Murine Schnurri-2 controls natural killer cell function and lymphoma development

Leukemia and Lymphoma

Volumn 53, Issue 3, 2012, Pages 479-486

  Yamashita, Junji ^a,b   Iwamura, Chiaki ^a   Mitsumori, Kunitoshi ^c   Hosokawa, Hiroyuki ^a   Sasaki, Tetsuya ^a,b   Takahashi, Munehisa ^b   Tanaka, Hitoshi ^b   Kaneko, Kenji ^b   Hanazawa, Asami ^a   Watanabe, Yukiko ^a   Shinoda, Kenta ^a   Tumes, Damon ^a   Motohashi, Shinichiro ^a   Nakayama, Toshinori ^a  

^a CHIBA UNIVERSITY   (Japan)

^b Research Division   (Japan)

^c TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY   (Japan)

Author keywords

NK cells; Schnnuri2; Spontaneous lymphoma

Indexed keywords

CD27 ANTIGEN; CD3 ANTIGEN; CD69 ANTIGEN; GRANZYME B; INTERLEUKIN 2 RECEPTOR BETA; MESSENGER RNA; PERFORIN; SCHNURRI 2 PROTEIN; STAT3 PROTEIN; STAT5 PROTEIN; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INFILTRATION; CANCER SURVIVAL; CARCINOGENESIS; CAUSE OF DEATH; CELL MEDIATED CYTOTOXICITY; CONTROLLED STUDY; DOWN REGULATION; LUNG; LYMPHOCYTE ACTIVATION; LYMPHOCYTE FUNCTION; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SPLEEN CELL; T CELL LYMPHOMA; WILD TYPE;

ANIMALS; ANTIGENS, CD3; CYTOTOXICITY, IMMUNOLOGIC; DNA-BINDING PROTEINS; GRANZYMES; IMMUNITY, INNATE; IMMUNOLOGIC SURVEILLANCE; INTERLEUKIN-2; KILLER CELLS, NATURAL; LONGEVITY; LUNG; LYMPHOCYTE ACTIVATION; LYMPHOMA, T-CELL; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; NEOPLASM PROTEINS; PERFORIN; SPECIFIC PATHOGEN-FREE ORGANISMS; SPLEEN;

EID: 84857543117     PISSN: 10428194     EISSN: 10292403     Source Type: Journal    
DOI: 10.3109/10428194.2011.625099     Document Type: Article

References (34)

1. Aff olter M, Marty T, Vigano MA., et al. Nuclear interpretation of Dpp signaling in Drosophila. EMBO J 2001;20:3298-3305. (Pubitemid 32634337)
2. A rora K, Dai H, Kazuko SG., et al. Th e Drosophila schnurri gene acts in the Dpp/TGF beta signaling pathway and encodes a transcription factor homologous to the human MBP family. Cell 1995;81:781-790.
3. S taehling-Hampton K, Laughon AS, Hoff mann FM. A Drosophila protein related to the human zinc fi nger transcription factor PRDII/MBPI/HIV-EP1 is required for dpp signaling. Development 1995;121:3393-3403.
4. Kingsley DM. Th e TGF-beta superfamily: new members, new receptors, and new genetic tests of function in diff erent organisms. Genes Dev 1994;8:133-146.
5. W u LC. ZAS: C2H2 zinc fi nger proteins involved in growth and development. Gene Expr 2002;10:137-152.
6. M akino R, Akiyama K, Yasuda J., et al. Cloning and characterization of a c-myc intron binding protein (MIBP1). Nucleic Acids Res 1994;22:5679-5685.
7. R on D, Brasier AR, Habener JF. Angiotensinogen gene-inducible enhancer-binding protein 1, a member of a new family of large nuclear proteins that recognize nuclear factor kappa B-binding sites through a zinc fi nger motif. Mol Cell Biol 1991;11:2887-2895. (Pubitemid 21895670)
8. C ampbell DB, Levitt P. Regionally restricted expression of the transcription factor c-myc intron 1 binding protein during brain development. J Comp Neurol 2003;467:581-592. (Pubitemid 37467132)
9. T akagi T, Harada J, Ishii S. Murine Schnurri-2 is required for positive selection of thymocytes. Nat Immunol 2001;2:1048-1053. (Pubitemid 33069500)
10. A llen CE, Muthusamy N, Weisbrode SE., et al. Developmental anomalies and neoplasia in animals and cells defi cient in the large zinc fi nger protein KRC. Genes Chromosomes Cancer 2002;35:287-298. (Pubitemid 35246987)
11. K imura MY, Hosokawa H, Yamashita M., et al. Regulation of T helper type 2 cell diff erentiation by murine Schnurri-2. J Exp Med 2005;201:397-408. (Pubitemid 40229414)
12. I wamura C, Kimura MY, Shinoda K., et al. Schnurri-2 regulates Th 2-dependent airway infl ammation and airway hyperresponsiveness. Int Immunol 2007;19:755-762. (Pubitemid 47073265)
13. N akayama T, June CH, Munitz TI., et al. Inhibition of T cell receptor expression and function in immature CD4- CD8- cells by CD4. Science 1990;249:1558-1561.
14. Y amashita J, Iwamura C, Sasaki T., et al. Apolipoprotein A-II Suppressed Concanavalin A-Induced Hepatitis via the Inhibition of CD4 T Cell Function. J Immunol 2011;186:3410-3420.
15. S uzuki A, Iwamura C, Shinoda K., et al. Polycomb group gene product Ring1B regulates Th 2-driven airway infl ammation through the inhibition of Bim-mediated apoptosis of eff ector Th 2 cells in the lung. J Immunol 2010;184:4510-4520.
16. K awano T, Cui J, Koezuka Y., et al. Natural killer-like nonspecifi c tumor cell lysis mediated by specifi c ligand-activated Valpha14 NKT cells. Proc Natl Acad Sci U S A 1998;95:5690-5693. (Pubitemid 28224157)
17. N akayama T, Kimura MY. Memory Th 1/Th 2 cell generation controlled by Schnurri-2. Adv Exp Med Biol 2010;684:1-10.
18. S alcedo TW, Azzoni L, Wolf SF., et al. Modulation of perforin and granzyme messenger RNA expression in human natural killer cells. J Immunol 1993;151:2511-2520. (Pubitemid 23264503)
19. van Den Broek ME, Kagi D, Ossendorp F., et al. Decreased tumor surveillance in perforin-defi cient mice. J Exp Med 1996;184:1781-1790. (Pubitemid 26404469)
20. Smyth MJ, Th ia KY, Cretney E., et al. Perforin is a major contributor to NK cell control of tumor metastasis. J Immunol 1999;162:6658-6662. (Pubitemid 29309390)
21. Smyth MJ, Th ia KY, Street SE., et al. Perforin-mediated cytotoxicity is critical for surveillance of spontaneous lymphoma. J Exp Med 2000;192:755-760.
22. Sors A, Jean-Louis F, Pellet C., et al. Down-regulating constitutive activation of the NF-kappaB canonical pathway overcomes the resistance of cutaneous T-cell lymphoma to apoptosis. Blood 2006;107:2354-2363. (Pubitemid 43345555)
23. Jost PJ, Ruland J. Aberrant NF-kappaB signaling in lymphoma: mechanisms, consequences, and therapeutic implications. Blood 2007;109:2700-2707. (Pubitemid 46482061)
24. Horie R. NF-kappaB in pathogenesis and treatment of adult T-cell leukemia/lymphoma. Int Rev Immunol 2007;26:269-281. (Pubitemid 350131623)
25. v an Den Broek MF, Kagi D, Zinkernagel RM., et al. Perforin dependence of natural killer cell-mediated tumor control in vivo. Eur J Immunol 1995;25:3514-3516. (Pubitemid 26004963)
26. Takeda K, Oshima H, Hayakawa Y., et al. CD27-mediated activation of murine NK cells. J Immunol 2000;164:1741-1745. (Pubitemid 30108724)
27. Yang FC, Agematsu K, Nakazawa T., et al. CD27/CD70 interaction directly induces natural killer cell killing activity. Immunology 1996;88:289-293. (Pubitemid 26189313)
28. Hayakawa Y, Smyth MJ. NKG2D and cytotoxic eff ector function in tumor immune surveillance. Seminars Immunol 2006;18:176-185. (Pubitemid 43817565)
29. Guerra N, Tan YX, Joncker NT., et al. NKG2D-defi cient mice are defective in tumor surveillance in models of spontaneous malignancy. Immunity 2008;28:571-580.
30. Salvucci O, Mami-Chouaib F, Moreau JL., et al. Diff erential regulation of interleukin-12- and interleukin-15-induced natural killer cell activation by interleukin-4. Eur J Immunol 1996;26:2736-2741. (Pubitemid 26364853)
31. L in JX, Migone TS, Tsang M., et al. Th e role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15. Immunity 1995;2:331-339.
32. J ohnston JA, Bacon CM, Finbloom DS., et al. Tyrosine phosphorylation and activation of STAT5, STAT3, and Janus kinases by interleukins 2 and 15. Proc Natl Acad Sci U S A 1995;92:8705-8709.
33. Y u CR, Ortaldo JR, Curiel RE., et al. Role of a STAT binding site in the regulation of the human perforin promoter. J Immunol 1999;162:2785-2790. (Pubitemid 29309303)
34. Z hou J, Zhang J, Lichtenheld MG., et al. A role for NF-kappa B activation in perforin expression of NK cells upon IL-2 receptor signaling. J Immunol 2002;169:1319-1325. (Pubitemid 34809174)