCA) Protocol 5-85. Radiother Oncol 1998, 46:135-146.
-
(1998)
Radiother Oncol
, vol.46
, pp. 135-146
-
-
Overgaard, J.1
Hansen, H.S.2
Overgaard, M.3
-
7
-
-
77954600498
-
Tirapazamine, cisplatin, and radiation versus cisplatin and radiation for advanced squamous cell carcinoma of the head and neck (TROG 02.02, HeadSTART): A phase III trial of the Trans-Tasman Radiation Oncology Group
-
Rischin D., Peters L.J., O'Sullivan B., et al. Tirapazamine, cisplatin, and radiation versus cisplatin and radiation for advanced squamous cell carcinoma of the head and neck (TROG 02.02, HeadSTART): A phase III trial of the Trans-Tasman Radiation Oncology Group. J Clin Oncol 2010, 28:2989-2995.
-
(2010)
J Clin Oncol
, vol.28
, pp. 2989-2995
-
-
Rischin, D.1
Peters, L.J.2
O'Sullivan, B.3
-
8
-
-
79960344338
-
Hypoxic modification of radiotherapy in squamous cell carcinoma of the head and neck-A systematic review and meta-analysis
-
Overgaard J. Hypoxic modification of radiotherapy in squamous cell carcinoma of the head and neck-A systematic review and meta-analysis. Radiother Oncol 2011, 100:22-32.
-
(2011)
Radiother Oncol
, vol.100
, pp. 22-32
-
-
Overgaard, J.1
-
9
-
-
0027288316
-
SR 4233 (tirapazamine): A new anticancer drug exploiting hypoxia in solid tumours
-
Brown J.M. SR 4233 (tirapazamine): A new anticancer drug exploiting hypoxia in solid tumours. Br J Cancer 1993, 67:1163-1170.
-
(1993)
Br J Cancer
, vol.67
, pp. 1163-1170
-
-
Brown, J.M.1
-
10
-
-
0033405294
-
The hypoxic cell: A target for selective cancer therapy-Eighteenth Bruce F. Cain memorial award lecture
-
Brown J.M. The hypoxic cell: A target for selective cancer therapy-Eighteenth Bruce F. Cain memorial award lecture. Cancer Res 1999, 59:5863-5870.
-
(1999)
Cancer Res
, vol.59
, pp. 5863-5870
-
-
Brown, J.M.1
-
12
-
-
0036498885
-
ARCON: Experience in 215 patients with advanced head-and-neck cancer
-
Kaanders J.H., Pop L.A., Marres H.A., et al. ARCON: Experience in 215 patients with advanced head-and-neck cancer. Int J Radiat Oncol Biol Phys 2002, 52:769-778.
-
(2002)
Int J Radiat Oncol Biol Phys
, vol.52
, pp. 769-778
-
-
Kaanders, J.H.1
Pop, L.A.2
Marres, H.A.3
-
13
-
-
33646454133
-
Prognostic significance of [18F]-misonidazole positron emission tomography-detected tumor hypoxia in patients with advanced head and neck cancer randomly assigned to chemoradiation with or without tirapazamine: A substudy of Trans-Tasman Radiation Oncology Group study 98.02
-
Rischin D., Hicks R.J., Fisher R., et al. Prognostic significance of [18F]-misonidazole positron emission tomography-detected tumor hypoxia in patients with advanced head and neck cancer randomly assigned to chemoradiation with or without tirapazamine: A substudy of Trans-Tasman Radiation Oncology Group study 98.02. J Clin Oncol 2006, 24:2098-2104.
-
(2006)
J Clin Oncol
, vol.24
, pp. 2098-2104
-
-
Rischin, D.1
Hicks, R.J.2
Fisher, R.3
-
14
-
-
0036896722
-
Pimonidazole binding and tumor vascularity predict for treatment outcome in head and neck cancer
-
Kaanders J.H., Wijffels K.I., Marres H.A., et al. Pimonidazole binding and tumor vascularity predict for treatment outcome in head and neck cancer. Cancer Res 2002, 62:7066-7074.
-
(2002)
Cancer Res
, vol.62
, pp. 7066-7074
-
-
Kaanders, J.H.1
Wijffels, K.I.2
Marres, H.A.3
-
15
-
-
40949155534
-
Patterns and levels of hypoxia in head and neck squamous cell carcinomas and their relationship to patient outcome: In regard to Evans et al. (Int J Radiat Oncol Biol Phys 69:1024-1031, 2007)
-
Bussink J., van der Kogel A.J., Kaanders J.H. Patterns and levels of hypoxia in head and neck squamous cell carcinomas and their relationship to patient outcome: In regard to Evans et al. (Int J Radiat Oncol Biol Phys 69:1024-1031, 2007). Int J Radiat Oncol Biol Phys 2008, 70:1616.
-
(2008)
Int J Radiat Oncol Biol Phys
, vol.70
, pp. 1616
-
-
Bussink, J.1
van der Kogel, A.J.2
Kaanders, J.H.3
-
16
-
-
84455186420
-
Predictive value of hypoxia-related markers in head and neck cancer treated with ARCON
-
Rademakers S., Hoogsteen I.J., Marres H.A., et al. Predictive value of hypoxia-related markers in head and neck cancer treated with ARCON. Radiother Oncol 2010, 96:77.
-
(2010)
Radiother Oncol
, vol.96
, pp. 77
-
-
Rademakers, S.1
Hoogsteen, I.J.2
Marres, H.A.3
-
17
-
-
47949120077
-
Clinical biomarkers for hypoxia targeting
-
Le Q.T., Courter D. Clinical biomarkers for hypoxia targeting. Cancer Metastasis Rev 2008, 27:351-362.
-
(2008)
Cancer Metastasis Rev
, vol.27
, pp. 351-362
-
-
Le, Q.T.1
Courter, D.2
-
18
-
-
0037377261
-
Estimating hypoxic status in human tumors: A simulation using Eppendorf oxygen probe data in cervical cancer patients
-
Doll C.M., Milosevic M., Pintilie M., et al. Estimating hypoxic status in human tumors: A simulation using Eppendorf oxygen probe data in cervical cancer patients. Int J Radiat Oncol Biol Phys 2003, 55:1239-1246.
-
(2003)
Int J Radiat Oncol Biol Phys
, vol.55
, pp. 1239-1246
-
-
Doll, C.M.1
Milosevic, M.2
Pintilie, M.3
-
19
-
-
0032801526
-
Comparisons among pimonidazole binding, oxygen electrode measurements, and radiation response in C3H mouse tumors
-
Raleigh J.A., Chou S.C., Arteel G.E., et al. Comparisons among pimonidazole binding, oxygen electrode measurements, and radiation response in C3H mouse tumors. Radiat Res 1999, 151:580-589.
-
(1999)
Radiat Res
, vol.151
, pp. 580-589
-
-
Raleigh, J.A.1
Chou, S.C.2
Arteel, G.E.3
-
20
-
-
0029012868
-
Calibration of misonidazole labeling by simultaneous measurement of oxygen tension and labeling density in multicellular spheroids
-
Gross M.W., Karbach U., Groebe K., et al. Calibration of misonidazole labeling by simultaneous measurement of oxygen tension and labeling density in multicellular spheroids. Int J Cancer 1995, 61:567-573.
-
(1995)
Int J Cancer
, vol.61
, pp. 567-573
-
-
Gross, M.W.1
Karbach, U.2
Groebe, K.3
-
21
-
-
58149287834
-
Cellular uptake of PET tracers of glucose metabolism and hypoxia and their linkage
-
Busk M., Horsman M.R., Jakobsen S., et al. Cellular uptake of PET tracers of glucose metabolism and hypoxia and their linkage. Eur J Nucl Med Mol Imaging 2008, 35:2294-2303.
-
(2008)
Eur J Nucl Med Mol Imaging
, vol.35
, pp. 2294-2303
-
-
Busk, M.1
Horsman, M.R.2
Jakobsen, S.3
-
22
-
-
0034029848
-
Detection of hypoxia in human squamous cell carcinoma by EF5 binding
-
Evans S.M., Hahn S., Pook D.R., et al. Detection of hypoxia in human squamous cell carcinoma by EF5 binding. Cancer Res 2000, 60:2018-2024.
-
(2000)
Cancer Res
, vol.60
, pp. 2018-2024
-
-
Evans, S.M.1
Hahn, S.2
Pook, D.R.3
-
23
-
-
69449094645
-
Assessing tumor hypoxia by positron emission tomography with Cu-ATSM
-
Holland J.P., Lewis J.S., Dehdashti F. Assessing tumor hypoxia by positron emission tomography with Cu-ATSM. Q J Nucl Med Mol Imaging 2009, 53:193-200.
-
(2009)
Q J Nucl Med Mol Imaging
, vol.53
, pp. 193-200
-
-
Holland, J.P.1
Lewis, J.S.2
Dehdashti, F.3
-
24
-
-
26444466467
-
Prognostic value of tumor oxygenation in 397 head and neck tumors after primary radiation therapy. An international multi-center study
-
Nordsmark M., Bentzen S.M., Rudat V., et al. Prognostic value of tumor oxygenation in 397 head and neck tumors after primary radiation therapy. An international multi-center study. Radiother Oncol 2005, 77:18-24.
-
(2005)
Radiother Oncol
, vol.77
, pp. 18-24
-
-
Nordsmark, M.1
Bentzen, S.M.2
Rudat, V.3
-
25
-
-
15844368087
-
Prognostic impact of hypoxia imaging with 18F-misonidazole PET in non-small cell lung cancer and head and neck cancer before radiotherapy
-
Eschmann S.M., Paulsen F., Reimold M., et al. Prognostic impact of hypoxia imaging with 18F-misonidazole PET in non-small cell lung cancer and head and neck cancer before radiotherapy. J Nucl Med 2005, 46:253-260.
-
(2005)
J Nucl Med
, vol.46
, pp. 253-260
-
-
Eschmann, S.M.1
Paulsen, F.2
Reimold, M.3
-
26
-
-
34447503754
-
The potential role of intrinsic hypoxia markers as prognostic variables in cancer
-
Moon E.J., Brizel D.M., Chi J.T., et al. The potential role of intrinsic hypoxia markers as prognostic variables in cancer. Antioxid Redox Signal 2007, 9:1237-1294.
-
(2007)
Antioxid Redox Signal
, vol.9
, pp. 1237-1294
-
-
Moon, E.J.1
Brizel, D.M.2
Chi, J.T.3
-
27
-
-
0344667645
-
Endogenous markers of tumor hypoxia predictors of clinical radiation resistance?
-
Vordermark D., Brown J.M. Endogenous markers of tumor hypoxia predictors of clinical radiation resistance?. Strahlenther Onkol 2003, 179:801-811.
-
(2003)
Strahlenther Onkol
, vol.179
, pp. 801-811
-
-
Vordermark, D.1
Brown, J.M.2
-
28
-
-
33746265277
-
The prognostic value of endogenous hypoxia-related markers for head and neck squamous cell carcinomas treated with ARCON
-
Jonathan R.A., Wijffels K.I., Peeters W., et al. The prognostic value of endogenous hypoxia-related markers for head and neck squamous cell carcinomas treated with ARCON. Radiother Oncol 2006, 79:288-297.
-
(2006)
Radiother Oncol
, vol.79
, pp. 288-297
-
-
Jonathan, R.A.1
Wijffels, K.I.2
Peeters, W.3
-
29
-
-
34250166555
-
Differential risk assessments from five hypoxia specific assays: The basis for biologically adapted individualized radiotherapy in advanced head and neck cancer patients
-
Nordsmark M., Eriksen J.G., Gebski V., et al. Differential risk assessments from five hypoxia specific assays: The basis for biologically adapted individualized radiotherapy in advanced head and neck cancer patients. Radiother Oncol 2007, 83:389-397.
-
(2007)
Radiother Oncol
, vol.83
, pp. 389-397
-
-
Nordsmark, M.1
Eriksen, J.G.2
Gebski, V.3
-
30
-
-
34250182435
-
Lack of prognostic and predictive value of ca IX in radiotherapy of squamous cell carcinoma of the head and neck with known modifiable hypoxia: An evaluation of the DAHANCA 5 study
-
Danish Head and Neck Cancer Study Group (DAHANCA)
-
Eriksen J.G., Overgaard J. Lack of prognostic and predictive value of ca IX in radiotherapy of squamous cell carcinoma of the head and neck with known modifiable hypoxia: An evaluation of the DAHANCA 5 study. Radiother Oncol 2007, 83:383-388. Danish Head and Neck Cancer Study Group (DAHANCA).
-
(2007)
Radiother Oncol
, vol.83
, pp. 383-388
-
-
Eriksen, J.G.1
Overgaard, J.2
-
31
-
-
26844468059
-
The prognostic value of the hypoxia markers ca IX and GLUT 1 and the cytokines VEGF and IL 6 in head and neck squamous cell carcinoma treated by radiotherapy +/- chemotherapy
-
De Schutter H., Landuyt W., Verbeken E., et al. The prognostic value of the hypoxia markers ca IX and GLUT 1 and the cytokines VEGF and IL 6 in head and neck squamous cell carcinoma treated by radiotherapy +/- chemotherapy. BMC Cancer 2005, 5:42.
-
(2005)
BMC Cancer
, vol.5
, pp. 42
-
-
De Schutter, H.1
Landuyt, W.2
Verbeken, E.3
-
32
-
-
1242316333
-
Prognostic value of facilitative glucose transporter glut-1 in oral squamous cell carcinomas treated by surgical resection; results of EORTC translational research fund studies
-
Oliver R.J., Woodwards R.T., Sloan P., et al. Prognostic value of facilitative glucose transporter glut-1 in oral squamous cell carcinomas treated by surgical resection; results of EORTC translational research fund studies. Eur J Cancer 2004, 40:503-507.
-
(2004)
Eur J Cancer
, vol.40
, pp. 503-507
-
-
Oliver, R.J.1
Woodwards, R.T.2
Sloan, P.3
-
33
-
-
33646365644
-
Lysyl oxidase is essential for hypoxia-induced metastasis
-
Erler J.T., Bennewith K.L., Nicolau M., et al. Lysyl oxidase is essential for hypoxia-induced metastasis. Nature 2006, 440:1222-1226.
-
(2006)
Nature
, vol.440
, pp. 1222-1226
-
-
Erler, J.T.1
Bennewith, K.L.2
Nicolau, M.3
-
34
-
-
70349307281
-
Validation of lysyl oxidase as a prognostic marker for metastasis and survival in head and neck squamous cell carcinoma: Radiation Therapy Oncology Group trial 90-03
-
Le Q.T., Harris J., Magliocco A.M., et al. Validation of lysyl oxidase as a prognostic marker for metastasis and survival in head and neck squamous cell carcinoma: Radiation Therapy Oncology Group trial 90-03. J Clin Oncol 2009, 27:4281-4286.
-
(2009)
J Clin Oncol
, vol.27
, pp. 4281-4286
-
-
Le, Q.T.1
Harris, J.2
Magliocco, A.M.3
-
35
-
-
12244267969
-
Identification of osteopontin as a prognostic plasma marker for head and neck squamous cell carcinomas
-
Le Q.T., Sutphin P.D., Raychaudhuri S., et al. Identification of osteopontin as a prognostic plasma marker for head and neck squamous cell carcinomas. Clin Cancer Res 2003, 9:59-67.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 59-67
-
-
Le, Q.T.1
Sutphin, P.D.2
Raychaudhuri, S.3
-
36
-
-
34547842084
-
Expression and prognostic significance of a panel of tissue hypoxia markers in head-and-neck squamous cell carcinomas
-
Le Q.T., Kong C., Lavori P.W., et al. Expression and prognostic significance of a panel of tissue hypoxia markers in head-and-neck squamous cell carcinomas. Int J Radiat Oncol Biol Phys 2007, 69:167-175.
-
(2007)
Int J Radiat Oncol Biol Phys
, vol.69
, pp. 167-175
-
-
Le, Q.T.1
Kong, C.2
Lavori, P.W.3
-
37
-
-
26444467146
-
Plasma osteopontin, hypoxia, and response to the hypoxia sensitiser nimorazole in radiotherapy of head and neck cancer: Results from the DAHANCA 5 randomised double-blind placebo-controlled trial
-
Overgaard J., Eriksen J.G., Nordsmark M., et al. Plasma osteopontin, hypoxia, and response to the hypoxia sensitiser nimorazole in radiotherapy of head and neck cancer: Results from the DAHANCA 5 randomised double-blind placebo-controlled trial. Lancet Oncol 2005, 6:757-764.
-
(2005)
Lancet Oncol
, vol.6
, pp. 757-764
-
-
Overgaard, J.1
Eriksen, J.G.2
Nordsmark, M.3
-
38
-
-
76049100577
-
HIF-1: Upstream and downstream of cancer metabolism
-
Semenza G.L. HIF-1: Upstream and downstream of cancer metabolism. Curr Opin Genet Dev 2010, 20:51-56.
-
(2010)
Curr Opin Genet Dev
, vol.20
, pp. 51-56
-
-
Semenza, G.L.1
-
40
-
-
0142166332
-
Targeting HIF-1 for cancer therapy
-
Semenza G.L. Targeting HIF-1 for cancer therapy. Nat Rev Cancer 2003, 3:721-732.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 721-732
-
-
Semenza, G.L.1
-
41
-
-
0036883983
-
HIF-1A, pimonidazole, and iododeoxyuridine to estimate hypoxia and perfusion in human head-and-neck tumors
-
Janssen H.L., Haustermans K.M., Sprong D., et al. HIF-1A, pimonidazole, and iododeoxyuridine to estimate hypoxia and perfusion in human head-and-neck tumors. Int J Radiat Oncol Biol Phys 2002, 54:1537-1549.
-
(2002)
Int J Radiat Oncol Biol Phys
, vol.54
, pp. 1537-1549
-
-
Janssen, H.L.1
Haustermans, K.M.2
Sprong, D.3
-
42
-
-
19944429962
-
Hypoxia-inducible factor 1alpha expression as an intrinsic marker of hypoxia: Correlation with tumor oxygen, pimonidazole measurements, and outcome in locally advanced carcinoma of the cervix
-
Hutchison G.J., Valentine H.R., Loncaster J.A., et al. Hypoxia-inducible factor 1alpha expression as an intrinsic marker of hypoxia: Correlation with tumor oxygen, pimonidazole measurements, and outcome in locally advanced carcinoma of the cervix. Clin Cancer Res 2004, 10:8405-8412.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 8405-8412
-
-
Hutchison, G.J.1
Valentine, H.R.2
Loncaster, J.A.3
-
43
-
-
33744954065
-
Concordant regulation of gene expression by hypoxia and 2-oxoglutarate-dependent dioxygenase inhibition: The role of HIF-1alpha, HIF-2alpha, and other pathways
-
Elvidge G.P., Glenny L., Appelhoff R.J., et al. Concordant regulation of gene expression by hypoxia and 2-oxoglutarate-dependent dioxygenase inhibition: The role of HIF-1alpha, HIF-2alpha, and other pathways. J Biol Chem 2006, 281:15215-15226.
-
(2006)
J Biol Chem
, vol.281
, pp. 15215-15226
-
-
Elvidge, G.P.1
Glenny, L.2
Appelhoff, R.J.3
-
44
-
-
79551542410
-
In vivo profiling of hypoxic Gene expression in gliomas using the hypoxia marker EF5 and laser-capture microdissection
-
Marotta D., Karar J., Jenkins W.T., et al. In vivo profiling of hypoxic Gene expression in gliomas using the hypoxia marker EF5 and laser-capture microdissection. Cancer Res 2011, 71:779-789.
-
(2011)
Cancer Res
, vol.71
, pp. 779-789
-
-
Marotta, D.1
Karar, J.2
Jenkins, W.T.3
-
45
-
-
33644551073
-
Gene expression programs in response to hypoxia: Cell type specificity and prognostic significance in human cancers
-
Chi J.T., Wang Z., Nuyten D.S., et al. Gene expression programs in response to hypoxia: Cell type specificity and prognostic significance in human cancers. PLoS Med 2006, 3:e47.
-
(2006)
PLoS Med
, vol.3
-
-
Chi, J.T.1
Wang, Z.2
Nuyten, D.S.3
-
46
-
-
34248172298
-
Relation of a hypoxia metagene derived from head and neck cancer to prognosis of multiple cancers
-
Winter S.C., Buffa F.M., Silva P., et al. Relation of a hypoxia metagene derived from head and neck cancer to prognosis of multiple cancers. Cancer Res 2007, 67:3441-3449.
-
(2007)
Cancer Res
, vol.67
, pp. 3441-3449
-
-
Winter, S.C.1
Buffa, F.M.2
Silva, P.3
-
47
-
-
75649117850
-
Large meta-analysis of multiple cancers reveals a common, compact and highly prognostic hypoxia metagene
-
Buffa F.M., Harris A.L., West C.M., et al. Large meta-analysis of multiple cancers reveals a common, compact and highly prognostic hypoxia metagene. Br J Cancer 2010, 102:428-435.
-
(2010)
Br J Cancer
, vol.102
, pp. 428-435
-
-
Buffa, F.M.1
Harris, A.L.2
West, C.M.3
-
48
-
-
0141869070
-
Investigating hypoxic tumor physiology through gene expression patterns
-
Denko N.C., Fontana L.A., Hudson K.M., et al. Investigating hypoxic tumor physiology through gene expression patterns. Oncogene 2003, 22:5907-5914.
-
(2003)
Oncogene
, vol.22
, pp. 5907-5914
-
-
Denko, N.C.1
Fontana, L.A.2
Hudson, K.M.3
-
49
-
-
34250323878
-
Impact of supervised gene signatures of early hypoxia on patient survival
-
Seigneuric R., Starmans M.H., Fung G., et al. Impact of supervised gene signatures of early hypoxia on patient survival. Radiother Oncol 2007, 83:374-382.
-
(2007)
Radiother Oncol
, vol.83
, pp. 374-382
-
-
Seigneuric, R.1
Starmans, M.H.2
Fung, G.3
-
50
-
-
80051794223
-
Development of a hypoxia gene expression classifier with predictive impact for hypoxic modification of radiotherapy in head and neck cancer
-
Toustrup K., Sørensen B.S., Nordsmark M., et al. Development of a hypoxia gene expression classifier with predictive impact for hypoxic modification of radiotherapy in head and neck cancer. Cancer Res 2011, 71:5923-5931.
-
(2011)
Cancer Res
, vol.71
, pp. 5923-5931
-
-
Toustrup, K.1
Sørensen, B.S.2
Nordsmark, M.3
-
51
-
-
77956587695
-
Identifying pH independent hypoxia induced genes in human squamous cell carcinomas in vitro
-
Sørensen B.S., Toustrup K., Horsman M.R., et al. Identifying pH independent hypoxia induced genes in human squamous cell carcinomas in vitro. Acta Oncol 2010, 49:895-905.
-
(2010)
Acta Oncol
, vol.49
, pp. 895-905
-
-
Sørensen, B.S.1
Toustrup, K.2
Horsman, M.R.3
-
52
-
-
0029955072
-
Pretreatment oxygenation predicts radiation response in advanced squamous cell carcinoma of the head and neck
-
Nordsmark M., Overgaard M., Overgaard J. Pretreatment oxygenation predicts radiation response in advanced squamous cell carcinoma of the head and neck. Radiother Oncol 1996, 41:31-39.
-
(1996)
Radiother Oncol
, vol.41
, pp. 31-39
-
-
Nordsmark, M.1
Overgaard, M.2
Overgaard, J.3
-
53
-
-
0034307112
-
A confirmatory prognostic study on oxygenation status and loco-regional control in advanced head and neck squamous cell carcinoma treated by radiation therapy
-
Nordsmark M., Overgaard J. A confirmatory prognostic study on oxygenation status and loco-regional control in advanced head and neck squamous cell carcinoma treated by radiation therapy. Radiother Oncol 2000, 57:39-43.
-
(2000)
Radiother Oncol
, vol.57
, pp. 39-43
-
-
Nordsmark, M.1
Overgaard, J.2
-
54
-
-
26444471270
-
Influence of oxygen concentration and pH on expression of hypoxia induced genes
-
Sørensen B.S., Hao J., Overgaard J., et al. Influence of oxygen concentration and pH on expression of hypoxia induced genes. Radiother Oncol 2005, 76:187-193.
-
(2005)
Radiother Oncol
, vol.76
, pp. 187-193
-
-
Sørensen, B.S.1
Hao, J.2
Overgaard, J.3
-
55
-
-
84455209531
-
Gene expression classifier predicts for hypoxic modification of radiotherapy with nimorazole in squamous cell carcinomas of the head and neck
-
Toustrup K., Sørensen B.S., Lassen P., et al. Gene expression classifier predicts for hypoxic modification of radiotherapy with nimorazole in squamous cell carcinomas of the head and neck. Radiother Oncol 2012, 102(1):122-129.
-
(2012)
Radiother Oncol
, vol.102
, Issue.1
, pp. 122-129
-
-
Toustrup, K.1
Sørensen, B.S.2
Lassen, P.3
-
56
-
-
65349173893
-
Effect of HPV-associated p16INK4A expression on response to radiotherapy and survival in squamous cell carcinoma of the head and neck
-
Lassen P., Eriksen J.G., Hamilton-Dutoit S., et al. Effect of HPV-associated p16INK4A expression on response to radiotherapy and survival in squamous cell carcinoma of the head and neck. J Clin Oncol 2009, 27:1992-1998.
-
(2009)
J Clin Oncol
, vol.27
, pp. 1992-1998
-
-
Lassen, P.1
Eriksen, J.G.2
Hamilton-Dutoit, S.3
-
57
-
-
74549123751
-
HPV-associated p16-expression and response to hypoxic modification of radiotherapy in head and neck cancer
-
Lassen P., Eriksen J.G., Hamilton-Dutoit S., et al. HPV-associated p16-expression and response to hypoxic modification of radiotherapy in head and neck cancer. Radiother Oncol 2010, 94:30-35.
-
(2010)
Radiother Oncol
, vol.94
, pp. 30-35
-
-
Lassen, P.1
Eriksen, J.G.2
Hamilton-Dutoit, S.3
-
58
-
-
65449131740
-
The relationship between human papillomavirus status and other molecular prognostic markers in head and neck squamous cell carcinomas
-
Kong C.S., Narasimhan B., Cao H., et al. The relationship between human papillomavirus status and other molecular prognostic markers in head and neck squamous cell carcinomas. Int J Radiat Oncol Biol Phys 2009, 74:553-561.
-
(2009)
Int J Radiat Oncol Biol Phys
, vol.74
, pp. 553-561
-
-
Kong, C.S.1
Narasimhan, B.2
Cao, H.3
-
59
-
-
64749093574
-
Association of reactive oxygen species levels and radioresistance in cancer stem cells
-
Diehn M., Cho R.W., Lobo N.A., et al. Association of reactive oxygen species levels and radioresistance in cancer stem cells. Nature 2009, 458:780-783.
-
(2009)
Nature
, vol.458
, pp. 780-783
-
-
Diehn, M.1
Cho, R.W.2
Lobo, N.A.3
-
60
-
-
45849089879
-
Exploring the role of cancer stem cells in radioresistance
-
Baumann M., Krause M., Hill R. Exploring the role of cancer stem cells in radioresistance. Nat Rev Cancer 2008, 8:545-554.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 545-554
-
-
Baumann, M.1
Krause, M.2
Hill, R.3
-
61
-
-
69549108768
-
RNA extraction from archival formalin-fixed paraffin-embedded tissue: A comparison of manual, semiautomated, and fully automated purification methods
-
Bohmann K., Hennig G., Rogel U., et al. RNA extraction from archival formalin-fixed paraffin-embedded tissue: A comparison of manual, semiautomated, and fully automated purification methods. Clin Chem 2009, 55:1719-1727.
-
(2009)
Clin Chem
, vol.55
, pp. 1719-1727
-
-
Bohmann, K.1
Hennig, G.2
Rogel, U.3
-
62
-
-
78649897310
-
Automated extraction of DNA and RNA from a single formalin-fixed paraffin-embedded tissue section for analysis of both single-nucleotide polymorphisms and mRNA expression
-
Hennig G., Gehrmann M., Stropp U., et al. Automated extraction of DNA and RNA from a single formalin-fixed paraffin-embedded tissue section for analysis of both single-nucleotide polymorphisms and mRNA expression. Clin Chem 2010, 56:1845-1853.
-
(2010)
Clin Chem
, vol.56
, pp. 1845-1853
-
-
Hennig, G.1
Gehrmann, M.2
Stropp, U.3
-
63
-
-
0024207211
-
Effect of cancer chemotherapy on the hypoxic fraction of a solid tumor measured using a local tumor control assay
-
Grau C., Overgaard J. Effect of cancer chemotherapy on the hypoxic fraction of a solid tumor measured using a local tumor control assay. Radiother Oncol 1988, 13:301-309.
-
(1988)
Radiother Oncol
, vol.13
, pp. 301-309
-
-
Grau, C.1
Overgaard, J.2
-
64
-
-
0344127560
-
Gene expression patterns in renal cell carcinoma assessed by complementary DNA microarray
-
Higgins J.P., Shinghal R., Gill H., et al. Gene expression patterns in renal cell carcinoma assessed by complementary DNA microarray. Am J Pathol 2003, 162:925-932.
-
(2003)
Am J Pathol
, vol.162
, pp. 925-932
-
-
Higgins, J.P.1
Shinghal, R.2
Gill, H.3
-
65
-
-
0035845511
-
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
-
Sørlie T., Perou C.M., Tibshirani R., et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci USA 2001, 98:10869-10874.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 10869-10874
-
-
Sørlie, T.1
Perou, C.M.2
Tibshirani, R.3
-
66
-
-
0037137519
-
A gene expression signature as a predictor of survival in breast cancer
-
van de Vijver M.J., He Y.D., vanD́t Veer L.J., et al. A gene expression signature as a predictor of survival in breast cancer. N Eng J Med 2002, 347:1999-2009.
-
(2002)
N Eng J Med
, vol.347
, pp. 1999-2009
-
-
van de Vijver, M.J.1
He, Y.D.2
vand́t Veer, L.J.3
-
67
-
-
26444546442
-
An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival
-
Miller L.D., Smeds J., George J., et al. An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival. Proc Natl Acad Sci USA 2005, 102:13550-13555.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 13550-13555
-
-
Miller, L.D.1
Smeds, J.2
George, J.3
-
68
-
-
2342492313
-
Molecular classification of head and neck squamous cell carcinomas using patterns of gene expression
-
Chung C.H., Parker J.S., Karaca G., et al. Molecular classification of head and neck squamous cell carcinomas using patterns of gene expression. Cancer Cell 2004, 5:489-500.
-
(2004)
Cancer Cell
, vol.5
, pp. 489-500
-
-
Chung, C.H.1
Parker, J.S.2
Karaca, G.3
-
69
-
-
11144354901
-
Identification of genes associated with tumorigenesis and metastatic potential of hyopharyngeal cancer by microarray analysis
-
Cromer A., Carles A., Millon R., et al. Identification of genes associated with tumorigenesis and metastatic potential of hyopharyngeal cancer by microarray analysis. Oncogene 2004, 23:2484-2498.
-
(2004)
Oncogene
, vol.23
, pp. 2484-2498
-
-
Cromer, A.1
Carles, A.2
Millon, R.3
-
70
-
-
34250311964
-
Fundamental differences in cell cycle deregulation in human papillomavirus-positive and human papillomavirus-negative head/neck and cervical cancers
-
Peyon D., Newton M.A., Lambert P.F., et al. Fundamental differences in cell cycle deregulation in human papillomavirus-positive and human papillomavirus-negative head/neck and cervical cancers. Cancer Res 2007, 67:4605-4619.
-
(2007)
Cancer Res
, vol.67
, pp. 4605-4619
-
-
Peyon, D.1
Newton, M.A.2
Lambert, P.F.3
-
71
-
-
44949121510
-
Predicting prognosis using molecular profiling in estrogen receptor positive breast cancer treated with tamoxifen
-
Loi S., Haibe-Kains B., Desmedt C., et al. Predicting prognosis using molecular profiling in estrogen receptor positive breast cancer treated with tamoxifen. BMC genomics 2008, 9:239.
-
(2008)
BMC genomics
, vol.9
, pp. 239
-
-
Loi, S.1
Haibe-Kains, B.2
Desmedt, C.3
-
72
-
-
33750442923
-
Genome-wide analysis of estrogen receptor binding sites
-
Carroll J.S., Meyer C.A., Song J., et al. Genome-wide analysis of estrogen receptor binding sites. Nat Genet 2006, 38:1289-1297.
-
(2006)
Nat Genet
, vol.38
, pp. 1289-1297
-
-
Carroll, J.S.1
Meyer, C.A.2
Song, J.3
-
73
-
-
18544365698
-
Gene-expression profiles predict survival of patients with lung adenocarcinoma
-
Beer D.G., Kardia S.L., Huang C.C., et al. Gene-expression profiles predict survival of patients with lung adenocarcinoma. Nat Med 2002, 8:816-824.
-
(2002)
Nat Med
, vol.8
, pp. 816-824
-
-
Beer, D.G.1
Kardia, S.L.2
Huang, C.C.3
-
74
-
-
33747878451
-
Gene expression signatures for predicting prognosis of squamous cell and adenocarcinomas of the lung
-
Raponi M., Zhang Y., Yu J., et al. Gene expression signatures for predicting prognosis of squamous cell and adenocarcinomas of the lung. Cancer Res 2006, 66:7466-7472.
-
(2006)
Cancer Res
, vol.66
, pp. 7466-7472
-
-
Raponi, M.1
Zhang, Y.2
Yu, J.3
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