The time-dependent autophagy protects against apoptosis with possible involvement of Sirt1 protein in multiple myeloma under nutrient depletion

Annals of Hematology

Volumn 91, Issue 3, 2012, Pages 407-417

  Zeng, Rong ^a   He, Jing ^a   Peng, Jin ^b   Chen, Yan ^a   Yi, Sha ^a   Zhao, Fei ^a   Cui, Guohui ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b WUHAN UNIVERSITY   (China)

Author keywords

Apoptosis; Autophagy; Multiple myeloma; Sirt1; Time dependent

Indexed keywords

3 METHYLADENINE; BECLIN 1; CASPASE 3; FLUORESCEIN ISOTHIOCYANATE; LIPOCORTIN 5; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MESSENGER RNA; MONODANSYLCADERVARINE; PROPIDIUM IODIDE; PROTEIN BAX; PROTEIN S6 KINASE 1; REAGENT; S6 KINASE; SIRTUIN 1; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CELL CULTURE; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; CYTOPLASM; DOWN REGULATION; ENZYME ACTIVATION; FLOW CYTOMETRY; FLUORESCENCE; HUMAN; HUMAN CELL; METABOLIC STRESS; MITOCHONDRION; MULTIPLE MYELOMA; MYELOMA CELL; NICK END LABELING; NUTRIENT DEPLETION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; STAINING; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CELL LINE, TUMOR; CULTURE MEDIA; HUMANS; MEMBRANE PROTEINS; MULTIPLE MYELOMA; PROTEINS; SIRTUIN 1; TIME FACTORS;

EID: 84857371921     PISSN: 09395555     EISSN: 14320584     Source Type: Journal    
DOI: 10.1007/s00277-011-1315-z     Document Type: Article

References (41)

1. R Mathew V Karantza-Wadsworth E White 2007 Role of autophagy in cancer Nat Rev Cancer 7 961 967 10.1038/nrc2254 17972889 10.1038/nrc2254 1:CAS:528:DC%2BD2sXhtlCrsLbJ (Pubitemid 350165856)
2. RK Amaravadi CB Thompson 2007 The roles of therapy-induced autophagy and necrosis in cancer treatment Clin Cancer Res 13 7271 7279 10.1158/1078-0432 18094407 10.1158/1078-0432.CCR-07-1595 1:CAS:528:DC%2BD2sXhsVCktr%2FL
3. Y Kondo T Kanzawa R Sawaya S Kondo 2005 The role of autophagy in cancer development and response to therapy Nat Rev Cancer 5 726 734 10.1038/nrc1692 16148885 10.1038/nrc1692 1:CAS:528:DC%2BD2MXpsleksL4%3D (Pubitemid 41486365)
4. T Shintani DJ Klionsky 2004 Autophagy in health and disease: a double-edged sword Science 306 990 995 10.1126/science.1099993 15528435 10.1126/science.1099993 1:CAS:528:DC%2BD2cXptFyju78%3D (Pubitemid 39482894)
5. T Yoshinori C Domenico M Norimasa, et al. 2007 Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis Nat Cell Biol 9 10 1142 1151 10.1038/ncb1634 10.1038/ncb1634 (Pubitemid 47500490)
6. P Codogno AJ Meijer 2005 Autophagy and signaling: their role in cell survival and cell death Cell Death Differ 12 1509 1518 10.1038/sj.cdd.4401751 16247498 10.1038/sj.cdd.4401751 1:CAS:528:DC%2BD2MXhtFCjt7%2FI (Pubitemid 41553987)
7. XH Liang S Jackson M Seaman, et al. 1999 Induction of autophagy and inhibition of tumorigenesis by Beclin 1 Nature 420 672 676 10.1038/45257 (Pubitemid 129516338)
8. D Gozuacik A Kimchi 2004 Autophagy as a cell death and tumor suppressor mechanism Oncogene 23 2891 2906 10.1038/sj.onc.1207521 15077152 10.1038/sj.onc.1207521 1:CAS:528:DC%2BD2cXivFKmsL8%3D (Pubitemid 38638851)
9. JJ Lum DE Bauer M Kong, et al. 2005 Growth factor regulation of autophagy and cell survival in the absence of apoptosis Cell 120 237 248 10.1016/j.cell.2004.11.046 15680329 10.1016/j.cell.2004.11.046 1:CAS:528:DC%2BD2MXht1emuro%3D (Pubitemid 40174766)
10. L Yu F Wan S Dutta S Welsh, et al. 2006 Autophagic programmed cell death by selective catalase degradation Pro Natl Acad Sci USA 103 4952 4957 10.1073/pnas.0511288103 10.1073/pnas.0511288103 1:CAS:528:DC%2BD28XjsVGls7k%3D
11. Y Tsujimoto S Shimizu 2005 Another way to die: autophagic programmed cell death Cell Death Differ 12 1528 1534 10.1038/sj.cdd.4401777 16247500 10.1038/sj.cdd.4401777 1:CAS:528:DC%2BD2MXhtFCjt7%2FL (Pubitemid 41553989)
12. W Bursch A Ellinger C Gerner, et al. 2000 Programmed cell death(PCD): Apoptosis, autophagic PCD, or others? Ann NY Acad Sci 926 1 12 10.1111/j.1749-6632.2000.tb05594 11193023 10.1111/j.1749-6632.2000.tb05594.x 1:CAS:528:DC%2BD3MXnt1altA%3D%3D (Pubitemid 32050138)
13. K Gosselin E Deruy S Martien, et al. 2009 Senescent keratinocytes die by autophagic programmed cell death Am J Pathol 174 423 435 10.2353/ajpath.2009. 080332 19147823 10.2353/ajpath.2009.080332 1:CAS:528:DC%2BD1MXivVWnsb8%3D
14. T Kanzawa L Zhang L Xiao, et al. 2005 Arsenic trioxide induces autophagic cell death in malignant glioma cells by upregulation of mitochondrial cell death protein BNIP3 Oncogene 24 980 991 10.1038/sj.onc.1208095 15592527 10.1038/sj.onc.1208095 1:CAS:528:DC%2BD2MXptlKhtQ%3D%3D (Pubitemid 40313875)
15. T Kanzawa IM Germano T Komata, et al. 2004 Role of autophagy in temozolomide-induced cytotoxicity for maglinant glioma cells Cell Death Differ 11 448 457 10.1038/sj.cdd.4401359 14713959 10.1038/sj.cdd.4401359 1:CAS:528:DC%2BD2cXit12ntb0%3D (Pubitemid 38489422)
16. N Kourtis N Tavernarakis 2009 Autophagy and cell death in model organisms Cell Death Differ 16 21 30 10.1038/cdd.2008.120 19079286 10.1038/cdd.2008.120 1:CAS:528:DC%2BD1cXhsV2it7zJ
17. T Yoshimori 2004 Autophagy: a regulated bulk degradation process inside cells Biochem Biophys Res Commun 313 453 458 10.1016/j.bbrc.2003.07.023 14684184 10.1016/j.bbrc.2003.07.023 1:CAS:528:DC%2BD3sXpvVWmuro%3D (Pubitemid 37543608)
18. B Levine DJ Klionsky 2004 Development by self-digestion: molecular mechanisms and biological functions of autophagy Dev Cell 6 463 477 10.1016/S1534-5807(04)00099-1 15068787 10.1016/S1534-5807(04)00099-1 1:CAS:528:DC%2BD2cXjsFeqsbs%3D (Pubitemid 38456176)
19. DJ Klionsky 2007 Autophagy: from phenomenology to molecular understanding in less than a decade Nat Rev Mol Cell Biol 8 931 937 10.1038/nrm2245 17712358 10.1038/nrm2245 1:CAS:528:DC%2BD2sXhtF2qsL3I (Pubitemid 47622558)
20. S Pattingre A Tassa X Qu, et al. 2005 Bcl-2 anti-apoptotic proteins inhibit Beclin 1-dependent autophagy Cell 122 927 939 10.1016/j.cell.2005.07.002 16179260 10.1016/j.cell.2005.07.002 1:CAS:528:DC%2BD2MXhtVOrurbP (Pubitemid 41345209)
21. M Noboru 2007 Autophagy: process and function Genes Dev 21 2861 2873 10.1101/gad.1599207 10.1101/gad.1599207 (Pubitemid 350133435)
22. S Pattingre L Espert M Biard-Piechaczyk P Codogno 2007 Regulation of macroautophagy by mTOR and Beclin 1 complex Biochimie 10 1016 1026 10.1016/j.biochi.2007.08.014
23. T Noda Y Ohsumi 1998 Tor, a phosphatidylinositol kinase homologue, controls autophagy in yeast J Biol Chem 273 3963 3966 10.1074/jbc.273.7.3963 9461583 10.1074/jbc.273.7.3963 1:CAS:528:DyaK1cXht1ahsr8%3D (Pubitemid 28103257)
24. S Wullschleger R Loewith MN Hall 2006 TOR signaling in growth and metabolism Cell 124 471 484 10.1016/j.cell.2006.01.016 16469695 10.1016/j.cell.2006.01.016 1:CAS:528:DC%2BD28Xhslaqs74%3D (Pubitemid 43199434)
25. K Hara K Yonezawa QP Weng, et al. 1998 Amino acid sufficiency and mTOR regulates p70 S6 kinase and eIF-4EBP1 through a common effector mechanism J Biol Chem 273 14484 14494 10.1074/jbc.273.23.14484 9603962 10.1074/jbc.273.23.14484 1:CAS:528:DyaK1cXjs1Oqs74%3D (Pubitemid 28319170)
26. EJ Kim SJ Um 2008 SIRT1: roles in aging and cancer BMB Rep 10 751 756 10.5483/BMBRep.2008.41.11.751
27. T Liu PY Liu GM Marshall 2009 The critical role of the class III histone deacetylase SIRT1 in cancer Cancer Res 69 5 1702 1705 10.1158/0008-5472.CAN-08- 3365 19244112 10.1158/0008-5472.CAN-08-3365 1:CAS:528:DC%2BD1MXisFSrsbk%3D
28. MC Haigis LP Guarente 2006 Mammalian sirtuins-emerging roles in physiology, aging and calorie restriction Genes Dev 20 2913 2921 10.1101/gad.1467506 17079682 10.1101/gad.1467506 1:CAS:528:DC%2BD28XhtFynu7bJ (Pubitemid 44771725)
29. CX Deng 2009 SIRT1, is it a tumor promoter or tumor suppressor? Int J Biol Sci 5 2 147 152 19173036 10.7150/ijbs.5.147 1:CAS:528:DC%2BD1MXnsl2rur8%3D
30. S Chung H Yao S Caito, et al. 2010 Regulation of SIRT1 in cellular functions: role of polyphenols Arch Biochem Biophys 501 79 90 10.1016/j.abb.2010.05.003 20450879 10.1016/j.abb.2010.05.003 1:CAS:528:DC%2BC3cXhtV2jurrF
31. K Kojima R Ohhashi Y Fujita, et al. 2008 A role for SIRT1 in cell growth and chemoresistance in prostate cancer PC3 and DU145 cells Biochem Biophys Res Commun 373 423 428 10.1016/j.bbrc.2008.06.045 18573234 10.1016/j.bbrc.2008.06. 045 1:CAS:528:DC%2BD1cXoslGmurY%3D
32. B Annette FK Horst PE Hans 1995 Monodansylcadaverine(MDC) is specific in vivo marker for autophagic vacuoles Eur J Cell Biol 66 3 14
33. RC Scott O Schuldiner TP Neufeld 2004 Role and regulation of starvation-induced autophagyin the Drosophila fat body Dev Cell 7 167 178 10.1016/j.devcel.2004.07.009 15296714 10.1016/j.devcel.2004.07.009 1:CAS:528:DC%2BD2cXnsVKntr0%3D (Pubitemid 39145023)
34. JH Zhu C Horbinski F Guo, et al. 2007 Regulation of autophagy by extracellular signal-regulated protein kinases during 1-methyl-4- phenylpyridinium-induced cell death Am J Pathol 170 75 86 10.2353/ajpath.2007. 060524 17200184 10.2353/ajpath.2007.060524 1:CAS:528:DC%2BD2sXhsV2gtbc%3D (Pubitemid 47339191)
35. I Kim S Rodriguez-Enriquez JJ Lemasters 2007 Selective degradation of mitochondria by mitophagy Arch Biochem Biophys 462 245 253 10.1016/j.abb.2007. 03.034 17475204 10.1016/j.abb.2007.03.034 1:CAS:528:DC%2BD2sXmt1ygs70%3D (Pubitemid 46876640)
36. S Mordier C Deval D Bechet, et al. 2000 Leucine limitation induces autophagy and activation of lysosome-dependent proteolysis in C2C12 myotubes through a mammalian target of rapamycin-independent signaling pathway J Biol Chem 275 29900 29906 10.1074/jbc.M003633200 10893413 10.1074/jbc.M003633200 1:CAS:528:DC%2BD3cXmvFKjur4%3D (Pubitemid 32043876)
37. T Kanazawa I Taneike R Akaishi, et al. 2004 Amino acids and insulin control autophagic proteolysis through different signaling pathways in relation to mTOR in isolated rat hepatocytes J Biol Chem 279 8452 8459 10.1074/jbc.M306337200 14610086 10.1074/jbc.M306337200 1:CAS:528: DC%2BD2cXhsFeis7s%3D (Pubitemid 38294738)
38. I Kim W Xu JC Reed 2008 Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities Nat Rev Drug Discov 7 12 1013 1030 10.1038/nrd2755 19043451 10.1038/nrd2755 1:CAS:528:DC%2BD1cXhsVenu7%2FM
39. VI Rasheva PM Domingos 2009 Cellular responses to endoplasmic reticulum stress and apoptosis Apoptosis 14 8 996 1007 10.1007/s10495-009-0341-y 19360473 10.1007/s10495-009-0341-y
40. J Ford M Jiang J Milner 2005 Cancer-specific functions of SIRT1 enable human epithelial cancer cell growth and survival Cancer Res 65 10457 10463 10.1158/0008-5472.CAN-05-1923 16288037 10.1158/0008-5472.CAN-05-1923 1:CAS:528:DC%2BD2MXht1Wgu7%2FP (Pubitemid 41743740)
41. JS Carew ST Nawrocki CN Kahue, et al. 2007 Targeting autophagy augments the anticancer activity of the histone deacetylase inhibitor SAHA to overcome Bcr-Abl-mediated drug resistance Blood 110 313 322 10.1182/blood-2006-10-050260 17363733 10.1182/blood-2006-10-050260 1:CAS:528:DC%2BD2sXnsVaitrw%3D (Pubitemid 47026849)