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Volumn 8, Issue 8, 2006, Pages 1994-2005

Diverse mechanisms employed by Toxoplasma gondii to inhibit IFN-γ-induced major histocompatibility complex class II gene expression

Author keywords

IFN ; Immune evasion; MHC; Parasite host interaction; Toxoplasma gondii

Indexed keywords

GAMMA INTERFERON; INTERFERON REGULATORY FACTOR 1; INTERLEUKIN 10; LUCIFERASE;

EID: 33748135929     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2006.02.031     Document Type: Article
Times cited : (54)

References (37)
  • 1
    • 0031736936 scopus 로고    scopus 로고
    • Regulation and function of T-cell-mediated immunity during Toxoplasma gondii infection
    • Denkers E., and Gazzinelli R.T. Regulation and function of T-cell-mediated immunity during Toxoplasma gondii infection. Clin. Microbiol. Rev. 11 (1998) 569-588
    • (1998) Clin. Microbiol. Rev. , vol.11 , pp. 569-588
    • Denkers, E.1    Gazzinelli, R.T.2
  • 2
    • 0023937713 scopus 로고
    • Dual regulation of resistance against Toxoplasma gondii infection by Lyt-2+ and Lyt-1+, L3T4+ cells in mice
    • Suzuki Y., and Remington J.S. Dual regulation of resistance against Toxoplasma gondii infection by Lyt-2+ and Lyt-1+, L3T4+ cells in mice. J. Immunol. 140 (1988) 3943-3946
    • (1988) J. Immunol. , vol.140 , pp. 3943-3946
    • Suzuki, Y.1    Remington, J.S.2
  • 3
    • 0026021838 scopus 로고
    • Synergistic role of CD4+ and CD8+ T lymphocytes in IFN-γ production and protective immunity induced by an attenuated Toxoplasma gondii vaccine
    • Gazzinelli R.T., Hakim F.T., Hieny S., Shearer G.M., and Sher A. Synergistic role of CD4+ and CD8+ T lymphocytes in IFN-γ production and protective immunity induced by an attenuated Toxoplasma gondii vaccine. J. Immunol. 146 (1991) 286-292
    • (1991) J. Immunol. , vol.146 , pp. 286-292
    • Gazzinelli, R.T.1    Hakim, F.T.2    Hieny, S.3    Shearer, G.M.4    Sher, A.5
  • 4
    • 0026749880 scopus 로고
    • Simultaneous depletion of CD4+ and CD8+ T lymphocytes is required to reactivate chronic infection with Toxoplasma gondii
    • Gazzinelli R.T., Xu Y., Hieny S., Cheever A., and Sher A. Simultaneous depletion of CD4+ and CD8+ T lymphocytes is required to reactivate chronic infection with Toxoplasma gondii. J. Immunol. 149 (1992) 175-180
    • (1992) J. Immunol. , vol.149 , pp. 175-180
    • Gazzinelli, R.T.1    Xu, Y.2    Hieny, S.3    Cheever, A.4    Sher, A.5
  • 5
    • 0031782098 scopus 로고    scopus 로고
    • Down-regulation of MHC class II molecules and inability to up-regulate class I molecules in murine macrophages after infection with Toxoplasma gondii
    • Lüder C.G.K., Lang T., Beuerle B., and Gross U. Down-regulation of MHC class II molecules and inability to up-regulate class I molecules in murine macrophages after infection with Toxoplasma gondii. Clin. Exp. Immunol. 112 (1998) 308-316
    • (1998) Clin. Exp. Immunol. , vol.112 , pp. 308-316
    • Lüder, C.G.K.1    Lang, T.2    Beuerle, B.3    Gross, U.4
  • 6
    • 0343867201 scopus 로고    scopus 로고
    • Toxoplasma gondii down-regulates MHC class II gene expression and antigen presentation by murine macrophages via interference with nuclear translocation of STAT-1α
    • Lüder C.G.K., Walter W., Beuerle B., Maeurer M.J., and Gross U. Toxoplasma gondii down-regulates MHC class II gene expression and antigen presentation by murine macrophages via interference with nuclear translocation of STAT-1α. Eur. J. Immunol. 31 (2001) 1475-1484
    • (2001) Eur. J. Immunol. , vol.31 , pp. 1475-1484
    • Lüder, C.G.K.1    Walter, W.2    Beuerle, B.3    Maeurer, M.J.4    Gross, U.5
  • 7
    • 0037221830 scopus 로고    scopus 로고
    • Toxoplasma gondii inhibits MHC class II expression in neural antigen-presenting cells by down-regulating the class II transactivator CIITA
    • Lüder C.G.K., Lang C., Giraldo-Velasquez M., Algner M., Gerdes J., and Gross U. Toxoplasma gondii inhibits MHC class II expression in neural antigen-presenting cells by down-regulating the class II transactivator CIITA. J. Neuroimmunol. 134 (2003) 13-24
    • (2003) J. Neuroimmunol. , vol.134 , pp. 13-24
    • Lüder, C.G.K.1    Lang, C.2    Giraldo-Velasquez, M.3    Algner, M.4    Gerdes, J.5    Gross, U.6
  • 8
    • 0021702244 scopus 로고
    • Functional and quantitative alterations in T lymphocyte subpopulations in acute toxoplasmosis
    • Luft B.J., Kansas G., Engleman E.G., and Remington J.S. Functional and quantitative alterations in T lymphocyte subpopulations in acute toxoplasmosis. J. Infect. Dis. 150 (1984) 761-767
    • (1984) J. Infect. Dis. , vol.150 , pp. 761-767
    • Luft, B.J.1    Kansas, G.2    Engleman, E.G.3    Remington, J.S.4
  • 9
    • 0020627424 scopus 로고
    • Toxoplasma gondii: decreased resistance to intracellular bacteria in mice
    • Wing E.J., Boehmer S.M., and Christner L.K. Toxoplasma gondii: decreased resistance to intracellular bacteria in mice. Exp. Parasitol. 56 (1983) 1-8
    • (1983) Exp. Parasitol. , vol.56 , pp. 1-8
    • Wing, E.J.1    Boehmer, S.M.2    Christner, L.K.3
  • 10
    • 0022651613 scopus 로고
    • Association of symptomatic human infection with Toxoplasma gondii with imbalance of monocytes and antigen-specific T cell subsets
    • Sklenar I., Jones T.C., Alkan S., and Erb P. Association of symptomatic human infection with Toxoplasma gondii with imbalance of monocytes and antigen-specific T cell subsets. J. Infect. Dis. 153 (1986) 315-324
    • (1986) J. Infect. Dis. , vol.153 , pp. 315-324
    • Sklenar, I.1    Jones, T.C.2    Alkan, S.3    Erb, P.4
  • 11
    • 0031050035 scopus 로고    scopus 로고
    • Regulation of transcription of MHC class II genes
    • Boss J.M. Regulation of transcription of MHC class II genes. Curr. Opin. Immunol. 9 (1997) 107-113
    • (1997) Curr. Opin. Immunol. , vol.9 , pp. 107-113
    • Boss, J.M.1
  • 12
    • 0028142430 scopus 로고
    • Regulation of MHC class II expression by interferon-γ mediated by the transactivator gene CIITA
    • Steimle V., Siegrist C.-A., Mottet A., Lisowska-Grospierre B., and Mach B. Regulation of MHC class II expression by interferon-γ mediated by the transactivator gene CIITA. Science 265 (1994) 106-109
    • (1994) Science , vol.265 , pp. 106-109
    • Steimle, V.1    Siegrist, C.-A.2    Mottet, A.3    Lisowska-Grospierre, B.4    Mach, B.5
  • 13
    • 0032006255 scopus 로고    scopus 로고
    • Activation of the MHC class II transactivator CIITA by interferon-γ requires cooperative interaction between Stat1 and USF-1
    • Muhlethaler-Mottet A., Di Berardino W., Otten L.A., and Mach B. Activation of the MHC class II transactivator CIITA by interferon-γ requires cooperative interaction between Stat1 and USF-1. Immunity 8 (1998) 157-166
    • (1998) Immunity , vol.8 , pp. 157-166
    • Muhlethaler-Mottet, A.1    Di Berardino, W.2    Otten, L.A.3    Mach, B.4
  • 14
    • 0030840464 scopus 로고    scopus 로고
    • STATs and gene regulation
    • Darnell Jr. J.E. STATs and gene regulation. Science 277 (1997) 1630-1635
    • (1997) Science , vol.277 , pp. 1630-1635
    • Darnell Jr., J.E.1
  • 15
    • 0031570834 scopus 로고    scopus 로고
    • Interferons up-regulate STAT1, STAT2, and IRF family transcription factors gene expression in human peripheral blood mononuclear cells and macrophages
    • Lehtonen A., Matikainen S., and Julkunen I. Interferons up-regulate STAT1, STAT2, and IRF family transcription factors gene expression in human peripheral blood mononuclear cells and macrophages. J. Immunol. 159 (1997) 794-803
    • (1997) J. Immunol. , vol.159 , pp. 794-803
    • Lehtonen, A.1    Matikainen, S.2    Julkunen, I.3
  • 16
    • 0042635767 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis exerts gene-selective inhibition of transcriptional responses to IFN-γ without inhibiting STAT1 function
    • Kincaid E.Z., and Ernst J.D. Mycobacterium tuberculosis exerts gene-selective inhibition of transcriptional responses to IFN-γ without inhibiting STAT1 function. J. Immunol. 171 (2003) 2042-2049
    • (2003) J. Immunol. , vol.171 , pp. 2042-2049
    • Kincaid, E.Z.1    Ernst, J.D.2
  • 17
    • 0033558170 scopus 로고    scopus 로고
    • Dynamic redistribution of STAT1 protein in IFN signaling visualized by GFP fusion proteins
    • Köster M., and Hauser H. Dynamic redistribution of STAT1 protein in IFN signaling visualized by GFP fusion proteins. Eur. J. Biochem. 260 (1999) 137-144
    • (1999) Eur. J. Biochem. , vol.260 , pp. 137-144
    • Köster, M.1    Hauser, H.2
  • 18
    • 0027521572 scopus 로고
    • Interleukin-10-deficient mice develop chronic enterocolitis
    • Kühn R., Löhler J., Rennick D., Rajewsky K., and Müller W. Interleukin-10-deficient mice develop chronic enterocolitis. Cell 75 (1993) 263-274
    • (1993) Cell , vol.75 , pp. 263-274
    • Kühn, R.1    Löhler, J.2    Rennick, D.3    Rajewsky, K.4    Müller, W.5
  • 19
    • 0025719416 scopus 로고
    • Identification of a virulence-associated antigen of Toxoplasma gondii by use of a mouse monoclonal antibody
    • Gross U., Müller W.A., Knapp S., and Heesemann J. Identification of a virulence-associated antigen of Toxoplasma gondii by use of a mouse monoclonal antibody. Infect. Immun. 59 (1991) 4511-4516
    • (1991) Infect. Immun. , vol.59 , pp. 4511-4516
    • Gross, U.1    Müller, W.A.2    Knapp, S.3    Heesemann, J.4
  • 20
    • 0019359890 scopus 로고
    • Infection of murine peritoneal macrophages with Toxoplasma gondii exposed to ultraviolet light
    • Endo T., Pelster B., and Piekarski G. Infection of murine peritoneal macrophages with Toxoplasma gondii exposed to ultraviolet light. Z. Parasitenkd. 65 (1981) 121-129
    • (1981) Z. Parasitenkd. , vol.65 , pp. 121-129
    • Endo, T.1    Pelster, B.2    Piekarski, G.3
  • 21
    • 0021827581 scopus 로고
    • Phagosome acidification blocked by intracellular Toxoplasma gondii
    • Sibley L.D., Weidner E., and Krahenbuhl J.L. Phagosome acidification blocked by intracellular Toxoplasma gondii. Nature 315 (1985) 416-419
    • (1985) Nature , vol.315 , pp. 416-419
    • Sibley, L.D.1    Weidner, E.2    Krahenbuhl, J.L.3
  • 22
    • 0035252656 scopus 로고    scopus 로고
    • Hijacking and exploitation of IL-10 by intracellular pathogens
    • Redpath S., Ghazal P., and Gascoigne N.R.J. Hijacking and exploitation of IL-10 by intracellular pathogens. Trends Microbiol. 9 (2001) 86-92
    • (2001) Trends Microbiol. , vol.9 , pp. 86-92
    • Redpath, S.1    Ghazal, P.2    Gascoigne, N.R.J.3
  • 23
    • 4043119714 scopus 로고    scopus 로고
    • Functional inactivation of immune dendritic cells by the intracellular parasite Toxoplasma gondii
    • McKee A.S., Dzierszinski F., Boes M., Roos D.S., and Pearce E.J. Functional inactivation of immune dendritic cells by the intracellular parasite Toxoplasma gondii. J. Immunol. 173 (2004) 2632-2640
    • (2004) J. Immunol. , vol.173 , pp. 2632-2640
    • McKee, A.S.1    Dzierszinski, F.2    Boes, M.3    Roos, D.S.4    Pearce, E.J.5
  • 24
    • 0029759950 scopus 로고    scopus 로고
    • Role of macrophage-derived cytokines in the induction and regulation of cell-mediated immunity to Toxoplasma gondii
    • Toxoplasma gondii. Gross U. (Ed) Springer, Heidelberg
    • Gazzinelli R.T., Amichay D., Sharton-Kersten T., Grunwald E., Farber J.M., and Sher A. Role of macrophage-derived cytokines in the induction and regulation of cell-mediated immunity to Toxoplasma gondii. In: Gross U. (Ed). Toxoplasma gondii. Curr. Top. Microbiol. Immunol. 219 (1996) 127-139 Springer, Heidelberg
    • (1996) Curr. Top. Microbiol. Immunol. , vol.219 , pp. 127-139
    • Gazzinelli, R.T.1    Amichay, D.2    Sharton-Kersten, T.3    Grunwald, E.4    Farber, J.M.5    Sher, A.6
  • 25
    • 0036210436 scopus 로고    scopus 로고
    • Low responsiveness to IFN-γ, after pretreatment of mouse macrophages with lipopolysaccharides, develop via diverse regulatory pathways
    • Crespo A., Filla M.B., and Murphy W.J. Low responsiveness to IFN-γ, after pretreatment of mouse macrophages with lipopolysaccharides, develop via diverse regulatory pathways. Eur. J. Immunol. 32 (2002) 710-719
    • (2002) Eur. J. Immunol. , vol.32 , pp. 710-719
    • Crespo, A.1    Filla, M.B.2    Murphy, W.J.3
  • 26
    • 0034036767 scopus 로고    scopus 로고
    • Prolonged exposure of mouse macrophages to IFN-β suppresses transcription of the inducible nitric oxide synthase gene: altered availability of transcription factor Stat1α
    • Gao J.J., Filla M.B., Lorsbach R.B., Pace J.L., Crespo A., Russell S.W., and Murphy W.J. Prolonged exposure of mouse macrophages to IFN-β suppresses transcription of the inducible nitric oxide synthase gene: altered availability of transcription factor Stat1α. Eur. J. Immunol. 30 (2000) 1551-1561
    • (2000) Eur. J. Immunol. , vol.30 , pp. 1551-1561
    • Gao, J.J.1    Filla, M.B.2    Lorsbach, R.B.3    Pace, J.L.4    Crespo, A.5    Russell, S.W.6    Murphy, W.J.7
  • 27
    • 0036716776 scopus 로고    scopus 로고
    • Mechanism of entry determines the ability of Toxoplasma gondii to inhibit macrophages proinflammatory cytokine production
    • Butcher B.A., and Denkers E.Y. Mechanism of entry determines the ability of Toxoplasma gondii to inhibit macrophages proinflammatory cytokine production. Infect. Immun. 70 (2002) 5216-5224
    • (2002) Infect. Immun. , vol.70 , pp. 5216-5224
    • Butcher, B.A.1    Denkers, E.Y.2
  • 28
    • 14844352488 scopus 로고    scopus 로고
    • Cutting edge: IL-10-independent STAT3 activation by Toxoplasma gondii mediates suppression of IL-12 and TNF-α in host macrophages
    • Butcher B.A., Kim L., Panapoulos A.D., Watowich S.S., Murray P.J., and Denkers E.Y. Cutting edge: IL-10-independent STAT3 activation by Toxoplasma gondii mediates suppression of IL-12 and TNF-α in host macrophages. J. Immunol. 174 (2005) 3148-3152
    • (2005) J. Immunol. , vol.174 , pp. 3148-3152
    • Butcher, B.A.1    Kim, L.2    Panapoulos, A.D.3    Watowich, S.S.4    Murray, P.J.5    Denkers, E.Y.6
  • 30
    • 0033591635 scopus 로고    scopus 로고
    • Chlamydia inhibits interferon γ-inducible major histocompatibility complex class II expression by degradation of upstream stimulatory factor 1
    • Zhong G., Fan T., and Liu L. Chlamydia inhibits interferon γ-inducible major histocompatibility complex class II expression by degradation of upstream stimulatory factor 1. J. Exp. Med. 189 (1999) 1931-1937
    • (1999) J. Exp. Med. , vol.189 , pp. 1931-1937
    • Zhong, G.1    Fan, T.2    Liu, L.3
  • 31
    • 0034824828 scopus 로고    scopus 로고
    • Toxoplasma gondii and MHC-restricted antigen presentation: on degradation, transport and modulation
    • Lüder C.G.K., and Seeber F. Toxoplasma gondii and MHC-restricted antigen presentation: on degradation, transport and modulation. Int. J. Parasitol. 31 (2001) 1355-1369
    • (2001) Int. J. Parasitol. , vol.31 , pp. 1355-1369
    • Lüder, C.G.K.1    Seeber, F.2
  • 32
    • 0018904013 scopus 로고
    • Antigenemia in recently acquired acute toxoplasmosis
    • Araujo F.G., and Remington J.S. Antigenemia in recently acquired acute toxoplasmosis. J. Infect. Dis. 141 (1980) 144-150
    • (1980) J. Infect. Dis. , vol.141 , pp. 144-150
    • Araujo, F.G.1    Remington, J.S.2
  • 33
    • 0023139203 scopus 로고
    • Detection of circulating antigens in immunocompromised patients during reactivation of chronic toxoplasmosis
    • Candolfi E., Derouin F., and Kien T. Detection of circulating antigens in immunocompromised patients during reactivation of chronic toxoplasmosis. Eur. J. Clin. Microbiol. 6 (1987) 44-48
    • (1987) Eur. J. Clin. Microbiol. , vol.6 , pp. 44-48
    • Candolfi, E.1    Derouin, F.2    Kien, T.3
  • 34
    • 0023096239 scopus 로고
    • Presence of high concentrations of circulating Toxoplasma antigens during acute Toxoplasma infection in athymic nude mice
    • Suzuki Y., and Kobayashi A. Presence of high concentrations of circulating Toxoplasma antigens during acute Toxoplasma infection in athymic nude mice. Infect. Immun. 55 (1987) 1017-1018
    • (1987) Infect. Immun. , vol.55 , pp. 1017-1018
    • Suzuki, Y.1    Kobayashi, A.2
  • 35
    • 0035879107 scopus 로고    scopus 로고
    • IFN-γ overproduction and high level apoptosis are associated with high but not low virulence Toxoplasma gondii infection
    • Gavrilescu L.C., and Denkers E.Y. IFN-γ overproduction and high level apoptosis are associated with high but not low virulence Toxoplasma gondii infection. J. Immunol. 167 (2001) 902-909
    • (2001) J. Immunol. , vol.167 , pp. 902-909
    • Gavrilescu, L.C.1    Denkers, E.Y.2
  • 37
    • 0028032968 scopus 로고
    • Immunopathogenesis of toxoplasmic encephalitis
    • Hunter C.A., and Remington J.S. Immunopathogenesis of toxoplasmic encephalitis. J. Infect. Dis. 170 (1994) 1057-1067
    • (1994) J. Infect. Dis. , vol.170 , pp. 1057-1067
    • Hunter, C.A.1    Remington, J.S.2


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