Interactions of Bordetella pertussis adenylyl cyclase toxin CyaA with calmodulin mutants and calmodulin antagonists: Comparison with membranous adenylyl cyclase i

Biochemical Pharmacology

Volumn 83, Issue 7, 2012, Pages 839-848

  Schuler, Dominik ^a   Lübker, Carolin ^a   Lushington, Gerald H ^b   Tang, Wei Jen ^c   Shen, Yuequan ^d   Richter, Mark ^b   Seifert, Roland ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b UNIVERSITY OF KANSAS   (United States)

^c UNIVERSITY OF CHICAGO   (United States)

^d NANKAI UNIVERSITY   (China)

Author keywords

Adenylyl cyclase; Bordetella pertussis; Calmodulin; Calmodulin antagonists; Fluorescence spectroscopy

Indexed keywords

ADENYLATE CYCLASE TOXIN; ADENYLYL CYCLASE TOXIN CYAA; BACTERIAL ENZYME; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE; CALMIDAZOLIUM; CALMODULIN; CALMODULIN INHIBITOR; CYCLIC AMP; LEUCINE; METHIONINE; N (6 AMINOHEXYL) 5 CHLORO 1 NAPHTHALENESULFONAMIDE; PERTUSSIS TOXIN; TRIFLUOPERAZINE; TRYPTOPHAN; UNCLASSIFIED DRUG;

ARTICLE; BORDETELLA PERTUSSIS; CATALYSIS; COMPARATIVE STUDY; CONTROLLED STUDY; EXAMINATION; FLUORESCENCE RESONANCE ENERGY TRANSFER; MUTANT; NONHUMAN; PERTUSSIS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INTERACTION;

ADENYLATE CYCLASE; ADENYLATE CYCLASE TOXIN; BINDING, COMPETITIVE; BORDETELLA PERTUSSIS; CALMODULIN; CATALYSIS; CELL MEMBRANE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; ESCHERICHIA COLI; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMANS; IMIDAZOLES; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MUTATION; PROTEIN BINDING; SULFONAMIDES; TRIFLUOPERAZINE; VIRULENCE; WHOOPING COUGH;

EID: 84857371358     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2012.01.005     Document Type: Article

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