Impaired chromatin remodelling at STAT1-regulated promoters leads to global unresponsiveness of Toxoplasma gondii-infected macrophages to IFN-γ

PLoS Pathogens

Volumn 8, Issue 1, 2012, Pages

  Lang, Christine ^a,b   Hildebrandt, Anke ^a   Brand, Franziska ^a   Opitz, Lennart ^a   Dihazi, Hassan ^a   Lüder, Carsten G K ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b ROWETT RESEARCH INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; GAMMA INTERFERON; HISTONE DEACETYLASE INHIBITOR; OLIGONUCLEOTIDE; STAT1 PROTEIN;

ANIMAL CELL; ARTICLE; CELL NUCLEUS; CHROMATIN; DNA SEQUENCE; IN VITRO STUDY; MACROPHAGE; MASS SPECTROMETRY; MOUSE; NONHUMAN; PROTEIN BINDING; PROTEIN LOCALIZATION; TOXOPLASMA GONDII; TOXOPLASMOSIS;

ANIMALS; CHROMATIN ASSEMBLY AND DISASSEMBLY; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HISTONE DEACETYLASE INHIBITORS; HISTONE DEACETYLASES; HOST-PARASITE INTERACTIONS; INTERFERON-GAMMA; MACROPHAGES; MICE; MICE, INBRED BALB C; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROMOTER REGIONS, GENETIC; PROTEIN MULTIMERIZATION; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; TOXOPLASMA; TOXOPLASMOSIS; TRANSCRIPTOME;

MURINAE; TOXOPLASMA; TOXOPLASMA GONDII;

EID: 84857473399     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002483     Document Type: Article

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