Novel inhibitors of nitric oxide synthase with antioxidant properties

European Journal of Medicinal Chemistry

Volumn 49, Issue , 2012, Pages 118-126

  Salerno, Loredana ^a   Modica, Maria N ^a   Romeo, Giuseppe ^a   Pittalà, Valeria ^a   Siracusa, Maria A ^a   Amato, Maria E ^a   Acquaviva, Rosaria ^a   Di Giacomo, Claudia ^a   Sorrenti, Valeria ^a  

^a UNIVERSITY OF CATANIA   (Italy)

Author keywords

Antioxidants; eNOS; Ethanones; Imidazoles; nNOS; NOS inhibitors

Indexed keywords

1 (4 NITROPHENYL) 2 (1H 1,2,4 TRIAZOL 1 YL) ETHANONE; 1 (4 NITROPHENYL) 2 (2 PROPYL 1H IMIDAZOL 1 YL) ETHANONE; 2 (1H BENZIMIDAZOL 1 YL) 1 (4 NITROPHENYL) ETHANONE; 2 (1H IMIDAZO[4,5 B]PYRIDIN 1 YL) 1 (4 NITROPHENYL) ETHANONE; 2 (1H IMIDAZOL 1 YL) 1 (4 TRIFLUOROMETHYLSULFONYLPHENYL) ETHANONE; 2 (2H 7 NITROINDAZOL 2 YL) 1 (4 NITROPHENYL) ETHANONE; 2 (2H BENZOTRIAZOL 2 YL) 1 (4 NITROPHENYL) ETHANONE; 2 (2H INDAZOL 2 YL) 1 (4 NITROPHENYL) ETHANONE; 2 (3H IMIDAZO[4,5 B]PYRIDIN 3 YL) 1 (4 NITROPHENYL) ETHANONE; 2 (4 METHYL 1H IMIDAZOL 1 YL) 1 (4 NITROPHENYL) ETHANONE; 2 (4,5 DIMETHYL 1H BENZIMIDAZOL 1 YL) 1 (4 NITROPHENYL) ETHANONE; ANTIOXIDANT; CYTOCHROME P450; ENDOTHELIAL NITRIC OXIDE SYNTHASE; IMIDAZOLE DERIVATIVE; LIPID HYDROPEROXIDE; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; NITROGEN; SUPEROXIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; IN VITRO STUDY; LIPID PEROXIDATION; NONHUMAN; RAT;

ANIMALS; ANTIOXIDANTS; ENZYME INHIBITORS; HUMANS; IMIDAZOLES; LIPID PEROXIDATION; NITRIC OXIDE SYNTHASE TYPE I; NITRIC OXIDE SYNTHASE TYPE III; RATS;

EID: 84857233023     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2012.01.002     Document Type: Article

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